Albert Vilella, PhD.
@albertvilella.bsky.social
42K followers 130K following 2.6K posts
Bioinformatics Scientist / Next Generation Sequencing, Single Cell and Spatial Biology, Next Generation Proteomics, Liquid Biopsy, SynBio, Compute Acceleration in biotech // http://albertvilella.substack.com
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albertvilella.bsky.social
The power efficiency of Nvidia GB200 chips
albertvilella.bsky.social
The who is who in #AI and the big deals
albertvilella.bsky.social
@nicholemather, not on #Bluesky, on the appointment as new Scientific Advisory Board head at the @wellcometrust.bsky.social Genome Campus in Cambridge
albertvilella.bsky.social
@drsamuelbhume, not on #Bluesky, on Another approval for anti-PD1 immunotherapy:

Cemiplimab just got FDA-approved to reduce recurrence of high-risk squamous cell skin cancer (after surgery and radiotherapy)

It was based on these impressive phase 3 data:
albertvilella.bsky.social
1 min of vigorous = 7.8 mins of moderate = 73 minutes of light (CVD risk).
albertvilella.bsky.social
1 minute of vigorous = 9.4 minutes of moderate = 94 minutes of light intensity activities (type 2 diabetes risk)
albertvilella.bsky.social
@estamatakis.bsky.social , not recently active on #Bluesky, on the health value of each minute of different physical activity intensities against 6 health outcomes.
albertvilella.bsky.social
AlphafoldDB updates, now includes MSAs
albertvilella.bsky.social
This jump in price was marked by strong buying interest, as seen in the very high RSI value, which rose above 87 in the afternoon, indicating the stock was heavily bought.
Reposted by Albert Vilella, PhD.
sproullab.bsky.social
Sequencing advice sought:
Anyone have any experience of Element AVITI sequencing for methylation profiling by WGBS or EM-sequencing?
Useful to know what other people's experience is as local facility have one and cheaper than Illumina for short read sequencing.
Please share 🙏
#epigenetics
albertvilella.bsky.social
RIP John Gurdon, Nobel Prize winner and fellow at @magdalenecollege.bsky.social Cambridge. I had the privilege to sit next to him at a formal dinner in college as a plus one of my wife, and I hope to have 1/10 of his sharpness of mind in my 90s as he had.
mrclmb.bsky.social
John Gurdon, former Group Leader and Head of @cellbiol-mrclmb.bsky.social has died.
Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology.
More: www2.mrc-lmb.cam.ac.uk/john-gurdon-...
#LMBNews
Black and white portrait of John Gurdon, 1971
albertvilella.bsky.social
Original from @marcseitz, not on #Bluesky
albertvilella.bsky.social
providing intuitive displays and deep APIs for its use, and the ability to embed into other websites open to all. It truly has democratised this key technology.

This doesn't stand still as this post from Sameer Velankar and team show - more proteins - more data - more insight!
albertvilella.bsky.social
A huge part of this broad reach has been the collaboration between European Bioinformatics Institute | EMBL-EBI and Google DeepMind on AlphaFoldDB - AlphaFold database - running AlphaFold as baseline for all known proteins,
albertvilella.bsky.social
@shanumathew.bsky.social , not active on Bluesky, on the xAI deal with Nvidia