American Journal of Kidney Diseases
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American Journal of Kidney Diseases
@ajkd.bsky.social
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AJKD, official journal of @kidney.org, is the leading source of information devoted to clinical nephrology research and practice. AJKD.org | AJKDblog.org | Organizer of #NephMadness @nephmadness.bsky.social
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American Journal of Kidney Diseases @ajkd.bsky.social · Jan 5
The January 2026 issue is available now! Check out the plain-language summaries on what inspired each study, the basic approach taken, what was learned, and why it matters:

bit.ly/4q2QuMj
ajkd.bsky.social
Exercise and Kidney Health: Core Curriculum 2026

bit.ly/3YK6uXv (OPEN ACCESS)
February 5, 2026 at 11:00 PM
ajkd.bsky.social
Changes in Employment Status After Initiation of Peritoneal and In-center Hemodialysis

bit.ly/4pKLXgA
Unadjusted cumulative incidences of loss of employer-sponsored health insurance among patients on in-center hemodialysis and peritoneal dialysis. The incidence curves start at three months after dialysis initiation. Green, red, and blue lines respectively represent patients on peritoneal dialysis, in-center hemodialysis with a fistula, and in-center hemodialysis without a fistula. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; w/, with; w/o, without.
February 5, 2026 at 5:02 PM
ajkd.bsky.social
The February 2026 issue is available now! Check out the plain-language summaries on what inspired each study, the basic approach taken, what was learned, and why it matters:

bit.ly/46yYaOD
February 5, 2026 at 11:00 AM
ajkd.bsky.social
Effects of Empagliflozin on Urine Biomarkers in EMPA-KIDNEY

bit.ly/3WA9uoy (OPEN ACCESS)
February 5, 2026 at 10:00 AM
ajkd.bsky.social
AJKD invites applications for its Editorial Internship Program, which will provide editorial experience to early career researchers interested in education, teaching, or medical editing/writing.

Apply by April 30. Details: bit.ly/3Z64pFG
February 4, 2026 at 11:01 PM
ajkd.bsky.social
MINI REVIEW: A Practical Primer on How to Detect and Treat Depression in CKD

bit.ly/4agFzJU (FREE)
Criteria for the diagnosis of a Major Depressive Disorder (MDD). According to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5), the patient must experience at least 5 of the symptoms depicted over the same 2-week period, and at least one of the symptoms must be either sadness or loss of Interest. Created with BioRender.com.
February 4, 2026 at 11:00 PM
ajkd.bsky.social
An Economic Evaluation of a One-Day Living Kidney Donor Evaluation Process Compared to the Usual Approach

bit.ly/4qeDkuQ
Cost-Effectiveness Plane of One-Day Evaluation Versus Usual Evaluation Process
February 4, 2026 at 5:02 PM
ajkd.bsky.social
Home Dialysis Utilization in Puerto Rico

bit.ly/4p5ZYFH
February 4, 2026 at 11:00 AM
ajkd.bsky.social
Chronic Pain Locations, Characteristics, and Associations With Other Symptoms in Adults Receiving Maintenance Hemodialysis: Findings From the HOPE Consortium Trial

bit.ly/4qOf7wG (OPEN ACCESS)

#Visual Abstract
February 3, 2026 at 11:01 PM
ajkd.bsky.social
Family History of Kidney Failure, APOL-1 Risk Variants, Social Determinants of Health, and Risk of CKD Progression: Findings From the CRIC Study

bit.ly/3NtxtEn
Cumulative Incidence of CKD progression by family history. Numbers less than 11 individuals are suppressed if data are from the USRDS.
February 3, 2026 at 5:01 PM
Reposted by American Journal of Kidney Diseases
gbadegesinlab.bsky.social
It was a pleasure reviewing the @kdigo.org 2025 clin practice guidelines for PD NS for US practice. Thanks @ajkd.bsky.social for asking me to do this with Chia-shi Wang. Highlight, Levamisole not approved for use in Humans in the US!!👍
ajkd.bsky.social American Journal of Kidney Diseases @ajkd.bsky.social · 3d
KDOQI US Commentary on the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children by Chia-shi Wang and Rasheed Gbadegesin

bit.ly/4q9yAqo (FREE)
February 3, 2026 at 4:51 AM
ajkd.bsky.social
Trajectories of Experiences and Health-Related Quality of Life of Informal Caregivers of Home and In-Center Dialysis Patients: A Multicenter Longitudinal Cohort Study

bit.ly/3Mm91Va (OPEN ACCESS)
February 3, 2026 at 11:01 AM
ajkd.bsky.social
EDITORIAL: Chronic Pain in Hemodialysis: Beyond the Biochemical Paradigm

bit.ly/3LgciVy (FREE)
February 3, 2026 at 11:00 AM
ajkd.bsky.social
NEW on #AJKDBlog: AJKD invites applications for its Editorial Internship Program, which will provide editorial experience to early career researchers interested in education, teaching, or medical editing/writing.

bit.ly/3Z64pFG
February 2, 2026 at 11:01 PM
ajkd.bsky.social
In A Few Words poem by Kylie Manuppelli, BS, BA:

bit.ly/4r2KiEs
February 2, 2026 at 5:06 PM
ajkd.bsky.social
KDOQI US Commentary on the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children by Chia-shi Wang and Rasheed Gbadegesin

bit.ly/4q9yAqo (FREE)
February 2, 2026 at 11:00 AM
ajkd.bsky.social
In the Literature by Georgina Gyarmati:

Are Mother Glomeruli in Good or Bad Company?

bit.ly/4tchcUN (FREE)
February 1, 2026 at 11:00 PM
ajkd.bsky.social
#RenalPath Immunotactoid Glomerulopathy

bit.ly/4q8NHAk (FREE)
Immunotactoid glomerulopathy showing membranoproliferative pattern with widespread glomerular basement membrane splitting and mesangial matrix expansion, and an adhesion to Bowman capsule (Jones silver stain).
February 1, 2026 at 5:00 PM
ajkd.bsky.social
AJKD invites applications for its Editorial Internship Program, which will provide editorial experience to early career researchers interested in education, teaching, or medical editing/writing.

Apply by April 30. Details: bit.ly/3Z64pFG
February 1, 2026 at 5:00 PM
ajkd.bsky.social
2025 AJKD Editors' Choice Award winning article: Genetic Characterization of Kidney Failure of Unknown Etiology in Spain: Findings From the GENSEN Study

bit.ly/3WeEZ72

#VisualAbstract
February 1, 2026 at 11:00 AM
ajkd.bsky.social
Health-Related Quality of Life After Living Kidney Donation: A Systematic Review and Meta-Analysis

bit.ly/47SMtCh #OpenAccess
January 31, 2026 at 11:00 PM
ajkd.bsky.social
NEW on #AJKDBlog: AJKD invites applications for its Editorial Internship Program, which will provide editorial experience to early career researchers interested in education, teaching, or medical editing/writing.

bit.ly/3Z64pFG
January 31, 2026 at 5:01 PM
ajkd.bsky.social
A 24-year-old female with history of epilepsy, depression, and CKD presented to the ED for suicidal ideation and was found to have a creatinine of 6.24 mg/dL

How can skin lesions guide the differential diagnosis for the CKD etiology in this patient?

FREE bit.ly/44EZ2jN
Raised bumpy skin.
January 31, 2026 at 11:00 AM
ajkd.bsky.social
In A Few Words essay by Christina Fang, MD: Physician as Patient

bit.ly/3Xm1I1U (FREE)
January 30, 2026 at 11:00 PM
ajkd.bsky.social
Navigating Anemia Therapy in CKD: The Role of Hypoxia-Inducible Factor Activators

bit.ly/3NOciNx (OPEN ACCESS)
Reversible HIF activation by pharmacological HIF-prolyl-hydroxylase inhibition. Schematic overview of hypoxia-inducible factor (HIF) regulation. The oxygen-sensitive HIF-α subunit is continuously synthesized and rapidly degraded under normoxic conditions. Proteasomal degradation of HIF-α is initiated by prolyl hydroxylase domain (PHD) dioxygenases and mediated by the von Hippel-Lindau (VHL)-E3-ubiquitin ligase complex. PHD dioxygenases, PHD1, PHD2 and PHD3 utilize molecular oxygen and 2-oxoglutarate (2OG) as substrates to hydroxylate the oxygen-sensitive HIF-α subunit at specific proline residues (Pro), with PHD2 being the main regulator of HIF activity in most cells.
January 30, 2026 at 5:03 PM