Andre Faure
@ajfaure.bsky.social
Co-founder & CTO @alloxbio.bsky.social / deep mutagenesis / open science / degrowth / anti-imperialism / tax the rich / my views / him
🌐 www.allox.bio
🌐 www.allox.bio
As the imperial boot of the US and Israel relentlessly pounds the face of the Palestinian people, the EU looks on in silence. Its inaction displays more than just stupidity and hypocrisy, the EU is complicit in genocide.
www.theguardian.com/commentisfre...
www.theguardian.com/commentisfre...
By failing to sanction Israel, EU leaders are complicit in its crimes. They must act now | Josep Borrell
Europe’s silence has allowed the genocide of Palestinians to continue unchecked – undermining all it stands for, says Josep Borrell, a former EU high representative
www.theguardian.com
August 1, 2025 at 1:31 PM
As the imperial boot of the US and Israel relentlessly pounds the face of the Palestinian people, the EU looks on in silence. Its inaction displays more than just stupidity and hypocrisy, the EU is complicit in genocide.
www.theguardian.com/commentisfre...
www.theguardian.com/commentisfre...
Reposted by Andre Faure
New preprint from the allostery team
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Allosteric and Energetic Remodeling by Protein Domain Extensions
Many functions of proteins are performed by independently folding structural units called domains. The structures of domains are conserved during evolution but they are not identical. For example, the...
www.biorxiv.org
July 31, 2025 at 4:21 PM
New preprint from the allostery team
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Andre Faure
🎲 Our paper on the genetics, energetics, and allostery in proteins with randomized cores and surfaces is out today @science.org!
🧬 By charting a protein’s sequence universe, we could rationalize which versions were kept through evolution – and why many stable ones were not.
🧬 By charting a protein’s sequence universe, we could rationalize which versions were kept through evolution – and why many stable ones were not.
July 25, 2025 at 6:27 AM
🎲 Our paper on the genetics, energetics, and allostery in proteins with randomized cores and surfaces is out today @science.org!
🧬 By charting a protein’s sequence universe, we could rationalize which versions were kept through evolution – and why many stable ones were not.
🧬 By charting a protein’s sequence universe, we could rationalize which versions were kept through evolution – and why many stable ones were not.
“Nothing is less real than realism. Details are confusing. It is only by selection, by elimination, by emphasis, that we get at the real meaning of things.”
— Georgia O'Keeffe
— Georgia O'Keeffe
June 28, 2025 at 1:57 PM
“Nothing is less real than realism. Details are confusing. It is only by selection, by elimination, by emphasis, that we get at the real meaning of things.”
— Georgia O'Keeffe
— Georgia O'Keeffe
Reposted by Andre Faure
On this day in 1954, the United States orchestrated a coup against Jacobo Árbenz, the progressive and democratically-elected leader of Guatemala, because he sought to restore land to small farmers and Indigenous communities that had been dispossessed by US fruit companies.
June 13, 2025 at 10:33 AM
On this day in 1954, the United States orchestrated a coup against Jacobo Árbenz, the progressive and democratically-elected leader of Guatemala, because he sought to restore land to small farmers and Indigenous communities that had been dispossessed by US fruit companies.
Reposted by Andre Faure
Alzheimer’s disease 🧠starts with a molecular domino effect - but what triggers the first piece to fall?
In our new study we cracked open the black box of early protein aggregation, and the findings could reshape how we fight neurodegeneration. 🧵👇
www.science.org/doi/10.1126/...
In our new study we cracked open the black box of early protein aggregation, and the findings could reshape how we fight neurodegeneration. 🧵👇
www.science.org/doi/10.1126/...
Massively parallel genetic perturbation suggests the energetic structure of an amyloid-β transition state
The aggregation rates of >140,000 mutants reveal the energetic structure of an amyloid-β nucleation reaction transition state.
www.science.org
June 12, 2025 at 12:54 PM
Alzheimer’s disease 🧠starts with a molecular domino effect - but what triggers the first piece to fall?
In our new study we cracked open the black box of early protein aggregation, and the findings could reshape how we fight neurodegeneration. 🧵👇
www.science.org/doi/10.1126/...
In our new study we cracked open the black box of early protein aggregation, and the findings could reshape how we fight neurodegeneration. 🧵👇
www.science.org/doi/10.1126/...
“Scientists often study the past as obsessively as historians because few other professions depend so acutely on it. Every experiment is a conversation with a prior experiment, every new theory a refutation of the old.”
— Siddhartha Mukherjee, The Emperor of All Maladies
— Siddhartha Mukherjee, The Emperor of All Maladies
May 13, 2025 at 8:34 PM
“Scientists often study the past as obsessively as historians because few other professions depend so acutely on it. Every experiment is a conversation with a prior experiment, every new theory a refutation of the old.”
— Siddhartha Mukherjee, The Emperor of All Maladies
— Siddhartha Mukherjee, The Emperor of All Maladies
Reposted by Andre Faure
Any traders with inside information that Trump was going to walk back his tariffs — some of them, presumably, Trump family members and cronies — just made a fortune.
It all feels like chaos until you look more closely at who is winning.
It all feels like chaos until you look more closely at who is winning.
April 9, 2025 at 10:23 PM
Any traders with inside information that Trump was going to walk back his tariffs — some of them, presumably, Trump family members and cronies — just made a fortune.
It all feels like chaos until you look more closely at who is winning.
It all feels like chaos until you look more closely at who is winning.
Reposted by Andre Faure
💜Feliz #11F y #DíadelaMujeryNiñaEnLaCiencia💜
El 8-M de las científicas: miles de mujeres se vuelcan para despertar vocaciones en la niñas
Un movimiento imparable ha arrancado con fuerza: es el sigiloso 8-M de las científicas. Mujeres determinadas a enseñar a las chicas que pueden ser profesionales capaces
www.lavanguardia.com
February 11, 2025 at 8:42 AM
💜Feliz #11F y #DíadelaMujeryNiñaEnLaCiencia💜
At ALLOX @alloxbio.bsky.social in Barcelona we now have 3 computational positions available!
📌Structural Bioinformatics Scientist 👉 tinyurl.com/3rs46j4t
📌Platform Bioinformatician 👉 tinyurl.com/nyvazbke
📌Computational Chemist 👉 tinyurl.com/5n6vpem3
Apply or repost to help us spread the word 🙏
📌Structural Bioinformatics Scientist 👉 tinyurl.com/3rs46j4t
📌Platform Bioinformatician 👉 tinyurl.com/nyvazbke
📌Computational Chemist 👉 tinyurl.com/5n6vpem3
Apply or repost to help us spread the word 🙏
January 30, 2025 at 2:43 PM
At ALLOX @alloxbio.bsky.social in Barcelona we now have 3 computational positions available!
📌Structural Bioinformatics Scientist 👉 tinyurl.com/3rs46j4t
📌Platform Bioinformatician 👉 tinyurl.com/nyvazbke
📌Computational Chemist 👉 tinyurl.com/5n6vpem3
Apply or repost to help us spread the word 🙏
📌Structural Bioinformatics Scientist 👉 tinyurl.com/3rs46j4t
📌Platform Bioinformatician 👉 tinyurl.com/nyvazbke
📌Computational Chemist 👉 tinyurl.com/5n6vpem3
Apply or repost to help us spread the word 🙏