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Reposted by Andrew Lin

Greg Jefferis @jefferis.bsky.social · 5d

Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....

Male CNS Connectome

A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

www.janelia.org

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Katrin Vogt @katrinvogt.bsky.social · 13d

How is valence computed in the brain? Check out our new preprint about a single cell that integrates excitatory and inhibitory input across modalities according to valence and impacts behavioral decisions. An exciting collaboration across many labs. Enjoy reading!
www.biorxiv.org/content/10.1...

A multisensory, bidirectional, valence encoder guides behavioral decisions

A key function of the brain is to categorize sensory cues as repulsive or attractive and respond accordingly. While we have some understanding of how sensory information is processed in the sensory pe...

www.biorxiv.org

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HaDi MaBouDi @maboudi.bsky.social · Sep 8

NIBAI 2025 Workshop on the Nature of Intelligence was held in Sheffield, bringing together over 70 participants from diverse backgrounds in neuroscience, animal cognition, philosophy, and AI.

Thanks to @asab.org the @sheffielduni.bsky.social, and @devjoni.bsky.social for sponsoring this event.

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Andrew Lin @andrewclin.bsky.social · Sep 7

Congratulations Oliver!

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Reposted by Andrew Lin

Ariel K. Frame @arielframe.bsky.social · Sep 4

First episode is out! I spoke with Professor James Marshall @sheffielduni.bsky.social @opteran.bsky.social about his research on modelling the #brain of #bees and implications for #ai . Take a listen! #neuroscience #sciencecommunication

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Timothy O'Leary @timothyoleary.bsky.social · Sep 6

We all know that correlation doesn't imply causation. So we took some correlations and tested if they were causal. Here's what happened:

www.cell.com/cell-reports...

An optical brain-machine interface reveals a causal role of posterior parietal cortex in goal-directed navigation

Relating neural circuitry to behavior is challenging due to closed loop interactions between neural activity, actions, and sensations. Sorrell et al. present evidence for a causal role of mouse PPC in...

www.cell.com

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Andrew Lin @andrewclin.bsky.social · Sep 1

This was the work of Katie Greenin-Whitehead and Melissa Tan in my lab, with @eyalrozenfeld.bsky.social and @mosheparnas.bsky.social who did the electrophysiology, and Anthony Moreno-Sanchez, Kurtulus Kullu & Jessica Ausborn who did the compartmental model. Thanks for the super collaboration!

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Andrew Lin @andrewclin.bsky.social · Sep 1

Excited to share our latest work - expressing the bacterial sodium channel in fly Kenyon cells surprisingly *decreases* their excitability, thanks partly to decreased endogenous sodium channels. This prevents learning and decreases odor-evoked calcium influx doi.org/10.1113/JP28...

Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells

Abstract figure legend: We tested the effects of expressing the bacterial voltage-gated sodium channel NaChBac in the Kenyon cells of the Drosophila memory centre, the mushroom body. NaChBac expressi...

doi.org

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Reposted by Andrew Lin

Adrien Peyrache @apeyrache.bsky.social · Apr 14

🚨new paper alert
Blind mice use stereo olfaction, comparing smells between nostrils, to maintain a stable sense of direction. Blocking this ability disrupts their internal compass.

Kudos to @kasumbisa.bsky.social! Another cool chapter of the Trenholm-Peyrache collab😉

www.nature.com/articles/s41...

Stereo olfaction underlies stable coding of head direction in blind mice - Nature Communications

Stereo olfaction involves comparing odor differences between the two nostrils. Here, using neuronal recordings and a behavioral test, the authors demonstrate that blind mice use stereo olfaction to fo...

www.nature.com

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Andrew Lin @andrewclin.bsky.social · Mar 9

Congratulations Silke!

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fkne-scholars.bsky.social @fkne-scholars.bsky.social · Feb 17

2024 marked the 10-year anniversary of the FENS-Kavli Network of Excellence. We warmly invite you to explore the 10-Year Report, showcasing its impact on science, mentoring, outreach, advocacy, and personal achievements. @fens.org @kavlifoundation.bsky.social fenskavlinetwork.org/fkne-10-year...

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dion-synapse.bsky.social @dion-synapse.bsky.social · Feb 14

Excited to have this study out today (on my birthday and 'tines day no less!). Here we resolve input-specific mechanisms of homeostatic plasticity! Congrats Jerry, Kaikai, and team! www.science.org/doi/10.1126/...

Distinct input-specific mechanisms enable presynaptic homeostatic plasticity

Input-specific mechanisms that achieve the homeostatic control of synaptic function are resolved using a botulinum neurotoxin.

www.science.org

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Reposted by Andrew Lin

Wanhe Li @xseedling.bsky.social · Feb 6

Dear All, I believe that this thread will become one of my most important contributions to the fly field (I hope I will make other contributions)! Here, I introduce the Soy Milk Machine Fly Food Method, a.k.a., DeepCook!#Drosophila#NewPI

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gtavosanis.bsky.social @gtavosanis.bsky.social · Jan 27

Excited to share our new preprint: How does the fly mushroom body support odour categorisation and discrimination? 🧠✨ Dive into Ivy Chan's @ivychanchiwai.bsky.social findings on how neural circuits enable complex olfactory processing in flies. Check it out here:
www.biorxiv.org/content/10.1...

Odour representations supporting ethology-relevant categorisation and discrimination in the Drosophila mushroom body

Neural representations of sensory stimuli serve multiple distinct purposes, from the rapid recognition of familiar environments, to the precise identification of individual salient cues. In the insect...

www.biorxiv.org

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Richard Benton @bentonlab.bsky.social · Jan 17

New pre-print: an one-stop shop for everything you wanted to know about the fly olfactory system: www.biorxiv.org/content/10.1...

An integrated anatomical, functional and evolutionary view of the Drosophila olfactory system

The Drosophila melanogaster olfactory system is one of the most intensively studied parts of the nervous system in any animal. Composed of ~60 independent olfactory neuron classes, with several associ...

www.biorxiv.org

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Blake Richards @tyrellturing.bsky.social · Jan 15

This article shows that "non-responsive" neurons can still add to the Fisher Info about object location in the midbrain of weakly electric fish:

www.jneurosci.org/content/45/3...

Brings me back to one of my usual bugbears in #neuroscience, i.e. don't judge a cell's function by its tuning curve!

🧪

Nonresponsive Neurons Improve Population Coding of Object Location

Understanding how heterogeneous neural populations represent sensory input to give rise to behavior remains a central problem in systems neuroscience. Here we investigated how midbrain neurons within ...

www.jneurosci.org

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Junior European Drosophila Investigators @fly-jedi.bsky.social · Jan 7

Dear Droso peeps, we re-announce the upcoming JEDI meeting that will take place at Château du Feÿ from June 3rd to 5th in 2025.
You'll find a prelim program flies-jedi.github.io/projects/202...
We're hoping to gather about 45 of more or less young droso PI to reboot the community.
-> Register Now!

Junior European Drosophila Investigators | JEDI meeting 2025

first post COVID19 meeting

flies-jedi.github.io

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Markus Meister @mameister4.bsky.social · Dec 17

The unbearable slowness of being: Humans still clock in at just 10 bits/s. Even after peer review :) Share link: authors.elsevier.com/a/1kHVa3BtfH.... ArXiv: arxiv.org/abs/2408.10234

authors.elsevier.com

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Rory Coleman @rorycoleman.bsky.social · Dec 10

Sharing my new paper again since moving from the other place 🙂 We shed light on some of the most rapidly evolving animal behaviors—those surrounding mating.

A modular circuit coordinates the diversification of courtship strategies - Nature

Peripheral and central circuit adaptations can be flexibly coordinated in Drosophila, and such a modular circuit organization may facilitate the evolution of mate recognition systems by allowing novel...

www.nature.com

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Carlotta Martelli @crltt.bsky.social · Dec 5

There is an open PhD position in our Lab! In collaboration with the lab of @manuperisse.bsky.social we will study how flies evaluate negative experiences based on context. More info here: mrtlllab.uni-mainz.de/we-are-hiring/

We are hiring! - mrtlllab

We are hiring! Are you passionate about neuroscience and eager to understand how the brain processes negative experiences? The mrtllab is looking for a driven PhD candidate to study the neural mechani...

mrtlllab.uni-mainz.de

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Eyal Rozenfeld @eyalrozenfeld.bsky.social · Dec 8

1/ 🧠 Ever wondered how different types of learning coexist in our brains? Spoiler: Sometimes, they don’t! Our new study flips the script on what we thought about memory and learning in Drosophila. Dive in for a surprising twist! 🧵👇
www.science.org/doi/10.1126/...

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mosheparnas.bsky.social @mosheparnas.bsky.social · Dec 8

1/ How do animals integrate different forms of learning? Our
@eyalrozenfeld.bsky.social new study in Science Advances
shows that active mechanisms prevent the co-formation of competing memories. Here’s what we found! 🧵👇
science.org/doi/10.1126/...

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Carolina Rezaval @crezaval.bsky.social · Dec 6

New from Shiko Parnas' lab: Classical & operant learning in *Drosophila* rely on distinct neuronal pathways, challenging current paradigms! Unstoppable

www.science.org/doi/10.1126/...

Neuronal circuit mechanisms of competitive interaction between action-based and coincidence learning

Parallel and interfering neuronal circuits are responsible for operant and classical learning.

www.science.org

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Moita Lab @moitalab.bsky.social · Dec 2

Thrilled to present our latest BioRXiv on brain/body interactions during defensive freezing behaviour! (www.biorxiv.org/content/10.1...). You might think that a frozen animal has, well, frozen muscle activity, right? Wrong! Underneath the still surface of a fly, something in the legs is beating… 🧵

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Katrin Vogt @katrinvogt.bsky.social · Dec 2

I digested two nature papers @natureportfolio.bsky.social @crezaval.bsky.social @MikeCrickmore about flexible integration and decision-making in Drosophila courtship and mating. Out came this dispatch for @currentbiology.bsky.social :
authors.elsevier.com/a/1kCED_LsQS...
Enjoy reading!

authors.elsevier.com

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