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(ง •̀_•́)ง LYRE ☆

@briaryre.bsky.social

210 followers 450 following 1.9K posts

☆him/her☆ ☆Independent artist of too many disciplines ☆I love videogames and catboys ❗no minors/occasional 🔞❗ 🎨↻ heavy🎨 Tags: #Lyrearts | #Yurirkha | #cosprog

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(ง •̀_•́)ง LYRE ☆ @briaryre.bsky.social · Apr 21

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kell ☆ @corviida.bsky.social · Aug 10

i love maelle and gustave so much dont even TALK to me!!! #expedition33

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kell ☆ @corviida.bsky.social · Aug 18

lineup of the beloved #expedition33 !!

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kell ☆ @corviida.bsky.social · Sep 3

verso doodles... voodles, if you will #expedition33

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kell ☆ @corviida.bsky.social · Aug 7

oh verso... ive never seen a man more sad in my life #expedition33

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🦎galileo🍉 @galileogb.bsky.social · 23h

Sonic saying, "Support your local, human, erotica creators. You need chatgpt to suck your e-dick for you? You absolutely fucking LOSER"

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ionomycin @ionomycin.bsky.social · 23h

there's something wrong with the rabbits

a character sitting in a room with a moose skull on the wall. black rabbits surround them in the shadow

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(ง •̀_•́)ง LYRE ☆ @briaryre.bsky.social · 18h

Getting high and going into the new deep dungeon alone to once again complete the quest and then have absolutely no memory of it

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Kim Myatt⁷ @ysvyri.bsky.social · 1d

*deep inhale of dusty breath* What year is it??

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Suzanne ✨🌑 @tendermiasma.com · 1d

Happy #pornfolioday! I'm Suzanne and I draw some boys who are very precious to me 💕
I'm following my dream of drawing them full-time on Patreon so consider enabling me!

🌙 www.patreon.com/tendermiasma

✥ #bg3 #halsin #castlevania #vampirehunterD

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Joshua Fortier @joshuabeeking.bsky.social · 1d

New art on my Patreon, a little NSFW piece so as to make the wait for bigger ones more bearable. Enjoy!
patreon.com/posts/kcd2-h...
#hansry #kcd2

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(ง •̀_•́)ง LYRE ☆ @briaryre.bsky.social · 1d

I have some crazy high financial goals for the end of this year but looking at my estimated income for the coming months I think... this may be pawsible... huge if true

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Xiao Tong 🦋 CTC @velinxi.bsky.social · Jul 31

A dance that never ends #loz

Legend of Zelda fan art. BOTW link and Zelda and dancing in front of a mirror whose reflection shows multiple iterations of other Zelda’s and links dancing together in the background.

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Pach In Eorzea || Brute Bomber's Fan Club @pachineorzea.bsky.social · 2d

Is the guy in the cuck chair supposed to stay quiet or is he allowed to clap and cheer
foxgirlmindcrank

he's supposed to take notes and make an intrigued hum when an interesting plot point occurs

He's supposed to do sideline shonen anime character commentary.

'huh?! impossible! that technique should be impossible to perform... unless!

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سيف | 🇵🇸 @chanafehs.bsky.social · 1d

Happy indigenous peoples day everyone🇵🇸🫶

سيف | 🇵🇸 @chanafehs.bsky.social · Jun 30

palestinian lesbians once again ✨
{ #art #pride }

Digital art Illustration of two women in a tender embrace in front of a arched window. Both women are Palestinian and wearing elaborately decorated traditional thobes. The woman to the left has a deeper skin tone and a tender smile. Her braided black hair is decorated with silver ornaments towards the bottom.

The woman to the right is wearing a heavy coin headdress that has chains leading down to her waist. Her face has subtle tattoos that match those on her hand.

In the arched window behind them there are palm trees in the distance and foliage that coveres the bottom of the window.

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Xiao Tong 🦋 CTC @velinxi.bsky.social · 1d

Expedition 33 doodles. Of course I must always ship the most improbable delusional ships in every fandom I’m in

#verstave

Doodles of Gustave and verso sparring. It looks pretty gay.

Verso at subways. Yes, like the Subways you buy sandwiches at. He looks distraught while there’s a text that says “they fucked his expedition up 52 times”

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Citro @citromiel.bsky.social · 1d

Smooch
#trigun #millymeryl

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Abigail Larson @abigaillarson.com · 27d

a sketch with digital color of a woman resting her head on her arms on top of a open book. Tangled branches envelope her, and a goblin pokes its head over the table.

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Vick @verticalstorm.bsky.social · 2d

*cartoon kiss sfx* mwah

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🕸Nye🐇 comms open! @nigelgraz.bsky.social · 2d

(OC) Midnight creature

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Chise @sailorrooscout.bsky.social · 3d

Researchers envision their vaccine being used as both a treatment and a preventive, and as an approach to treating multiple cancer types.
• www.umass.edu/news/article...

The study has been published in Cell Reports Medicine. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...

🧪🧵⬇️

HIGHLIGHTS
•Lipid NPs carrying STING and TLR4 agonists promote synergistic type I interferons
• NPs drain efficiently to lymph nodes and increase polyfunctional T and B cells
• NPs improve tumor-free outcomes with memory against multiple aggressive tumor models
SUMMARY
We report on the utility of a "super-adjuvant" nanoparticle (NP) system as a modular, customizable platform for next-generation cancer vaccination. Using nanomaterials engineering technology, we aim to harness not only the effective adjuvanticity of whole-pathogen vaccines, but also the safety of subunit vaccines.
Our lipid-based NP platform co-encapsulates agonists of the stimulator of interferon genes (STING) and Toll-like receptor 4 (TLR4) pathways to promote synergistic production of type I interferons and other
proinflammatory cytokines in innate antigen-presenting dendritic cells and macrophages.
Compared to empty NPs and free agonists, dual-adjuvant NPs administered with antigenic peptides or tumor cell lysate promote increased antigen processing and presentation, drain efficiently to nearby lymph nodes, increase polyfunctional tumor-specific T and B cells, and improve tumor-free outcomes upon vaccination and subsequent challenge with multiple aggressive tumor cells.

Graphical Abstract

The vaccine combines two immune-stimulating molecules (adjuvants) in a tiny lipid nanoparticle that enhances both innate and adaptive immune responses. The innate immune system acts as the body’s first line of defense, responding quickly and non-specifically to invaders using cells that release inflammatory signals. The adaptive immune system takes longer to activate but provides a targeted, long-lasting response, training T-cells and B- cells to recognize and remember specific threats. Together, they form a coordinated defense: the innate system alerts and activates the adaptive system, which then delivers precise and durable immunity.

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Chise @sailorrooscout.bsky.social · 3d

GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.

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Brilcrist @brilcrist.bsky.social · 11d

Whumptober 02: Blinded

#Zizkat #KCD2 #Whumptober2025

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(ง •̀_•́)ง LYRE ☆ @briaryre.bsky.social · 2d

You've painted them so beautifully here, I can hardly describe how emotional looking at this and their faces make me!! Henry looks so peaceful...

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Brilcrist @brilcrist.bsky.social · 10d

Whumptober 03: Drowning

What would happened if Henry was drowning in the prologue instead being hit by an arrow?

#KCD2 #Hansry #Whumptober2025

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Brilcrist @brilcrist.bsky.social · 8d

Whumptober 05: Torture⛓️
Wish that interrogation scene was more private n spicy🤧💦

PS: Henry is kneeling in here, not Istvan standing on a barrel~

#Istry #KCD2 #Whumptober2025

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