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Camilla Nord @camillanord.bsky.social · 17d

What drives the bidirectional relationship between metabolic and mental ill-health?

Read our new metabolic psychiatry paper, “An interoceptive model of energy allostasis linking metabolic and mental health” www.science.org/doi/10.1126/... led by @saramehrhof.bsky.social @hugofleming.bsky.social

An interoceptive model of energy allostasis linking metabolic and mental health

Interactions between metabolic interoception and regulation may drive comorbidity between mental and metabolic ill-health.

www.science.org

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Reposted by Camilla Nord

xavier roberts-gaal @xrg.bsky.social · 27d

We often hear from reviewers: "what about demand effects?" So we developed a method to eliminate them. Something weird happened during testing: We couldn’t detect demand effects in the first place! (1/8)

Summary of design and results from our three studies. (A: Design) Each study used a similar experimental design, measuring both positive and negative demand in an online experiment, with three commonly-used task types (dictator game, vignette, intervention). Our experiments had ns ≈ 250 per cell. (B: Results) Observed demand effects were statistically indistinguishable from zero. The plot shows means and 95% confidence intervals for standardized mean differences derived from frequentist analyses of each experiment and an inverse variance-weighted fixed-effect estimator pooling all experiments (solid bars). Prior measurements of experimenter demand from a previous dictator game experiment (de Quidt et al., 2018; standardized mean difference from regression coefficient) and a meta-analysis primarily including small-sample, in-person studies (Coles et al., 2025; Hedge’s g statistic) are also shown for comparison (striped bars). The main text includes Bayesian analyses that quantify our uncertainty.

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Reposted by Camilla Nord

Lukas Gunschera @lukasgunschera.com · Jul 15

Brilliant work by @saramehrhof.bsky.social on shared neurocognitive signatures of psychiatric and metabolic disorder at #cpconf2025

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Reposted by Camilla Nord

Edwin Dalmaijer @dalmaijer.bsky.social · Jul 4

New preprint! People vary in healthy food preferences, with some veering towards obsessive. We found #orthorexia associated with disgust-like facial responses to unhealthy foods. BUT: also with appetitive stomach responses! Is it an interoceptive self-control mechanism? doi.org/10.1101/2025... (1/7)

Orthorexia is associated with a paradoxical appetitive gastric response to unhealthy foods

Orthorexia involves an obsessive tendency towards "healthy" foods. It is a risk factor for eating disorders (anorexia nervosa and the proposed "orthorexia nervosa") and psychological distress, but its...

doi.org

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Reposted by Camilla Nord

Alex Pike @alexandrapike.bsky.social · Jun 29

Finally, the amazing Professor Camilla Nord presents on interoception - including some cool lived experience work on body sensations, and work on disgust and gastric rhythms, alongside work on energy conservation. #BAP2025

Camilla presenting on all of the exciting implications of her interoception work!

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Reposted by Camilla Nord

Alex Pike @alexandrapike.bsky.social · Jun 29

It’s #BAP2025 time! Kicking us off is Dr Megan Jackson, the winner of the junior non-clinical award talking about animal models of apathy and motivation. Key quote: ‘as scientists, we love a tight error bar’. @bapsych.bsky.social

Image of Megan Jackson presenting slides validating a novel apathy task

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Camilla Nord @camillanord.bsky.social · Jun 29

Today at #BAP2025 we heard from both lived-experience and pharmacology experts that clozapine,“Britain’s most dangerous drug” is lifesaving for people with treatment-resistance— with current thresholds for discontinuation racially unequal (some people have naturally lower but safe neutrophil levels)

Newspaper articles including the headline “Britain’s most dangerous prescription drug”

Shows how some ethnicities have benign neutropaenia, which is not a risk factor itself but can lead to treatment cessation or burden of extra tests

Summary that clozapine is underused and life-saving, despite known risks

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Reposted by Camilla Nord

The TLS @thetls.bsky.social · Jun 19

'Mental health diagnoses are not just misapplied, but invented.'

Camilla Nord on the mental illness epidemic

Are you hurting?

www.the-tls.com

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Reposted by Camilla Nord

The TLS @thetls.bsky.social · Jun 18

Summer Books 2025; the mental illness epidemic; teen-centric novels; mass protest in the modern era; a philosophy of eating – and much more

www.the-tls.co.uk/issues/cu...

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Reposted by Camilla Nord

Leah Banellis @leahbanellis.bsky.social · Jun 20

I'm so grateful to write my first magazine article with
Psyche Magazine! psyche.co/ideas/how-mu...
It features our preprint on 🫁 'Body-Wandering' 🫀 with invaluable guidance from
@micahgallen.com and @themindwanders.bsky.social
: biorxiv.org/content/10.1...

biorxiv.org

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Camilla Nord @camillanord.bsky.social · Jun 18

sick!! (by all definitions)

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Reposted by Camilla Nord

Micah G. Allen @micahgallen.com · Jun 18

My favorite genre of horrifying but fascinating interoception research - Modification of Human Gastric Acid Secretion with Operant-Conditioning Procedures - Whitehead et al, 1975

onlinelibrary.wiley.com/doi/epdf/10....

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Reposted by Camilla Nord

Harry Costello @drharrycostello.bsky.social · Jun 13

🚨 New paper out in JAMAPsych:

🦣 project led by the brilliant @anahitm.bsky.social & @docqhuys.bsky.social ’ group.

Our meta-analysis found that #dopamine & #serotonin have distinct effects on reinforcement learning.

A step toward biomarker guided treatment?

jamanetwork.com/journals/jam...

Dopamine and Serotonin in Reward and Punishment Processes in Humans

This systematic review and meta-analysis compares the association of dopamine and serotonin in reinforcement learning.

jamanetwork.com

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Reposted by Camilla Nord

Nils Kroemer @nbkroemer.bsky.social · Jun 16

There is also good news embedded in the report. We find that taVNS briefly purturbs the correlation of the pupil dilation trace of the left and the right eye. This novel marker is not as strongly associated with sensory ratings. But it makes sense since we stimulate one side of the vagus.

Nils Kroemer @nbkroemer.bsky.social · Jun 16

Pulsed taVNS elicits pupil dilation. However, if sham feels as intense, there is not much left. Based on our comparatively large sample (94 participants, single-blind crossover), we show that a highly variable sham response explains this.
#neuroskyence 🩺
www.biorxiv.org/content/10.1...

A plot showing that taVNS does not induce larger pupil dilation compared to sham.

A plot showing that sham-induced pupil dilation is much more variable

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Reposted by Camilla Nord

Lydia Hickman @lydiajhickman.bsky.social · Jun 16

My new paper with Jennifer Cook sets out potential reasons for high rates of Parkinson's disease (PD) diagnosis in the autistic population: www.sciencedirect.com/science/arti... @mrccbu.bsky.social @thechbh.bsky.social 🧵1/n