Danilo Buonsenso
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buonsenso.bsky.social
Danilo Buonsenso
@buonsenso.bsky.social
3.7K followers 100 following 530 posts
Pediatric Infectious Disease doctor.
Fighting to care for children with Long Covid & ME/CFS.
My book on my LONG COVID JOURNEY: https://tinyurl.com/4tsvhwat
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buonsenso.bsky.social
Danilo Buonsenso @buonsenso.bsky.social · Nov 10
as I’m new here,
wanted to tell that I wrote a personal and sentimental book on #longcovid
LONG COVID - MY NO-FILTER TRAVEL JOURNAL

tinyurl.com/4tsvhwat

I retrace main steps under my perspective and no filters, highlighting both the professional and human satisfactions, but also the difficulties
buonsenso.bsky.social
A Pathogenic Monocyte Signature in Long COVID: What It Means for Buonsenso and the Kids

danilobuonsenso.substack.com/p/a-pathogen...
A Pathogenic Monocyte Signature in Long COVID: What It Means for Buonsenso and the Kids
Long COVID has puzzled scientists, clinicians, and families alike for years — especially when children and adolescents continue to struggle with fatigue, shortness of breath, and other persistent symp...
danilobuonsenso.substack.com
February 1, 2026 at 3:54 PM
Reposted by Danilo Buonsenso
longcovidkids.bsky.social
"These findings reinforce an urgent message that children and adolescents can develop #LongCovid not only after an initial infection, but also after reinfection. The public health implications are substantial." @buonsenso.bsky.social

www.thelancet.com/journals/lan...

#LongCovidKids #Children
Long COVID is here to stay—even in children
Post-acute sequelae of SARS-CoV-2 infection (PASC, also known as long COVID) are complex, multisystem, long-lasting complications of SARS-CoV-2 infection that profoundly impact the daily life of those...
www.thelancet.com
January 29, 2026 at 8:59 PM
Reposted by Danilo Buonsenso
valebodi.bsky.social
Long COVID is here to stay—even in children 😢
@buonsenso.bsky.social

These findings reinforce an urgent message that children and adolescents can develop long COVID not only after an initial infection, but also after reinfection. The public health implications are substantial.
Before this study,
Long COVID is here to stay—even in children
Post-acute sequelae of SARS-CoV-2 infection (PASC, also known as long COVID) are complex, multisystem, long-lasting complications of SARS-CoV-2 infection that profoundly impact the daily life of those...
www.thelancet.com
January 29, 2026 at 10:50 PM
buonsenso.bsky.social
Plasmapheresis, apheresis, and why people with Long Covid or ME/CFS talk about them

danilobuonsenso.substack.com/p/plasmapher...
Plasmapheresis, apheresis, and why people with Long Covid or ME/CFS talk about them
as we are implementing a protocol for plasmapheresis in patients with Long Covid and ME/CFS, I wanted to summarize with you what it is and why we are thinking about that.
danilobuonsenso.substack.com
January 25, 2026 at 2:29 PM
buonsenso.bsky.social
Long COVID: When the Fire Inside Never Turns Off — A Personal Reflection

danilobuonsenso.substack.com/p/long-covid...
Long COVID: When the Fire Inside Never Turns Off — A Personal Reflection
Every parent wants their child to be healthy and whole.
danilobuonsenso.substack.com
January 18, 2026 at 7:04 PM
buonsenso.bsky.social
after years of illness and gaslighting, this kid with #LongCovid is leaving again❤️
grateful for this mum’s email.

Why IVIG and immunemodulation work most time is written since two years in my book tinyurl.com/4tsvhwat

and blog substack.com/@mecfslongco...
January 10, 2026 at 12:43 PM
buonsenso.bsky.social
Energy Metabolism and Immune Signatures in ME/CFS: What the Latest Paper Means for Kids and Families

danilobuonsenso.substack.com/p/abnormal-e...
Abnormal Energy Metabolism and Immune Signatures in ME/CFS: What the Latest Paper Means for Kids and Families
Chronic fatigue syndrome (ME/CFS) remains one of the most puzzling, debilitating disorders in medicine — especially when it affects children and adolescents.
danilobuonsenso.substack.com
January 4, 2026 at 3:14 PM
buonsenso.bsky.social
Long COVID, Immune Dysregulation & What It Means for Kids — New Insights and Future Therapies

danilobuonsenso.substack.com/p/long-covid...
Long COVID, Immune Dysregulation & What It Means for Kids — New Insights and Future Therapies
Long COVID isn’t just a collection of lingering symptoms — it may reflect deep changes in the immune system that can persist for years.
danilobuonsenso.substack.com
December 28, 2025 at 3:21 PM
buonsenso.bsky.social
When I started the #longcovid in kids journey we were literally alone.
Now, we arrived to speak about long covid in children in @TheLancetInfDis Podcast!❤️

MY LONG COVID JOURNEY, WHAT I DO AND WHY IN MY BOOK: tinyurl.com/4tsvhwat

🔊 Spotify: bit.ly/4p7jnpy
December 22, 2025 at 1:57 PM
buonsenso.bsky.social
You Are Not Alone – Let’s Connect Families, Young People and Communities Living with Long Covid and ME/CFS

danilobuonsenso.substack.com/p/you-are-no...
You Are Not Alone – Let’s Connect Families, Young People and Communities Living with Long Covid and ME/CFS
When a child, teenager, or young adult develops Long Covid or ME/CFS, the world can suddenly become very small.
danilobuonsenso.substack.com
December 14, 2025 at 4:15 PM
buonsenso.bsky.social
a new major study on Nature immunology further reinforces the overwhelming evidence of chronic immune activation in #longcovid, perfectly justifying off label use of immune modulators (eg IVIG) in the most severe cases that cannot access trials.
Saying since a few years in my book

lnkd.in/dPHkH3re
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
December 14, 2025 at 9:06 AM
buonsenso.bsky.social
So the Pediatric Infectious Diseases games are ready to go in 2d!
Impressive amount of different european countries participating this year!
December 9, 2025 at 8:23 PM
buonsenso.bsky.social
When Patients Ask for a Cure: A Doctor’s Honest Reflection on Long Covid and ME/CFS

danilobuonsenso.substack.com/p/when-patie...
When Patients Ask for a Cure: A Doctor’s Honest Reflection on Long Covid and ME/CFS
In the past months, my inbox (and whatsapp!) has filled with messages from patients and families living with Long Covid or ME/CFS.
danilobuonsenso.substack.com
December 7, 2025 at 5:23 PM
buonsenso.bsky.social
Oxaloacetate, long COVID and ME/CFS: what the new trial shows — and a pragmatic (non-prescriptive) scheme for clinicians

danilobuonsenso.substack.com/p/oxaloaceta...
Oxaloacetate, long COVID and ME/CFS: what the new trial shows — and a pragmatic (non-prescriptive) scheme for clinicians
Fatigue and cognitive fog remain among the most disabling complaints for people with long COVID and with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
danilobuonsenso.substack.com
November 30, 2025 at 5:16 PM
buonsenso.bsky.social
with the only and one!!
daniellebeckman.bsky.social Danielle Beckman @daniellebeckman.bsky.social · Nov 21
Finally met @buonsenso.bsky.social in person and got an update from one of the best researchers in #LongCovidKids. Kids with hypometabolism in the orbitofrontal cortex, the same region of the brain where I see the virus in the🔬. It is not even fully developed until we reach 25 years old..
November 23, 2025 at 3:25 PM
buonsenso.bsky.social
Low-Dose Rapamycin for ME/CFS and Long COVID: New Clinical Data, Promising Hints, and Ongoing Caution

danilobuonsenso.substack.com/p/low-dose-r...
Low-Dose Rapamycin for ME/CFS and Long COVID: New Clinical Data, Promising Hints, and Ongoing Caution
Over the past months, I have written several posts exploring the potential role of low-dose rapamycin in Long COVID and ME/CFS (Part 1, Part 2, Part 3).
danilobuonsenso.substack.com
November 23, 2025 at 3:25 PM
buonsenso.bsky.social
What’s new in the Long COVID / ME/CFS endothelial story — and what that means for treatment

danilobuonsenso.substack.com/p/whats-new-...
What’s new in the Long COVID / ME/CFS endothelial story — and what that means for treatment
You may remember that in earlier posts we discussed how both Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) appear to share a key feature: endothelial inflammation/dysfunct...
danilobuonsenso.substack.com
November 16, 2025 at 3:10 PM
buonsenso.bsky.social
you’ll read several success papers about #nirsevimab and #RSV but to make it a successful and long term sustainable interventions you need to read also of out chorus provocative voices, like this one !

rdcu.be/ePXTa
November 14, 2025 at 6:45 PM
buonsenso.bsky.social
Long COVID and the AMPA Pathway: New Clues from Brain Imaging

danilobuonsenso.substack.com/p/long-covid...
Long COVID and the AMPA Pathway: New Clues from Brain Imaging
Over the past few years, Long COVID has become one of the most puzzling and impactful conditions in post-viral medicine — especially for the many children and adults who continue to experience “brain ...
danilobuonsenso.substack.com
November 9, 2025 at 4:57 PM
buonsenso.bsky.social
Conversations on IVIG and Monoclonals in #LongCovid #MECFS

danilobuonsenso.substack.com/p/conversati...
Conversations on IVIG and Monoclonals
A recording from MD, PhD's live video
danilobuonsenso.substack.com
November 3, 2025 at 4:00 PM
buonsenso.bsky.social
new on covid impact on kids

www.tandfonline.com/eprint/ZY2VI...
The second-order effects that the COVID-19 pandemic has had on pediatric populations
SARS-CoV-2 can have long-term health consequences that persist beyond acute infection. While this is evident in adults and the elderly, the impact on children and adolescents remains under recogniz...
www.tandfonline.com
November 1, 2025 at 8:01 AM
Reposted by Danilo Buonsenso
torres-amy.bsky.social
The latest from @buonsenso.bsky.social rings so true:

Yet when patients and families ask for treatments, the answer is almost always: “There are no approved options.”

open.substack.com/pub/danilobu...

#PedSky
#LongCovidKids
#pwLC
#pwME
When There Are No Treatments: Why Off-Label Drugs Should Be on the Table for Long Covid and ME/CFS
What Does “Off-Label” Really Mean?
open.substack.com
October 26, 2025 at 2:58 PM
buonsenso.bsky.social
glad our team contributed to another very important study on iGAS.
PEGASUS network

www.sciencedirect.com/science/arti...
Paediatric invasive group A streptococcal infections and associations with viral infections in 15 European countries after lifting non-pharmaceutical interventions against SARS-CoV-2: an interrupted t...
After lifting non-pharmaceutical interventions (NPIs) against the transmission of SARS-CoV-2, various countries experienced an increase in invasive Gr…
www.sciencedirect.com
October 22, 2025 at 1:17 PM
buonsenso.bsky.social
“We Can’t Do This Alone”: A Doctor’s Plea for Support in Caring for Long COVID and ME/CFS Patients

danilobuonsenso.substack.com/p/we-cant-do...
“We Can’t Do This Alone”: A Doctor’s Plea for Support in Caring for Long COVID and ME/CFS Patients
As a pediatrician and infectious disease specialist, my days are full.
danilobuonsenso.substack.com
October 19, 2025 at 1:50 PM
buonsenso.bsky.social
again viruses and dementia.
those of you negating this slow science progression and patients prevention options.

all started w #LongCovid revolution. years ago I said LC is clearly giving this indication and now science is confirming

all in my book: tinyurl.com/4tsvhwat
October 15, 2025 at 8:44 AM