Alicia Kowaltowski
@aliciakowaltowski.bsky.social
1.5K followers 450 following 120 posts
Mitochondrial enthusiast, occasional violinist.
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Reposted by Alicia Kowaltowski
nexojornal.bsky.social
[opinião] “Os saltos que verdadeiramente empurram as fronteiras do conhecimento vêm da ciência ‘fora da caixinha’. E não vejo na IA a capacidade de explorar.” Leia na coluna de Alicia Kowaltowski.
A ciência e a inteligência, artificial versus cerebral
O produto de IA não é horrível, mas bom também não é – carece de personalidade, criatividade ou insights inesperados que fazem um texto, uma pergunta ou uma hipótese de pesquisa interessante
dlvr.it
aliciakowaltowski.bsky.social
Energetic discussions and a lot of fun at USP´s CoMeta Center for Metabolism trainee mixer yesterday.
aliciakowaltowski.bsky.social
I can't believe I'm forced to waste my time denouncing this as complete and total BS.

(But I'm sure he thinks he knows more than an MD/PhD mitochondrial biologist...)
bunnibytz.bsky.social
via @acyn.bsky.social

RFK JR: I’m looking at kids as I walk through the airports today...and I see these kids that are just overburdened with mitochondrial challenges, inflammation—you can tell from their faces, movements, and lack of social connection
aliciakowaltowski.bsky.social
Overall, our findings uncover a novel and exciting role for beta estradiol receptors in regulating lipid and ketone metabolism, both in vivo and in vitro, highlighting their therapeutic potential as a safer alternative to non-selective hormone replacement therapy.
4/4
aliciakowaltowski.bsky.social
Using an in vitro hepatocyte model, we demonstrate that receptor activation increases reliance on fatty acid oxidation under nutrient overload conditions.
3/4
aliciakowaltowski.bsky.social
In this work, we show that metabolic alterations in lipid handling caused by menopause in rats can be reversed through selective activation of beta estradiol receptors—importantly, receptors that are not linked to gynecological cancers.
2/4
aliciakowaltowski.bsky.social
Our newest preprint is out!!
"𝗕𝗲𝘁𝗮 𝗘𝘀𝘁𝗿𝗮𝗱𝗶𝗼𝗹 𝗥𝗲𝗰𝗲𝗽𝘁𝗼𝗿 𝗠𝗼𝗱𝘂𝗹𝗮𝘁𝗲𝘀 𝗟𝗶𝘃𝗲𝗿 𝗟𝗶𝗽𝗶𝗱 𝗮𝗻𝗱 𝗞𝗲𝘁𝗼𝗻𝗲 𝗠𝗲𝘁𝗮𝗯𝗼𝗹𝗶𝘀𝗺"

www.biorxiv.org/content/10.1...

👇1/4
Beta Estradiol Receptor Modulates Liver Lipid and Ketone Metabolism
Non-selective hormone replacement with estradiol improves metabolic homeostasis during menopause. However, this treatment is not recommended for individuals with genetic predisposition to hormone-resp...
www.biorxiv.org
Reposted by Alicia Kowaltowski
nexojornal.bsky.social
[opinião] “A ciência pode trazer avanços incríveis de formas e locais inesperados, desde que possamos trabalhar em redes colaborativas e ter investimentos.” Leia na coluna de Alicia Kowaltowski.
Novos avanços no entendimento da obesidade 
Mais de 15 mil trabalhos científicos sobre a doença foram publicados desde o início de 2025. Pesquisas abordam diferentes aspectos e geram progressos significativos
dlvr.it
aliciakowaltowski.bsky.social
Congratulations, Erin!! Every US-based scientist should have the same courage to tell their stories of how new policies are negatively impacting Science to the general press. This is about making discoveries for better lives, not a partisan battle.

www.universityofcalifornia.edu/news/phd-stu...
Ph.D. student pens heartfelt appeal for research funding, building a student-led campaign for science
Graduate student Erin Morrow is spending her summer break campaigning for the McClintock Letters.
www.universityofcalifornia.edu
Reposted by Alicia Kowaltowski
standupforscience.bsky.social
🌞 It’s Day 10 of #31DaysOfAction: Get outside for Sunshine Sunday! Grab family & friends, hit the beach for a cleanup, soak in the sun, and yes, touch grass for real. Protect nature and your sanity! Join Our Mission: zurl.co/74e0z #StandUpForScience
aliciakowaltowski.bsky.social
MitoLab celebrating its 25th anniversary. May the next 25 years be even more exciting!!
Reposted by Alicia Kowaltowski
prasad.bsky.social
few outcomes, except for 99% of FDA-approved drugs, 174 recipients of 104 Nobel Prizes, training ~30K MDs and ~10K PhDs per year to enter the workforce, and a 34% reduction in age-adjusted cancer deaths since 1990 -- the largest decrease in history
drugmonkey.bsky.social
Now do the Department of Defense budget, Andrew.

“Washington has thrown billions at NIH for decades with little accountability and few measurable outcomes,” HHS spokesperson Andrew Nixon said in a statement to Future Pulse.

www.politico.com/newsletters/...
NIH spending battle’s ripple effect
www.politico.com
Reposted by Alicia Kowaltowski
nexojornal.bsky.social
[opinião] “A ingestão de açúcar em excesso não é desejável. Será que limitar o uso de corantes artificiais em alimentos é interessante?”. Leia na coluna de Alicia Kowaltowski.
Devemos proibir corantes artificiais nos alimentos?
Secretário da Saúde dos EUA anuncia que produtos com substâncias serão banidos no país. Ideia pode confundir correlação com causa
dlvr.it