Lightnews — Scholar-powered news

Current Medical Science

@currentmedscience.bsky.social

22 followers 86 following 180 posts

Current Medical Science is a peer-reviewed journal publishing original, innovative & influential insightful reviews, comments, & special topic articles across diverse medical disciplines, including biomedicine, public health, and related fields.

Posts Media Videos Starter Packs

Pinned

Current Medical Science @currentmedscience.bsky.social · Jun 20

Cite Score Alert!

We’re proud to announce that our 2024 #CiteScore is 3.8!
We appreciate our authors, reviewers, readers, and editorial team.

Submit your research to @currentmedscience.bsky.social & be part of our growing journey!

link.springer.com/journal/11596/

#ScienceSky #medsky #academicsky

Current Medical Science @currentmedscience.bsky.social · 11h

This study highlights a high prevalence of #Stroke among #Type2DiabetesMellitus patients in China, emphasizing the importance of analyzing clustered risk factors and refining risk identification strategies for high-risk groups. #medsky

Read more:

Prevalence and Risk Factors of Stroke in Inpatients with Type 2 Diabetes Mellitus in China - Current Medical Science

Objective The prevalence and the cluster characteristics of risk factors of stroke were assessed in a Chinese diabetic population. Methods Clinical data of 30 693 inpatients who were diagnosed with…

link.springer.com

1 1

Current Medical Science @currentmedscience.bsky.social · 1d

This study reveals that low #Selenium and protein levels exacerbate #MyocardialInjury in #KeshanDisease by disrupting the PINK1/Parkin-mediated #Mitochondrial #Autophagy pathway, pointing to novel therapeutic strategies for intervention.

Read more: link.springer.com/article/10.1...

Current Medical Science @currentmedscience.bsky.social · 1d

This study reveals that MMP13 promotes #DVT formation by downregulating Pdpn expression in mice, uncovering a novel pathogenic mechanism that may enhance #ClinicalDiagnosis and inform better management strategies. #medsky

Read more:

Inhibiting MMP13 Attenuates Deep Vein Thrombosis in a Mouse Model by Reducing the Expression of Pdpn - Current Medical Science

Objective Matrix metalloproteinase 13 (MMP13) is an extracellular matrix protease that affects the progression of atherosclerotic plaques and arterial thrombi by degrading collagens, modifying…

link.springer.com

2 1

Current Medical Science @currentmedscience.bsky.social · 2d

This study by @2024HUST examines the accuracy and proficiency of #GPT4.0 on multidimensional Japanese medical practitioner qualification exams, analyzing its response performance & revealing new opportunities for the medical field. #medsky

Read: link.springer.com/article/10.1...

Current Medical Science @currentmedscience.bsky.social · 3d

Using RNA sequencing, researchers identified a novel #lncRNA, AL355974.3, that is upregulated in LGG & GBM, associated with poor prognosis, & may promote #Glioma via the FoxO pathway, highlighting its potential as a #PrognosticBiomarker. #medsky

Read:

Gene Expression Profile Identifies LncRNA AL355974.3 As a Potential Glioma Biomarker - Current Medical Science

Objective Glioma is a central nervous system tumor arising from glial cells. Despite significant advances in diagnosis and treatment, most patients with high-grade gliomas have a poor prognosis. Many…

link.springer.com

Current Medical Science @currentmedscience.bsky.social · 3d

This study shows that prospero homeobox 1 (#Prox1) reduces #CellProliferation and #DrugResistance in #Retinoblastoma (RB) by targeting Notch1, positioning Prox1 as a potential #therapeutic target for RB. #medsky

Read more:

Prox1 Suppresses Proliferation and Drug Resistance of Retinoblastoma Cells via Targeting Notch1 - Current Medical Science

Objective Retinoblastoma (RB) is a prevalent type of eye cancer in youngsters. Prospero homeobox 1 (Prox1) is a homeobox transcriptional repressor and downstream target of the proneural gene that is…

link.springer.com

Current Medical Science @currentmedscience.bsky.social · 4d

This retrospective study investigates early #NeurologicalImpairment (ENI) incidences and their influencing factors in adult #Sepsis patients, providing critical insights for improved #Neurological outcomes and advanced sepsis care. #medsky

Read:

Risk Factors of Enternal Nutrition Intolerance in Septic Patients: A Case-control Study - Current Medical Science

Objective This study aimed to investigate the incidence of enteral nutrition intolerance (ENI) in patients with sepsis and explore potential risk factors. Methods A case-control study was conducted…

link.springer.com

1 2

Current Medical Science @currentmedscience.bsky.social · 5d

This research reveals that knowledge base optimization significantly improves quality, accuracy, and comprehensiveness of #LLM outputs in #Orthopedics, offering clear optimization strategies. #MedicalAI #medsky

Read more:

Enhancing Orthopedic Knowledge Assessments: The Performance of Specialized Generative Language Model Optimization - Current Medical Science

Objective This study aimed to evaluate and compare the effectiveness of knowledge base-optimized and unoptimized large language models (LLMs) in the field of orthopedics to explore optimization…

link.springer.com

Current Medical Science @currentmedscience.bsky.social · 5d

This review advocates for hospitals to adopt multidimensional early warning #technologies to analyze #MedicalData and build institution-specific models for #InfectiousDiseases, thereby boosting social and #EconomicBenefits. #medsky

To read:

Identification of Early Warning Signals of Infectious Diseases in Hospitals by Integrating Clinical Treatment and Disease Prevention - Current Medical Science

The global incidence of infectious diseases has increased in recent years, posing a significant threat to human health. Hospitals typically serve as frontline institutions for detecting infectious…

link.springer.com

Current Medical Science @currentmedscience.bsky.social · 6d

This research found that low Hb, ALB, & PLT levels and elevated IL-1β are independent risk factors for poor prognosis in #PediatricSepsis, highlighting the value of early detection to improve outcomes. #ClinicalResearch #medsky

Read more:

Characteristics and Risk Factors for Pediatric Sepsis - Current Medical Science

Objective Sepsis is considered a major cause of health loss in children and had high mortality and morbidity. Currently, there is no reliable model for predicting the prognosis of pediatric patients…

link.springer.com

Current Medical Science @currentmedscience.bsky.social · 7d

This study investigates the #therapeutic potential of #intravaginal Erhuang suppositories, which regulate #Immune responses and inhibit #Proteasome activity, offering promising avenues for targeting high-risk #HumanPapillomavirus. #medsky

To read:

Traditional Chinese Medicine Erhuang Suppository for Treatment of Persistent High-risk Human Papillomavirus Infection and Its Impact on Transcriptome of Uterine Cervix - Current Medical Science

Objective High-risk human papillomavirus (HR-HPV) infection is the chief cause of cervical intraepithelial neoplasia (CIN) and cervical carcinoma. The Erhuang suppository (EHS) is a traditional…

link.springer.com

Current Medical Science @currentmedscience.bsky.social · 7d

This study offers a cell cycle-related #lncRNA-based prognostic #Nomogram model that improves risk prediction in #HCC patients, paving the way for novel #Immunotherapy strategies. #medsky

Read more:

Objective Hepatocellular carcinoma (HCC) presents substantial genetic and phenotypic diversity, making it challenging to predict patient outcomes. There is a clear need for novel biomarkers to better…

link.springer.com

Current Medical Science @currentmedscience.bsky.social · 8d

This study reveals that #lncRNA #Maternally expressed gene 3 (MEG3) suppresses #EpithelialMesenchymalTransition by modulating #Ecadherin via Snail/#MAPK regulation, positioning MEG3 as a potential #therapeutic target for #BladderCancer. #medsky

To read:

LncRNA MEG3 Inhibits the Epithelial-mesenchymal Transition of Bladder Cancer Cells through the Snail/E-cadherin Axis - Current Medical Science

Objective This study aimed to investigate the role of the long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3) in the epithelial-mesenchymal transition (EMT) of bladder cancer cells and the…

link.springer.com

Current Medical Science @currentmedscience.bsky.social · 8d

This study identifies #BCL6 suppression as a promising strategy to reduce #Tfhcell differentiation, attenuate #IgE secretion, and mitigate #AirwayInflammation, thereby highlighting its therapeutic potential in #Asthma. #medsky

Read more: link.springer.com/article/10.1...

Current Medical Science @currentmedscience.bsky.social · 13d

This study highlights the mechanism of circ-Astn1 overexpression in protecting high glucose damage via the miR-138-5p/SIRT1 axis in #DiabeticRetinopathy. #medsky
#OpenAccess:
doi.org/10.1007/s115...

Current Medical Science @currentmedscience.bsky.social · 14d

This research reveals that #Salidroside can boost the effectiveness of #Paclitaxel in non-small cell #LungCancer by regulating the Wnt/β-catenin signaling pathway, suggesting a potential combinatorial #therapeutic strategy. #medsky
Read:
link.springer.com/article/10.1...

Current Medical Science @currentmedscience.bsky.social · 15d

This study demonstrates that 3-BrPA enhances the anti-tumor effect of embolization, leading to more complete tumor necrosis and representing a promising combination therapy for liver cancer. #CancerTherapy #LiverCancer #medsky
Read:
doi.org/10.1007/s115...

Current Medical Science @currentmedscience.bsky.social · 16d

This research highlights the vital role of #ferroptosis in #HepatocellularCarcinoma (HCC) and presents GRINA inhibition, which induces #mitochondrial damage and ferroptosis in HCC, as a novel #therapeutic approach. #medsky
To read:
link.springer.com/article/10.1...

Current Medical Science @currentmedscience.bsky.social · 17d

This research explores the potential of the UCRT frame technique for effective closed reduction in complex pelvic injuries, demonstrating promising clinical outcomes. #PelvicFractures #HipJointReplacement #medsky
Read:
doi.org/10.1007/s115...

Current Medical Science @currentmedscience.bsky.social · 18d

This study advocates for early intervention and tailored prevention strategies for severe mental disorders in children and adolescents to mitigate the impact on their psychological well-being and development. #YouthMentalHealth #MentalHealth #medsky
Read:
link.springer.com/article/10.1...

Current Medical Science @currentmedscience.bsky.social · 20d

This study highlights zinc finger protein 554 (ZNF554) as a #Tumor suppressor by regulating the RBM5/WNT/β-catenin pathway in uterine corpus #EndometrialCarcinoma (UCEC), positioning ZNF554 as a novel #therapeutic target for UCEC. #medsky
Read:
link.springer.com/article/10.1...

Current Medical Science @currentmedscience.bsky.social · 20d

Today, on #WorldAlzheimersDay, we at @cmedicalscience commit ourselves to raise awareness, end misconceptions, and promote social support for individuals living with #Alzheimersdisease.
Let’s salute the dedication of researchers fighting #memoryloss.

link.springer.com/journal/11596

Current Medical Science @currentmedscience.bsky.social · 21d

This review explores recent advances in deep learning for fracture diagnosis and outlines future directions in orthopedic practice. #medsky
Read here:
link.springer.com/article/10.1...

Current Medical Science @currentmedscience.bsky.social · 22d

This study shows that low #Mitofusin-2 expression in #HepatocellularCarcinoma (HCC) promotes #NuclearTranslocation of β-catenin via the EMT pathway, leading to #DrugResistance, uncovering new avenues in treating #Sorafenib-resistant HCC. #medsky
See:
link.springer.com/article/10.1...

Current Medical Science @currentmedscience.bsky.social · 23d

This study shows that interfering with miR-17 can significantly reduce #LungFibrosis in #AcuteRespiratoryDistressSyndrome (ARDS) by regulating Mfn2, positioning miR-17 as a #therapeutic target in #ARDS-related lung fibrosis. #medsky
Read:
link.springer.com/article/10.1...