@arvoiovs.bsky.social
Yuanbo Liang et al. from Wenzhou Medical University develop a novel rabbit model of angle-closure glaucoma via ciliary block and elevated trans-lens pressure difference.
doi.org/10.1167/iovs.66.14.60
doi.org/10.1167/iovs.66.14.60
November 24, 2025 at 3:46 PM
Yuanbo Liang et al. from Wenzhou Medical University develop a novel rabbit model of angle-closure glaucoma via ciliary block and elevated trans-lens pressure difference.
doi.org/10.1167/iovs.66.14.60
doi.org/10.1167/iovs.66.14.60
Rajiv R. Mohan et al. from the University of Missouri find that epigenetic reprogramming via sodium butyrate induces corneal myofibroblast dedifferentiation in vitro and inhibits fibrosis in vivo.
doi.org/10.1167/iovs.66.14.59
doi.org/10.1167/iovs.66.14.59
November 24, 2025 at 3:46 PM
Rajiv R. Mohan et al. from the University of Missouri find that epigenetic reprogramming via sodium butyrate induces corneal myofibroblast dedifferentiation in vitro and inhibits fibrosis in vivo.
doi.org/10.1167/iovs.66.14.59
doi.org/10.1167/iovs.66.14.59
Xuemin Jin et al. from The First Affiliated Hospital of Zhengzhou University establish preclinical safety data to advance mitochondrial targeted AAV-delivered human ND4 (MTSAAV/hND4) for treatment of Leber Hereditary Optic Neuropathy (LHON).
doi.org/10.1167/iovs.66.14.58
doi.org/10.1167/iovs.66.14.58
November 24, 2025 at 3:45 PM
Xuemin Jin et al. from The First Affiliated Hospital of Zhengzhou University establish preclinical safety data to advance mitochondrial targeted AAV-delivered human ND4 (MTSAAV/hND4) for treatment of Leber Hereditary Optic Neuropathy (LHON).
doi.org/10.1167/iovs.66.14.58
doi.org/10.1167/iovs.66.14.58
David Križaj et al. from the University of Utah School of Medicine find that mechano- and glucocorticoid-sensitive TREK-1 channels regulate conventional outflow and intraocular pressure.
doi.org/10.1167/iovs.66.14.57
doi.org/10.1167/iovs.66.14.57
November 21, 2025 at 5:27 PM
David Križaj et al. from the University of Utah School of Medicine find that mechano- and glucocorticoid-sensitive TREK-1 channels regulate conventional outflow and intraocular pressure.
doi.org/10.1167/iovs.66.14.57
doi.org/10.1167/iovs.66.14.57
New article in the Nystagmus issue bit.ly/48sUcZd by Matt J. Dunnet al. from Cardiff University find that the human fovea Is relatively horizontally elongated in infantile nystagmus.
doi.org/10.1167/iovs.66.14.56
doi.org/10.1167/iovs.66.14.56
November 21, 2025 at 5:26 PM
New article in the Nystagmus issue bit.ly/48sUcZd by Matt J. Dunnet al. from Cardiff University find that the human fovea Is relatively horizontally elongated in infantile nystagmus.
doi.org/10.1167/iovs.66.14.56
doi.org/10.1167/iovs.66.14.56
Giancarlo Iarossi et al. from Bambino Gesù Children's Hospital evaluate the inner retinal changes in patients with ABCA4-related retinal dystrophy (ABCA4-RD), and correlate these changes with the photopic negative response (PhNR).
doi.org/10.1167/iovs.66.14.55
doi.org/10.1167/iovs.66.14.55
November 21, 2025 at 5:24 PM
Giancarlo Iarossi et al. from Bambino Gesù Children's Hospital evaluate the inner retinal changes in patients with ABCA4-related retinal dystrophy (ABCA4-RD), and correlate these changes with the photopic negative response (PhNR).
doi.org/10.1167/iovs.66.14.55
doi.org/10.1167/iovs.66.14.55
Katy C. Liu et al. from Duke University School of Medicine @DukeMedSchool find that intracameral puncture lowers intraocular pressure and triggers an immune response in the conventional outflow tract.
doi.org/10.1167/iovs.66.14.54
doi.org/10.1167/iovs.66.14.54
November 21, 2025 at 5:23 PM
Katy C. Liu et al. from Duke University School of Medicine @DukeMedSchool find that intracameral puncture lowers intraocular pressure and triggers an immune response in the conventional outflow tract.
doi.org/10.1167/iovs.66.14.54
doi.org/10.1167/iovs.66.14.54
Review article by Chi-Ming Chan et al. from Cardinal Tien Hospital discusses the potential of immune checkpoint modulation to revolutionize the management of ocular diseases.
doi.org/10.1167/iovs.66.14.53
doi.org/10.1167/iovs.66.14.53
November 21, 2025 at 5:23 PM
Review article by Chi-Ming Chan et al. from Cardinal Tien Hospital discusses the potential of immune checkpoint modulation to revolutionize the management of ocular diseases.
doi.org/10.1167/iovs.66.14.53
doi.org/10.1167/iovs.66.14.53
Kai Hu, Huayong Zhang et al. from Nanjing University find that inhibition of histone methyltransferase G9a activates autophagy and provides protection in dry eye disease.
doi.org/10.1167/iovs.66.14.52
doi.org/10.1167/iovs.66.14.52
November 20, 2025 at 6:19 PM
Kai Hu, Huayong Zhang et al. from Nanjing University find that inhibition of histone methyltransferase G9a activates autophagy and provides protection in dry eye disease.
doi.org/10.1167/iovs.66.14.52
doi.org/10.1167/iovs.66.14.52
Bingyao Tan et al. from the Singapore Eye Research Institute characterize the three-dimensional morphology of exfoliative material on the anterior lens surface in XFS eyes using ultrahigh-resolution optical coherence tomography.
doi.org/10.1167/iovs.66.14.50
doi.org/10.1167/iovs.66.14.50
November 19, 2025 at 2:57 PM
Bingyao Tan et al. from the Singapore Eye Research Institute characterize the three-dimensional morphology of exfoliative material on the anterior lens surface in XFS eyes using ultrahigh-resolution optical coherence tomography.
doi.org/10.1167/iovs.66.14.50
doi.org/10.1167/iovs.66.14.50
Julie Páleník et al. from Masaryk University reexamine methodological and demographic factors in the pattern glare test.
doi.org/10.1167/iovs.66.14.49
doi.org/10.1167/iovs.66.14.49
November 19, 2025 at 2:57 PM
Julie Páleník et al. from Masaryk University reexamine methodological and demographic factors in the pattern glare test.
doi.org/10.1167/iovs.66.14.49
doi.org/10.1167/iovs.66.14.49
Ann L. Webber et al. from Queensland University of Technology evaluate visual processing and executive function in adults with amblyopia or strabismus under and explore their association with functional capabilities and vision-related quality of life.
doi.org/10.1167/iovs.66.14.48
doi.org/10.1167/iovs.66.14.48
November 19, 2025 at 2:56 PM
Ann L. Webber et al. from Queensland University of Technology evaluate visual processing and executive function in adults with amblyopia or strabismus under and explore their association with functional capabilities and vision-related quality of life.
doi.org/10.1167/iovs.66.14.48
doi.org/10.1167/iovs.66.14.48
Kristen L. Kerber et al. from the New England College of Optometry evaluate longitudinal (3 years) accommodation responses (ARs) in children at high risk (HR) or low risk (LR) for myopia, including a subgroup of children who developed myopia.
doi.org/10.1167/iovs.66.14.47
doi.org/10.1167/iovs.66.14.47
November 19, 2025 at 2:56 PM
Kristen L. Kerber et al. from the New England College of Optometry evaluate longitudinal (3 years) accommodation responses (ARs) in children at high risk (HR) or low risk (LR) for myopia, including a subgroup of children who developed myopia.
doi.org/10.1167/iovs.66.14.47
doi.org/10.1167/iovs.66.14.47
Mark M. G. Walton et al. from the University of Washington find that saccade-related activity in superior colliculus predicts eye choice for goal-directed saccades in monkeys with strabismus.
doi.org/10.1167/iovs.66.14.46
doi.org/10.1167/iovs.66.14.46
November 18, 2025 at 7:08 PM
Mark M. G. Walton et al. from the University of Washington find that saccade-related activity in superior colliculus predicts eye choice for goal-directed saccades in monkeys with strabismus.
doi.org/10.1167/iovs.66.14.46
doi.org/10.1167/iovs.66.14.46
Amani A. Fawzi et al. from the Feinberg School of Medicine evaluate deep capillary plexus ischemia measured on 3 × 3-mm macular optical coherence tomography angiography (OCTA) as a biomarker for referable diabetic retinopathy.
doi.org/10.1167/iovs.66.14.45
doi.org/10.1167/iovs.66.14.45
November 18, 2025 at 7:08 PM
Amani A. Fawzi et al. from the Feinberg School of Medicine evaluate deep capillary plexus ischemia measured on 3 × 3-mm macular optical coherence tomography angiography (OCTA) as a biomarker for referable diabetic retinopathy.
doi.org/10.1167/iovs.66.14.45
doi.org/10.1167/iovs.66.14.45
Lexi Ding et al. from Central South University find that Scutellarin protects retinal ganglion cells in glaucoma by targeting the Hsp90aa1-MAPK pathway to inhibit apoptosis.
doi.org/10.1167/iovs.66.14.44
doi.org/10.1167/iovs.66.14.44
November 18, 2025 at 7:08 PM
Lexi Ding et al. from Central South University find that Scutellarin protects retinal ganglion cells in glaucoma by targeting the Hsp90aa1-MAPK pathway to inhibit apoptosis.
doi.org/10.1167/iovs.66.14.44
doi.org/10.1167/iovs.66.14.44
Xuan Li et al from Tianjin Eye Hospital develop a Seahorse extracellular flux analyzer for real-time monitoring of extracellular acidification rate in mouse corneal punch biopsies, and characterize glycolytic functional changes in corneal injury models.
doi.org/10.1167/iovs.66.14.43
doi.org/10.1167/iovs.66.14.43
November 17, 2025 at 7:43 PM
Xuan Li et al from Tianjin Eye Hospital develop a Seahorse extracellular flux analyzer for real-time monitoring of extracellular acidification rate in mouse corneal punch biopsies, and characterize glycolytic functional changes in corneal injury models.
doi.org/10.1167/iovs.66.14.43
doi.org/10.1167/iovs.66.14.43
Wenbo Zhang et al. from the Ophthalmology and Visual Sciences, University of Texas Medical Branch find that CXCR3 deficiency alleviates retinal ganglion cell loss by regulating neuron–astrocyte communication in a mouse model of glaucoma.
doi.org/10.1167/iovs.66.14.42
doi.org/10.1167/iovs.66.14.42
November 17, 2025 at 7:43 PM
Wenbo Zhang et al. from the Ophthalmology and Visual Sciences, University of Texas Medical Branch find that CXCR3 deficiency alleviates retinal ganglion cell loss by regulating neuron–astrocyte communication in a mouse model of glaucoma.
doi.org/10.1167/iovs.66.14.42
doi.org/10.1167/iovs.66.14.42
Yuling Zou from The Affiliated Eye Hospital, Jiangxi Medical College find that palmitic acid induces ferroptosis in retinal microvascular endothelial cells by palmitoylation of Keap1 to affect diabetic retinopathy.
doi.org/10.1167/iovs.66.14.41
doi.org/10.1167/iovs.66.14.41
November 17, 2025 at 7:43 PM
Yuling Zou from The Affiliated Eye Hospital, Jiangxi Medical College find that palmitic acid induces ferroptosis in retinal microvascular endothelial cells by palmitoylation of Keap1 to affect diabetic retinopathy.
doi.org/10.1167/iovs.66.14.41
doi.org/10.1167/iovs.66.14.41
Yang Cheng et al. from Tongji Medical College find that Mfn2 regulates scleral remodeling in myopia by maintaining endoplasmic reticulum homeostasis in scleral fibroblasts.
doi.org/10.1167/iovs.66.14.40
doi.org/10.1167/iovs.66.14.40
November 17, 2025 at 7:42 PM
Yang Cheng et al. from Tongji Medical College find that Mfn2 regulates scleral remodeling in myopia by maintaining endoplasmic reticulum homeostasis in scleral fibroblasts.
doi.org/10.1167/iovs.66.14.40
doi.org/10.1167/iovs.66.14.40
Marko Gosak et al. from the University of Maribor investigate the mechanisms of calcium (Ca²⁺) wave propagation in the human lens epithelium, focusing on the respective roles of gap-junctional coupling and ATP-mediated paracrine signaling.
doi.org/10.1167/iovs.66.14.39
doi.org/10.1167/iovs.66.14.39
November 17, 2025 at 7:42 PM
Marko Gosak et al. from the University of Maribor investigate the mechanisms of calcium (Ca²⁺) wave propagation in the human lens epithelium, focusing on the respective roles of gap-junctional coupling and ATP-mediated paracrine signaling.
doi.org/10.1167/iovs.66.14.39
doi.org/10.1167/iovs.66.14.39
Zhixi Li et al. from from Zhongshan Ophthalmic Center evaluate the predictive utility of genetic risk for predicting the presence and longitudinal progression of myopic maculopathy among Chinese pediatric and adult high myopia cohorts.
doi.org/10.1167/iovs.66.14.38
doi.org/10.1167/iovs.66.14.38
November 17, 2025 at 7:41 PM
Zhixi Li et al. from from Zhongshan Ophthalmic Center evaluate the predictive utility of genetic risk for predicting the presence and longitudinal progression of myopic maculopathy among Chinese pediatric and adult high myopia cohorts.
doi.org/10.1167/iovs.66.14.38
doi.org/10.1167/iovs.66.14.38
Yang Li et al. from Beijing Tongren Eye Center identify highly invasive subpopulations of tumor cells that may be responsible for early uveal melanoma metastasis at the single-cell level and analyze their interactions with immune cells.
doi.org/10.1167/iovs.66.14.37
doi.org/10.1167/iovs.66.14.37
November 17, 2025 at 7:40 PM
Yang Li et al. from Beijing Tongren Eye Center identify highly invasive subpopulations of tumor cells that may be responsible for early uveal melanoma metastasis at the single-cell level and analyze their interactions with immune cells.
doi.org/10.1167/iovs.66.14.37
doi.org/10.1167/iovs.66.14.37
Ditta Zobor et al. from Semmelweis University Budapest investigate the applicability of electroretinography measurements in congenital PAX6-related aniridia.
doi.org/10.1167/iovs.66.14.36
doi.org/10.1167/iovs.66.14.36
November 14, 2025 at 4:24 PM
Ditta Zobor et al. from Semmelweis University Budapest investigate the applicability of electroretinography measurements in congenital PAX6-related aniridia.
doi.org/10.1167/iovs.66.14.36
doi.org/10.1167/iovs.66.14.36
Georg Ladurner et al. from the Medical University of Vienna report a comparative investigation of the retinal phenotype of three mouse models of Alzheimer's disease with optical coherence tomography.
doi.org/10.1167/iovs.66.14.35
doi.org/10.1167/iovs.66.14.35
November 14, 2025 at 4:22 PM
Georg Ladurner et al. from the Medical University of Vienna report a comparative investigation of the retinal phenotype of three mouse models of Alzheimer's disease with optical coherence tomography.
doi.org/10.1167/iovs.66.14.35
doi.org/10.1167/iovs.66.14.35