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Detoxification of deoxynivalenol by pathogen-inducible tau-class glutathione transferases from wheat

Reposted by American Society for Biochemistry and Molecular Biology

Jason Wong @jwhwong.bsky.social · May 28

Now out at #jbiolchem www.sciencedirect.com/science/arti...

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Reposted by American Society for Biochemistry and Molecular Biology

BioMassSpec @realbiomassspec.bsky.social · Aug 17

Detoxification of deoxynivalenol by pathogen-inducible tau-class glutathione transferases from wheat #JBiolChem #MassSpec www.jbc.org/article/S002...

Deoxynivalenol (DON) is a toxicologically relevant trichothecene mycotoxin frequently found in cereal products. It is a virulence factor produced by the plant pathogen Fusarium graminearum during cere...

Copper acquisition in Bacillus subtilis involves Cu(II) exchange between YcnI and YcnJ

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Reposted by American Society for Biochemistry and Molecular Biology

Ákos T Kovács @evolvedbiofilm.bsky.social · Jul 17

Copper acquisition in Bacillus subtilis involves Cu(II) exchange between YcnI and YcnJ

#JBiolChem from @fisherlab.bsky.social
with @johnhelmann.bsky.social

www.jbc.org/article/S002...

The transition metal copper is biologically essential across all three domains of life. Several copper-dependent proteins and enzymes produced by the Gram-positive bacterium Bacillus subtilis have bee...

MDI Bio Lab’s Elisabeth Marnik Is One of Maine’s “40 Under 40” Leaders

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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 10h

Thank you to everyone who joined our recent committee meeting! #ASBMBJournals #JbiolChem

📸 Committee members here on #Bluesky: @chifungleephd.bsky.social, @marinaholz.bsky.social & @drohsopretty.bsky.social.

American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 10h

Today's #TBT post celebrates 120 years of the Journal of Biological Chemistry! The first issue of JBC was published in Oct. 1905. Here's the ASBMB Membership Committee w/a copy of that first issue! It was a fun moment looking back as the membership committee looks to the future.
asbmb.org/membership

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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 10h

Today's #TBT post celebrates 120 years of the Journal of Biological Chemistry! The first issue of JBC was published in Oct. 1905. Here's the ASBMB Membership Committee w/a copy of that first issue! It was a fun moment looking back as the membership committee looks to the future.
asbmb.org/membership

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Reposted by American Society for Biochemistry and Molecular Biology

MDI Biological Laboratory @mdibiolab.bsky.social · 2d

We are so proud of MDI Bio Lab's Liz Marnik — named one of Maine’s “40 Under 40” by @mainebiz.bsky.social!

Inspiring, leading and making science accessible for all!

🧪 🤝 🍎 👩‍🔬 🧬 #AcademicSky #SciEd #iTeachBio #EduSky
#standwithscience #researchmatters

mdibl.org

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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 1d

Inside JBC | Researchers from @wehi-research.bsky.social engineered Plasmodium vivax diagnostic protein with enhanced yield & stability while preserving antibody-binding, paving the way for more reliable malaria testing.
ow.ly/3asn50X8Orx #InfectiousDiseases #AI #JBiolChem @asbmbjournals.bsky.social

AI-designed biomarker improves malaria diagnostics

Researchers from the University of Melbourne engineered Plasmodium vivax diagnostic protein with enhanced yield and stability while preserving antibody-binding, paving the way for more reliable malari...

Catalytic region mimetics in Na+/H+ exchanger regulatory factor 4 suppress guanylate cyclase 2C activity to regulate enterotoxin triggered diarrhea

American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 1d

JBC: On the cover!
This immunofluorescence image of a mouse intestinal organoid highlights successful peptide delivery (green) targeting NHERF4 sequences that regulate GCC activity in the intestinal epithelium.
➡️More in this paper by Ramananda et al.: ow.ly/7SNT50X6ONZ. #ASBMBJournals

Guanylate cyclase 2C (GCC) upon binding to the bacterial heat-stable enterotoxin ST, generates excessive cGMP, driving intestinal chloride and fluid s…

Rules of engagement: determinants of chemokine receptor activation and selectivity by CCL27 and CCL28

American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 1d

The 2025 #NobelPrize in Physiology or Medicine was awarded to Mary E. Brunkow, Fred Ramsdell & Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

Learn more about their work in this article by Ann Fernholm: ow.ly/MrKf50X8eF6.
🎨Mattias Karlén
#Immunology

Sakaguchi showed that the T cells with CD25 on their surface protect against autoimmune diseases through an experiment in mice that lacked T cells.

The scurfy mutation causes a mutiny in the immune system. Brunkow and Ramsdell succeeded in narrowing down the area of the mutation and locating it in the Foxp3 gene, which turned out to be decisive in the development of regulatory T cells.

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Reposted by American Society for Biochemistry and Molecular Biology

ASBMB Journals @asbmbjournals.bsky.social · 2d

New in JBC press: "Scientists' data illustrate how the modular nature of these chemokines enables their overlapping but non-redundant functions."
Learn more:
www.jbc.org/article/...
#jbiolchem

The distinct functional roles of chemokines CCL27 and CCL28 in epithelial immunity of skin and mucosal tissues, respectively, are coordinated by their shared receptor, CCR10, and the CCL28-specific receptor, CCR3. To identify determinants of receptor activation, internalization and binding specificity, we conducted structure-function studies focused on the N-termini of these two chemokines. Deletion of two N-terminal residues of CCL27 resulted in a CCR10 antagonist, highlighting the critical roles of these residues in driving receptor pharmacology.

Engaging discussions with biological and life sciences professionals about their career journeys and the various opportunities available to graduate students and postdocs.

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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 2d

The 2025 #NobelPrize in Physiology or Medicine was awarded to Mary E. Brunkow, Frederick J. Ramsdell & Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.” Their work shows how the #immunesystem avoids attacking the body’s own tissues.
🎨 Niklas Elmehed
ow.ly/EynG50X8e57

An illustration of Mary E. Brunkow, Frederick J. Ramsdell and Shimon Sakaguchi, who were jointly awarded the 2025 Nobel Prize in Physiology or Medicine “for their discoveries concerning peripheral immune tolerance.” Ill. Niklas Elmehed © Nobel Prize Outreach.

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Reposted by American Society for Biochemistry and Molecular Biology

Soutick Saha, PhD @souticksaha.bsky.social · 2d

I am incredibly grateful to @asbmb.bsky.social and especially @mooneyjoanna.bsky.social for this opportunity. They saw the potential in my work and the value in merging art with biology 🍁🍂🍁

American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 2d

🍂 Cover spotlight!
ASBMB member @souticksaha.bsky.social's (@Wolfram_Alpha) artwork is featured on the fall ASBMB Today cover. It visualizes disorder in 100 human proteins, with hues shifting from green→ yellow→ red, echoing autumn leaves.
➡️Learn more: ow.ly/rJig50X7V5k. #SciArt #SciComm

The cover of the Fall issue of ASBMB Today, created by ASBMB member, Soutick Saha. The cover image features different levels of disorder in 100 human proteins with intrinsically disordered regions from the AlphaFold Protein Structure Database. Disordered regions are highlighted in lighter shades.

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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 2d

🍂 Cover spotlight!
ASBMB member @souticksaha.bsky.social's (@Wolfram_Alpha) artwork is featured on the fall ASBMB Today cover. It visualizes disorder in 100 human proteins, with hues shifting from green→ yellow→ red, echoing autumn leaves.
➡️Learn more: ow.ly/rJig50X7V5k. #SciArt #SciComm

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Reposted by American Society for Biochemistry and Molecular Biology

Chandrima Majumdar @c-majumdar.bsky.social · May 16

Check out the latest episodes of the #ASBMB podcast
Cindy Khuu shares her story of pursuing a career in regulatory affairs
Nisha Cavanaugh, talks about her role in research administration
Shyretha Brown, shares her experience as the director of a non-profit!
www.asbmb.org/career-resou...

In conversation with...

www.asbmb.org

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Reposted by American Society for Biochemistry and Molecular Biology

Cyanotrans @cyanotrans.bsky.social · 9d

A shared basis for nutrient limitation response in cyanobacteria - Journal of Biological Chemistry www.jbc.org/article/S002...

A shared basis for nutrient limitation response in cyanobacteria

Cyanobacteria possess diverse regulatory mechanisms to adapt to nutrient limitation, yet the extent to which these responses are shared across different nutrient stresses remains unclear. Understandin...

Nanotechnology offers a way to restore and re-create coral reef biodiversity.

Reposted by American Society for Biochemistry and Molecular Biology

Soutick Saha, PhD @souticksaha.bsky.social · 2d

𝗠𝘆 𝗳𝗶𝗿𝘀𝘁 𝗰𝗼𝘃𝗲𝗿 𝗽𝗶𝗰!

Very happy to share that my BioArt, From order to disorder, made it to the cover of the ASBMB Today magazine!

Many thanks to @asbmb.bsky.social and @mooneyjoanna.bsky.social for this opportunity.

Cover pic story: www.asbmb.org/asbmb-today/...

#ASBMB #Protein #Art #Disorder

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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 2d

Your discovery could change everything. Present your research alongside other outstanding scientists who are driving #biochemistry & molecular biology forward & making future discoveries and applications possible.

#ASBMB26 abstract submission is now open!
ow.ly/lfWE50X5jVC
#MakeItPossible

Text reads your discovery could change everything. Abstract submission is now open. The background is a scientific image behind a blue, pink and orange gradient.

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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 3d

Did you know HDL isn’t just “good #cholesterol”? Its function — not just levels — can influence #stroke risk. From particle diversity to antioxidant and anti-inflammatory powers, HDL is more complex than you think.
➡️Read the full review in #asbmbJLR: ow.ly/ymIu50X6ORb. #ASBMBJournals #HDL

HDL-mediated RCT in preventing foam cell formation and atherosclerosis.

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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 4d

When Jennifer Matthews first saw corals while learning to scuba dive, she was mesmerized by their neon yellows, pinks and blues.

🪸 “They were so beautiful,” she recalled.

Read more about Matthews’ journey from that moment of wonder to a career studying #coral resilience: ow.ly/vqhZ50X6OHA.

‘Cities under the sea’

Science Outreach and Communication Grant

American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 4d

Get ready to submit your #ASBMB26 abstract!

Discover connections that redefine collaboration, spark breakthroughs that push boundaries & uncover insights that have the power to shape the future of your field.

➡️Abstract submission opens tomorrow: www.asbmb.org/annual....
#MakeItPossible

Text reads abstract submission opens in 1 day! The background is a scientific image behind a blue, pink and orange gradient.

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American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 5d

Are you passionate about making science accessible, engaging & exciting for everyone? Apply for the ASBMB Science Outreach & Communication Grant to bring your vision—podcasts, workshops, community projects—to life.
➡️Applications are due Oct. 31.
ow.ly/mkYl50X6zR2 #SciComm #SciOut

A memberwide grant to encourage new or existing science outreach and communication activities.