ASHE Journal
@ashejournal.bsky.social
Antimicrobial Stewardship & Healthcare Epidemiology, open access journal of the Society for Healthcare Epidemiology of America.
https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology
https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology
Our investigation identified Pseudomonas pseudo-outbreak ("Pseudo-squared"). Recognition of this pseudo-outbreak led to de-escalation of antibiotic therapy and highlighted importance of digital tools, multidisciplinary clinical correlation, and laboratory vigilance. doi.org/10.1017/ash....
Pseudo-squared: Pseudomonas pseudo-outbreak lab investigation | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Pseudo-squared: Pseudomonas pseudo-outbreak lab investigation - Volume 5 Issue 1
doi.org
December 11, 2025 at 9:00 PM
Our investigation identified Pseudomonas pseudo-outbreak ("Pseudo-squared"). Recognition of this pseudo-outbreak led to de-escalation of antibiotic therapy and highlighted importance of digital tools, multidisciplinary clinical correlation, and laboratory vigilance. doi.org/10.1017/ash....
@ryanvpharmd.bsky.social @brainofbpharm.bsky.social: This study evaluated the impact of a guidance document on treatment decisions, clinical outcomes for CRAB, Steno. Our results demonstrate that implementing a treatment guideline may ⬆️ guideline directed treatment. doi.org/10.1017/ash....
Impact of institutional treatment guidance on the management and outcomes of Stenotrophomonas maltophilia and carbapenem-resistant Acinetobacter baumannii infections | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Impact of institutional treatment guidance on the management and outcomes of Stenotrophomonas maltophilia and carbapenem-resistant Acinetobacter baumannii infections - Volume 5 Issue 1
doi.org
December 11, 2025 at 8:00 PM
@ryanvpharmd.bsky.social @brainofbpharm.bsky.social: This study evaluated the impact of a guidance document on treatment decisions, clinical outcomes for CRAB, Steno. Our results demonstrate that implementing a treatment guideline may ⬆️ guideline directed treatment. doi.org/10.1017/ash....
This single-center quality improvement study found that 45% of C. difficile infections were preventable due to inappropriate antibiotic use or treatment of non-guideline conditions. These findings support continued antimicrobial stewardship efforts to reduce CDI rates. doi.org/10.1017/ash....
Low adherence to institutional clinical practice guideline in patients diagnosed with Clostridioides difficile infection | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Low adherence to institutional clinical practice guideline in patients diagnosed with Clostridioides difficile infection - Volume 5 Issue 1
doi.org
December 11, 2025 at 7:00 PM
This single-center quality improvement study found that 45% of C. difficile infections were preventable due to inappropriate antibiotic use or treatment of non-guideline conditions. These findings support continued antimicrobial stewardship efforts to reduce CDI rates. doi.org/10.1017/ash....
One of the few real-world validations of PEN-FAST in hospitalized and clinic patients. In this evaluation of direct oral amoxicillin challenge for low-risk penicillin allergies, 95.7% tolerated the challenge with no immediate or delayed adverse reactions. doi.org/10.1017/ash....
Direct oral amoxicillin challenge in a tertiary care center: validating PEN-FAST in inpatient and outpatient populations with low-risk penicillin allergies | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Direct oral amoxicillin challenge in a tertiary care center: validating PEN-FAST in inpatient and outpatient populations with low-risk penicillin allergies - Volume 5 Issue 1
doi.org
December 11, 2025 at 6:01 PM
One of the few real-world validations of PEN-FAST in hospitalized and clinic patients. In this evaluation of direct oral amoxicillin challenge for low-risk penicillin allergies, 95.7% tolerated the challenge with no immediate or delayed adverse reactions. doi.org/10.1017/ash....
VR Training on Infection Prevention and Control in Long Term Care Facilities shows staff enjoyment and engagement. Head mounted display data highlights VR's potential to enhance competency-based training. doi.org/10.1017/ash....
Playing the long game: virtual reality training for standard precautions in long-term care | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Playing the long game: virtual reality training for standard precautions in long-term care - Volume 5 Issue 1
doi.org
December 11, 2025 at 5:02 PM
VR Training on Infection Prevention and Control in Long Term Care Facilities shows staff enjoyment and engagement. Head mounted display data highlights VR's potential to enhance competency-based training. doi.org/10.1017/ash....
@radhikaarya.bsky.social: The withdrawal of bezlotoxumab leaves a gap in preventing recurrent C diff infection. This commentary reviews current strategies, including PO vancomycin ppx and fecal microbiota-based therapies, and examines their challenges in clinical application. doi.org/10.1017/ash....
Navigating recurrent Clostridioides difficile infection without Bezlotoxumab: potential challenges ahead | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Navigating recurrent Clostridioides difficile infection without Bezlotoxumab: potential challenges ahead - Volume 5 Issue 1
doi.org
December 11, 2025 at 4:01 PM
@radhikaarya.bsky.social: The withdrawal of bezlotoxumab leaves a gap in preventing recurrent C diff infection. This commentary reviews current strategies, including PO vancomycin ppx and fecal microbiota-based therapies, and examines their challenges in clinical application. doi.org/10.1017/ash....
We describe a rapid hospital wide pro-active multidisciplinary safety huddle to prevent CLABSIs in children with high risk lines doi.org/10.1017/ash....
A just-in-time huddle to prevent central line-associated bloodstream infections in high-risk children | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
A just-in-time huddle to prevent central line-associated bloodstream infections in high-risk children - Volume 5 Issue 1
doi.org
December 11, 2025 at 2:38 PM
We describe a rapid hospital wide pro-active multidisciplinary safety huddle to prevent CLABSIs in children with high risk lines doi.org/10.1017/ash....
Bacterial contamination of healthcare workers’ attire 🦠 👩⚕️ doi.org/10.1017/ash....
Bacterial contamination of healthcare workers’ attire | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Bacterial contamination of healthcare workers’ attire - Volume 5 Issue 1
doi.org
December 11, 2025 at 1:00 AM
Bacterial contamination of healthcare workers’ attire 🦠 👩⚕️ doi.org/10.1017/ash....
There are challenges in diagnosis and management of infections among home-based primary care patients doi.org/10.1017/ash....
Evaluating antibiotic prescriptions and standardized surveillance definitions among infections in home-based primary care | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Evaluating antibiotic prescriptions and standardized surveillance definitions among infections in home-based primary care - Volume 5 Issue 1
doi.org
December 10, 2025 at 11:00 PM
There are challenges in diagnosis and management of infections among home-based primary care patients doi.org/10.1017/ash....
In 2022, the Ontario Ministry of Health recommended preoperative nasal mupirocin and chlorhexidine body wash for S aureus decolonization. This 2025 cross-sectional study of 61 hospitals showed heterogeneity in decolonization protocols prior to hip and knee arthroplasty. doi.org/10.1017/ash....
Variation in preoperative self-administered Staphylococcus decolonization protocols for elective knee and hip arthroplasty across hospitals in Ontario, Canada: a cross-sectional study | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Variation in preoperative self-administered Staphylococcus decolonization protocols for elective knee and hip arthroplasty across hospitals in Ontario, Canada: a cross-sectional study - Volume 5…
doi.org
December 10, 2025 at 9:07 PM
In 2022, the Ontario Ministry of Health recommended preoperative nasal mupirocin and chlorhexidine body wash for S aureus decolonization. This 2025 cross-sectional study of 61 hospitals showed heterogeneity in decolonization protocols prior to hip and knee arthroplasty. doi.org/10.1017/ash....
This study shows cefazolin can safely be used as perioperative prophylaxis in patients with cephalosporin allergy labels. This finding is important to endorse and optimize the use of cefazolin as it is associated with better patient outcomes compared to 2nd line antibiotics. doi.org/10.1017/ash....
Cefazolin versus alternative antibiotics for perioperative prophylaxis in patients labeled as cephalosporin allergic | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Cefazolin versus alternative antibiotics for perioperative prophylaxis in patients labeled as cephalosporin allergic - Volume 5 Issue 1
doi.org
December 4, 2025 at 2:38 PM
This study shows cefazolin can safely be used as perioperative prophylaxis in patients with cephalosporin allergy labels. This finding is important to endorse and optimize the use of cefazolin as it is associated with better patient outcomes compared to 2nd line antibiotics. doi.org/10.1017/ash....
Our study implemented a pharmacy-based ASP intervention to decrease time to vancomycin discontinuation using negative MRSA PCR in pneumonia. We measured clinical outcomes using Desirability of Outcome Ranking/Response Adjusted for Duration of Antibiotic Risk (DOOR/RADAR). doi.org/10.1017/ash....
Implementation of an automated methicillin-resistant Staphylococcus aureus polymerase chain reaction screening intervention to guide discontinuation of vancomycin for pneumonia | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Implementation of an automated methicillin-resistant Staphylococcus aureus polymerase chain reaction screening intervention to guide discontinuation of vancomycin for pneumonia - Volume 5 Issue 1
doi.org
December 2, 2025 at 8:30 PM
Our study implemented a pharmacy-based ASP intervention to decrease time to vancomycin discontinuation using negative MRSA PCR in pneumonia. We measured clinical outcomes using Desirability of Outcome Ranking/Response Adjusted for Duration of Antibiotic Risk (DOOR/RADAR). doi.org/10.1017/ash....
We evaluated COVID-19 -related restrictions and their effect on rates of nosocomial respiratory viral infections in pediatric patients undergoing HSCT. Our findings support continuation of the strict isolation practices initially employed during the pandemic for HSCT patients.
December 2, 2025 at 2:38 PM
We evaluated COVID-19 -related restrictions and their effect on rates of nosocomial respiratory viral infections in pediatric patients undergoing HSCT. Our findings support continuation of the strict isolation practices initially employed during the pandemic for HSCT patients.
In a retrospective review of 47 diabetic foot infections, Pseudomonas aeruginosa was isolated in only 10.6% of infections. Despite this, 83% of patients received empiric antibiotic coverage with an antipseudomonal agents. Potential stewardship target? 🤔 doi.org/10.1017/ash....
December 1, 2025 at 8:30 PM
In a retrospective review of 47 diabetic foot infections, Pseudomonas aeruginosa was isolated in only 10.6% of infections. Despite this, 83% of patients received empiric antibiotic coverage with an antipseudomonal agents. Potential stewardship target? 🤔 doi.org/10.1017/ash....
Different large language models (LLMs) demonstrated varying levels of performance in antimicrobial classification tasks. Despite this variability, the results suggest the potential of LLMs to enhance and streamline data analysis processes in antimicrobial stewardship programs doi.org/10.1017/ash....
Evaluation of large language models for antimicrobial classification: implications for antimicrobial stewardship programs | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Evaluation of large language models for antimicrobial classification: implications for antimicrobial stewardship programs - Volume 5 Issue 1
doi.org
December 1, 2025 at 8:15 PM
Different large language models (LLMs) demonstrated varying levels of performance in antimicrobial classification tasks. Despite this variability, the results suggest the potential of LLMs to enhance and streamline data analysis processes in antimicrobial stewardship programs doi.org/10.1017/ash....
This quality improvement project reports on effective and sustainable SSI prevention strategies in a teaching community hospital setting and demonstrated significant improvements in outcome when care processes were regularly monitored and reported on. doi.org/10.1017/ash....
Reduction in abdominal hysterectomy surgical site infections: the impact of monitoring and feedback | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Reduction in abdominal hysterectomy surgical site infections: the impact of monitoring and feedback - Volume 5 Issue 1
doi.org
December 1, 2025 at 5:02 PM
This quality improvement project reports on effective and sustainable SSI prevention strategies in a teaching community hospital setting and demonstrated significant improvements in outcome when care processes were regularly monitored and reported on. doi.org/10.1017/ash....
Our retrospective study of 600 ED patients found that ~10% with negative BacterioScan 216Dx results were unnecessarily treated with antibiotics for suspected UTI. Real-time BacterioScan availability (3-hour turnaround) could reduce inappropriate antibiotic use in ED settings. doi.org/10.1017/ash....
Use of BacterioScan 216Dx to reduce antibiotic use for suspected urinary tract infection in the emergency department | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Use of BacterioScan 216Dx to reduce antibiotic use for suspected urinary tract infection in the emergency department - Volume 5 Issue 1
doi.org
December 1, 2025 at 2:38 PM
Our retrospective study of 600 ED patients found that ~10% with negative BacterioScan 216Dx results were unnecessarily treated with antibiotics for suspected UTI. Real-time BacterioScan availability (3-hour turnaround) could reduce inappropriate antibiotic use in ED settings. doi.org/10.1017/ash....
@tehaili.bsky.social et al: A large Candida auris cohort from Detroit shows high mortality, extended hospital stays, and strong links between infection status, glucose variability, and racial disparities, highlighting key targets for infection prevention and health equity.
December 1, 2025 at 2:19 PM
@tehaili.bsky.social et al: A large Candida auris cohort from Detroit shows high mortality, extended hospital stays, and strong links between infection status, glucose variability, and racial disparities, highlighting key targets for infection prevention and health equity.
Evaluating the clinical and implementation outcomes of continuous antimicrobial stewardship interventions for rapid blood culture diagnostics. doi.org/10.1017/ash....
Clinical and implementation outcomes of an antimicrobial stewardship intervention for rapid blood culture diagnostics | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Clinical and implementation outcomes of an antimicrobial stewardship intervention for rapid blood culture diagnostics - Volume 5 Issue 1
doi.org
December 1, 2025 at 11:16 AM
Evaluating the clinical and implementation outcomes of continuous antimicrobial stewardship interventions for rapid blood culture diagnostics. doi.org/10.1017/ash....
Scoping review of 100 studies (2014–2024) on AI in infection prevention/control. Most used machine learning for prediction/monitoring, but only few integrated in practice. Barriers: data gaps, technical fragility, costs. A 41-item checklist supports safer adoption. doi.org/10.1017/ash....
November 25, 2025 at 8:30 PM
Scoping review of 100 studies (2014–2024) on AI in infection prevention/control. Most used machine learning for prediction/monitoring, but only few integrated in practice. Barriers: data gaps, technical fragility, costs. A 41-item checklist supports safer adoption. doi.org/10.1017/ash....
Antibiotic use among cardiovascular inpatients at Tanzania’s JKCI was 29.9 DDD/100 bed-days, with carbapenems and Reserve agents dominating, highlighting gaps in the stewardship of tertiary cardiac care. doi.org/10.1017/ash....
Trends in antibiotic use among cardiovascular heart disease inpatients at the Jakaya Kikwete Cardiac Institute in Tanzania from 2016 to 2022 | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Trends in antibiotic use among cardiovascular heart disease inpatients at the Jakaya Kikwete Cardiac Institute in Tanzania from 2016 to 2022 - Volume 5 Issue 1
doi.org
November 25, 2025 at 2:38 PM
Antibiotic use among cardiovascular inpatients at Tanzania’s JKCI was 29.9 DDD/100 bed-days, with carbapenems and Reserve agents dominating, highlighting gaps in the stewardship of tertiary cardiac care. doi.org/10.1017/ash....
@caitlinli.bsky.social et al: The use of multiplex PCR panels is rapidly growing despite limited data on optimal use cases - does inclusion of herpesviruses on the meningitis/encephalitis panel hurt or help? doi.org/10.1017/ash....
The clinical impact of herpesvirus testing on multiplex PCR panels in a pediatric population | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
The clinical impact of herpesvirus testing on multiplex PCR panels in a pediatric population - Volume 5 Issue 1
doi.org
November 25, 2025 at 11:15 AM
@caitlinli.bsky.social et al: The use of multiplex PCR panels is rapidly growing despite limited data on optimal use cases - does inclusion of herpesviruses on the meningitis/encephalitis panel hurt or help? doi.org/10.1017/ash....
Infection prevention behaviors and perceptions of nurses in a medical intensive care unit doi.org/10.1017/ash....
Infection prevention behaviors and perceptions of nurses in a medical intensive care unit | Antimicrobial Stewardship & Healthcare Epidemiology | Cambridge Core
Infection prevention behaviors and perceptions of nurses in a medical intensive care unit - Volume 5 Issue 1
doi.org
November 24, 2025 at 8:30 PM
Infection prevention behaviors and perceptions of nurses in a medical intensive care unit doi.org/10.1017/ash....
Impact of switching from polymerase chain reaction-only to two-step Clostridioides difficile testing in a large hospital system doi.org/10.1017/ash....
November 24, 2025 at 2:38 PM
Impact of switching from polymerase chain reaction-only to two-step Clostridioides difficile testing in a large hospital system doi.org/10.1017/ash....
The presence of insects in hospital environments poses a risk for the dissemination of pathogenic bacteria. Despite strict sanitation protocols, some arthropods persist, potentially acting as vectors of bacterial contamination. Read on to find out what we need to do! doi.org/10.1017/ash....
November 24, 2025 at 11:11 AM
The presence of insects in hospital environments poses a risk for the dissemination of pathogenic bacteria. Despite strict sanitation protocols, some arthropods persist, potentially acting as vectors of bacterial contamination. Read on to find out what we need to do! doi.org/10.1017/ash....