The Asbury Centre
@astburycentre.bsky.social
Understanding Life In Molecular Detail.
An interdisciplinary research centre at @universityofleeds.bsky.social with over 400 researchers who are passionate about understanding life in molecular detail.
https://astbury.leeds.ac.uk/
An interdisciplinary research centre at @universityofleeds.bsky.social with over 400 researchers who are passionate about understanding life in molecular detail.
https://astbury.leeds.ac.uk/
Pinned
👋👋 Hi everyone! The Astbury Centre is now on Bluesky. Follow along for updates about exciting Astbury Centre science. For now, we have put together a starter pack of members of the Astbury Centre community.
Reposted by The Asbury Centre
Research that could change lives: A new paper led by Leeds researchers shows DNA by-products may be 'early warning system' for relapse in childhood leukaemia.
Read it in Nature: bit.ly/41zW927
@cclguk.bsky.social @littleprincesses.bsky.social
@bloodcanceruk.bsky.social @ljrusselllab.bsky.social
Read it in Nature: bit.ly/41zW927
@cclguk.bsky.social @littleprincesses.bsky.social
@bloodcanceruk.bsky.social @ljrusselllab.bsky.social
Excised DNA circles from V(D)J recombination promote relapsed leukaemia
Nature - Excised signal circles are circular DNA by-products of V(D)J recombination that form a complex with the V(D)J recombinase, and when increased in abundance, result in increased mutagenesis,...
bit.ly
August 13, 2025 at 9:15 AM
Research that could change lives: A new paper led by Leeds researchers shows DNA by-products may be 'early warning system' for relapse in childhood leukaemia.
Read it in Nature: bit.ly/41zW927
@cclguk.bsky.social @littleprincesses.bsky.social
@bloodcanceruk.bsky.social @ljrusselllab.bsky.social
Read it in Nature: bit.ly/41zW927
@cclguk.bsky.social @littleprincesses.bsky.social
@bloodcanceruk.bsky.social @ljrusselllab.bsky.social
Reposted by The Asbury Centre
We are proud to share our latest preprint: "(-)-Englerin A binds a conserved lipid site of TRPC5 and exposes a Met-aromatic motif in channel activation".
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
July 13, 2025 at 1:16 PM
We are proud to share our latest preprint: "(-)-Englerin A binds a conserved lipid site of TRPC5 and exposes a Met-aromatic motif in channel activation".
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by The Asbury Centre
An absolute pleasure to host @thornsesholdlab.bsky.social in Leeds today for an amazing @astburycentre.bsky.social seminar.
June 12, 2025 at 4:06 PM
An absolute pleasure to host @thornsesholdlab.bsky.social in Leeds today for an amazing @astburycentre.bsky.social seminar.
Reposted by The Asbury Centre
Swinging lever mechanism of myosin shown by time-resolved cryoEM www.nature.com/articles/s41... so glad to finally be able to share this with the community! @astburycentre.bsky.social @astbury-bsl.bsky.social @stemuench.bsky.social @snmcmillan.bsky.social @davidklebl.bsky.social
Swinging lever mechanism of myosin directly shown by time-resolved cryo-EM - Nature
A study using time-resolved cryogenic electron microscopy reveals the swinging lever mechanism of myosin, providing information on the molecular basis behind the production of force and movement by my...
www.nature.com
April 9, 2025 at 5:19 PM
Swinging lever mechanism of myosin shown by time-resolved cryoEM www.nature.com/articles/s41... so glad to finally be able to share this with the community! @astburycentre.bsky.social @astbury-bsl.bsky.social @stemuench.bsky.social @snmcmillan.bsky.social @davidklebl.bsky.social
Reposted by The Asbury Centre
Excited to report our latest research on new “molecular glues” that specifically lock the BRCC36 isopeptidase complex (BRISC) in an autoinhibited state and reduce interferon signalling. This first-of-its-kind approach could reshape how we target large deubiquitylase (DUB) complexes.
rdcu.be/edRwF
rdcu.be/edRwF
March 17, 2025 at 8:58 PM
Excited to report our latest research on new “molecular glues” that specifically lock the BRCC36 isopeptidase complex (BRISC) in an autoinhibited state and reduce interferon signalling. This first-of-its-kind approach could reshape how we target large deubiquitylase (DUB) complexes.
rdcu.be/edRwF
rdcu.be/edRwF
Congratulations to a team of early-career researchers from the Astbury Centre, on winning "Best disruptive food and drink business plan" at the YES24 competition
astbury.leeds.ac.uk/all_news/win...
astbury.leeds.ac.uk/all_news/win...
Winners of Best disruptive food and drink business plan at the YES24 competition : The Astbury Centre for Structural Molecular Biology
Congratulations to Caffinity Biotech, a team of early-career researchers from the Astbury Centre, on winning "Best disruptive food and drink business plan" sponsored by the Food Consortium Collaborati...
astbury.leeds.ac.uk
February 20, 2025 at 5:00 PM
Congratulations to a team of early-career researchers from the Astbury Centre, on winning "Best disruptive food and drink business plan" at the YES24 competition
astbury.leeds.ac.uk/all_news/win...
astbury.leeds.ac.uk/all_news/win...
Reposted by The Asbury Centre
Are you interested in proteins as exciting, dynamic interacting species. Come and join us- March 28th 2025.
Places are limited so please register ASAP at sheena-radford-lab.uk/fida.php. (£25.00 registration only, including excellent catering).
Places are limited so please register ASAP at sheena-radford-lab.uk/fida.php. (£25.00 registration only, including excellent catering).
January 11, 2025 at 4:25 PM
Are you interested in proteins as exciting, dynamic interacting species. Come and join us- March 28th 2025.
Places are limited so please register ASAP at sheena-radford-lab.uk/fida.php. (£25.00 registration only, including excellent catering).
Places are limited so please register ASAP at sheena-radford-lab.uk/fida.php. (£25.00 registration only, including excellent catering).
👋👋 Hi everyone! The Astbury Centre is now on Bluesky. Follow along for updates about exciting Astbury Centre science. For now, we have put together a starter pack of members of the Astbury Centre community.
January 23, 2025 at 2:37 PM
👋👋 Hi everyone! The Astbury Centre is now on Bluesky. Follow along for updates about exciting Astbury Centre science. For now, we have put together a starter pack of members of the Astbury Centre community.