Citizens for Alternatives to Animal Research and Experimentation
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caare.bsky.social
Citizens for Alternatives to Animal Research and Experimentation
@caare.bsky.social
64 followers 15 following 250 posts
CAARE is a national non-profit 501(c)3 organization dedicated to sparing animal suffering by promoting research and testing without animals.
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caare.bsky.social
Emory University used human-based research to show how estradiol shifts brain activity after trauma, revealing hormone-brain pathways tied to women’s stress responses.
Ovarian Hormone Shapes How the Brain Responds After Trauma
The ovarian hormone estradiol plays a key role in shaping how the brain responds to perceived threats after trauma in women with PTSD.
www.technologynetworks.com
January 28, 2026 at 1:25 PM
caare.bsky.social
Human-based research from Marcus Institute for Aging Research shows memory decline accelerates with widespread brain changes, reshaping understanding of cognitive aging.
Massive brain study reveals why memory loss can suddenly speed up with age
A massive international brain study has revealed that memory decline with age isn’t driven by a single brain region or gene, but by widespread structural changes across the brain that build up over…
www.sciencedaily.com
January 27, 2026 at 1:09 PM
caare.bsky.social
EPA will phase out mammal testing by 2035, advancing faster, human-relevant methods and reducing the cruelty long embedded in chemical safety assessments.
www.nytimes.com/2026/01/22/c...
E.P.A. Promises a Ban on Animal Testing by 2035
www.nytimes.com
January 26, 2026 at 12:39 PM
caare.bsky.social
In animal-free research, Hebrew University showed that non-invasive brain stimulation improved attention in children with ADHD, providing lasting effects and without drugs.
www.technologynetworks.com/neuroscience...
No Medication – Just Brain Stimulation – Improved ADHD Attention
Researchers identified abnormal background brain activity as a measurable marker of ADHD. In a randomized trial, non-invasive brain stimulation reduced this neural “noise” in children and improved att...
www.technologynetworks.com
January 23, 2026 at 1:03 PM
caare.bsky.social
A cow using a tool shows striking intelligence. CAARE says expanding our understanding reveals how sentient animals are — and why using them in painful experiments is indefensible. www.sciencenews.org/article/tool...
This tool-using cow defies expectations for bovine braininess
Veronika the cow uses a brush as a tool to scratch herself, revealing rare problem-solving skills and expanding what we know of tool use in animals.
www.sciencenews.org
January 22, 2026 at 12:20 PM
caare.bsky.social
Shanghai Jiao Tong University used human brain imaging to predict depression-treatment response, showing how human-based research improves treatment outcomes.
www.sciencedaily.com/releases/202...
Brain scans may finally end the guesswork in depression treatment
Researchers compared a traditional Chinese medicine, Yueju Pill, with a standard antidepressant and found both reduced depression symptoms. However, only Yueju Pill increased a brain-supporting protei...
www.sciencedaily.com
January 21, 2026 at 1:28 PM
caare.bsky.social
U of Surrey and Univ College London used human immune-cell data with AI to reveal how antibodies assemble, driving more effective and animal-free therapeutic discovery.
www.technologynetworks.com/informatics/...
Antibody-Specific AI Model Could Accelerate Therapeutic Discovery
Researchers developed an AI antibody model that accurately predicts heavy and light chain pairing, challenging long-held assumptions and advancing therapeutic design.
www.technologynetworks.com
January 20, 2026 at 1:12 PM
caare.bsky.social
Scientists at Michigan State created human mini-hearts to model A-fib, showing how inflammation triggers arrhythmia and providing an animal-free model to test treatments.
studyfinds.org/lab-grown-mi...
Scientists Create Lab-Grown Mini-Hearts That Develop Atrial Fibrillation
Lab-grown hearts with immune cells develop atrial fibrillation after chronic inflammation, offering a new way to test treatments.
studyfinds.org
January 19, 2026 at 2:20 PM
caare.bsky.social
Animal-free heart organoids reveal how the tire chemical 6PPD disrupts cardiac function, demonstrating human-relevant toxicity risks.
m.dongascience.com/en/news/75739
Heart organoids reveal cardiotoxicity of common tire additive
A new method using mini-organs has been presented to identify changes in human heart tissue caused by tire-derived pollutants. This is regarded as a novel human physiology-based research model for ass
m.dongascience.com
January 16, 2026 at 12:31 PM
caare.bsky.social
CAARE exposed 25 years of suffering at UMB. Baby baboons endure dangerous, pointless procedures. Boo’s trauma shows the cruelty. Raise your voice—tell UMB to end these experiments. www.caareusa.org/baboon_babie...
January 15, 2026 at 12:34 PM
caare.bsky.social
MIT has created a computational brain model that mimics neural activity and offers a humane method for studying human cognition without flawed animal tests.
www.technologynetworks.com/informatics/...
Computational Model of the Brain Matches Animals in Learning
A new ‘biomimetic’ model of brain circuits and function at multiple scales produced naturalistic dynamics and learning, and even identified curious behavior by some neurons that had gone unnoticed in ...
www.technologynetworks.com
January 14, 2026 at 12:33 PM
caare.bsky.social
ETH Zurich & Nagoya U. developed a technique to watch flu viruses enter human cells in real time, without using animals and improving antiviral drug testing accuracy.
www.eara.eu/post/new-met...
New method captures flu virus surfing human cells in real-time
Scientists in Switzerland and Japan have captured, in real time and high resolution, the exact moment a flu virus enters a living human cell.
www.eara.eu
January 13, 2026 at 12:15 PM
caare.bsky.social
Johns Hopkins used brain organoids from patients’ cells to identify biomarkers for schizophrenia and bipolar disorder, enabling accurate diagnosis and personalized treatment.
www.sciencedaily.com/releases/202...
Mini brains reveal clear brain signals of schizophrenia and bipolar disorder
Tiny lab-grown brains are offering an unprecedented look at how schizophrenia and bipolar disorder disrupt neural activity. Researchers found distinct electrical firing patterns that could identify th...
www.sciencedaily.com
January 12, 2026 at 12:15 PM
caare.bsky.social
Indiana University researchers found sex-based differences in multiple myeloma by analyzing human cells, improving potential treatments without animal tests.
www.technologynetworks.com/cancer-resea...
Multiple Myeloma Develops Differently in Men and Women
Researchers have uncovered differences in how multiple myeloma develops and progresses in men and in women, which could lead to earlier detection and sex-specific treatments.
www.technologynetworks.com
January 9, 2026 at 1:17 PM
caare.bsky.social
Human lung-on-a-chip built from a single donor’s stem cells mimics breathing and infection, enabling personalized lung research, unobtainable through animal testing. medicalxpress.com/news/2025-12...
First breathing 'lung-on-chip' developed using genetically identical cells
Researchers at the Francis Crick Institute and AlveoliX have developed the first human lung-on-chip model using stem cells taken from only one person. These chips simulate breathing motions and lung d...
medicalxpress.com
January 8, 2026 at 11:49 AM
caare.bsky.social
Korean scientists at KAIST have advanced human intestinal stem cell regeneration using an animal-free culture, improving safety and scientific reliability.
www.news-medical.net/news/2025123...
Advancing stem cell regeneration through animal-free culture systems
Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection...
www.news-medical.net
January 7, 2026 at 12:14 PM
caare.bsky.social
University of Navarra mapped how cancer genes interact using human data, advancing ethical, human-based cancer research without outdated animal testing.
www.technologynetworks.com/proteomics/n...
Scientists Built a Map of How Cancer Genes Talk to Each Other
Researchers developed RNACOREX, an open-source tool that maps gene regulation networks by analyzing miRNA–mRNA interactions. Validated across 13 cancer types using TCGA data, the software predicts pat...
www.technologynetworks.com
January 6, 2026 at 12:36 PM
caare.bsky.social
Studying human placental tissue and not animals, scientists at Flinders University found that placental aging, indicated by circular RNAs, may be a cause of stillbirths.
www.technologynetworks.com/proteomics/n...
The Placenta Can Age Too Quickly During Pregnancy
Researchers found that placentas in stillbirth cases show signs of accelerated biological aging driven by circular RNAs. These molecules damage DNA, impair placental function and can be detected in ma...
www.technologynetworks.com
January 5, 2026 at 12:13 PM
caare.bsky.social
UBC researchers studied human cell lines to show CBD and THC slow ovarian cancer cell growth and migration, highlighting animal-free approaches to studying cancer.
www.sciencedaily.com/releases/202...
Cannabis compounds show unexpected power against ovarian cancer
Scientists have discovered that key compounds from cannabis—CBD and THC—show surprisingly strong effects against ovarian cancer cells. Used together, they slow cell growth, reduce colony formation, an...
www.sciencedaily.com
December 31, 2025 at 1:18 PM
caare.bsky.social
TU Wien and Medical University of Vienna use 3D bioprinting to create human skin models for studying inflammatory diseases without cruel and flawed animal testing. medicalxpress.com/news/2025-12...
3D bioprinting offers alternative to animal testing for skin disease research
At TU Wien, researchers are developing three-dimensional (3D) printing techniques that can be used to create living biological tissue—for example, to study skin diseases.
medicalxpress.com
December 30, 2025 at 4:04 PM
caare.bsky.social
Without using animals, Italian Institute of Technology researchers used AI to design a molecule that boosts chemotherapy response in pancreatic cancer. www.technologynetworks.com/proteomics/n...
AI-Designed Molecule Boosts Chemotherapy Response in Pancreatic Cancer
Researchers at the Italian Institute of Technology developed an AI-designed aptamer that disrupts DNA repair in pancreatic cancer cells. The molecule, Apt1, increases tumor sensitivity to chemotherapy...
www.technologynetworks.com
December 29, 2025 at 1:41 PM
caare.bsky.social
Universität Leipzig researchers studied human patients to show GRIN2A gene variants directly caused psychiatric illness, highlighting human-based science over animal tests.
www.sciencedaily.com/releases/202...
Scientists discover first gene proven to directly cause mental illness
Scientists have discovered that a single gene, GRIN2A, can directly cause mental illness—something previously thought to stem only from many genes acting together. People with certain variants of this...
www.sciencedaily.com
December 26, 2025 at 11:29 AM
caare.bsky.social
King’s College London linked polyphenol-rich diets to better heart health using human data, showing human research can generate insights for disease prevention.
www.sciencedaily.com/releases/202...
Scientists reveal a powerful heart boost hidden in everyday foods
Regular consumption of polyphenol-rich foods like tea, coffee, berries, nuts, and whole grains may significantly support long-term heart health. A decade-long study of more than 3,100 adults found tha...
www.sciencedaily.com
December 26, 2025 at 11:29 AM
caare.bsky.social
Human research by the Psychiatric Genomics Consortium showed 5 genetic clusters explain risk for psychiatric disorders, guiding more accurate treatments than animal tests. www.technologynetworks.com/genomics/new...
Five Genetic Clusters Explain Over Half of All Psychiatric Risk
A massive genomic study of over 1 million cases found that shared risk across 14 psychiatric disorders is reduced to 5 underlying genetic factors. Researchers linked each factor to specific brain cell...
www.technologynetworks.com
December 24, 2025 at 1:36 PM
caare.bsky.social
Cornell researchers show how lab housing constrains mouse behavior. Given space and choice outdoors, mice explored, decided, and engaged with their world.
phys.org/news/2025-12...
From cages to fields: Lab mice lose their anxiety after a week outdoors
When postdoctoral researcher Matthew Zipple releases lab mice into a large, enclosed field just off Cornell's campus, something remarkable happens.
phys.org
December 22, 2025 at 2:12 PM