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Reposted by Sarah Doom

The Daily Show @thedailyshow.com · 3d

The following is REAL footage from Portland, 2025. Viewer discretion is advised.

Sarah Doom @sarahdoom.bsky.social · 2d

I want to see the Rockettes confronting ice in NYC and other silly non-threatening spectacle pushing these dudes back into their mom’s basement so they can play war in a video game instead of on real people.

Sarah Doom @sarahdoom.bsky.social · 2d

This is the correct response. Expose the MAGA narrative as a lie.
Make MAGA look weird again.

The Oregonian @oregonian.com · 2d

Things are happening at Portland's ICE facility tonight.

Read more of our protest coverage here: www.oregonlive.com/crime/2025/1...

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Reposted by Sarah Doom

Daniel Knowles @dlknowles.bsky.social · 5d

Good reporting on the South Shore raid from South Side weekly here.

Confirms one thing I was told but didn't put in my own piece because I didn't have a second source and it seemed too insane: border agents segregated arrested residents by race

southsideweekly.com/federal-agen...

Federal Agents Storm South Shore Building, Detaining Families and Children

Families were woken by flashbangs and helicopters as hundreds of federal agents raided their homes. Days later, neighbors are still searching for the missing.

southsideweekly.com

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Melanie D’Arrigo @darrigomelanie.bsky.social · 5d

I feel like this photo of masked, armed men pepper spraying a pastor protecting his community is going to be a defining picture of this moment in America for a long, long time.

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Mitchell R. Vollger @mrvollger.bsky.social · 13d

@mollyschumer.bsky.social if the data is pre SPQR chemistry I would recommend fibertools. If it’s new data then you can use Jasmine from Pacbio, Andrew and I spent a fair amount of time looking at the Jasmine results and they look good. And it will all still work with downstream fibertools commands

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Reposted by Sarah Doom

PacBio @pacbio.bsky.social · 10d

Did you know? Revio & Vega include on-instrument 6mA calling for the Fiber-seq chromatin accessibility assay. Thanks to Fiber-seq expert @mrvollger.bsky.social for the thoughtful evaluation and recommendation.

Reagents for the assay are also available from our friends at EpiCypher: bit.ly/42YwGQE

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Sarah Doom @sarahdoom.bsky.social · 10d

Recent app note published www.pacb.com/wp-content/u...

www.pacb.com

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Reposted by Sarah Doom

kottke.org @kottke.org · 12d

I really appreciated this thoughtful piece about Ta-Nehisi Coates & Ezra Klein. Andrea Pitzer says “lost” folks like Klein “don’t have a clear idea how this moment fits into history and what it is exactly that they’re doing”. [degenerateart.beehiiv.com]

You don’t have to swallow frogs

Klein and Coates show that if you don’t know what your core beliefs are, you’re going to get played.

degenerateart.beehiiv.com

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Sarah Doom @sarahdoom.bsky.social · 20d

We are enabling custom panels. PureTarget delivers high depth native DNA and is suited for challenging genes if you want to avoid PCR or where methylation matters. We have enabled high throughput processing with an automation kit and scripts on Hamilton. Learn more - www.pacb.com/technology/p...

PureTarget - PacBio

PureTarget uses the CRISPR-Cas9 system to generate targeted native DNA libraries. This amplification-free approach retains epigenetic signals and has no PCR artifacts or errors.

www.pacb.com

Sarah Doom @sarahdoom.bsky.social · 20d

I'm super excited to announce the new PureTarget kits from @pacbio.bsky.social are out! We have a new carrier screening panel and updated repeat expansion panels plus variant calling software to support both.

Press release - www.pacb.com/press_releas...

This link will take you to a page that’s not on LinkedIn

lnkd.in

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Sarah Doom @sarahdoom.bsky.social · Aug 20

Doooooom is back! I’m going to be a panelist for Oral History Live! Roundtable with Boston Roller Derby. It’s the 20th anniversary of the league I helped found. It’s a virtual event, you can sign up here www.eventbrite.com/e/oral-histo...

Oral History Live! Roundtable with Boston Roller Derby

Celebrate the 20th anniversary of Boston Roller Derby with The History Project and Frankie de la Cretaz!

www.eventbrite.com

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The New York Times @nytimes.com · Aug 2

Breaking News: A federal appeals court upheld a decision that temporarily halted agents from arresting and detaining L.A. immigrants without probable cause.

Judges Keep Restrictions on Los Angeles Immigration Arrests

An appellate panel upheld a finding that federal agents appeared to rely exclusively on race and other factors, such as speaking Spanish, in making arrests.

nyti.ms

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PacBio @pacbio.bsky.social · Jul 29

Quest Diagnostics launched a new test for ataxia using long-read sequencing based on the PacBio #PureTarget method. It can uncover hidden genetic causes of disease, including repeat expansions often missed by other tools.

Details here: bit.ly/4fcu4DV

#PacBio

Athena Diagnostics Improves Ataxia Movement Disorder Testing with Novel Long-Read Gene Sequencing

New test utilizes technology based on PacBio's PureTarget sequencing method to uncover genetic causes of disease BOSTON, July 29, 2025 /PRNewswire/ -- Athena Diagnostics, the specialty neurology...

bit.ly

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Sarah Doom @sarahdoom.bsky.social · Jul 29

This announcement is huge. If you live in the US, chances are you have used Quest Diagnostics for some medical test, they serve 1 in 3 American adults every year. It’s incredibly gratifying to work on products with this kind of impact.

Sarah Doom @sarahdoom.bsky.social · Jul 29

Some exciting professional news: Athena Diagnostics, Inc. developed an LDT using PacBio's PureTarget technology (my product!!) and HiFi sequencing on the Revio, which improves Ataxia Diagnostics for some of the most challenging genes in the human genome. Read the press release here: lnkd.in/g-ec-ECq

This link will take you to a page that’s not on LinkedIn

lnkd.in

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Aaron Reichlin-Melnick @reichlinmelnick.bsky.social · Jul 12

🚨Federal judge orders DHS to limit “roving patrols” in Los Angeles.

The judge finds that the evidence shows that DHS officers are racially profiling people to demand their papers, which all sides agree is illegal, and orders DHS to stop those unlawful practices.

What the federal government would have this Court believe—in the face of a mountain of evidence presented in this case—is that none of this is actually happening.
Most of the questions before this Court are fairly simple and non-controversial, and both
sides in this case agree on the answers.
• May the federal government conduct immigration enforcement— even large scale immigration enforcement-in Los Angeles? Yes, it may.
• Do all individuals regardless of immigration status— share in the rights guaranteed by the Fourth and Fifth Amendments to the Constitution? Yes, they do.
• Is it illegal to conduct roving patrols which identify people based upon race alone, aggressively question them, and then detain them without a warrant, without their consent, and without reasonable suspicion that they are without status? Yes, it is.
• Is it unlawful to prevent people from having access to lawyers who can help them in immigration court? Yes, it is.
There are really two questions in controversy that this Court must decide today.
First, are the individuals and organizations who brought this lawsuit likely to succeed in
proving that the federal government is indeed conducting roving patrols without reasonable suspicion and denying access to lawyers? This Court decides—based on all the evidence presented-that they are.
And second, what should be done about it? The individuals and organizations who have brought this lawsuit have made a fairly modest request: that this Court order the federal government to stop.

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Sarah Doom @sarahdoom.bsky.social · Jul 12

10 days relief from indiscriminate terror www.nytimes.com/2025/07/11/u...

Judge Blocks Trump Administration Tactics in L.A. Immigration Raids

www.nytimes.com

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Reposted by Sarah Doom

Josh Marshall @joshtpm.bsky.social · Jul 5

Harvard sociologist/polisci Theda Skocpol explains how the vast expansion of ICE in BBB may be Trump's secret weapon to overcome the barriers of federalism and complete his autocratic takeover of the American state. (History from Germany & Hungary in 20s/30s.) talkingpointsmemo.com/edblog/criti...

Critical Read About the BBB, Federalism and the Future of American Democracy

TPM Reader TS (Harvard sociologist/political scientist Theda Skocpol) and I often compared...

talkingpointsmemo.com

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Kevin M. Kruse @kevinmkruse.bsky.social · Jun 15

The Tea Party protests in April 2009 had about a third of a million people involved, and the political media treated it like a game changer for the Obama presidency.

The No Kings rallies were AT LEAST ten times bigger than the Tea Party protests. Will the press keep pretending Trump is popular?

G Elliott Morris @gelliottmorris.com · Jun 15

Based on crowd-sourced records of No Kings Day event turnout, and extrapolating for the cities where we don't have data yet, it looks like roughly 4-6 million people protested Trump across the U.S. yesterday. That's nearly 2% of the U.S. pop!

Mobilized anti-Trump resistance is exceeding 2017 levels

"No Kings Day" protests turn out millions

Our unofficial estimate is that around 4 million people attended a protest event yesterday. Anti-Trump resistance is outpacing 2017.

www.gelliottmorris.com

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The Women's Game @womensgamemib.bsky.social · Jun 15

Ahead of tonight’s Angel City match, the club stands with the city of LA. Fans found these shirts at their seats and together with the players are showing that Los Angeles is for everyone ❤️

📷: @angelcity.com