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pacbio.bsky.social
PacBio
@pacbio.bsky.social
Our mission is to enable the promise of genomics to better human health by creating the world’s most advanced sequencing technologies.
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A little birdie told us we should migrate to bluer skies. 😉 Hello Bluesky world. 👋🌎 Please re-share this post so we can follow you and help to grow the genomics community on here! 🧬✨
One year in, Vega is now powering labs in 17 countries, helping teams adopt HiFi sequencing quickly with simple, reliable workflows.

If you're exploring long-read sequencing or considering Vega for your lab, start with our Sequencing 101 guide: bit.ly/4gGkp9t

#PacBio #Vega #HiFisequencing
November 25, 2025 at 4:41 PM
Join us in Doha for Sidra Medicine #PacBio Tech Day and see how HiFi long-read sequencing is driving progress in population and clinical genomics. Hear from PacBio experts and learn about applications from whole genomes to single-cell analysis.

Register now: bit.ly/3KoFtW5

#AllianceGlobal
November 25, 2025 at 7:55 AM
Reposted by PacBio
Subtle differences in repeat motifs can cause drastic diff in disease onset: using @pacbio.bsky.social PureTarget amp-free identifies non-canonical repeats and its ratio assoc. with disease onset for Spinocerebellar ataxia type 10 (SCA10)

www.neurology.org/doi/full/10....
Novel ATXN10 Repeat Motif Patterns in Peruvian Families Modify Disease Onset | Neurology Genetics
ObjectivesSpinocerebellar ataxia type 10 (SCA10) is an autosomal-dominant disorder caused by intronic expansions of pentanucleotide repeats in the ATXN10 gene. While various repeat motifs have been de...
www.neurology.org
November 24, 2025 at 8:54 PM
💫 SPRQ-Nx is here. The first reagents for Revio just shipped to four U.S. beta sites, now testing how the new chemistry delivers comprehensive genomes for under $300 with a more sustainable workflow. Expanded access and new capabilities land in 2026.

Sign up for early access: pacb.com/techroadmap
November 24, 2025 at 5:35 PM
When you're spending long nights in the lab you need accurate data you can count on and caffeine and snacks.

Download our free Seq 101 guide to see how HiFi can simplify your workflow and help you get clearer answers, no matter what time of day it is: bit.ly/4gGkp9t

#PacBio #TheresHiFiForThat
November 21, 2025 at 8:08 PM
@epicypher.bsky.social's Fiber-seq paired with #PacBio HiFi sequencing offers a single-assay, multiomic view of chromatin by capturing sequence, accessibility, methylation, and protein interactions together. See how this approach improves chromatin insights.

Read the full blog here: bit.ly/3JIKrgg
How pairing EpiCypher’s Fiber-seq with HiFi sequencing delivers an all-in-one multiomic view - PacBio
Fiber-seq with PacBio HiFi sequencing is changing how researchers study epigenetics, advancing discoveries in development and disease.
bit.ly
November 20, 2025 at 5:55 PM
#Antimicrobial resistance is a global threat but understanding it starts with complete data. #PacBio HiFi reveals more complete plasmids, resistance genes, & mobile elements with high accuracy. Let’s sequence smarter to fight antimicrobial resistance.

🔗 bit.ly/4rgthrd

#AMR
November 19, 2025 at 10:31 PM
Just 5 spots left! Apply for your chance to attend a 2026 genomics conference with flights, hotel, and registration covered. Meet HiFi sequencing experts and take your research further.

Apply now: bit.ly/4oJQxvy

#PacBio #TheresHiFiForThat #HiFisequencing #Conferences
November 19, 2025 at 7:04 PM
Tired of repeating experiments and missing the full picture? Complex regions like repeat expansions, GC-rich areas, and structural variants can stump short reads. HiFi long reads capture complete, accurate sequences in one run.

Download our Seq 101 guide: bit.ly/4gGkp9t

#TheresHiFiForThat
November 18, 2025 at 8:30 PM
Just yesterday, Radboudumc shared that they are launching a test to better understand genetic causes of rare disease.

In this video, Radboudumc researchers explain why long-read sequencing is an important step in their scientific work.

Details here: bit.ly/3LO1Swk

#PacBio #RareDisease #Revio
November 18, 2025 at 4:25 PM
Reposted by PacBio
Long-read genome sequencing is new first-tier generic test in diagnostics of rare diseases

So satisfying to see a long journey end in best-possible diagnostic test for patients with rare diseases @radboudumc.bsky.social.

www.radboudumc.nl/en/news-item...

(1/n)
World first: Radboudumc pioneers new genetic test in clinical practice - New test is faster, more efficient, and provides more diagnoses for rare diseases
17 November 2025
www.radboudumc.nl
November 17, 2025 at 8:29 AM
Radboud University Medical Center becomes the first institution in Europe to launch a genetic test that will use #PacBio HiFi sequencing in pre-clinical practice, bringing hope to rare disease families for faster, clearer answers.

Accuracy changes everything.

🔗 Full announcement: bit.ly/3LO1Swk
November 17, 2025 at 4:58 PM
Reposted by PacBio
Someone give the @pacbio.bsky.social marketing team all the awards! The first image here is the PacBio Vega (yes, on a bench- they can now fit on benchtops!) and the second 2 are PacBio Vega socks. How good are these? Like, the data I just got back is also spectacular, but look at these!!! #pacbio
November 14, 2025 at 2:37 PM
Poster presentations are happening now during #AMPath25 in the exhibit hall!

Check out Poster G007 with Sarah Kingan from #PacBio, highlighting long-read sequencing panels to tackle challenging germline targets for carrier screening and repeat expansion disease research.
November 15, 2025 at 2:15 PM
Last call to join our #HiFisequencing for antibody development webinar Tuesday, November 18. Learn how full-length reads with 99.9 percent accuracy accelerate antibody discovery and improve clone selection.

Secure your spot today: bit.ly/4oDrUR6

#PacBio #AntibodyDevelopment
November 14, 2025 at 8:41 PM
Thank you to everyone who joined the #PacBio Industry Spotlight at #AMPath2025! We covered how HiFi targeted and whole genome sequencing helps labs detect complex variants, streamline genetic testing, and deliver more complete answers for clinical and translational research.
November 14, 2025 at 6:49 PM
⏳ One hour to go! Join PacBio on Stage #1 at AMP for our Industry Spotlight. See how HiFi sequencing resolves complex variants, repeat expansions, and structural changes across oncology, neurology, and carrier screening.

Full details here: bit.ly/47Ubb6y

#AMPath25 #PacBio #AMP2025
November 14, 2025 at 4:40 PM
At ASHG, Gabriel Manzo shared how seeing the faces behind the science makes it feel more personal and real.

Want to experience it yourself? Apply for the 2026 Genomics Conference Giveaway for your chance to attend a conference of your choice: bit.ly/4oJQxvy

#PacBio #TheresHiFiForThat
November 13, 2025 at 8:49 PM
Attending AMP 2025? Visit booth #843 to see how PacBio HiFi sequencing is transforming clinical and translational research. Catch live Vega demos and discover the power of complete, accurate data.

Full program: bit.ly/47Ubb6y

#PacBio #AMPath2025 #HiFisequencing
November 13, 2025 at 5:26 PM
We asked researchers at #ASHG25: Short reads or long reads?

The debate lives on, but HiFi sequencing keeps it exciting.

When sequencing sparks debate, #TheresHiFiForThat

Learn more with our Seq101 guide: bit.ly/4gGkp9t

#PacBio
November 12, 2025 at 8:36 PM
October’s Powered by PacBio highlights discoveries from the All of Us Research Program, Fragile X–associated syndromes, cancer studies, ALS research, and more, showcasing how long-read sequencing drives breakthroughs across biology.

Catch up here: bit.ly/49QpbQ7

#PacBio
Powered by PacBio: Selected publications from October 2025 - PacBio
See how researchers are using PacBio technology gain insights across population genomics, cancer research, neurodegenerative disease, and precision medicine.
https://bit.ly/49QpbQ7"
November 12, 2025 at 4:43 PM
@epicypher.bsky.social's is new Fiber-seq Kit works with PacBio long-read sequencing to reveal chromatin accessibility, DNA methylation, and protein footprints on single molecules, expanding access to powerful multiomic analysis.

Learn more: bit.ly/4qSMa3d
Fiber-seq is your complete solution for profiling chromatin accessibility, DNA methylation, and protein footprints in ONE multiomic experiment. This kit contains everything you need to get this assay up and running in your lab.

🔗 Try CUTANA™ Fiber-seq: https://www.epicypher.com/products/fiber-seq/
November 12, 2025 at 1:22 AM
Travel budgets tight? Grants stuck in limbo?

Apply for PacBio’s 2026 conference giveaway. Flights, hotel, and registration (up to $3K) covered

5 winners. Real connections.

Apply now: bit.ly/4oJQxvy
November 11, 2025 at 4:43 PM
Exciting to see our partners at The University of Queensland driving innovative research to turn plant waste into sustainable jet fuel. Proud that PacBio technology is supporting efforts to build a bio-based economy in Australia.

👉 Learn more: bit.ly/3WIsfpS

#PacBio #Sustainability #PlantScience
Finding efficiencies in creating jet fuel from plant waste. A ewly opened ARC Research Hub at #UQ is focused on not only creating jet fuel from plant biomass, but also ensuring it's cost-effective and sustainable. Details via the link:

https://bit.ly/3WIsfpS
November 10, 2025 at 7:01 PM
See how full-length RNA isoform sequencing using #HiFisequencing helps identify novel isoforms, refine ASO design, and advance RNA-targeting drug development. Gain complete isoform resolution.

Access the brief: bit.ly/4qK9MqN

#PacBio
November 10, 2025 at 6:38 PM