Fred Hutch Basic Sciences Division
@basicsci.fredhutch.org
Making Foundational Discoveries @fredhutch.org
fredhutch.org/basicsciences
fredhutch.org/basicsciences
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2025 was an exceptional year for the Basic Sciences Division. We celebrated @fredhutch.org’s 50th anniversary, faculty, trainees, and staff receiving numerous awards, the retirements of Drs. Jon Cooper and Michael Emerman, and so much more.
Get the highlights in our annual report: buff.ly/xQ8hsUM
Get the highlights in our annual report: buff.ly/xQ8hsUM
“Gene regulation in bacteria and eukaryotes with synthetic CRISPR-Cas systems"
We’re excited to have Dr. Jesse Zalatan joining us from @uwchemistry.bsky.social to speak at the first Current Biology Seminar of 2026! For all our @FredHutch.org colleagues, don’t miss a great talk at noon in Pelton!
We’re excited to have Dr. Jesse Zalatan joining us from @uwchemistry.bsky.social to speak at the first Current Biology Seminar of 2026! For all our @FredHutch.org colleagues, don’t miss a great talk at noon in Pelton!
January 13, 2026 at 6:15 PM
“Gene regulation in bacteria and eukaryotes with synthetic CRISPR-Cas systems"
We’re excited to have Dr. Jesse Zalatan joining us from @uwchemistry.bsky.social to speak at the first Current Biology Seminar of 2026! For all our @FredHutch.org colleagues, don’t miss a great talk at noon in Pelton!
We’re excited to have Dr. Jesse Zalatan joining us from @uwchemistry.bsky.social to speak at the first Current Biology Seminar of 2026! For all our @FredHutch.org colleagues, don’t miss a great talk at noon in Pelton!
Can’t wait for the first Friday Afternoon Seminars of 2026!
Excited to hear about the latest research from Kami Ahmad in the Henikoff Lab and Wei Li from Human Biology’s Berjona Lab. For all our @FredHutch.org colleagues, join us in Pelton at 4PM for two great talks!
Excited to hear about the latest research from Kami Ahmad in the Henikoff Lab and Wei Li from Human Biology’s Berjona Lab. For all our @FredHutch.org colleagues, join us in Pelton at 4PM for two great talks!
January 9, 2026 at 9:14 PM
Can’t wait for the first Friday Afternoon Seminars of 2026!
Excited to hear about the latest research from Kami Ahmad in the Henikoff Lab and Wei Li from Human Biology’s Berjona Lab. For all our @FredHutch.org colleagues, join us in Pelton at 4PM for two great talks!
Excited to hear about the latest research from Kami Ahmad in the Henikoff Lab and Wei Li from Human Biology’s Berjona Lab. For all our @FredHutch.org colleagues, join us in Pelton at 4PM for two great talks!
Reposted by Fred Hutch Basic Sciences Division
"I don't see any reason to think that this is an unprecedentedly bad one, but current indicators are that it may be substantially more severe than the typical winter flu season," said @jbloomlab.bsky.social, a scientist at Fred Hutch who studies viral evolution. https://cbsn.ws/4qBApgt
Flu season is ramping up, and some experts are "pretty worried"
Doctors and scientists say this year's influenza season could be tougher than usual, with a new version of the flu virus, called H3N2, spreading quickly.
cbsn.ws
January 5, 2026 at 9:50 PM
"I don't see any reason to think that this is an unprecedentedly bad one, but current indicators are that it may be substantially more severe than the typical winter flu season," said @jbloomlab.bsky.social, a scientist at Fred Hutch who studies viral evolution. https://cbsn.ws/4qBApgt
Reposted by Fred Hutch Basic Sciences Division
Apply for the Dr. Eddie Méndez Scholar Award! Honoring a Fred Hutch physician-scientist’s legacy, this award supports outstanding postdocs advancing cancer, infectious disease & basic science research. Details: https://bit.ly/49w4UxI #cancer #postdoc #science
January 8, 2026 at 8:11 PM
Apply for the Dr. Eddie Méndez Scholar Award! Honoring a Fred Hutch physician-scientist’s legacy, this award supports outstanding postdocs advancing cancer, infectious disease & basic science research. Details: https://bit.ly/49w4UxI #cancer #postdoc #science
We are thrilled to congratulate Dr. Toshio Tsukiyama on being awarded the David and Deborah Lycette Endowed Chair for Cancer Research. This endowment was made possible through a generous gift from David and Deborah Lycette. www.fredhutch.org/en/ways-to-g...
January 5, 2026 at 9:34 PM
We are thrilled to congratulate Dr. Toshio Tsukiyama on being awarded the David and Deborah Lycette Endowed Chair for Cancer Research. This endowment was made possible through a generous gift from David and Deborah Lycette. www.fredhutch.org/en/ways-to-g...
Reposted by Fred Hutch Basic Sciences Division
.@fredhutch.org is seeking applications for the 8th Annual Dr. Eddie Méndez Scholar Award which recognizes outstanding postdoctoral fellows from any discipline who are conducting cancer, infectious disease or basic science research. Learn more and apply: https://apply.interfolio.com/176955
December 28, 2025 at 5:10 PM
.@fredhutch.org is seeking applications for the 8th Annual Dr. Eddie Méndez Scholar Award which recognizes outstanding postdoctoral fellows from any discipline who are conducting cancer, infectious disease or basic science research. Learn more and apply: https://apply.interfolio.com/176955
Reposted by Fred Hutch Basic Sciences Division
Here's to another year of bringing together groundbreaking science and comprehensive care to push the boundaries of what’s possible for patients and their loved ones. Wishing you a #HappyNewYear from all of us at Fred Hutch! 🎉
January 1, 2026 at 8:00 AM
Here's to another year of bringing together groundbreaking science and comprehensive care to push the boundaries of what’s possible for patients and their loved ones. Wishing you a #HappyNewYear from all of us at Fred Hutch! 🎉
Reposted by Fred Hutch Basic Sciences Division
@pravrutharaman.bsky.social got super intrigued about EZHIP/CATACOMB, previously identified as a histone H3K27M mimic of PRC2. You can read about her efforts here: www.biorxiv.org/content/10.6... We hope these analyses will help spur more analyses in this very cool gene! 1/
Dynamic evolution of EZHIP, an inhibitor of the Polycomb Repressive Complex 2 in mammals
The Polycomb Repressive Complex 2 (PRC2) is an ancient, conserved chromatin-interacting complex that controls gene expression, facilitating differentiation and cellular identity during development. It...
www.biorxiv.org
December 13, 2025 at 10:08 PM
@pravrutharaman.bsky.social got super intrigued about EZHIP/CATACOMB, previously identified as a histone H3K27M mimic of PRC2. You can read about her efforts here: www.biorxiv.org/content/10.6... We hope these analyses will help spur more analyses in this very cool gene! 1/
2025 was an exceptional year for the Basic Sciences Division. We celebrated @fredhutch.org’s 50th anniversary, faculty, trainees, and staff receiving numerous awards, the retirements of Drs. Jon Cooper and Michael Emerman, and so much more.
Get the highlights in our annual report: buff.ly/xQ8hsUM
Get the highlights in our annual report: buff.ly/xQ8hsUM
December 12, 2025 at 7:36 PM
2025 was an exceptional year for the Basic Sciences Division. We celebrated @fredhutch.org’s 50th anniversary, faculty, trainees, and staff receiving numerous awards, the retirements of Drs. Jon Cooper and Michael Emerman, and so much more.
Get the highlights in our annual report: buff.ly/xQ8hsUM
Get the highlights in our annual report: buff.ly/xQ8hsUM
Reposted by Fred Hutch Basic Sciences Division
Last seminar of 2025: Dr. @sanjaysrivatsan.bsky.social from @fredhutch.org discussed capsule-based genome sequencing and lineage tracing. Thank you to everyone who joined us in person and via Zoom. Recording available on our YouTube channel: youtu.be/ykS0q7Pl3xo?...
@jlmcfalinefigueroa.bsky.social
@jlmcfalinefigueroa.bsky.social
December 11, 2025 at 2:04 PM
Last seminar of 2025: Dr. @sanjaysrivatsan.bsky.social from @fredhutch.org discussed capsule-based genome sequencing and lineage tracing. Thank you to everyone who joined us in person and via Zoom. Recording available on our YouTube channel: youtu.be/ykS0q7Pl3xo?...
@jlmcfalinefigueroa.bsky.social
@jlmcfalinefigueroa.bsky.social
Today we celebrated the retirement of research administration manager Katrina Akioka after 13 years @fredhutch.org. She leaves behind a legacy of service to Fred Hutch, the division, and the many faculty and labs she supported over the years. We wish her all the best in retirement.
December 9, 2025 at 1:12 AM
Today we celebrated the retirement of research administration manager Katrina Akioka after 13 years @fredhutch.org. She leaves behind a legacy of service to Fred Hutch, the division, and the many faculty and labs she supported over the years. We wish her all the best in retirement.
Reposted by Fred Hutch Basic Sciences Division
Happening TODAY - Timothy Yu’s ( @timyu.bsky.social ) dissertation defense!
Title: Epistasis and pleiotropy in viral protein evolution
Lab: Bloom Lab, FH
When: Monday, December 8, 2 p.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building) & Zoom (email [email protected] for link)
Title: Epistasis and pleiotropy in viral protein evolution
Lab: Bloom Lab, FH
When: Monday, December 8, 2 p.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building) & Zoom (email [email protected] for link)
December 8, 2025 at 4:00 PM
Happening TODAY - Timothy Yu’s ( @timyu.bsky.social ) dissertation defense!
Title: Epistasis and pleiotropy in viral protein evolution
Lab: Bloom Lab, FH
When: Monday, December 8, 2 p.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building) & Zoom (email [email protected] for link)
Title: Epistasis and pleiotropy in viral protein evolution
Lab: Bloom Lab, FH
When: Monday, December 8, 2 p.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building) & Zoom (email [email protected] for link)
It’s almost the best part of the week: Friday Afternoon Seminars!
Can’t wait to learn about the latest research from Changkun Hu in the @suebiggins.bsky.social Lab and Haolong Li from the Human Biology Division. For all our @FredHutch.org colleagues, join us in Pelton at 4PM for two great talks!
Can’t wait to learn about the latest research from Changkun Hu in the @suebiggins.bsky.social Lab and Haolong Li from the Human Biology Division. For all our @FredHutch.org colleagues, join us in Pelton at 4PM for two great talks!
December 5, 2025 at 10:29 PM
It’s almost the best part of the week: Friday Afternoon Seminars!
Can’t wait to learn about the latest research from Changkun Hu in the @suebiggins.bsky.social Lab and Haolong Li from the Human Biology Division. For all our @FredHutch.org colleagues, join us in Pelton at 4PM for two great talks!
Can’t wait to learn about the latest research from Changkun Hu in the @suebiggins.bsky.social Lab and Haolong Li from the Human Biology Division. For all our @FredHutch.org colleagues, join us in Pelton at 4PM for two great talks!
Reposted by Fred Hutch Basic Sciences Division
Very proud of our lab manager, Aida de la Cruz, for winning the Nancy Hutchinson mentoring award (www.fredhutch.org/en/education...) based on her mentees' nominations.
@fredhutch.org @basicsci.fredhutch.org
Internal news: centernet.fredhutch.org/n/2025/12/sp...
@fredhutch.org @basicsci.fredhutch.org
Internal news: centernet.fredhutch.org/n/2025/12/sp...
December 5, 2025 at 7:43 PM
Very proud of our lab manager, Aida de la Cruz, for winning the Nancy Hutchinson mentoring award (www.fredhutch.org/en/education...) based on her mentees' nominations.
@fredhutch.org @basicsci.fredhutch.org
Internal news: centernet.fredhutch.org/n/2025/12/sp...
@fredhutch.org @basicsci.fredhutch.org
Internal news: centernet.fredhutch.org/n/2025/12/sp...
Congratulations to Aida de la Cruz, lab manager in the @harmitmalik.bsky.social Lab, on receiving the Hutchison Award! The award, presented by @fredhutch.org SPAC and named for Dr. Nancy Hutchison, recognizes phenomenal mentorship. It also comes with an awesome personalized bobblehead.
December 5, 2025 at 9:30 PM
Congratulations to Aida de la Cruz, lab manager in the @harmitmalik.bsky.social Lab, on receiving the Hutchison Award! The award, presented by @fredhutch.org SPAC and named for Dr. Nancy Hutchison, recognizes phenomenal mentorship. It also comes with an awesome personalized bobblehead.
Reposted by Fred Hutch Basic Sciences Division
See you next week for Timothy Yu’s (@timyu.bsky.social ) dissertation defense!
Title: Epistasis and pleiotropy in viral protein evolution
Lab: Bloom Lab, FH
When: Monday, December 8, 2 p.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building) & Zoom (email [email protected] for link)
Title: Epistasis and pleiotropy in viral protein evolution
Lab: Bloom Lab, FH
When: Monday, December 8, 2 p.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building) & Zoom (email [email protected] for link)
December 1, 2025 at 10:00 PM
See you next week for Timothy Yu’s (@timyu.bsky.social ) dissertation defense!
Title: Epistasis and pleiotropy in viral protein evolution
Lab: Bloom Lab, FH
When: Monday, December 8, 2 p.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building) & Zoom (email [email protected] for link)
Title: Epistasis and pleiotropy in viral protein evolution
Lab: Bloom Lab, FH
When: Monday, December 8, 2 p.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building) & Zoom (email [email protected] for link)
We have two great speakers lined up for Friday Afternoon Seminars!
For everyone @FredHutch.org, join us at 4:00 in Pelton to hear Gardenia Sanchez from the @yarimura.bsky.social and Saurabh Verma from Human Biology’s Nelson Lab share their latest discoveries!
For everyone @FredHutch.org, join us at 4:00 in Pelton to hear Gardenia Sanchez from the @yarimura.bsky.social and Saurabh Verma from Human Biology’s Nelson Lab share their latest discoveries!
November 21, 2025 at 9:53 PM
We have two great speakers lined up for Friday Afternoon Seminars!
For everyone @FredHutch.org, join us at 4:00 in Pelton to hear Gardenia Sanchez from the @yarimura.bsky.social and Saurabh Verma from Human Biology’s Nelson Lab share their latest discoveries!
For everyone @FredHutch.org, join us at 4:00 in Pelton to hear Gardenia Sanchez from the @yarimura.bsky.social and Saurabh Verma from Human Biology’s Nelson Lab share their latest discoveries!
We’re excited to have Edgar Fernandes from the Talbot Lab and Supriya Amonkar from Human Biology’s Galloway Lab sharing their latest research at Friday Afternoon Seminars. For all our @FredHutch.org colleagues, don’t miss two fantastic talks today at 4:00!
November 14, 2025 at 10:10 PM
We’re excited to have Edgar Fernandes from the Talbot Lab and Supriya Amonkar from Human Biology’s Galloway Lab sharing their latest research at Friday Afternoon Seminars. For all our @FredHutch.org colleagues, don’t miss two fantastic talks today at 4:00!
Excited for two great speakers at Friday Afternoon Seminars!
For all our @FredHutch.org colleagues , join us at 4:00 in Pelton to hear Alina Lorant from the Koch Lab and Naomi Yamamoto from Human Biology’s Kugel Lab share their latest research!
For all our @FredHutch.org colleagues , join us at 4:00 in Pelton to hear Alina Lorant from the Koch Lab and Naomi Yamamoto from Human Biology’s Kugel Lab share their latest research!
November 7, 2025 at 9:48 PM
Excited for two great speakers at Friday Afternoon Seminars!
For all our @FredHutch.org colleagues , join us at 4:00 in Pelton to hear Alina Lorant from the Koch Lab and Naomi Yamamoto from Human Biology’s Kugel Lab share their latest research!
For all our @FredHutch.org colleagues , join us at 4:00 in Pelton to hear Alina Lorant from the Koch Lab and Naomi Yamamoto from Human Biology’s Kugel Lab share their latest research!
Reposted by Fred Hutch Basic Sciences Division
Join us for Darren Mallett’s dissertation defense!
Title: Uncovering the mechanisms that control unattached kinetochore clustering
Lab: Biggins Lab, FH
When: Friday, November 14, 10 a.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building)
Title: Uncovering the mechanisms that control unattached kinetochore clustering
Lab: Biggins Lab, FH
When: Friday, November 14, 10 a.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building)
October 31, 2025 at 5:00 PM
Join us for Darren Mallett’s dissertation defense!
Title: Uncovering the mechanisms that control unattached kinetochore clustering
Lab: Biggins Lab, FH
When: Friday, November 14, 10 a.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building)
Title: Uncovering the mechanisms that control unattached kinetochore clustering
Lab: Biggins Lab, FH
When: Friday, November 14, 10 a.m. PST
Where: Fred Hutch Pelton Auditorium (Weintraub Building)
Reposted by Fred Hutch Basic Sciences Division
Congrats to Steven Henikoff, PhD, of @basicsci.fredhutch.org on receiving the 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research! @brandeisuniversity.bsky.social recognized Henikoff with this prestigious award for his innovative studies on gene expression.
Brandeis University honors Fred Hutch molecular biologist
Dr. Steven Henikoff, a molecular biologist at Fred Hutch Cancer Center, has won the prestigious Rosenstiel Award for Distinguished Work in Basic Medical Research from Brandeis University recognizing h...
www.fredhutch.org
October 31, 2025 at 12:37 PM
Congrats to Steven Henikoff, PhD, of @basicsci.fredhutch.org on receiving the 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research! @brandeisuniversity.bsky.social recognized Henikoff with this prestigious award for his innovative studies on gene expression.
Today we celebrated Dr. Steve Henikoff receiving the Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research. Dr. Henikoff will formally receive the award and present a lecture on his work next April @brandeisuniversity.bsky.social.
www.brandeis.edu/stories/2025...
www.brandeis.edu/stories/2025...
October 29, 2025 at 8:21 PM
Today we celebrated Dr. Steve Henikoff receiving the Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research. Dr. Henikoff will formally receive the award and present a lecture on his work next April @brandeisuniversity.bsky.social.
www.brandeis.edu/stories/2025...
www.brandeis.edu/stories/2025...
Congratulations to Dr. Steve Henikoff on receiving the 55th Rosenstiel Award for his research on genome organization and gene expression! The award is given for recent discoveries of particular originality and importance to basic medical research.
Professor Steven Henikoff receives 55th Rosenstiel Award for research on genome organization and gene expression
October 29, 2025
www.brandeis.edu
October 29, 2025 at 7:06 PM
Congratulations to Dr. Steve Henikoff on receiving the 55th Rosenstiel Award for his research on genome organization and gene expression! The award is given for recent discoveries of particular originality and importance to basic medical research.
Reposted by Fred Hutch Basic Sciences Division
@jhigginswriter.bsky.social wrote an article about my lab and our frog 🐸 at the Hutch! Thank you!
Dr. @yarimura.bsky.social brings frogs back to Fred Hutch after a long absence to study the structure of DNA-linked molecular complexes that change during the cell cycle and malfunction in cancer and other diseases. bit.ly/3J8S5Ae
Frogs help Fred Hutch find the shape of small things
Frogs have made significant contributions to Fred Hutch science over the years as a model organism that shares much of our biology, but they've been absent from the menagerie for about two decades. Dr...
bit.ly
October 29, 2025 at 6:29 AM
@jhigginswriter.bsky.social wrote an article about my lab and our frog 🐸 at the Hutch! Thank you!
"Foundation models for 3D genome architecture and tandem mass spectra"
We’re excited to have @wnoble.bsky.social joining us from @uwgenome.bsky.social to share his latest research at today’s Current Biology Seminar! For all our @fredhutch.org colleagues, don’t miss a great talk at noon in Pelton!
We’re excited to have @wnoble.bsky.social joining us from @uwgenome.bsky.social to share his latest research at today’s Current Biology Seminar! For all our @fredhutch.org colleagues, don’t miss a great talk at noon in Pelton!
October 28, 2025 at 5:19 PM
"Foundation models for 3D genome architecture and tandem mass spectra"
We’re excited to have @wnoble.bsky.social joining us from @uwgenome.bsky.social to share his latest research at today’s Current Biology Seminar! For all our @fredhutch.org colleagues, don’t miss a great talk at noon in Pelton!
We’re excited to have @wnoble.bsky.social joining us from @uwgenome.bsky.social to share his latest research at today’s Current Biology Seminar! For all our @fredhutch.org colleagues, don’t miss a great talk at noon in Pelton!