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Amani A. Fawzi et al. from the Feinberg School of Medicine find that baseline nonperfusion and deep capillary plexus ischemia predict two-year retinal nonperfusion progression in diabetic retinopathy.
doi.org/10.1167/iovs.67.1.64
doi.org/10.1167/iovs.67.1.64
January 30, 2026 at 7:13 PM
Amani A. Fawzi et al. from the Feinberg School of Medicine find that baseline nonperfusion and deep capillary plexus ischemia predict two-year retinal nonperfusion progression in diabetic retinopathy.
doi.org/10.1167/iovs.67.1.64
doi.org/10.1167/iovs.67.1.64
Padmanabhan P. Pattabiraman et al. from the Indiana University School of Medicine find that loss of cathepsin K impairs collagen biogenesis and enhances actin polymerization in trabecular meshwork.
doi.org/10.1167/iovs.67.1.63
doi.org/10.1167/iovs.67.1.63
January 30, 2026 at 7:13 PM
Padmanabhan P. Pattabiraman et al. from the Indiana University School of Medicine find that loss of cathepsin K impairs collagen biogenesis and enhances actin polymerization in trabecular meshwork.
doi.org/10.1167/iovs.67.1.63
doi.org/10.1167/iovs.67.1.63
João Pedro Marques from Hospitais da Universidade de Coimbra describe enhancing molecular diagnostic accuracy in genetic eye disorders through a personalized re-evaluation strategy.
doi.org/10.1167/iovs.67.1.62
doi.org/10.1167/iovs.67.1.62
January 30, 2026 at 7:12 PM
João Pedro Marques from Hospitais da Universidade de Coimbra describe enhancing molecular diagnostic accuracy in genetic eye disorders through a personalized re-evaluation strategy.
doi.org/10.1167/iovs.67.1.62
doi.org/10.1167/iovs.67.1.62
Shijie Zheng, Ke Hu et al. from The First Affiliated Hospital of Chongqing Medical University find that vitamin E alleviates oxidative damage and attenuates ferroptosis caused by prolonged contraction of the ciliary muscle by activating ACOT7.
doi.org/10.1167/iovs.67.1.61
doi.org/10.1167/iovs.67.1.61
January 29, 2026 at 1:00 PM
Shijie Zheng, Ke Hu et al. from The First Affiliated Hospital of Chongqing Medical University find that vitamin E alleviates oxidative damage and attenuates ferroptosis caused by prolonged contraction of the ciliary muscle by activating ACOT7.
doi.org/10.1167/iovs.67.1.61
doi.org/10.1167/iovs.67.1.61
Elia J. Duh, Xialin Liu et al. from Wilmer Eye Institute & Zhongshan Ophthalmic Center investigate the association among age and thickness of the retina, RPE, and choriocapillaris in cynomolgus macaques.
doi.org/10.1167/iovs.67.1.60
doi.org/10.1167/iovs.67.1.60
January 29, 2026 at 1:00 PM
Elia J. Duh, Xialin Liu et al. from Wilmer Eye Institute & Zhongshan Ophthalmic Center investigate the association among age and thickness of the retina, RPE, and choriocapillaris in cynomolgus macaques.
doi.org/10.1167/iovs.67.1.60
doi.org/10.1167/iovs.67.1.60
Alexandre Moulin et al. from Jules-Gonin Eye Hospital investigate downregulation of cyclin kinase inhibitors p16INK4a and p27 in conjunctival melanomas.
doi.org/10.1167/iovs.67.1.59
doi.org/10.1167/iovs.67.1.59
January 29, 2026 at 12:59 PM
Alexandre Moulin et al. from Jules-Gonin Eye Hospital investigate downregulation of cyclin kinase inhibitors p16INK4a and p27 in conjunctival melanomas.
doi.org/10.1167/iovs.67.1.59
doi.org/10.1167/iovs.67.1.59
Cynthia Owsley et al. from the University of Alabama at Birmingham investigate preserved contrast sensitivity in early and intermediate age-related macular degeneration and marked loss in late stage.
doi.org/10.1167/iovs.67.1.58
doi.org/10.1167/iovs.67.1.58
January 28, 2026 at 3:57 PM
Cynthia Owsley et al. from the University of Alabama at Birmingham investigate preserved contrast sensitivity in early and intermediate age-related macular degeneration and marked loss in late stage.
doi.org/10.1167/iovs.67.1.58
doi.org/10.1167/iovs.67.1.58
Kun-Che Chang et al from the University of Pittsburgh School of Medicine find that enzymatic disruption of the internal limiting membrane enhances transplanted retinal ganglion cell survival.
doi.org/10.1167/iovs.67.1.57
doi.org/10.1167/iovs.67.1.57
January 28, 2026 at 3:57 PM
Kun-Che Chang et al from the University of Pittsburgh School of Medicine find that enzymatic disruption of the internal limiting membrane enhances transplanted retinal ganglion cell survival.
doi.org/10.1167/iovs.67.1.57
doi.org/10.1167/iovs.67.1.57
Robert M. Lavker, Han Peng, Tsutomu Kume et al. from Northwestern University find that PAX6 deficiency compromises the ability of limbal epithelial stem cells to properly differentiate into mature corneal epithelial cells.
doi.org/10.1167/iovs.67.1.56
doi.org/10.1167/iovs.67.1.56
January 27, 2026 at 5:54 PM
Robert M. Lavker, Han Peng, Tsutomu Kume et al. from Northwestern University find that PAX6 deficiency compromises the ability of limbal epithelial stem cells to properly differentiate into mature corneal epithelial cells.
doi.org/10.1167/iovs.67.1.56
doi.org/10.1167/iovs.67.1.56
Emine Kiliç et al. from Erasmus MC evaluated the feasibility of a multi-marker circulating tumor cell capture approach in uveal melanoma patients at diagnosis, during fractionated stereotactic radiotherapy (fSRT), and at metastatic progression.
doi.org/10.1167/iovs.67.1.55
doi.org/10.1167/iovs.67.1.55
January 27, 2026 at 5:54 PM
Emine Kiliç et al. from Erasmus MC evaluated the feasibility of a multi-marker circulating tumor cell capture approach in uveal melanoma patients at diagnosis, during fractionated stereotactic radiotherapy (fSRT), and at metastatic progression.
doi.org/10.1167/iovs.67.1.55
doi.org/10.1167/iovs.67.1.55
Teresio Avitabile from Azienda Ospedaliero Universitaria Policlinico “G. Rodolico - San Marco” present a longitudinal in vitro assessment of the optical transparency of preserved pre-descemet layers in the absence of corneal endothelium.
doi.org/10.1167/iovs.67.1.54
doi.org/10.1167/iovs.67.1.54
January 23, 2026 at 4:40 PM
Teresio Avitabile from Azienda Ospedaliero Universitaria Policlinico “G. Rodolico - San Marco” present a longitudinal in vitro assessment of the optical transparency of preserved pre-descemet layers in the absence of corneal endothelium.
doi.org/10.1167/iovs.67.1.54
doi.org/10.1167/iovs.67.1.54
Qingjun Zhou, Zongyi Li et al. from Shandong Eye Institute characterize the early transcriptomic and pathologic changes of Fuchs endothelial corneal dystrophy using the Col8a2Q455K/Q455K mutant mouse model.
doi.org/10.1167/iovs.67.1.53
doi.org/10.1167/iovs.67.1.53
January 23, 2026 at 4:39 PM
Qingjun Zhou, Zongyi Li et al. from Shandong Eye Institute characterize the early transcriptomic and pathologic changes of Fuchs endothelial corneal dystrophy using the Col8a2Q455K/Q455K mutant mouse model.
doi.org/10.1167/iovs.67.1.53
doi.org/10.1167/iovs.67.1.53
Meng-Tian Kang, Ningli Wang et al. from Beijing Tongren Eye Center investigate the effects of repeated red laser irradiation at a supraclinical dose on histology and apoptosis-related molecular markers in guinea pig ocular tissues.
doi.org/10.1167/iovs.67.1.52
doi.org/10.1167/iovs.67.1.52
January 23, 2026 at 4:39 PM
Meng-Tian Kang, Ningli Wang et al. from Beijing Tongren Eye Center investigate the effects of repeated red laser irradiation at a supraclinical dose on histology and apoptosis-related molecular markers in guinea pig ocular tissues.
doi.org/10.1167/iovs.67.1.52
doi.org/10.1167/iovs.67.1.52
Antoine P. Brézin et al. from Hôpital Cochin, Université Paris Cité investigate how ERAP1 and ERAP2 genotype combinations influence susceptibility and severity in birdshot chorioretinitis (BSCR), an HLA-A29–associated disease with variable visual outcomes
doi.org/10.1167/iovs.67.1.51
doi.org/10.1167/iovs.67.1.51
January 23, 2026 at 4:39 PM
Antoine P. Brézin et al. from Hôpital Cochin, Université Paris Cité investigate how ERAP1 and ERAP2 genotype combinations influence susceptibility and severity in birdshot chorioretinitis (BSCR), an HLA-A29–associated disease with variable visual outcomes
doi.org/10.1167/iovs.67.1.51
doi.org/10.1167/iovs.67.1.51
Justyn W. Regini et al. from Cardiff University study the structural arrangement of crystallin proteins in the human lens during development.
doi.org/10.1167/iovs.67.1.50
doi.org/10.1167/iovs.67.1.50
January 23, 2026 at 4:38 PM
Justyn W. Regini et al. from Cardiff University study the structural arrangement of crystallin proteins in the human lens during development.
doi.org/10.1167/iovs.67.1.50
doi.org/10.1167/iovs.67.1.50
Valeria Marigo et al. from the University of Modena and Reggio Emilia investigate the modulation of aerobic glycolysis genes during the progression of retinitis pigmentosa.
doi.org/10.1167/iovs.67.1.49
doi.org/10.1167/iovs.67.1.49
January 22, 2026 at 2:57 PM
Valeria Marigo et al. from the University of Modena and Reggio Emilia investigate the modulation of aerobic glycolysis genes during the progression of retinitis pigmentosa.
doi.org/10.1167/iovs.67.1.49
doi.org/10.1167/iovs.67.1.49
Yue Wan et al. from Beijing Tongren Eye Center investigate AAV-DJ–mediated MYOC silencing as a gene therapy approach for myocilin-associated glaucoma.
doi.org/10.1167/iovs.67.1.48
doi.org/10.1167/iovs.67.1.48
January 22, 2026 at 2:57 PM
Yue Wan et al. from Beijing Tongren Eye Center investigate AAV-DJ–mediated MYOC silencing as a gene therapy approach for myocilin-associated glaucoma.
doi.org/10.1167/iovs.67.1.48
doi.org/10.1167/iovs.67.1.48
Kun Liu et al. from Shanghai General Hospital use olink proteomic profiling of vitreous humor and plasma from proliferative diabetic retinopathy patients to identify a novel inflammatory molecular endotype.
doi.org/10.1167/iovs.67.1.47
doi.org/10.1167/iovs.67.1.47
January 21, 2026 at 3:35 PM
Kun Liu et al. from Shanghai General Hospital use olink proteomic profiling of vitreous humor and plasma from proliferative diabetic retinopathy patients to identify a novel inflammatory molecular endotype.
doi.org/10.1167/iovs.67.1.47
doi.org/10.1167/iovs.67.1.47
Xuanchu Duan et al. from Changsha Aier Eye Hospital find that digoxin attenuates ocular hypertension and protects trabecular meshwork cells via ferroptosis inhibition.
doi.org/10.1167/iovs.67.1.46
doi.org/10.1167/iovs.67.1.46
January 21, 2026 at 3:34 PM
Xuanchu Duan et al. from Changsha Aier Eye Hospital find that digoxin attenuates ocular hypertension and protects trabecular meshwork cells via ferroptosis inhibition.
doi.org/10.1167/iovs.67.1.46
doi.org/10.1167/iovs.67.1.46
Qingjun Zhou, Qun Wang et al. from Shandong First Medical University investigate the role of sensory neuropeptide calcitonin gene-related peptide (CGRP) in postrefractive surgery dry eye caused by corneal nerve severing in mice.
doi.org/10.1167/iovs.67.1.45
doi.org/10.1167/iovs.67.1.45
January 21, 2026 at 3:34 PM
Qingjun Zhou, Qun Wang et al. from Shandong First Medical University investigate the role of sensory neuropeptide calcitonin gene-related peptide (CGRP) in postrefractive surgery dry eye caused by corneal nerve severing in mice.
doi.org/10.1167/iovs.67.1.45
doi.org/10.1167/iovs.67.1.45
Hauke M. Schadwinkel et al. from the University Medical Center Hamburg-Eppendorf use layer-specific proteomic profiling of the human cornea to reveal insights into structure and biological function.
doi.org/10.1167/iovs.67.1.44
doi.org/10.1167/iovs.67.1.44
January 21, 2026 at 3:34 PM
Hauke M. Schadwinkel et al. from the University Medical Center Hamburg-Eppendorf use layer-specific proteomic profiling of the human cornea to reveal insights into structure and biological function.
doi.org/10.1167/iovs.67.1.44
doi.org/10.1167/iovs.67.1.44
SriniVas R. Sadda et al. from Doheny Eye Institute investigate the association between perforating scleral vessels and choriocapillaris flow deficits in otherwise healthy myopic eyes, and identify predictors of localized flow deficits at PSV entry sites.
doi.org/10.1167/iovs.67.1.43
doi.org/10.1167/iovs.67.1.43
January 20, 2026 at 4:27 PM
SriniVas R. Sadda et al. from Doheny Eye Institute investigate the association between perforating scleral vessels and choriocapillaris flow deficits in otherwise healthy myopic eyes, and identify predictors of localized flow deficits at PSV entry sites.
doi.org/10.1167/iovs.67.1.43
doi.org/10.1167/iovs.67.1.43
Christian Lotz et al. from the Fraunhofer Institute for Silicate Research investigate the effects of a novel dexamethasone hydrogel drug delivery system on cytokine and mucin expression in a three-dimensional in vitro conjunctival inflammation model.
doi.org/10.1167/iovs.67.1.42
doi.org/10.1167/iovs.67.1.42
January 20, 2026 at 4:26 PM
Christian Lotz et al. from the Fraunhofer Institute for Silicate Research investigate the effects of a novel dexamethasone hydrogel drug delivery system on cytokine and mucin expression in a three-dimensional in vitro conjunctival inflammation model.
doi.org/10.1167/iovs.67.1.42
doi.org/10.1167/iovs.67.1.42
Sung Do Cho, Eun Ji Lee & Tae-Woo Kim from Seoul National University College of Medicine investigate microvascular dropout within the lamina cribrosa in myopic eyes with a parapapillary γ-zone and primary open-angle glaucoma.
doi.org/10.1167/iovs.67.1.41
doi.org/10.1167/iovs.67.1.41
January 20, 2026 at 4:26 PM
Sung Do Cho, Eun Ji Lee & Tae-Woo Kim from Seoul National University College of Medicine investigate microvascular dropout within the lamina cribrosa in myopic eyes with a parapapillary γ-zone and primary open-angle glaucoma.
doi.org/10.1167/iovs.67.1.41
doi.org/10.1167/iovs.67.1.41
Yuki Muraoka et al from Kyoto University Graduate School of Medicine investigate outer retinal remodeling at the cellular level after macular hole (MH) surgery using adaptive optics optical coherence tomography.
doi.org/10.1167/iovs.67.1.40
doi.org/10.1167/iovs.67.1.40
January 20, 2026 at 4:26 PM
Yuki Muraoka et al from Kyoto University Graduate School of Medicine investigate outer retinal remodeling at the cellular level after macular hole (MH) surgery using adaptive optics optical coherence tomography.
doi.org/10.1167/iovs.67.1.40
doi.org/10.1167/iovs.67.1.40