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Alex Guseman @alexguseman.bsky.social · 3d

but the whole point of the apollo program was to work on rocket booster technology for ICBMs.... Did his teacher ever ask what his dad did in the military?

Alex Guseman @alexguseman.bsky.social · 6d

1.) be patient getting started takes time
2.) every time in the 1st 6mo a colleague asks to get coffee do it.
3.) it’s a marathon not a sprint.
4.) you will make mistakes it’s fine
5.) there’s a lot of this we were never trained for.

Alex Guseman @alexguseman.bsky.social · 8d

I know of a lot of high powered magnets in Pittsburgh…. But I didn’t know I could use them to move furniture !!

Pittsburgh Scanner @pgh-scanner.com · 8d

Lawrenceville. 46th Street. Caller says that his neighbors have a high powered magnet and are using it and other dark arts to move his furniture. Happy Halloween season.

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Alex Guseman @alexguseman.bsky.social · 9d

Pretty cool. With help from some friends modified a 3D printer to make a fraction collector. It cost $200$ instead of 1500$ works perfectly.

Alex Guseman @alexguseman.bsky.social · 12d

🐧🐧🐧🌸🌸🌸🐧🐧🐧
Thank you Marc Andre for all the memories!!!! (Picture courtesy of Father in law)

Alex Guseman @alexguseman.bsky.social · 15d

"d0nT w0rRy Gr0k c@n d0 iT"-19 year old doge employee, probably.

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Alex Guseman @alexguseman.bsky.social · 16d

any if they are shutdown past the submission deadline then they could be considered late/ missing the deadline?

Alex Guseman @alexguseman.bsky.social · 16d

WAIT. this is my first time. Do i need to get it submitted BEFORE the government shuts down?

Alex Guseman @alexguseman.bsky.social · 22d

anyone ever have a cytiva column valve confuse upflow and downflow?

Alex Guseman @alexguseman.bsky.social · 24d

fairly sure the answer is yes. but also idk how.

Reposted by Alex Guseman

Emery Usher, Ph.D. 🏳️‍🌈🏳️‍⚧️🧪 @idpemery.bsky.social · 24d

NMRSky! Is there any way to indicate multiple peak assignments for a single spin system (I.e., exchange where two peaks for one amide are visible) in a BMRB deposition? @nmr900.bsky.social

Thanks!

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Alex Guseman @alexguseman.bsky.social · 24d

anyone else seeing insane tarrif charges? 24% more expensive?!?!

Leaflet-specific phospholipid imaging using genetically encoded proximity sensors - Nature Chemical Biology

Reposted by Alex Guseman

Itay Budin @ibudin.bsky.social · 24d

Very excited to share new work out today in @natchembio.nature.com on a new approach - FACES - for selectively imaging of phospholipids and other biomolecules at spatial resolutions down to individual membrane leaflets (1/n) www.nature.com/articles/s41...

An approach combining bioorthogonal chemistry with genetically encoded fluorogen-activating proteins enables subcellular imaging of phospholipids and glycans, as well as the visualization of lipid tra...

www.nature.com

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Alex Guseman @alexguseman.bsky.social · 25d

talk about the most expensive GMO-pork chop!

Alex Guseman @alexguseman.bsky.social · 27d

In addition the "in-cell" spectra look to clean to truely be in-cell. Now i have never done RNA in-cells but As a Pielak PHD and Gronenborn Postdoc who did in-cell NMR in each lab I can comment that these spectra are very suspect to me.

Alex Guseman @alexguseman.bsky.social · 27d

look at these supernatant controls...they saw leakage in their post and just scrolled down in intensity to try to flatten it out. I have NEVER seen an NMR spectrum without resonances look that much like a flat line and then on top if you look at where the deviations from flat correlate with peaks

Alex Guseman @alexguseman.bsky.social · 29d

Me: Ugh i shouldn't have agreed to review this manuscript it does not match the abstract and is going to be a lot of work when i should be writing a grant...

Also me: oooo invitation to review another manuscript that I know is going to be interesting...✅

*sigh* at least this 2nd one will be easy

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Alex Guseman @alexguseman.bsky.social · Aug 29

this is why I'm glad I don't watch/read the local news... as someone whose lab works a bit on dengue i probably should know its in SD lol

Alex Guseman @alexguseman.bsky.social · Aug 29

haha Sorry! tbf i checked to see if you had made it already!

Alex Guseman @alexguseman.bsky.social · Aug 29

word from RFK Jr is that cataracts are due to mitochondrial stress in the eye lens!

Alex Guseman @alexguseman.bsky.social · Aug 26

bravo Juan. keep up the good work!

Alex Guseman @alexguseman.bsky.social · Aug 26

Oh man. And during talks. I had a hype man in the audience for me during my last talk and he left before I got to thank him.