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Marcus Kaiser

@connectomelab.bsky.social

740 followers 290 following 42 posts

Leader neuroinformatics.org.uk | Computational Psychiatry | Computational Neurology | Author of 'Changing Connectomes' https://mitpress.mit.edu/9780262044615/ https://www.dynamic-connectome.org/

mitpress.mit.edu

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Marcus Kaiser @connectomelab.bsky.social · Mar 14

My Brainbox webinar talk that I gave yesterday on Focused Ultrasound Neuromodulation is now online:
www.youtube.com/watch?v=vJ3E...

@brainbox-neuro.bsky.social

Changing Connectomes: Improved Cognition Through Focused Ultrasound Neuromodulation

YouTube video by Brainbox Ltd

www.youtube.com

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Marcus Kaiser @connectomelab.bsky.social · 2d

Join us as PhD student using noninvasive ultrasound neuromodulation on the project 'Reducing pain reactivity for children in the Emergency Department using non-invasive vagal nerve stimulation'

Find more information at midlandsmhndtp.ac.uk/applications...

#ultrasound #neuromodulation #Zenbud

2026 Projects - Midlands Mental Health and Neurosciences PhD Programme

midlandsmhndtp.ac.uk

Marcus Kaiser @connectomelab.bsky.social · 13d

Good to see so many Nottingham researchers at the @brainbox-init.bsky.social neuromodulation meeting!

A great meeting with ideas that we can bring home to our N3 neurotechnology centre
www.nottingham.ac.uk/news/centre-...

#tus #tms #tacs

Marcus Kaiser @connectomelab.bsky.social · 19d

It is not about particular countries but more that number of patents is not really linked to number of companies/employees

Marcus Kaiser @connectomelab.bsky.social · 26d

New: Zenbud ultrasound vagus nerve stimulation sham device cannot be distinguished from active device
www.mdpi.com/2076-3425/15...

We are now performing sham-controlled studies to observe cognitive and physiological effects...

#ultrasound #vagusnerve #neuromodulation

@mdpiopenaccess.bsky.social

Marcus Kaiser @connectomelab.bsky.social · Aug 20

Interesting to see that the UK is number 2 worldwide (after the USA) in terms of consumer neurotech employment, number of companies, and funding deals...

From Peter Schlecht's neurotech report at gppi.net/assets/Hensi...

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Marcus Kaiser @connectomelab.bsky.social · Aug 18

yes, this is does not go through the skull: it just reaches branches of the vagus nerve around the ear

Marcus Kaiser @connectomelab.bsky.social · Aug 18

Great to see that the next generation of NeurGear's Zenbud ultrasound vagus nerve stimulator is now on sale!

First results show reductions in anxiety (neuro.jmir.org/2025/1/e69770 ).

Find out more about the device here:
zenbud.health/pages/anxiety

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Reposted by Marcus Kaiser

Rodrigo Braga @rodbraga.bsky.social · Aug 5

🚨 New Preprint 🚨

Targeting intracranial electrical stimulation (ES) to network regions defined within individuals causes network-level effects

By Cyr et al.

***
Q: Can we use individualized network maps from precision fMRI to modulate a targeted network via intracranial ES?

A: Yes!

🧵:

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Marcus Kaiser @connectomelab.bsky.social · Aug 2

You need to be registered healthcare practitioner in the UK. If so, you can contact the programme manager Roxanne for the application form. The deadline is this Tuesday.

Marcus Kaiser @connectomelab.bsky.social · Jul 3

Are you a registered healthcare professional searching for a PhD position?

Using Zenbud #ultrasound #vagusnerve stimulation, the PhD position with me and Ben Marson is about 'Reducing pain reactivity for children in Emergency Departments'

midlandsmhndtp.ac.uk/uon-students...

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Marcus Kaiser @connectomelab.bsky.social · Jun 9

We attended the London Great Exhibition Road festival over the weekend and 250+ people tried our Zenbud vagus nerve stimulation device!

One person suffering from anxiety/depression even came back on day 2 bringing a friend...

www.zenbud.health

#ultrasound #neuromodulation #vagusnerve
#ExRdFest

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Marcus Kaiser @connectomelab.bsky.social · May 9

Our N3 Centre for Neurotechnology, Neuromodulation, and Neurotherapeutics has officially launched at @uniofnottingham.bsky.social

#neuromodulation #imaging #focusedultrasound @fusfoundation.bsky.social

www.nottingham.ac.uk/news/centre-...

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Marcus Kaiser @connectomelab.bsky.social · Apr 25

30 April deadline approaching!

Last chance to apply...

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Marcus Kaiser @connectomelab.bsky.social · Apr 3

Last chance to apply! Deadline: Monday 7 April...

Marcus Kaiser @connectomelab.bsky.social · Mar 11

Postdoctoral fellowship on developing human closed-loop noninvasive ultrasound and magnetic stimulation is now available!

Find out more and apply here:
jobs.nottingham.ac.uk/Vacancy.aspx...

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Marcus Kaiser @connectomelab.bsky.social · Mar 21

Nice comparison of ultrasound and temporal interference stimulation in Table 3:
www.mrcbndu.ox.ac.uk/sites/defaul...

Ultrasound blinding option that is not mentioned is ventricle stimulation: doi.org/10.1016/j.br...

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Marcus Kaiser @connectomelab.bsky.social · Mar 20

Join our lab for a year with the 'AI for Precision Neuromodulation' fellowship project!

Find out more at: encode.pillar.vc/projects/neu...

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Marcus Kaiser @connectomelab.bsky.social · Mar 14

My Brainbox webinar talk that I gave yesterday on Focused Ultrasound Neuromodulation is now online:
www.youtube.com/watch?v=vJ3E...

@brainbox-neuro.bsky.social

Changing Connectomes: Improved Cognition Through Focused Ultrasound Neuromodulation

YouTube video by Brainbox Ltd

www.youtube.com

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Marcus Kaiser @connectomelab.bsky.social · Mar 11

Postdoctoral fellowship on developing human closed-loop noninvasive ultrasound and magnetic stimulation is now available!

Find out more and apply here:
jobs.nottingham.ac.uk/Vacancy.aspx...

Marcus Kaiser @connectomelab.bsky.social · Mar 7

In conclusion, our investigation in a high-powered awake non-human primate dataset shows that some FUS effects across the network last for an hour, maybe longer.

This approach could be translated to humans by using several acquisitions per subject or longer sequences.
doi.org/10.1016/j.cr...

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Redirecting

doi.org

Marcus Kaiser @connectomelab.bsky.social · Mar 7

Conversely, brain metrics related to activity (fALFF) and signal homogeneity (ReHo) are altered for much longer: Going outside our time window of 100 minutes.

doi.org/10.1016/j.cr...

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Marcus Kaiser @connectomelab.bsky.social · Mar 7

We demonstrated that brain connectivity between the target and the rest of the brain was mostly changed for around 1h following the ultrasound
stimulation.

doi.org/10.1016/j.cr...

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Marcus Kaiser @connectomelab.bsky.social · Mar 7

In this article, we present results about one animal who underwent around 50 MRIs, half of which followed ultrasound stimulation of the left anterior part of the hippocampus, a promising target since it is involved in so many brain dysfunctions.

doi.org/10.1016/j.cr...

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Marcus Kaiser @connectomelab.bsky.social · Mar 7

I am very happy to share our latest work, led by C. Atkinson-Clement, C. Petkov, and M. Kaiser, on the temporal dynamics of brain changes following ultrasound stimulation in the rhesus monkey.

A huge thanks to all the team for making this work possible.

doi.org/10.1016/j.cr...

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Marcus Kaiser @connectomelab.bsky.social · Mar 4

short video summary here: www.youtube.com/watch?v=-aeD...

Reposted by Marcus Kaiser

Konrad Kording @kordinglab.bsky.social · Feb 26

If we could record all neurons we still would not know how they communicate: medium.com/@kording/628...

Would recording all neurons reveal their interactions?

For years, I was captivated by the idea that if we could record the activity of every neuron in the brain, we’d eventually crack the code…

medium.com

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