Reposted by Daeyeol Lee
Birds are both intelligent and incredibly agile, yet they are quite small. How do they achieve this with their little brains?
They have twice as many neurons per brain mass than mammals, including primates.
www.pnas.org/doi/abs/10.1...
They have twice as many neurons per brain mass than mammals, including primates.
www.pnas.org/doi/abs/10.1...
November 7, 2025 at 12:55 PM
Birds are both intelligent and incredibly agile, yet they are quite small. How do they achieve this with their little brains?
They have twice as many neurons per brain mass than mammals, including primates.
www.pnas.org/doi/abs/10.1...
They have twice as many neurons per brain mass than mammals, including primates.
www.pnas.org/doi/abs/10.1...
Reposted by Daeyeol Lee
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 24, 2025 at 12:04 PM
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Daeyeol Lee
Thanks to @pessoabrain.bsky.social and @thetransmitter.bsky.social for featuring our paper and to @aliyarumana.bsky.social and Peter Tse for engaging so generously with the ideas! 😊 www.thetransmitter.org/the-big-pict...
Beyond Newtonian causation in neuroscience
The traditional mechanistic framework must give way to a richer understanding of how brains actually generate behavior over time.
www.thetransmitter.org
September 22, 2025 at 6:40 PM
Thanks to @pessoabrain.bsky.social and @thetransmitter.bsky.social for featuring our paper and to @aliyarumana.bsky.social and Peter Tse for engaging so generously with the ideas! 😊 www.thetransmitter.org/the-big-pict...
Reposted by Daeyeol Lee
I am excited to announce that the Johns Hopkins University Solomon H. Snyder Department has become an interdivisional department between the School of Medicine and the Krieger School of Arts and Sciences, unifying neuroscience research and education across the university. hub.jhu.edu/2025/09/15/j...
September 19, 2025 at 2:16 PM
I am excited to announce that the Johns Hopkins University Solomon H. Snyder Department has become an interdivisional department between the School of Medicine and the Krieger School of Arts and Sciences, unifying neuroscience research and education across the university. hub.jhu.edu/2025/09/15/j...
Reposted by Daeyeol Lee
How does the brain decide? 🧠
Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.
After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.
rdcu.be/eGUrv
Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.
After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.
rdcu.be/eGUrv
Transitions in dynamical regime and neural mode during perceptual decisions - Nature
Simultaneous recordings were made of hundreds of neurons in the rat frontal cortex and striatum, showing that decision commitment involves a rapid, coordinated transition in dynamical regime and neura...
www.nature.com
September 17, 2025 at 8:12 PM
How does the brain decide? 🧠
Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.
After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.
rdcu.be/eGUrv
Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.
After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.
rdcu.be/eGUrv
Reposted by Daeyeol Lee
Great to have another paper with @chazfirestone.bsky.social @ianbphillips.bsky.social and the brilliant Hanbei Zhou out! In this paper we demonstrate that stimuli within events are perceived further apart in time — an event-based analog of “object-based warping”. psycnet.apa.org/record/2026-...
September 4, 2025 at 4:27 PM
Great to have another paper with @chazfirestone.bsky.social @ianbphillips.bsky.social and the brilliant Hanbei Zhou out! In this paper we demonstrate that stimuli within events are perceived further apart in time — an event-based analog of “object-based warping”. psycnet.apa.org/record/2026-...
Reposted by Daeyeol Lee
Reposted by Daeyeol Lee
It was an honor to write this, but also great fun. A chance to look back at the classics, and think about the path forward. #Physics is a beautiful human endeavor. journals.aps.org/prxlife/abst...
Emergence of Brains
This review traces how ideas from statistical physics evolved into foundational models of neural computation, shaping modern AI and culminating in the 2024 Nobel Prize in Physics.
journals.aps.org
August 9, 2025 at 2:19 PM
It was an honor to write this, but also great fun. A chance to look back at the classics, and think about the path forward. #Physics is a beautiful human endeavor. journals.aps.org/prxlife/abst...
Reposted by Daeyeol Lee
Neural manifold properties can help us understand how animal brains deal with competing and multifaceted information, execute flexible behaviors and reuse common computations, writes @mattperich.bsky.social.
#neuroskyence
www.thetransmitter.org/neural-dynam...
#neuroskyence
www.thetransmitter.org/neural-dynam...
Neural population-based approaches have opened new windows into neural computations and behavior
Neural manifold properties can help us understand how animal brains deal with complex information, execute flexible behaviors and reuse common computations.
www.thetransmitter.org
August 4, 2025 at 2:56 PM
Neural manifold properties can help us understand how animal brains deal with competing and multifaceted information, execute flexible behaviors and reuse common computations, writes @mattperich.bsky.social.
#neuroskyence
www.thetransmitter.org/neural-dynam...
#neuroskyence
www.thetransmitter.org/neural-dynam...
Reposted by Daeyeol Lee
Poor image quality introduces systematic bias into large neuroimaging datasets, new study of ABCD data shows.
By Natalia Mesa
www.thetransmitter.org/spectrum/poo...
By Natalia Mesa
www.thetransmitter.org/spectrum/poo...
Poor image quality introduces systematic bias into MRI data
Analyses that include low-quality MRI data underestimate cortical thickness and overestimate surface area, according to new work from the ABCD Study.
www.thetransmitter.org
July 31, 2025 at 2:20 PM
Poor image quality introduces systematic bias into large neuroimaging datasets, new study of ABCD data shows.
By Natalia Mesa
www.thetransmitter.org/spectrum/poo...
By Natalia Mesa
www.thetransmitter.org/spectrum/poo...
Reposted by Daeyeol Lee
If you’ve ever tried to cram for an exam, you know that it’s easier to memorize something if you learn the information in shorter, spaced-out sessions. These dynamics are as relevant to each individual cell’s existence as they are to ours. Claire Evans reports: www.quantamagazine.org/what-can-a-c...
What Can a Cell Remember? | Quanta Magazine
A small but enthusiastic group of neuroscientists is exhuming overlooked experiments and performing new ones to explore whether cells record past experiences — fundamentally challenging what memory is...
www.quantamagazine.org
July 30, 2025 at 2:34 PM
If you’ve ever tried to cram for an exam, you know that it’s easier to memorize something if you learn the information in shorter, spaced-out sessions. These dynamics are as relevant to each individual cell’s existence as they are to ours. Claire Evans reports: www.quantamagazine.org/what-can-a-c...
Reposted by Daeyeol Lee
Happy 107th Birthday, Brenda Milner! Her contributions to neuropsychology shaped the way we understand the human brain. From surviving two world wars and two pandemics, to paving the way for future generations of researchers, Milner’s legacy continues. @mcgill.ca @cusm-muhc.bsky.social
July 15, 2025 at 2:05 PM
Happy 107th Birthday, Brenda Milner! Her contributions to neuropsychology shaped the way we understand the human brain. From surviving two world wars and two pandemics, to paving the way for future generations of researchers, Milner’s legacy continues. @mcgill.ca @cusm-muhc.bsky.social
Reposted by Daeyeol Lee
In this “Brain Inspired” episode, Paul Middlebrooks and Xiao-Jing Wang discuss how neuroscience has changed over the past 50 years, and how Wang believes modern theoretical tools will lead to a new era of “cross-levels mechanistic understanding.” Listen now: www.thetransmitter.org/brain-inspir...
Xiao-Jing Wang outlines the future of theoretical neuroscience
Wang discusses why he decided the time was right for a new theoretical neuroscience textbook and how bifurcation is a key missing concept in neuroscience explanations.
www.thetransmitter.org
July 2, 2025 at 2:40 PM
In this “Brain Inspired” episode, Paul Middlebrooks and Xiao-Jing Wang discuss how neuroscience has changed over the past 50 years, and how Wang believes modern theoretical tools will lead to a new era of “cross-levels mechanistic understanding.” Listen now: www.thetransmitter.org/brain-inspir...
Reposted by Daeyeol Lee
Domestication of dogs induced the expansion of the neocortex and reduction in size of subcortical structures:
www.jneurosci.org/content/45/2...
Reminds me of a theory I once heard that humans basically self-domesticated themselves.
www.jneurosci.org/content/45/2...
Reminds me of a theory I once heard that humans basically self-domesticated themselves.
Brain–Behavior Differences in Premodern and Modern Lineages of Domestic Dogs
Although domestic dogs were the first domesticated species, the nature of dog domestication remains a topic of ongoing debate. In particular, brain and behavior changes associated with different stage...
www.jneurosci.org
July 2, 2025 at 6:27 PM
Domestication of dogs induced the expansion of the neocortex and reduction in size of subcortical structures:
www.jneurosci.org/content/45/2...
Reminds me of a theory I once heard that humans basically self-domesticated themselves.
www.jneurosci.org/content/45/2...
Reminds me of a theory I once heard that humans basically self-domesticated themselves.
Reposted by Daeyeol Lee
Thrilled to see our TinyRNN paper in @nature! We show how tiny RNNs predict choices of individual subjects accurately while staying fully interpretable. This approach can transform how we model cognitive processes in both healthy and disordered decisions. doi.org/10.1038/s415...
Discovering cognitive strategies with tiny recurrent neural networks - Nature
Modelling biological decision-making with tiny recurrent neural networks enables more accurate predictions of animal choices than classical cognitive models and offers insights into the underlying cog...
doi.org
July 2, 2025 at 7:03 PM
Thrilled to see our TinyRNN paper in @nature! We show how tiny RNNs predict choices of individual subjects accurately while staying fully interpretable. This approach can transform how we model cognitive processes in both healthy and disordered decisions. doi.org/10.1038/s415...
Reposted by Daeyeol Lee
The neurons that encode sequential information into working memory do not fire in that same order during recall, a finding that is at odds with a long-standing theory. Read more in this month’s Null and Noteworthy.
By @ldattaro.bsky.social
#neuroskyence
www.thetransmitter.org/null-and-not...
By @ldattaro.bsky.social
#neuroskyence
www.thetransmitter.org/null-and-not...
Null and Noteworthy: Neurons tracking sequences don’t fire in order
Instead, neurons encode the position of sequential items in working memory based on when they fire during ongoing brain wave oscillations—a finding that challenges a long-standing theory.
www.thetransmitter.org
June 30, 2025 at 4:08 PM
The neurons that encode sequential information into working memory do not fire in that same order during recall, a finding that is at odds with a long-standing theory. Read more in this month’s Null and Noteworthy.
By @ldattaro.bsky.social
#neuroskyence
www.thetransmitter.org/null-and-not...
By @ldattaro.bsky.social
#neuroskyence
www.thetransmitter.org/null-and-not...
Reposted by Daeyeol Lee
Short new piece on aphantasia just out in TiCS: www.sciencedirect.com/science/arti... Key idea: aphantasia often involves a lack of *visual-object* imagery (explaining subjective reports & objective correlates) but selectively spared *spatial* imagery (explaining preserved task performance).
Spared spatial imagery solves the puzzle of aphantasia
www.sciencedirect.com
June 28, 2025 at 1:10 PM
Short new piece on aphantasia just out in TiCS: www.sciencedirect.com/science/arti... Key idea: aphantasia often involves a lack of *visual-object* imagery (explaining subjective reports & objective correlates) but selectively spared *spatial* imagery (explaining preserved task performance).
Reposted by Daeyeol Lee
Wonderful to see this piece out!
I really think we as a field are converging on a unified account of the hippocampus as a modality agnostic, task-relevant, sequence prediction machine.
I bet that within the next decade we will have a complete computational model of the hippocampus. 🧠📈 🧪
I really think we as a field are converging on a unified account of the hippocampus as a modality agnostic, task-relevant, sequence prediction machine.
I bet that within the next decade we will have a complete computational model of the hippocampus. 🧠📈 🧪
Several new lines of evidence are beginning to reconcile long-standing debates about hippocampal function, prompting neuroscientists to rethink how the region carries out its diverse tasks.
By Natalia Mesa
#neuroskyence
www.thetransmitter.org/memory/expan...
By Natalia Mesa
#neuroskyence
www.thetransmitter.org/memory/expan...
Expanded view of hippocampal function comes into focus
After decades of debate, the region’s role is being rewritten. Rather than using sensory input to simply log key points in time and space, the hippocampus may serve to contextualize our experiences…
www.thetransmitter.org
June 24, 2025 at 3:25 PM
Wonderful to see this piece out!
I really think we as a field are converging on a unified account of the hippocampus as a modality agnostic, task-relevant, sequence prediction machine.
I bet that within the next decade we will have a complete computational model of the hippocampus. 🧠📈 🧪
I really think we as a field are converging on a unified account of the hippocampus as a modality agnostic, task-relevant, sequence prediction machine.
I bet that within the next decade we will have a complete computational model of the hippocampus. 🧠📈 🧪
Reposted by Daeyeol Lee
Out today in @nature.com: we show that individual neurons have diverse tuning to a decision variable computed by the entire population, revealing a unifying geometric principle for the encoding of sensory and dynamic cognitive variables.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
June 25, 2025 at 10:38 PM
Out today in @nature.com: we show that individual neurons have diverse tuning to a decision variable computed by the entire population, revealing a unifying geometric principle for the encoding of sensory and dynamic cognitive variables.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Daeyeol Lee
Delighted to be the opening chapter of this brilliantly conceived (and beautifully covered!) new interdisciplinary collection on Space, Time, and Memory edited by the wonderful Lynn Nadel and Sara Aronowitz. Even better, the whole thing is free to download here: library.oapen.org/bitstream/ha...
June 10, 2025 at 12:10 PM
Delighted to be the opening chapter of this brilliantly conceived (and beautifully covered!) new interdisciplinary collection on Space, Time, and Memory edited by the wonderful Lynn Nadel and Sara Aronowitz. Even better, the whole thing is free to download here: library.oapen.org/bitstream/ha...
Reposted by Daeyeol Lee
May 4, 2025 at 4:41 PM
Reposted by Daeyeol Lee
i have uploaded this preprint a while back, but hadn't promoted it directly here. in this piece i explain why i can no longer recommend trainees to participate in my former home field.
The End of Conscioussness - osf.io/preprints/ps...
but i've learned a lot. thank you for everything.
🧠📈
The End of Conscioussness - osf.io/preprints/ps...
but i've learned a lot. thank you for everything.
🧠📈
OSF
osf.io
April 30, 2025 at 11:18 PM
i have uploaded this preprint a while back, but hadn't promoted it directly here. in this piece i explain why i can no longer recommend trainees to participate in my former home field.
The End of Conscioussness - osf.io/preprints/ps...
but i've learned a lot. thank you for everything.
🧠📈
The End of Conscioussness - osf.io/preprints/ps...
but i've learned a lot. thank you for everything.
🧠📈
Reposted by Daeyeol Lee
Amidst all the arguments, its important to remember science is all about love … #AGIComics
November 21, 2024 at 6:30 AM
Amidst all the arguments, its important to remember science is all about love … #AGIComics
Reposted by Daeyeol Lee
Why acting freely requires constraints (from Sarah Bakewell’s wonderful book about existentialism)
April 5, 2025 at 3:54 PM
Why acting freely requires constraints (from Sarah Bakewell’s wonderful book about existentialism)