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pacbio.bsky.social
PacBio
@pacbio.bsky.social
Our mission is to enable the promise of genomics to better human health by creating the world’s most advanced sequencing technologies.
Pinned
A little birdie told us we should migrate to bluer skies. 😉 Hello Bluesky world. 👋🌎 Please re-share this post so we can follow you and help to grow the genomics community on here! 🧬✨
Webinar: Scaling HiFi genomes and multiomic discovery with SPRQ-Nx.

Learn how SPRQ-Nx chemistry on the Revio system enables expanded methylation calling and supports population and clinical research, with real-world data from early-access customers.

Register here: bit.ly/4qLqV2Q

#PacBio #SPRQNx
January 27, 2026 at 6:14 PM
PacBio is at ExCeL London for FOG2026!📍 Booth 165
Come see HiFi long-read sequencing + #Revio up close.
Take part in Magenta Moments: wear magenta → snap a pic → post + tag PacBio + use #FOG2026 to enter.
🏆 Live prize draw: Jan 29, 1:00 PM @ Booth 165
Learn more: bit.ly/3MAm7y1
#HiFiSequencing
January 27, 2026 at 10:35 AM
🎬✨Now streaming: BEYOND THE BENCH

This season features:
• Santosha Vardhana on immune cell exhaustion and RNA splicing
• Andor Kiss on bringing HiFi into teaching
• Birgitt Schüele on repeat expansions across populations

Press play → bit.ly/4oLrOXu

#BeyondTheBench #PacBio #TheresHiFiForThat
January 26, 2026 at 8:45 PM
We’re excited to be part of the launch of Diploid Genomics. We share the view that the future of genomics is diploid, combining highly accurate long-read sequencing with AI to deliver more precise, actionable insights in research and healthcare.

Read more: prn.to/4r52UTX

#DiploidGenomes #PacBio
Genomics pioneer J. Craig Venter launches Diploid Genomics, Inc. (DGI), ushering in a new era in human genomics
/PRNewswire/ -- Diploid Genomics, Inc. (DGI), an AI-driven advanced genomics analytics company, launches in partnership with Healthier Capital, a leading...
prn.to
January 23, 2026 at 7:51 PM
What’s next for genomics in 2026?
 
In Bio-IT World’s trendspotting feature, #PacBio CEO Christian Henry shares how affordable, highly accurate long-read genomes are set to power population studies, AI development, and emerging clinical research.
 
Read more: bit.ly/451jbRu
January 23, 2026 at 5:16 PM
DAF-seq uses #PacBio HiFi sequencing to map chromatin at single-cell, single-molecule, and single-haplotype resolution. Researchers uncover how transcription factors interact on DNA and link sequence changes to regulatory effects.

Read more here: bit.ly/4a8bo7b

#Epigenomics #SingleCell #Chromatin
Publication spotlight: HiFi sequencing enables haplotype-specific chromatin mapping from single cells using DAF-seq - PacBio
This publication spotlight highlights a recent paper that represents a major methodological advance in single-cell epigenomics.
https://bit.ly/4a8bo7b"
January 22, 2026 at 8:34 PM
A 1,000-sample Radboud study shows HiFi WGS can help replace multiple clinical tests while enabling an increase in diagnostic findings, pointing to clear evidence that long reads are on track for first-line use.

Ready the study here: bit.ly/4jUxEF9

#PacBio #HiFisequencing #ClinicalGenomics
Clinical long-read genome sequencing for rare disease diagnostics
Background Diagnostic evaluation of rare genetic disorders continues to rely on multiple test modalities, despite the increasing use of short-read exome or genome sequencing as first-tier tests. Long-...
bit.ly
January 22, 2026 at 5:21 PM
Less than one week to go 🎬✨

BEYOND THE BENCH explores how scientists think through uncertainty by stepping outside the lab to understand the minds behind the work.

✅ Immune systems
✅ Natural biological systems
✅ Rare disease research

Don’t miss the premiere -> bit.ly/4oLrOXu
January 21, 2026 at 4:24 PM
How can HiFi sequencing accelerate #biopharma R&D?

Experts from Pfizer, GSK, AstraZeneca, and more share how #PacBio HiFi supports AAV vector characterization, vaccine development, antibody screening, and Iso-Seq for therapeutic design.

Watch on-demand here: bit.ly/49BMHOY
January 20, 2026 at 7:49 PM
Catch 4 presentations featuring HiFi data at #FOG2026 on Jan 28 with Anna Lindstrand, @robpitceathly.bsky.social, @whaerty.bsky.social, and @adameur.bsky.social. Learn how #LongReadSequencing is enabling diagnostics and uncovering new therapeutic opportunities.

Full details here: bit.ly/3MAm7y1
January 20, 2026 at 11:56 AM
Join #PacBio for an #ASHG Digital CoLab on how long read sequencing uncovers structural variants linked to disease. Hear insights from All of Us data and how HiFi WGS supports population scale analysis. Live for ASHG members. On demand later.

Register: bit.ly/3Nh1G9T
January 16, 2026 at 8:05 PM
2025 was a milestone year for HiFi sequencing. 🧬✨

From clinical research advances to multiomics, ultra low input workflows, and large scale genomics, see how HiFi made headlines and what these breakthroughs are shaping next.

Read the full year in review: bit.ly/49qDsmb

#PacBio #HiFisequencing
A year in review: HiFi in the Headline - PacBio
PacBio drove technical advances, expanded access to HiFi sequencing, and helped researchers answer some of genomics’ most important questions.
https://bit.ly/49qDsmb"
January 16, 2026 at 5:12 PM
Reposted by PacBio
The new @pacbio.bsky.social Vega™ sequencer is arrived to the Fundació Fisabio sequencing and bioinformatics service. This instrument will completely transform the landscape of long‑read sequencing to everyone. 60 Gb per run that allows us to observe genomics from a completely new perspective
January 16, 2026 at 12:40 PM
Meet the 2025 Epigenetics SMRT Grant recipients, awarded with our co-sponsor @epicypher.bsky.social!

Learn how Fiber-seq is being applied to study chromatin organization, gene regulation, and complex disease mechanisms, with additional runner up research featured in the blog: bit.ly/4qq6N6c
2025 Epigenetics SMRT Grant Awardees - PacBio
Announcing the 2025 Epigenetics SMRT Grant winners whose research focuses on understanding chromatin structure and gene regulation.
https://bit.ly/4qq6N6c"
January 15, 2026 at 8:01 PM
Apply for the 2025 Immuno SMRT Grant and accelerate your #immunology or #immunotherapy research with PacBio HiFi sequencing via the ProfilAIR immune repertoire profiling assay. Three winners will receive sequencing on two Vega SMRT Cells.

Apply: bit.ly/4pKhgIG

#PacBio
January 15, 2026 at 4:11 PM
That’s a wrap for #PAG33! 🐾 🧬 🌱

Thanks to everyone who visited the PacBio booth, joined our workshop, and celebrated with us at our PAG party. We loved the conversations, connections, and time spent with this incredible genomics community.

#PacBio
January 14, 2026 at 8:31 PM
Don’t miss this spotlight talk featuring Jeremy Wilkinson from #PacBio during #PAG33, starting in one hour! 🌱🧬

Learn how HiFi long-read sequencing enables high-resolution microbiome analysis across plant, animal, and environmental systems.

🕡 6:20 PM | Pacific H-I Room
January 14, 2026 at 1:20 AM
Last chance to visit #PacBio at #PAG33! 🌱🧬

Stop by Booth 219 today to play our scavenger hunt for a chance to win a Labubu, check out additional prizes, and chat with PacBio experts about HiFi sequencing and Vega demos. Don’t miss it!
January 13, 2026 at 6:38 PM
PacBio announced a collaboration with n-Lorem Foundation and EspeRare to support individualized ASO therapies for ultra-rare genetic diseases. Long-read WGS will guide target validation, molecular characterization, and n-of-1 therapy development.

🔗 Press release here: bit.ly/3NsBCbH
January 13, 2026 at 5:15 PM
We’re proud to support UW Medicine & Seattle Children’s using #PacBio HiFi WGS to study Sudden Unexplained Death in Childhood. 200 parent–child trios will be sequenced on Revio with SPRQ-Nx to resolve complex variants and improve diagnostic yield.

Press release here: bit.ly/49k16kc
January 13, 2026 at 3:00 PM
GIVEAWAY at #FOG2026: join our Magenta Moments challenge 🩷
To enter: wear something magenta, snap a pic, and post on Bluesky using #FOG2026 + tag @PacBio.

🏆 Bonus prizes for the most creative magenta looks
⏰ Winners drawn LIVE: 29 Jan, 1 PM at our booth

Learn more: bit.ly/3MAm7y1
#HiFiSequencing
January 13, 2026 at 11:06 AM
The PacBio PAG 2026 party has begun! 🎉🌱🐄 We’re excited for a night of great conversation, connections, and celebrating the collaborations that make plant and animal genomics so inspiring.

#PAG33 #PacBio #PAG2026
January 13, 2026 at 3:04 AM
Dan Portik from #PacBio presents work on strand-specific 5hmC methylated base detection using PacBio HiFi sequencing, highlighting approaches for accurate epigenetic analysis with long reads.

See it today at #PAG33 — Poster P051, 3:00–4:30 PM.
January 12, 2026 at 11:18 PM
Thanks to everyone who joined our PacBio workshop today! 🌱🐄

We loved sharing how HiFi sequencing and SPRQ-Nx chemistry are advancing multiomic discoveries across genomes and populations. Stop by Booth #219 to continue the conversation!

#PAG33 #PacBio #PAG2026
January 12, 2026 at 11:01 PM
Reposted by PacBio
Jeremy Schmutz at HudsonAlpha is the last talk of the @pacbio.bsky.social workshop at #PAG33 to talk about the cornucopia of genomics PacBio provides including beta testing results from SPRQ-Nx reusable SMRT Cells.
January 12, 2026 at 10:38 PM