abrahamlabhms.bsky.social
@abrahamlabhms.bsky.social
Reposted
#NewResearch

Cryo-EM structures of the full-length Junin virus and Machupo virus spike glycoprotein complexes stabilized in the prefusion conformation - analyses reveal features that regulate glycoprotein pH-dependent membrane fusion activity.

#MicroSky 🦠

www.nature.com/articles/s41...
Molecular organization of the New World arenavirus spike glycoprotein complex - Nature Microbiology
Cryo-EM structures of the full-length Junin virus and Machupo virus spike glycoprotein complexes stabilized in the prefusion conformation. Analyses reveal features that regulate glycoprotein pH-depend...
www.nature.com
August 11, 2025 at 2:40 PM
Excited to share our new @natmicrobiol.nature.com paper revealing the most complete arenavirus glycoprotein complex (GPC) structures to date 🤩 www.nature.com/articles/s41...
Molecular organization of the New World arenavirus spike glycoprotein complex - Nature Microbiology
Cryo-EM structures of the full-length Junin virus and Machupo virus spike glycoprotein complexes stabilized in the prefusion conformation. Analyses reveal features that regulate glycoprotein pH-depend...
www.nature.com
August 9, 2025 at 9:51 AM
Reposted
Now online! Molecular basis for shifted receptor recognition by an encephalitic arbovirus
Molecular basis for shifted receptor recognition by an encephalitic arbovirus
Cryo-EM structures and mutational analyses reveal western equine encephalitis virus E2-E1 glycoprotein polymorphisms that determine shifted receptor usage and allow for sequence-based prediction of strain compatibility with human receptors.
dlvr.it
April 5, 2025 at 12:42 PM
Also sharing the terrific news piece by Jake Miller at HMS News on our latest paper! @cp-cell.bsky.social
hms.harvard.edu/news/how-sma...
How A Small Number of Mutations Can Fuel Outbreaks of Western Equine Encephalitis Virus
Study shows how spike protein changes determine the risk of viral outbreaks
hms.harvard.edu
April 4, 2025 at 8:05 PM
Our study on the molecular basis of shifts in receptor recognition by western equine encephalitis virus (WEEV) in the past century, led by Xiaoyi Fan and @wanyuviridae.bsky.social , is online! 👏🎉
www.cell.com/cell/fulltex...
Molecular basis for shifted receptor recognition by an encephalitic arbovirus
Cryo-EM structures and mutational analyses reveal western equine encephalitis virus E2-E1 glycoprotein polymorphisms that determine shifted receptor usage and allow for sequence-based prediction of st...
www.cell.com
April 4, 2025 at 7:59 PM
Excited to share our @biorxivpreprint.bsky.social exploring how binding of western equine encephalitis virus (WEEV) to its cellular receptors evolved over the past century 🤩 www.biorxiv.org/content/10.1... @harvardmicro.bsky.social
January 2, 2025 at 10:25 PM