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Procalcitonin to guide antibiotic use during the first wave of COVID-19 in English and Welsh hospitals: integration and triangulation of findings from quantitative and qualitative sources

Reposted by Adrian Aldcroft

Centre for Trials Research @ctrcardiffuni.bsky.social · Aug 8

🍑 PEACH has landed!

The final publication from the PEACH study is now live in BMJ Open—marking the 8th major output from this impactful research.

🔗 bmjopen.bmj.com/content/15/8...

@researchwales.bsky.social
@ukcrc-ctu.org.uk 📄🎯

Aim To integrate the quantitative and qualitative data collected as part of the PEACH (Procalcitonin: Evaluation of Antibiotic use in COVID-19 Hospitalised patients) study, which evaluated whether pro...

Adrian Aldcroft @ajaldcroft.bsky.social · Jul 21

I'm so glad Leonard is finally receiving the recognition he deserves! Hopefully this helps relieve him of his weighty thoughts. 😂

Adrian Aldcroft @ajaldcroft.bsky.social · Jul 21

He is indeed just sitting in front of his portrait contemplating his existence (also hoping I give him a treat) 😀

Dealing with continuous variables and modelling non-linear associations in healthcare data: practical guide

Adrian Aldcroft @ajaldcroft.bsky.social · Jul 17

Very useful, clearly presented paper published in @bmj.com about dealing with continuous variables. Handy resource for authors and editors www.bmj.com/content/390/...

Proper handling of continuous variables is crucial in healthcare research, for example, within regression modelling for descriptive, explanatory, or predictive purposes. However, inadequate methods ar...

www.bmj.com

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Adrian Aldcroft @ajaldcroft.bsky.social · Jul 14

Wonderful to see this article in BMJ Open having such an impact @sineadmcd89.bsky.social bmjopen.bmj.com/content/15/6...

Adrian Aldcroft @ajaldcroft.bsky.social · Jul 14

Do patients’ and doctors’ perceptions about cardiovascular outcomes coincide?

Answer: No

Highlights the importance of patient involvement in designing research, including identifying key outcomes.

bmjopen.bmj.com/content/15/7...

Reposted by Adrian Aldcroft

Nephrology Journal Club @nephjc.bsky.social · Jul 9

T0a: #NephJC

CKD in T2D isn’t just common - it’s deadly 💣
Up to 1 in 3 people with T2D have CKD, and the risks go way beyond declining eGFR

📈Those with CKD had 2–3x higher rates of CV events, hospitalizations, and death

pubmed.ncbi.nlm.nih....

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Reposted by Adrian Aldcroft

Economics for Health (formerly Tobacconomics) @econforhealth.bsky.social · Jul 9

Congratulations to UBL on a 🆕 #publication in @bmj.com Open 🎉

#Research on youth #smoking in #BiH🇧🇦 finds:
-⬆️#cigarette prices 10% would ⬇️ likelihood of youth smoking initiation 5️⃣%, while
-parental & peer smoking would ⬆️ increase likelihood of initiation.

Learn more👇
bmjopen.bmj.com/content/15/6...

Reposted by Adrian Aldcroft

TROG Cancer Research @trogcancerresearch.bsky.social · Jul 10

Congrats to A/Prof Eric Hau, Dr Sagun Parakh & the CHEST-RT researchers on their new protocol paper in BMJ Open. The study is investigating combining thoracic #RT with chemotherapy & immunotherapy for patients with extensive-stage small-cell lung cancer.
bmjopen.bmj.com/content/15/7...

Reposted by Adrian Aldcroft

Martin Jacobsson @jacobsson.nl · Jul 11

Paper published: Predicting Opportunities for Improvement in Trauma Care using Machine Learning: A retrospective registry-based study at a major trauma centre #MedSky bmjopen.bmj.com/content/15/6...

Reposted by Adrian Aldcroft

Dr Mike Brady (PhD) Consultant Paramedic / Academic @drmikebradyphd.bsky.social · Jul 11

Appropriateness of NHS 111 Wales outcomes—using the Call Prioritisation Streaming System: a RAND/UCLA modified Delphi method

CPSS effectively prioritises and streams patients to appropriate outcomes based on expert clinician consensus.

bmjopen.bmj.com/content/15/7...

Reposted by Adrian Aldcroft

StressLab UniVienna @stresslabvienna.bsky.social · May 12

Our team member Stefanie Hirsch just published her first paper! 🎉

The protocol describes an ecological momentary music intervention for stress reduction in chronically discriminated against Turkish immigrant women.

Curious? Follow this link: doi.org/10.1136/bmjo...

#openaccess

Schematic illustration of the ecological momentary music intervention (EMMI-T). Upon reporting a stressful and/or discriminatory event (E1: ‘pre’), participants will be randomly assigned (50:50) to listen to their study playlist (i.e., intervention event) or not (i.e., control event) (= intervention period). If assigned to an intervention event, participants may choose a music listening duration of 10 or 20 min. A post assessment (E2: ‘post’) will be included to capture effects on subjective stress levels and biological stress markers (salivary cortisol, salivary alpha-amylase).

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Reposted by Adrian Aldcroft

Robert S Miller MD @rsm2800.bsky.social · May 12

Caution that this is a modeling study not a clinical trial, performing annual multi-cancer early detection tests could produce 49% fewer late-stage cancer diagnoses and 21% fewer deaths within 5 yrs compared to usual care bmjopen.bmj.com/content/15/5...

Reposted by Adrian Aldcroft

Lawrence (Larry) Mróz @drmroz.bsky.social · May 12

Developing patient journey maps with Aboriginal and Torres Strait Islander peoples living with dementia or cognitive impairment and their carers: protocol | BMJ Open bmjopen.bmj.com/content/15/5...

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Reposted by Adrian Aldcroft

Eman Zied @ezied.bsky.social · May 12

Hot off the press! Our latest research shows that the availability of community pharmacies has declined in the past decade, with the most deprived areas in England 65% more likely to lose a pharmacy.

In BMJ Open: bmjopen.bmj.com/content/15/5...

#gischat #episky #publichealth #medsky #pharmsky

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Reposted by Adrian Aldcroft

gemashwell.bsky.social @gemashwell.bsky.social · May 2

Is undergraduate medical education contributing to the extreme health inequities faced by socially excluded groups? What do we know and what can we do about it?

Learning about Inclusion Health in undergraduate medical education: a scoping review bmjopen.bmj.com/content/15/4...

National yearly cost of breast cancer screening in the USA and projected cost of advocated guidelines: a simulation study with life table modelling

Reposted by Adrian Aldcroft

Gary Collins @gscollins.bsky.social · Apr 15

NEW PAPER: Updated CONSORT-2025 for reporting randomised trials is now available in the @bmj.com @jama.com , @thelancet.bsky.social, @plos.org and @naturemedicine.bsky.social

—> www.bmj.com/content/389/...

#openscience #transparency #medsky #statssky #episky

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Reposted by Adrian Aldcroft

drlauraesserman.bsky.social @drlauraesserman.bsky.social · Apr 8

This paper is so important and shows how different approaches to screening can change the cost by 20 billion dollars. Being more targeted does just as much good and avoids screening burdens and extra costs for women. bmjopen.bmj.com/content/15/2...

Objective The aim of this study was to estimate the total national direct cost of breast cancer screening from 2019 to 2022 and project the total national cost and average lifetime cost of screening p...

bmjopen.bmj.com/content/15/4...

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Reposted by Adrian Aldcroft

Walter Wittich @walterwittich.bsky.social · Apr 8

Development of the International Classification of Functioning, Disability and Health Core Sets for children and youth with deafblindness: protocol for a multistudy collaboration across regions of WHO

Introduction While the International Classification of Functioning, Disability and Health (ICF) Core Sets have been developed for deafblindness across the lifespan, there are currently no Core Sets sp...

Continuity of care with doctors—a matter of life and death? A systematic review of continuity of care and mortality

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Reposted by Adrian Aldcroft

CarolineJMolloy @carolinejmolloy.bsky.social · Apr 8

The evidence shows that patients of *all ages and levels of health* benefit from continuity of care with the same GP. Wes’s claim that this is only important for older, sicker people is simply not backed up by the evidence bmjopen.bmj.com/content/8/6/...

Objective Continuity of care is a long-standing feature of healthcare, especially of general practice. It is associated with increased patient satisfaction, increased take-up of health promotion, grea...

bmjopen.bmj.com/content/15/3...

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Adrian Aldcroft @ajaldcroft.bsky.social · Apr 2

Physiotherapy and Optimised Enteral Nutrition In the post-acute phase of critical illness (PHOENIX): protocol for a mixed methods feasibility randomised controlled trial

Reposted by Adrian Aldcroft

Dr Alexandra Krendel @alexiconartist.bsky.social · Mar 27

I, alongside Dr Mike Ryder at Lancaster University, have just published an article in BMJ Medical Humanities titled 'Role of science fiction in conceptualising the reproductive future: a linguistic and literary perspective'! It is open access and you can read it here - mh.bmj.com/content/earl... 1/3

mh.bmj.com

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Reposted by Adrian Aldcroft

David McWilliams @david-mcwilliams.bsky.social · Mar 28

The protocol for our PHOENIX trial has been published today, evaluating the feasibility of optimised nutrition and enhanced Physiotherapy for survivors of critical illness #ICURehab bmjopen.bmj.com/content/15/3...

Introduction Each year in the UK, 140 000 patients are discharged from intensive care units (ICUs) to general hospital wards, almost all with complex rehabilitation needs. 84% of patients still requir...

Association between expedited review designations and the US or global burden of disease for drugs approved by the US Food and Drug Administration, 2010–2019: a cross-sectional analysis

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Adrian Aldcroft @ajaldcroft.bsky.social · Mar 31

Do the FDA expedite review for the drugs the world needs the most? Analysis indicates "no". bmjopen.bmj.com/content/14/3... @bentleysciindustry.bsky.social

Objectives Pharmaceutical innovation can contribute to reducing the burden of disease in human populations. This research asks whether products approved by the US Food and Drug Administration (FDA) fr...