Adam Charles
@baselesspursuit.bsky.social
250 followers 72 following 35 posts
Computational neuroscience, image processing, data science, and cybernetics. Assistant Professor at Johns Hopkins Biomedical Engineering
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Reposted by Adam Charles
mishaahrens.bsky.social
Preprint -
Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo.
www.biorxiv.org/content/10.1...
Reposted by Adam Charles
carlosbrody.bsky.social
we're crowd-sourcing a searchable repository of tangible benefits stemming from federally-funded research. Come enjoy the great stories; or send in an idea; or volunteer to join the team.

publicusaresearchbenefits.com

please share and re-share so we get more great stories in there!
Searchable database of tangible benefits that federally-funded research gave us.
A crowd-sourced site. Health and Well-being. National Security. Prosperity.
publicusaresearchbenefits.com
Reposted by Adam Charles
justuskebschull.bsky.social
Excited to share the first 2(!) preprints from the Kebschull Lab. The amazing @hyopilkim.bsky.social developed MAPseq2 & POINTseq and used them to map the dopaminergic cells of VTA and SNc. tl;dr MAPseq2=10x cheaper, 4x better; POINTseq=easy cell type specific barcoding; DA neurons=very cool.
Reposted by Adam Charles
biorxiv-neursci.bsky.social
SLAy-ing oversplitting errors in high-density electrophysiology spike sorting https://www.biorxiv.org/content/10.1101/2025.06.20.660590v1
Reposted by Adam Charles
andrewleifer.bsky.social
Join me tomorrow June 11 2-3 ET for an @apsphysics.bsky.social‬ webinar with co-authors Andrea Liu and Sidney Nagel about how scientists can speak up for the rights of scientists, the independence of our institutions and the rule of law. Register here: apsphysics.zoom.us/meeting/regi...
Reposted by Adam Charles
americas-lab.bsky.social
3D printing has a wide variety of applications, from birthday present gimmicks to usage in state-of-the-art science projects, but did you know the technology has its roots in government-funded reseacrh? Read more: publicusaresearchbenefits.com/examples/202...
3D Printing Wasn't Always This Easy
The invention of 3D printing allowing for efficient prototyping
publicusaresearchbenefits.com
Reposted by Adam Charles
americas-lab.bsky.social
Did you know that naloxone, a treatment to reverse opioid overdoses, was originally developed thanks to publicly funded basic research? The National Institute for Drug Abuse figured out how to administer the drug via a nasal spray.

Learn more here: publicusaresearchbenefits.com/examples/202...
Narcan nasal spray for reversing opioid overdose
Narcan nasal spray
publicusaresearchbenefits.com
Reposted by Adam Charles
americas-lab.bsky.social
Before there was Minecraft or Fortnite, there was Tennis for Two, a simple tennis simulation played on an oscilloscope. It was originally designed by William Higinbotham at the publicly funded Brookhaven National Laboratory in 1958.

Learn more here: publicusaresearchbenefits.com/examples/202...
The World's First Video Game: Tennis for Two
the first ever videogame was invented in a lab
publicusaresearchbenefits.com
Reposted by Adam Charles
americas-lab.bsky.social
Did you know closed captioning began as a government funded endeavor? It was originally developed by the National Institute of Standards and Technology to provide more equal access to emergency broadcasts.

Learn more here: publicusaresearchbenefits.com/examples/202...
Federal funding made closed captioning possible
A crowd-sourced site. Health and Well-being. National Security. Prosperity.
publicusaresearchbenefits.com
Reposted by Adam Charles
americas-lab.bsky.social
Wonder what kind of innovations publicly funded science has generated? Look no further than the device you may be reading this post on! Touchscreens started as a NSF funded thesis project at the University of Delaware. Learn more at:

publicusaresearchbenefits.com/examples/202...
Touchscreens
An NSF-funded graduate fellowship changed smartphones all over the world
publicusaresearchbenefits.com
Reposted by Adam Charles
dralexharris.bsky.social
The joy of a new baby can turn into a nightmare when the mom develops postpartum depression. Federally funded research developed a new fast acting medicine to help those moms. publicusaresearchbenefits.com/examples/202... Ask Congress to save science.
#FundingScienceSavesLives
Treatment for postpartum depression
NIH funding for basic research led to new and effective treatment for postpartum depression
publicusaresearchbenefits.com
Reposted by Adam Charles
dralexharris.bsky.social
Do you remember the movie Awakenings? The miracle drug that treated those locked-in patients was L-Dopa, developed with NIH funding, & the gold standard for treating Parkinson’s disease. publicusaresearchbenefits.com/examples/202...

Ask Congress to save science.
#FundingScienceSavesLives
a man with a beard says they need to be reminded of what they have and what they can lose ..
ALT: a man with a beard says they need to be reminded of what they have and what they can lose ..
media.tenor.com
Reposted by Adam Charles
Reposted by Adam Charles
neurograce.bsky.social
TOMORROW 12pm PT/3pm ET, academic workers across the country are organizing to call Senators and Representatives, particularly from historically “red” districts, to sign onto to letters supporting federal research funding. Register here to join the phonebank: form.laborbase.org/251246245216...
Phonebank to Support Federal Research Funding on 5/13
Please click the link to complete this form.
form.laborbase.org
Reposted by Adam Charles
nicolecrust.bsky.social
Calling all science advocates!! Carlos Brody+ are creating a searchable database of tangible science benefits, and they need you.

publicusaresearchbenefits.com

They are asking for suggestions - from brief to lengthy. The database is state-searchable, so all 50 states.

Please spread the word!
Searchable database of tangible benefits that federally-funded research gave us.
A crowd-sourced site. Health and Well-being. National Security. Prosperity.
publicusaresearchbenefits.com
Reposted by Adam Charles
lisamjarvis.bsky.social
In terminating hundreds of NIH grants, the Trump administration dumped years of investment down the drain. In my latest @opinion.bloomberg.com column, we analyzed the cancelled projects & talked to scientists to understand just how much the public loses out. It's a lot: tinyurl.com/bdey86su
A beeswarm chart of canceled NIH grants showing the years into each project when the funding was pulled. Each dot represents a terminated grant and is colored by the number of publications associated with the project: none, one to four or five or more. The grants are separated into thee rows based on the award type (R01, U01, U54). RO1 research projects had the most terminations, which occurred at all stages of research, from the project onset to 7+ years in. Most grants were canceled short of the 4-5 year lifespan of a typical grant, and 40% of R01s had no publications at the time of termination. Projects that had been active for longer had more publications, suggesting that more findings are disseminated in the later stages of these grants.
Reposted by Adam Charles
hopkinsdsai.bsky.social
CREIMBO: Cross-Regional Ensemble Interactions in Multi-view Brain Observations
Noga Mudrik, Ryan Ly, Oliver Ruebel, and Adam S. Charles
arxiv.org/abs/2405.17395
Reposted by Adam Charles
stephaniehicks.bsky.social
Friends, I am at a loss of words for how devastating it would be to lose the entire intramural #NIH program. Some of the biggest medical and scientific breakthroughs have come from scientists in the NIH Intramural program. #SaveTheNIH 🧬🧪 🖥️ 🧠

www.science.org/content/arti...
NIH ban on renewing senior scientists adds to assaults on its in-house research
Policy follows firings of tenure-track scientists and suspension of training programs
www.science.org
Reposted by Adam Charles
danny.hellmo.space
WE JUST GOT DOGE’D

no funding for this year. We have to cancel the program and email 450 applicants there will be no REU program in physics at MSU.

First time in 20+ years.

I’m fucking livid, y’all.
danny.hellmo.space
Ours seems like it might be. We’re in limbo. I wrote my rep about it. 🤞🏽🤞🏽🤞🏽

#physicssky #astrosky
standupforscience.bsky.social
🚨 Many NSF-funded Research Experiences for Undergraduates (REUs) are being cancelled for Summer 2025.

www.reddit.com/r/REU/commen...
baselesspursuit.bsky.social
Today's Haiku
-------------------
The rich man promised
that he would quickly lose weight.
He cut off his limbs.
Reposted by Adam Charles
rhuganir.bsky.social
Reaching out to all Americans through the media to explain how decreasing funding of the NIH will have irreversible harm for developing therapies for all diseases. Please spread the word to your families and friends and contact your congressional representatives.
www.nbcnews.com/science/scie...
Science under siege: Trump cuts threaten to undermine decades of research
Sweeping layoffs, funding freezes and executive orders have provoked outcry among federal researchers and their university partners, who fear that science itself is under siege.
www.nbcnews.com
Reposted by Adam Charles
itaiyanai.bsky.social
We have to stand up for science! Anyone who can join these rallies and believes that US science must be protected should come! @standupforscience.bsky.social