Bharath Kumar
@bharathkumartv.bsky.social
Intensivist|Trialist|Ph.D. candidate @amsterdamumc.bsky.social
Live and work in Chennai; Bangalorean at heart.
Live and work in Chennai; Bangalorean at heart.
Reposted by Bharath Kumar
Incredible global effort- glad sites from India could collaborate- can't wait to see the results!
Congratulations @dogicuma.bsky.social and the entire global MegaROX team 🙏
Congratulations @dogicuma.bsky.social and the entire global MegaROX team 🙏
The #MegaROXtrial appears to have reached 40,000 patients (plus a few bonus patients enrolled before the website realised the enrolment target was met)
November 12, 2025 at 9:20 AM
Incredible global effort- glad sites from India could collaborate- can't wait to see the results!
Congratulations @dogicuma.bsky.social and the entire global MegaROX team 🙏
Congratulations @dogicuma.bsky.social and the entire global MegaROX team 🙏
Reposted by Bharath Kumar
#MegaROXtrial 27 to go. 39973 enrolled.
November 11, 2025 at 6:25 PM
#MegaROXtrial 27 to go. 39973 enrolled.
Reposted by Bharath Kumar
ICU-acquired weakness is common; protocolised active rehabilitation helps, while higher enteral protein alone shows no outcome benefit. Priorities include early prognostic markers, better diagnostics and personalised care. zurl.co/BBlDf
November 6, 2025 at 5:00 PM
ICU-acquired weakness is common; protocolised active rehabilitation helps, while higher enteral protein alone shows no outcome benefit. Priorities include early prognostic markers, better diagnostics and personalised care. zurl.co/BBlDf
Reposted by Bharath Kumar
The #MegaROXtrial has fewer than 150 patients left to enrol
November 6, 2025 at 5:59 PM
The #MegaROXtrial has fewer than 150 patients left to enrol
Reposted by Bharath Kumar
The intensive care medicine research agenda for the management of ICU acquired weakness: a multinational, interprofessional perspective
CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
November 6, 2025 at 11:12 PM
The intensive care medicine research agenda for the management of ICU acquired weakness: a multinational, interprofessional perspective
CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
Reposted by Bharath Kumar
The #MegaROXtrial has 39800 patients which leaves only 200 left to enrol
November 5, 2025 at 5:23 AM
The #MegaROXtrial has 39800 patients which leaves only 200 left to enrol
Our paper on a core outcome measurement set for clinical trials in dengue is now published in The Lancet Infectious Diseases : www.thelancet.com/journals/lan...
Core outcome measurement set for clinical trials in dengue: an international Delphi consensus study (DEN-CORE)
Dengue, caused by any one of four distinct virus serotypes, is the most rapidly spreading
mosquito-borne viral disease worldwide. It is a primary arboviral infection with increasing
global incidence, ...
www.thelancet.com
October 8, 2025 at 7:11 AM
Our paper on a core outcome measurement set for clinical trials in dengue is now published in The Lancet Infectious Diseases : www.thelancet.com/journals/lan...
Reposted by Bharath Kumar
Dengue outbreak in Sudan 👇. We need better tools and investment to tackle dengue
Dengue outbreak in Sudan, where health infrastructures are devastated by the conflict. More than 2.000 cases of #dengue reported, with the real number probably much higher. We need better tools for dengue, including treatments. www.reuters.com/business/hea...
Dengue fever ravages Sudan as infrastructure battered by war
Tens of thousands of Sudanese people have fallen victim to dengue fever and other diseases, Sudan's health minister said, as seasonal rains further test infrastructure and hospitals devastated by conflict.
www.reuters.com
September 25, 2025 at 11:56 AM
Dengue outbreak in Sudan 👇. We need better tools and investment to tackle dengue
Reposted by Bharath Kumar
This👇 …. often unseen but crucial role
Statisticians are central to patient safety in clinical trials.
From designing stopping rules to monitoring adverse events, we ensure risks are detected early - protecting participants while maintaining trial integrity.
🔗 ukcrc-ctu.org.uk
#Statistics #UKCTUNetwork #WorldPatientSafetyDay2025
From designing stopping rules to monitoring adverse events, we ensure risks are detected early - protecting participants while maintaining trial integrity.
🔗 ukcrc-ctu.org.uk
#Statistics #UKCTUNetwork #WorldPatientSafetyDay2025
September 17, 2025 at 11:33 AM
This👇 …. often unseen but crucial role
Reposted by Bharath Kumar
Reposted by Bharath Kumar
I seem to have been discussing pilot and feasibility studies a lot this week. One question often asked is how big should my pilot/feasibility study be? 1/6
#MethodologyMonday #124
#MethodologyMonday #124
September 8, 2025 at 6:42 AM
I seem to have been discussing pilot and feasibility studies a lot this week. One question often asked is how big should my pilot/feasibility study be? 1/6
#MethodologyMonday #124
#MethodologyMonday #124
Reposted by Bharath Kumar
The #MegaROXtrial has reached 37851 enrolments. 38k likely next week and 40k on the cards for Nov.
August 28, 2025 at 7:36 PM
The #MegaROXtrial has reached 37851 enrolments. 38k likely next week and 40k on the cards for Nov.
Reposted by Bharath Kumar
There has been a lot of debate recently about the promise of real world data - the routine (observational) data collected on patients eg treatments received, clinical outcomes etc – for estimating treatment effects. But can they deliver? 1/9
#MethodologyMonday #123
#MethodologyMonday #123
August 18, 2025 at 6:35 AM
There has been a lot of debate recently about the promise of real world data - the routine (observational) data collected on patients eg treatments received, clinical outcomes etc – for estimating treatment effects. But can they deliver? 1/9
#MethodologyMonday #123
#MethodologyMonday #123
Reposted by Bharath Kumar
I am delighted to be joining the Editorial Board of @bmj.com as a freelance Clinical Editorial Advisor. I look forward to bringing acute/critical care and LMIC perspectives to the editorial decision-making table.
August 14, 2025 at 2:52 PM
I am delighted to be joining the Editorial Board of @bmj.com as a freelance Clinical Editorial Advisor. I look forward to bringing acute/critical care and LMIC perspectives to the editorial decision-making table.
Reposted by Bharath Kumar
Critical care research remains marked by epistemic inequity, with LMIC contributions often undercited, excluded from authorship, and marginalised in global forums, reinforcing structural power imbalances and limiting diverse knowledge production. zurl.co/lLasi
August 14, 2025 at 9:03 AM
Reposted by Bharath Kumar
🚨 The #ESICM 𝟯𝗚 𝗚𝗿𝗮𝗻𝘁 – 2nd Call is 𝗢𝗣𝗘𝗡 𝘂𝗻𝘁𝗶𝗹 𝟮𝟳 𝗔𝘂𝗴! 💶 €300K for research on 𝗿𝗮𝗽𝗶𝗱 𝗶𝗻𝗳𝗲𝗰𝘁𝗶𝗼𝗻 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝘁𝗶𝗰𝘀 𝗶𝗻 𝘁𝗵𝗲 #ICU, in collaboration with bioMérieux!
We invite bold, hypothesis-driven proposals with real-world impact on #AMR & patient outcomes.
🔗 www.esicm.org/3g-giant-gre...
#ICUresearch
We invite bold, hypothesis-driven proposals with real-world impact on #AMR & patient outcomes.
🔗 www.esicm.org/3g-giant-gre...
#ICUresearch
Giant Great Grant - "3G" - ESICM
The 2nd edition of the 3G project is now open - thanks to the support of Biomérieux. We call on all healthcare professionals to submit a proposal focusing on FAST ID/AST to implement antimicrobial stewardship in critically ill patients.
www.esicm.org
August 1, 2025 at 12:00 PM
🚨 The #ESICM 𝟯𝗚 𝗚𝗿𝗮𝗻𝘁 – 2nd Call is 𝗢𝗣𝗘𝗡 𝘂𝗻𝘁𝗶𝗹 𝟮𝟳 𝗔𝘂𝗴! 💶 €300K for research on 𝗿𝗮𝗽𝗶𝗱 𝗶𝗻𝗳𝗲𝗰𝘁𝗶𝗼𝗻 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝘁𝗶𝗰𝘀 𝗶𝗻 𝘁𝗵𝗲 #ICU, in collaboration with bioMérieux!
We invite bold, hypothesis-driven proposals with real-world impact on #AMR & patient outcomes.
🔗 www.esicm.org/3g-giant-gre...
#ICUresearch
We invite bold, hypothesis-driven proposals with real-world impact on #AMR & patient outcomes.
🔗 www.esicm.org/3g-giant-gre...
#ICUresearch
Reposted by Bharath Kumar
The 37000th patient was enrolled in the #MegaROXtrial in Casey Hospital, Australia at 05:01am local time. 3K to go.
July 30, 2025 at 10:17 PM
The 37000th patient was enrolled in the #MegaROXtrial in Casey Hospital, Australia at 05:01am local time. 3K to go.
Reposted by Bharath Kumar
The #MegaROXtrial has 36907 patients enrolled. 37K is days away. We will get to 40K in the last quarter of 2025.
July 26, 2025 at 8:18 PM
The #MegaROXtrial has 36907 patients enrolled. 37K is days away. We will get to 40K in the last quarter of 2025.
Reposted by Bharath Kumar
We often now hear the term “Bayesian borrowing” in trials. But what is Bayesian borrowing and what are the pros and cons around its use? 1/6
#MethodologyMonday #122
#MethodologyMonday #122
July 21, 2025 at 7:10 AM
We often now hear the term “Bayesian borrowing” in trials. But what is Bayesian borrowing and what are the pros and cons around its use? 1/6
#MethodologyMonday #122
#MethodologyMonday #122
Reposted by Bharath Kumar
Heat waves make the news when they impact Global North countries
Constant, extreme heat is a daily fact of life for billions in the Global South
Constant, extreme heat is a daily fact of life for billions in the Global South
July 17, 2025 at 9:53 AM
Heat waves make the news when they impact Global North countries
Constant, extreme heat is a daily fact of life for billions in the Global South
Constant, extreme heat is a daily fact of life for billions in the Global South
Reposted by Bharath Kumar
36500 patients enrolled in the #MegaROXtrial. Only 3500 to go.
July 12, 2025 at 7:25 AM
36500 patients enrolled in the #MegaROXtrial. Only 3500 to go.
Our pilot trial evaluating dexamethasone in patients hospitalised with dengue is now active at 5 hospitals and we enrolled our 5th trial participant today.
We are funded by @uoftcities.bsky.social and the University of Toronto India foundation. Trial sponsored by @georgeinstitute.bsky.social
We are funded by @uoftcities.bsky.social and the University of Toronto India foundation. Trial sponsored by @georgeinstitute.bsky.social
July 10, 2025 at 9:12 AM
Our pilot trial evaluating dexamethasone in patients hospitalised with dengue is now active at 5 hospitals and we enrolled our 5th trial participant today.
We are funded by @uoftcities.bsky.social and the University of Toronto India foundation. Trial sponsored by @georgeinstitute.bsky.social
We are funded by @uoftcities.bsky.social and the University of Toronto India foundation. Trial sponsored by @georgeinstitute.bsky.social