Abhishek Garg LAB
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abhishekgarglab.bsky.social
Abhishek Garg LAB
@abhishekgarglab.bsky.social
170 followers 170 following 130 posts
Cell Stress & Immunity (CSI) Lab headed by Prof. Garg uses novel reverse translation powered by #multiomics to solve #Cancer #immunology #immunotherapy mysteries!
Lab: https://abhishek-d-garg.wixsite.com/csi-lab
LinkedIn: https://www.linkedin.com/in/adgarg
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abhishekgarglab.bsky.social
Abhishek Garg LAB @abhishekgarglab.bsky.social · Apr 11
📢Happy to share our @natrevimmunol.bsky.social article; Result of #collaboration with @deadoc80.bsky.social @labliston.bsky.social & K Smith!
📑Read here: rdcu.be/ehm67
🔥Take🏠msg: Time to move away from narrow concept of #exhausted T cells to other #hypofunctional #states! 1/6🧵
@oncodaily.bsky.social
abhishekgarglab.bsky.social
💥 #Cool #Research #Alert

#Spatiotemporal #transcriptomic insights into #ferroptosis and TFRC-linked #immune #interactions in #ischemia-#reperfusion acute #kidney #injury

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...
Spatiotemporal transcriptomic insights into ferroptosis and TFRC-linked immune interactions in ischemia-reperfusion acute kidney injury - Genes & Immunity
Genes & Immunity - Spatiotemporal transcriptomic insights into ferroptosis and TFRC-linked immune interactions in ischemia-reperfusion acute kidney injury
www.nature.com
November 16, 2025 at 10:26 AM
abhishekgarglab.bsky.social
💥👁 #Exciting #research #alert
#Macrophage #retrotransposon expression is associated with #lupus

#genes & #Immunity @springernature.com
www.nature.com/articles/s41...
Macrophage retrotransposon expression is associated with lupus - Genes & Immunity
Genes & Immunity - Macrophage retrotransposon expression is associated with lupus
www.nature.com
November 15, 2025 at 11:23 AM
abhishekgarglab.bsky.social
💥 #YTHDF1 mediates #KLF2/ #VSIG4 axis to regulate #Kupffer #cell #polarization to alleviate #sepsis-induced #liver #injury

#genes & #Immunity @springernature.com
www.nature.com/articles/s41...
YTHDF1 mediates KLF2/VSIG4 axis to regulate Kupffer cell polarization to alleviate sepsis-induced liver injury - Genes & Immunity
Genes & Immunity - YTHDF1 mediates KLF2/VSIG4 axis to regulate Kupffer cell polarization to alleviate sepsis-induced liver injury
www.nature.com
November 15, 2025 at 11:18 AM
abhishekgarglab.bsky.social
🚨 Effects of #nucleic #acid #metabolism on #prognosis and #immune #invasion of triple-negative #breast #cancer

#genes & #Immunity @springernature.com www.nature.com/articles/s41...
Effects of nucleic acid metabolism on prognosis and immune invasion of triple-negative breast cancer - Genes & Immunity
Genes & Immunity - Effects of nucleic acid metabolism on prognosis and immune invasion of triple-negative breast cancer
www.nature.com
November 15, 2025 at 11:15 AM
abhishekgarglab.bsky.social
🚨 #Research #alert
#Hspa8 modulation of #immune #responses mitigates #ischemic #brain #injury

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...
Hspa8 modulation of immune responses mitigates ischemic brain injury - Genes & Immunity
Genes & Immunity - Hspa8 modulation of immune responses mitigates ischemic brain injury
www.nature.com
November 2, 2025 at 2:43 PM
abhishekgarglab.bsky.social
🔥 #Review #alert
#Taxonomic #variation in #immune #response strategies among #primates

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...
Taxonomic variation in immune response strategies among primates - Genes & Immunity
Genes & Immunity - Taxonomic variation in immune response strategies among primates
www.nature.com
October 26, 2025 at 10:50 AM
abhishekgarglab.bsky.social
🔥 #Review #alert
#Computational #neoantigen #prediction for #cancer #immunotherapy

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...
Computational neoantigen prediction for cancer immunotherapy - Genes & Immunity
Genes & Immunity - Computational neoantigen prediction for cancer immunotherapy
www.nature.com
October 26, 2025 at 10:47 AM
abhishekgarglab.bsky.social
⏰#October issue of #Genes & #Immunity is online!
👉Read abt #autism, #viral #infection, #inflammatory #bowel #disease #IBD, #Alzheimer #disease, #interferon #responses, #colorectal #cancer, #periodontitis, #microRNA, #lupus, #thymocyte & #celiac #disease
www.nature.com/gene/volumes...
Genes and Immunity - Volume 26 Issue 5, October 2025
www.nature.com
October 17, 2025 at 1:21 PM
abhishekgarglab.bsky.social
#Abnormal #activation of #platelets and #inflammation in #smoking-induced #rheumatoid #arthritis is alleviated by 3,3′-diindolylmethane

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...
Abnormal activation of platelets and inflammation in smoking-induced rheumatoid arthritis is alleviated by 3,3′-diindolylmethane - Genes & Immunity
Genes & Immunity - Abnormal activation of platelets and inflammation in smoking-induced rheumatoid arthritis is alleviated by 3,3′-diindolylmethane
www.nature.com
October 17, 2025 at 9:24 AM
abhishekgarglab.bsky.social
Post-translational #acylation modulates #immunosuppression and #immunotherapy #efficacy in #hepatocellular #carcinoma
#livercancer
#Genes & #immunity @springernature.com
www.nature.com/articles/s41...
Post-translational acylation modulates immunosuppression and immunotherapy efficacy in hepatocellular carcinoma - Genes & Immunity
Genes & Immunity - Post-translational acylation modulates immunosuppression and immunotherapy efficacy in hepatocellular carcinoma
www.nature.com
October 17, 2025 at 8:58 AM
abhishekgarglab.bsky.social
αCGRP deficiency aggravates #pulmonary #fibrosis by promoting #senescence in #alveolar type 2 #cells

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...
αCGRP deficiency aggravates pulmonary fibrosis by promoting senescence in alveolar type 2 cells - Genes & Immunity
Genes & Immunity - αCGRP deficiency aggravates pulmonary fibrosis by promoting senescence in alveolar type 2 cells
www.nature.com
October 17, 2025 at 8:53 AM
abhishekgarglab.bsky.social
🚨 #JOBALERT
👉We r hiring! R u interested in #cuttingedge #kidneycancer #research aiming fr #highimpact #Immunotherapy w/ real #clinical #impact fr #Kidney #cancer #patients?
🧐Then this #PhD #doctoral position is 4u
👉Apply/spread it!
@kuleuvenuniversity.bsky.social
www.kuleuven.be/personeel/jo...
PhD position on Cancer Immunology & Immunotherapy
PhD position on Cancer Immunology & Immunotherapy
www.kuleuven.be
October 8, 2025 at 6:23 PM
abhishekgarglab.bsky.social
The #epigenomic #landscape of #bronchial #epithelial cells reveals the establishment of #trained #immunity

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...
The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity - Genes & Immunity
Genes & Immunity - The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity
www.nature.com
September 27, 2025 at 5:19 PM
abhishekgarglab.bsky.social
#Dexmedetomidine relieves #LPS-induced #acute #lung #injury by boosting HIF-1a/ACOD1 driven anti-#inflammatory #macrophage #polarization

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...
Dexmedetomidine relieves LPS-induced acute lung injury by boosting HIF-1a/ACOD1 driven anti-inflammatory macrophage polarization - Genes & Immunity
Genes & Immunity - Dexmedetomidine relieves LPS-induced acute lung injury by boosting HIF-1a/ACOD1 driven anti-inflammatory macrophage polarization
www.nature.com
September 27, 2025 at 5:10 PM
abhishekgarglab.bsky.social
💪#Power of #bispecifics in #cancer #patient #treatment?
✴️Anti-#PD1 x #LAG3 #bispecific had similar anti-#tumour #efficacy vs anti-#PD1/anti-#CTLA4 #combo but with better #safety #profile
⏲️Time to move #multispecifics vs #macrophages where #monos failed!
www.nature.com/articles/s41...
Neoadjuvant PD-1 and LAG-3-targeting bispecific antibody and other immune checkpoint inhibitor combinations in resectable melanoma: the randomized phase 1b/2 Morpheus-Melanoma trial - Nature Medicine
In the randomized phase 1b/2 Morpheus-Melanoma trial evaluating various neoadjuvant immune checkpoint inhibitor regimens in patients with resectable stage III melanoma, tobemstomig, an anti-PD-1/anti-LAG-3 bispecific antibody, showed the highest pathologic response rate with a better safety profile than the standard treatment approach of ipilimumab plus nivolumab.
www.nature.com
September 24, 2025 at 5:29 PM
Reposted by Abhishek Garg LAB
phdpeter.bsky.social
@natrevimmunol.nature.com
rdcu.be/eGXJH
September 18, 2025 at 12:29 AM
abhishekgarglab.bsky.social
#TUG1 targeting enhances #anticancer #immunity thereby facilitating #lenvatinib efficacy in #hepatocellular #carcinoma

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...
TUG1 targeting enhances anticancer immunity thereby facilitating lenvatinib efficacy in hepatocellular carcinoma - Genes & Immunity
Genes & Immunity - TUG1 targeting enhances anticancer immunity thereby facilitating lenvatinib efficacy in hepatocellular carcinoma
www.nature.com
September 19, 2025 at 1:03 PM
abhishekgarglab.bsky.social
#Transcriptomics and #eQTLs reveal #inflammatory #heterogeneity in the #duodenal lining in #coeliac #disease

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...
Transcriptomics and eQTLs reveal inflammatory heterogeneity in the duodenal lining in coeliac disease - Genes & Immunity
Genes & Immunity - Transcriptomics and eQTLs reveal inflammatory heterogeneity in the duodenal lining in coeliac disease
www.nature.com
September 12, 2025 at 8:02 PM
abhishekgarglab.bsky.social
#Transcriptional #regulation of #Ligase IV by an #intronic #regulatory #element directs #thymocyte #development

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...
Transcriptional regulation of Ligase IV by an intronic regulatory element directs thymocyte development - Genes & Immunity
Genes & Immunity - Transcriptional regulation of Ligase IV by an intronic regulatory element directs thymocyte development
www.nature.com
September 7, 2025 at 8:00 PM
abhishekgarglab.bsky.social
#Discovery of #core #genes for #systemic #lupus #erythematosus via #genome-wide aggregated #trans-#effects #analysis

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...
Discovery of core genes for systemic lupus erythematosus via genome-wide aggregated trans-effects analysis - Genes & Immunity
Genes & Immunity - Discovery of core genes for systemic lupus erythematosus via genome-wide aggregated trans-effects analysis
www.nature.com
September 7, 2025 at 7:55 PM
abhishekgarglab.bsky.social
#IRF3 in #viral #infections: more than just triggering the #interferon #response

#Genes & #immunity @springernature.com
www.nature.com/articles/s41...
IRF3 in viral infections: more than just triggering the interferon response - Genes & Immunity
Genes & Immunity - IRF3 in viral infections: more than just triggering the interferon response
www.nature.com
September 7, 2025 at 7:51 PM
Reposted by Abhishek Garg LAB
IRF3 in viral infections: more than just triggering the interferon response

www.nature.com/articles/s41...
IRF3 in viral infections: more than just triggering the interferon response - Genes & Immunity
Genes & Immunity - IRF3 in viral infections: more than just triggering the interferon response
www.nature.com
September 3, 2025 at 2:04 PM
abhishekgarglab.bsky.social
📌In #September @natrevimmunol.nature.com issue, read our #comprehensive #Review: "The #Diversity of #CD8+ T #cell #dysfunction in #cancer and #viral #infection"

⏩Read: www.nature.com/articles/s41...

🤝Result of fruitful #Collaboration w/ @deadoc80.bsky.social @labliston.bsky.social & Kellie Smith!
August 31, 2025 at 11:49 AM
abhishekgarglab.bsky.social
🙏😇🙏
August 30, 2025 at 11:20 AM
abhishekgarglab.bsky.social
An #efficient #framework to decipher #microRNA #regulatory #programs applied to #Tcells

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...
An efficient framework to decipher microRNA regulatory programs applied to T cells - Genes & Immunity
Genes & Immunity - An efficient framework to decipher microRNA regulatory programs applied to T cells
www.nature.com
August 27, 2025 at 1:00 PM