aspneph.bsky.social
@aspneph.bsky.social
Circadian blood pressure patterns in kidney transplant recipients assessed by ambulatory blood pressure monitoring
Circadian blood pressure patterns in kidney transplant recipients assessed by ambulatory blood pressure monitoring - Pediatric Nephrology
Background Post-kidney transplant arterial hypertension (HTN) is a very common complication that deteriorates grafts, shortens their lifespan, and involves an increased risk of cardiovascular…
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January 19, 2026 at 4:30 PM
Evaluation of ravulizumab trough levels in pediatric complement-mediated hemolytic uremic syndrome in remission
Evaluation of ravulizumab trough levels in pediatric complement-mediated hemolytic uremic syndrome in remission - Pediatric Nephrology
Background Ravulizumab drug monitoring has not been explored for maintenance therapy in patients with complement-mediated (atypical) hemolytic uremic syndrome (aHUS). Phase III trials suggest the…
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January 19, 2026 at 2:58 PM
Improving hemolytic uremic syndrome diagnosis in children: the role of serology for Shiga toxin-producing Escherichia coli detection
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Improving hemolytic uremic syndrome diagnosis in children: the role of serology for Shiga toxin-producing Escherichia coli detection - Pediatric Nephrology
Background Differentiating STEC-HUS from aHUS can be challenging due to overlapping clinical presentations. Confirming STEC infection is crucial to guide treatment. Although fecal testing is the gold…
link.springer.com
January 19, 2026 at 11:57 AM
Efficacy of mycophenolate mofetil versus cyclophosphamide in the management of childhood-onset lupus nephritis: a systematic review and meta-analysis
#nephsky
Efficacy of mycophenolate mofetil versus cyclophosphamide in the management of childhood-onset lupus nephritis: a systematic review and meta-analysis - Pediatric Nephrology
Background Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), affecting up to one-third of pediatric SLE patients. Timely induction therapy is critical in…
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January 12, 2026 at 11:01 PM
Establishing a reference range for serum creatinine in the neonatal population and re-defining neonatal acute kidney injury
#nephsky
Establishing a reference range for serum creatinine in the neonatal population and re-defining neonatal acute kidney injury - Pediatric Nephrology
Background The current criteria modified from Kidney Disease Improving Global Outcomes (KDIGO) for neonatal AKI (acute kidney injury) underestimate its prevalence. We aim to propose complementary AKI…
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January 12, 2026 at 12:01 PM
Case report: When the kidneys speak for the brain: a nephrological presentation of a rare neurological disorder
#nephsky
When the kidneys speak for the brain: a nephrological presentation of a rare neurological disorder - Pediatric Nephrology
Lesch–Nyhan syndrome (LNS) is a rare X-linked recessive disorder caused by complete deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT). While the disease is classically characterized…
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January 11, 2026 at 10:00 PM
Case report: Cinacalcet therapy in symptomatic 11-year-old girl with familial hypocalciuric hypercalcemia type 3
#nephsky
Cinacalcet therapy in symptomatic 11-year-old girl with familial hypocalciuric hypercalcemia type 3 - Pediatric Nephrology
Abstract Familial hypocalciuric hypercalcemia (FHH) is a rare genetic disorder of calcium regulation. FHH type 3 (FHH3), caused by pathogenic variants in AP2S1, may present with clinically…
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January 11, 2026 at 4:00 PM
Kidney function monitoring in pediatric sickle cell disease: evidence from the NEPHRODREPA study
#nephsky
Kidney function monitoring in pediatric sickle cell disease: evidence from the NEPHRODREPA study - Pediatric Nephrology
Background Sickle cell disease (SCD) induces early kidney abnormalities, beginning in childhood with glomerular hyperfiltration and progressing toward chronic kidney disease. Estimating glomerular…
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January 10, 2026 at 9:00 PM
Review: Gold Standard GFR measurement and GFR estimation in pediatric oncology – indications and limitations @ped_neph
#openaccess
#nephsky
Gold Standard GFR measurement and GFR estimation in pediatric oncology – indications and limitations - Pediatric Nephrology
Knowledge of glomerular filtration rate (GFR) is essential for the treatment and monitoring of children with a malignancy. Ideally, GFR is measured using the gold standard technique of renal inulin…
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January 10, 2026 at 2:01 PM
Association between serum 25-hydroxyvitamin D and #albuminuria in Korean adolescents: evidence from a national survey
#nephsky
Association between serum 25-hydroxyvitamin D and albuminuria in Korean adolescents: evidence from a national survey - Pediatric Nephrology
Objectives Albuminuria is an established early marker of kidney damage and a strong predictor of cardiovascular risk. This study aimed to investigate the association between serum 25-hydroxyvitamin D…
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January 10, 2026 at 12:00 AM
Increased fluid intake and blood pressure in healthy children: a randomized controlled trial. The SPA Project
#RCT
#hypertension
#openaccess
#nephsky
Increased fluid intake and blood pressure in healthy children: a randomized controlled trial. The SPA Project - Pediatric Nephrology
Background High sodium intake is a key element in the development of hypertension, but strategies aimed at reducing its consumption have had limited impact at a population level. A potential…
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January 9, 2026 at 9:00 PM
Influence of intrapatient variability in tacrolimus trough levels on acute rejection in pediatric kidney transplant recipients
#openaccess
#nephsky
Influence of intrapatient variability in tacrolimus trough levels on acute rejection in pediatric kidney transplant recipients - Pediatric Nephrology
Background Tacrolimus is a cornerstone of lifelong immunosuppressive therapy to prevent acute rejection post-kidney transplantation. Tacrolimus intra-patient variability (IPV) is characterized by…
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January 9, 2026 at 5:03 PM
Acute kidney injury in extremely preterm infants: findings from an Australian single-centre retrospective cohort study
#nephsky
#AKI
Acute kidney injury in extremely preterm infants: findings from an Australian single-centre retrospective cohort study - Pediatric Nephrology
Background Neonatal acute kidney injury (AKI) is common in infants born extremely preterm (EPT, < 28 weeks’ gestation). Neonatal AKI is independently associated with increased mortality and is likely…
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January 9, 2026 at 1:01 PM
Prospective observational study of brain magnetic resonance imaging in adolescents with primary #hypertension #nephsky
Prospective observational study of brain magnetic resonance imaging in adolescents with primary hypertension - Pediatric Nephrology
Background Adolescent primary hypertension is associated with decreased neurocognitive performance, a finding suggestive of early target organ damage to the brain. We aimed to determine if adolescent…
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January 8, 2026 at 11:00 PM
Postnatal and long-term outcomes after in utero exposure to RAAS inhibitors: cohort study based on German claims data
#openaccess
#nephsky
Postnatal and long-term outcomes after in utero exposure to RAAS inhibitors: cohort study based on German claims data - Pediatric Nephrology
Background Although use of inhibitors of the renin–angiotensin–aldosterone system (RAAS-I) is contraindicated in the second and third trimesters of pregnancy, a relevant number of pregnancies is…
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January 8, 2026 at 8:00 PM
Immune dysregulation in pediatric cancer–associated nephrotic syndrome: current insights
@Ped_Neph
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December 17, 2025 at 10:30 PM
Re-treatment with rituximab for steroid-dependent nephrotic syndrome in patients with anti-rituximab antibodies
Re-treatment with rituximab for steroid-dependent nephrotic syndrome in patients with anti-rituximab antibodies - Pediatric Nephrology
Pediatric Nephrology -
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December 17, 2025 at 7:31 PM
Optimal selection and timing of steroid-sparing therapy in childhood nephrotic syndrome: what determines long-term outcomes of adult survivors? (review) @Ped_Neph
Optimal selection and timing of steroid-sparing therapy in childhood nephrotic syndrome: what determines long-term outcomes of adult survivors? - Pediatric Nephrology
Pediatric Nephrology -
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December 17, 2025 at 5:30 PM
Immune dysregulation in pediatric cancer–associated nephrotic syndrome: current insights (Review) @Ped_Neph
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Immune dysregulation in pediatric cancer–associated nephrotic syndrome: current insights - Pediatric Nephrology
Nephrotic syndrome (NS) occurring in children with cancer represents a rare yet clinically important paraneoplastic complication. Within pediatric oncology, both primary (idiopathic) and secondary…
link.springer.com
December 17, 2025 at 2:29 PM
Outcomes of Steroid Based Versus Steroid Minimizing Immunosuppression in Pediatric Kidney Transplant Recipients: A NAPRTCS Study
#nephsky
Outcomes of Steroid Based Versus Steroid Minimizing Immunosuppression in Pediatric Kidney Transplant Recipients: A NAPRTCS Study
This study utilizes the NAPRTCS database to compare the allograft function and outcomes (rejection and allograft survival) in pediatric kidney transplant recipients who received steroid based versus…
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December 15, 2025 at 10:02 PM
Reconstruction of single-cell spatial transcriptomes in archival kidney biopsies
#openaccess
#nephsky
Reconstruction of single-cell spatial transcriptomes in archival kidney biopsies
The post-genomic era brought major advancements in biological research, culminating in single-cell RNA sequencing (scRNA-seq) in the late 2010s. However, scRNA-seq requires dissociation of tissues,…
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December 15, 2025 at 6:03 PM
Implementing Patient Navigation for Children with Chronic Kidney Disease
#openaccess
#nephsky
Implementing Patient Navigation for Children with Chronic Kidney Disease
Children with chronic kidney disease (CKD), particularly those who experienced socioeconomic disadvantage, have poorer health and lower quality of life, partly due to limited access to high-quality…
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December 15, 2025 at 12:01 PM