aRukon
@arukon0.bsky.social
770 followers
3.1K following
360 posts
Innovative platform optimizing biological sample management in research, promoting animal welfare and reduction. 🌍🔬
🔸 https://arukon.com/
✉️: [email protected]
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aRukon
@arukon0.bsky.social
· Jul 31
Responsible care and use of animals in research at AstraZeneca
We are committed to the discovery and development of the next generation of therapeutics. Animal studies remain essential for this important work. We take the responsibility for the ethical care and u...
www.astrazeneca.com
aRukon
@arukon0.bsky.social
· Jul 22
Transforman la investigación científica con la reutilización de muestras biológicas - Ruvid
Reducir el número de animales en experimentación es un desafío clave en investigación. Para hacer frente a este reto, la Universitat Jaume I de Castelló (UJI) y la empresa Semicrol, S.L. han desarroll...
ruvid.org
aRukon
@arukon0.bsky.social
· Jul 15
Urocanase-Positive Skin-Resident Bacteria Metabolize cis-Urocanic Acid and in Turn Reduce the Immunosuppressive Properties of UVR
The skin microbiome plays an important role in health and disease. We have recently shown that microbes living on the skin regulate the immunomodulatory properties of UVR, but the underlying mechanisms remain to be uncovered. Using a preclinical model of immunosuppression against the chemical allergen 2,4-dinitrofluorobenzene, 16S microbiome sequencing, in vitro cultures, high-performance liquid chromatography-mass spectrometry and the generation of gnotobiotic-like mice, we report that acute UVB radiation induces a transient and significant restructuring of bacterial communities on the skin through one of its major photoproducts, cis-urocanic acid.
www.jidonline.org
aRukon
@arukon0.bsky.social
· Jul 15
The Universitat Jaume I and Semicrol, S.L. transform scientific research with the reuse of biological samples
Reducing the number of animals used in experimentation is a key challenge in research. To address this issue, the Universitat Jaume I in Castelló and the company Semicrol, S.L. have developed a...
www.eurekalert.org