Current Medical Science
@currentmedscience.bsky.social
Current Medical Science is a peer-reviewed journal publishing original, innovative & influential insightful reviews, comments, & special topic articles across diverse medical disciplines, including biomedicine, public health, and related fields.
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Cite Score Alert!
We’re proud to announce that our 2024 #CiteScore is 3.8!
We appreciate our authors, reviewers, readers, and editorial team.
Submit your research to @currentmedscience.bsky.social & be part of our growing journey!
link.springer.com/journal/11596/
#ScienceSky #medsky #academicsky
We’re proud to announce that our 2024 #CiteScore is 3.8!
We appreciate our authors, reviewers, readers, and editorial team.
Submit your research to @currentmedscience.bsky.social & be part of our growing journey!
link.springer.com/journal/11596/
#ScienceSky #medsky #academicsky
KLF4 suppresses HSC activation!
Researchers show #KLF4 maintains quiescence in #HepaticStellateCells by inhibiting proliferation and activation, suggesting it as a potential therapeutic target for preventing and reversing #LiverFibrosis.
Read: doi.org/10.1007/s115...
Researchers show #KLF4 maintains quiescence in #HepaticStellateCells by inhibiting proliferation and activation, suggesting it as a potential therapeutic target for preventing and reversing #LiverFibrosis.
Read: doi.org/10.1007/s115...
February 1, 2026 at 2:00 PM
KLF4 suppresses HSC activation!
Researchers show #KLF4 maintains quiescence in #HepaticStellateCells by inhibiting proliferation and activation, suggesting it as a potential therapeutic target for preventing and reversing #LiverFibrosis.
Read: doi.org/10.1007/s115...
Researchers show #KLF4 maintains quiescence in #HepaticStellateCells by inhibiting proliferation and activation, suggesting it as a potential therapeutic target for preventing and reversing #LiverFibrosis.
Read: doi.org/10.1007/s115...
This study demonstrates that PCED1B-AS1 expression is upregulated in #HepatocellularCarcinoma, exerting an #Oncogenic role by promoting HCC cell proliferation and invasion via the miR-34a/CD44 axis. #Medsky
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
January 31, 2026 at 9:55 AM
This study demonstrates that PCED1B-AS1 expression is upregulated in #HepatocellularCarcinoma, exerting an #Oncogenic role by promoting HCC cell proliferation and invasion via the miR-34a/CD44 axis. #Medsky
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
Elevated #SerumFerritin is strongly associated with #MAFLD and advanced #LiverFibrosis, independent of iron intake; combined with #diabetes, it poses major risk, highlighting #ferritin as a #biomarker and therapeutic target.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 30, 2026 at 1:01 PM
Elevated #SerumFerritin is strongly associated with #MAFLD and advanced #LiverFibrosis, independent of iron intake; combined with #diabetes, it poses major risk, highlighting #ferritin as a #biomarker and therapeutic target.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
An overview of the #Epidemiology, #Etiology, pathological classification, diagnosis, imaging features, treatment, and #Prognosis of IPNB, while highlighting the similarities and differences between conventional and novel subclassifications of IPNBs.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 30, 2026 at 1:55 AM
An overview of the #Epidemiology, #Etiology, pathological classification, diagnosis, imaging features, treatment, and #Prognosis of IPNB, while highlighting the similarities and differences between conventional and novel subclassifications of IPNBs.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This review explores proton‑activated #GPCRs, pH‑sensing receptors that modulate #ImmuneResponses, highlighting their roles in #InflammatoryDiseases and future directions for understanding immune regulation under pathological conditions.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 29, 2026 at 11:55 AM
This review explores proton‑activated #GPCRs, pH‑sensing receptors that modulate #ImmuneResponses, highlighting their roles in #InflammatoryDiseases and future directions for understanding immune regulation under pathological conditions.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This review summarizes the #Biogenesis, components, and uptake of adipose tissue-derived #Exosomes, describing their role in #MetabolicDisorders and clinical applications while discussing current limitations and future therapeutic perspectives. #Medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 28, 2026 at 2:15 PM
This review summarizes the #Biogenesis, components, and uptake of adipose tissue-derived #Exosomes, describing their role in #MetabolicDisorders and clinical applications while discussing current limitations and future therapeutic perspectives. #Medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
#CymbopogonCitratus #EssentialOil inhibits #Isoproterenol-induced #cardiomyocyte hypertrophy by suppressing #NLRP3Inflammasome signaling and modulating oxidative phosphorylation complex subunits, highlighting its cardioprotective potential. #CVD
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 28, 2026 at 2:05 AM
#CymbopogonCitratus #EssentialOil inhibits #Isoproterenol-induced #cardiomyocyte hypertrophy by suppressing #NLRP3Inflammasome signaling and modulating oxidative phosphorylation complex subunits, highlighting its cardioprotective potential. #CVD
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
In this study, researchers found that #Hypokalemia occurred in 43.75% of gynecological patients recovering from #Anesthesia due to preoperative mechanical bowel preparation, though it had no significant effect on clinical outcomes. #medsky
To read more: doi.org/10.1007/s115...
To read more: doi.org/10.1007/s115...
January 27, 2026 at 1:15 PM
In this study, researchers found that #Hypokalemia occurred in 43.75% of gynecological patients recovering from #Anesthesia due to preoperative mechanical bowel preparation, though it had no significant effect on clinical outcomes. #medsky
To read more: doi.org/10.1007/s115...
To read more: doi.org/10.1007/s115...
Scientists show that #hemophilia carriers in #China frequently harbor identifiable F8/F9 mutations, exhibit variable #ClottingFactor levels with #BleedingRisk in low-level carriers, and display substantial psychological symptom burden.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 26, 2026 at 10:55 AM
Scientists show that #hemophilia carriers in #China frequently harbor identifiable F8/F9 mutations, exhibit variable #ClottingFactor levels with #BleedingRisk in low-level carriers, and display substantial psychological symptom burden.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This study identified that most GPI variants cluster in #Exons 3, 4, 12, and 18, and report novel pathogenic compound heterozygous variants that disrupt hydrogen bonds in highly conserved regions, potentially affecting GPI’s tertiary structure. #Medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 25, 2026 at 1:35 PM
This study identified that most GPI variants cluster in #Exons 3, 4, 12, and 18, and report novel pathogenic compound heterozygous variants that disrupt hydrogen bonds in highly conserved regions, potentially affecting GPI’s tertiary structure. #Medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Researchers report two novel #BEST1 mutations identified by #PacBio #SMRTSequencing in autosomal recessive #Bestrophinopathy, broadening the BEST1 mutation spectrum and highlighting the need for functional studies to advance #GeneTargetedTherapies.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 24, 2026 at 9:30 AM
Researchers report two novel #BEST1 mutations identified by #PacBio #SMRTSequencing in autosomal recessive #Bestrophinopathy, broadening the BEST1 mutation spectrum and highlighting the need for functional studies to advance #GeneTargetedTherapies.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
ZNF554 functions as a #TumorSuppressor in UCEC, inhibiting its progression by regulating the RBM5/WNT/beta-catenin signaling pathway, thus highlighting it as both a prognostic #Biomarker and a #TherapeuticTarget for UCEC.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 23, 2026 at 12:35 PM
ZNF554 functions as a #TumorSuppressor in UCEC, inhibiting its progression by regulating the RBM5/WNT/beta-catenin signaling pathway, thus highlighting it as both a prognostic #Biomarker and a #TherapeuticTarget for UCEC.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Scientists show that #ICEUS improves #ResidualTumor detection during malignant #glioma surgery and is linked to better overall and #ProgressionFreeSurvival, highlighting ICEUS as a #prognosticfactor and tool to enhance surgical outcomes.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 23, 2026 at 2:45 AM
Scientists show that #ICEUS improves #ResidualTumor detection during malignant #glioma surgery and is linked to better overall and #ProgressionFreeSurvival, highlighting ICEUS as a #prognosticfactor and tool to enhance surgical outcomes.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Using #FluidDynamics to study sidewall & bifurcation #Aneurysms, this study identified Size Ratio (SR) as a key morphological tool for distinguishing rupture risks and guiding #IntracranialAneurysm therapy. #Medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
January 22, 2026 at 12:01 PM
Using #FluidDynamics to study sidewall & bifurcation #Aneurysms, this study identified Size Ratio (SR) as a key morphological tool for distinguishing rupture risks and guiding #IntracranialAneurysm therapy. #Medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This work finds the airbag-selective #PortalVein blood arrester as a novel strategy to reduce #Hepatic #Ischemia/reperfusion injury during #Hepatectomy, highlighting it as a safe & effective approach with fewer #IatrogenicInjuries. #medsky
See: link.springer.com/article/10.1...
See: link.springer.com/article/10.1...
January 21, 2026 at 12:55 PM
This work finds the airbag-selective #PortalVein blood arrester as a novel strategy to reduce #Hepatic #Ischemia/reperfusion injury during #Hepatectomy, highlighting it as a safe & effective approach with fewer #IatrogenicInjuries. #medsky
See: link.springer.com/article/10.1...
See: link.springer.com/article/10.1...
This study shows that MMP13 promotes the formation of #DeepVeinThrombosis (DVT) while suppressing #Podoplanin expression, thereby advancing our understanding of #Thrombosis biology & offering new insights for DVT intervention. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
January 21, 2026 at 3:00 AM
This study shows that MMP13 promotes the formation of #DeepVeinThrombosis (DVT) while suppressing #Podoplanin expression, thereby advancing our understanding of #Thrombosis biology & offering new insights for DVT intervention. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
This study finds that #Scutellarein, a flavonoid isolated from Scutellaria barbata D. Don, demonstrates anti-#Osteoarthritis (OA) effects in rat models, highlighting its potential as a promising candidate for novel drug therapy in OA. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
January 20, 2026 at 1:45 PM
This study finds that #Scutellarein, a flavonoid isolated from Scutellaria barbata D. Don, demonstrates anti-#Osteoarthritis (OA) effects in rat models, highlighting its potential as a promising candidate for novel drug therapy in OA. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
#TRPM5 expression decreases in #Lipotoxic #βcelldysfunction while overexpression reverses GSIS impairment & restores #TranscriptionFactor activity, providing a theoretical foundation for novel #Type2Diabetes therapies. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
January 19, 2026 at 9:45 AM
#TRPM5 expression decreases in #Lipotoxic #βcelldysfunction while overexpression reverses GSIS impairment & restores #TranscriptionFactor activity, providing a theoretical foundation for novel #Type2Diabetes therapies. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
This study shows that #BoneMarrowMesenchymalStemCells-derived #Exosomes exert protective effects on #PeritonealDialysis-related #PeritonealFibrosis, mediated by #miR27a3p/#TP53 pathway & regulation of #Peritoneal miRNA #Homeostasis. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
January 18, 2026 at 11:55 AM
This study shows that #BoneMarrowMesenchymalStemCells-derived #Exosomes exert protective effects on #PeritonealDialysis-related #PeritonealFibrosis, mediated by #miR27a3p/#TP53 pathway & regulation of #Peritoneal miRNA #Homeostasis. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
This retrospective study investigates early #NeurologicalImpairment in adult patients with #Sepsis, identifying key influencing factors to inform prevention and treatment strategies aimed at improving #ClinicalOutcomes. #medsky
Full article: link.springer.com/article/10.1...
Full article: link.springer.com/article/10.1...
January 17, 2026 at 11:35 AM
This retrospective study investigates early #NeurologicalImpairment in adult patients with #Sepsis, identifying key influencing factors to inform prevention and treatment strategies aimed at improving #ClinicalOutcomes. #medsky
Full article: link.springer.com/article/10.1...
Full article: link.springer.com/article/10.1...
#GDF10 expression levels reflect #Tumorigenesis & prognosis in #LungSquamousCellCarcinoma & also function as indicators of #Immune infiltration & checkpoint expression, promising a potential diagnostic & #Therapeutic #Biomarker. #medsky
To read: link.springer.com/article/10.1...
To read: link.springer.com/article/10.1...
January 16, 2026 at 12:55 PM
#GDF10 expression levels reflect #Tumorigenesis & prognosis in #LungSquamousCellCarcinoma & also function as indicators of #Immune infiltration & checkpoint expression, promising a potential diagnostic & #Therapeutic #Biomarker. #medsky
To read: link.springer.com/article/10.1...
To read: link.springer.com/article/10.1...
This study highlights HZX-02-059, a dual-target inhibitor of #PIKfyve & #Tubulin, as lethal to #Bcell #AcuteLymphoblasticLeukaemia cells, underscoring its potential as a #therapeutic candidate for targeted #CancerTherapy. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
January 16, 2026 at 2:30 AM
This study highlights HZX-02-059, a dual-target inhibitor of #PIKfyve & #Tubulin, as lethal to #Bcell #AcuteLymphoblasticLeukaemia cells, underscoring its potential as a #therapeutic candidate for targeted #CancerTherapy. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
This study examines the effects of #Anesthesia techniques & #Pharmacological agents on #Postoperative #CognitiveDysfunction in elderly patients, providing a reference for rational anesthesia strategies to enhance #SurgicalOutcomes. #medsky
To read: link.springer.com/article/10.1...
To read: link.springer.com/article/10.1...
January 15, 2026 at 7:45 AM
This study examines the effects of #Anesthesia techniques & #Pharmacological agents on #Postoperative #CognitiveDysfunction in elderly patients, providing a reference for rational anesthesia strategies to enhance #SurgicalOutcomes. #medsky
To read: link.springer.com/article/10.1...
To read: link.springer.com/article/10.1...
This review examines the effects of polyamines & metabolic enzymes on #Neuronal functions and establishes a foundation for advancing our understanding of #Molecular regulation, offering new directions for #Neuroscience research. #medsky
To read: link.springer.com/article/10.1...
To read: link.springer.com/article/10.1...
January 14, 2026 at 12:20 PM
This review examines the effects of polyamines & metabolic enzymes on #Neuronal functions and establishes a foundation for advancing our understanding of #Molecular regulation, offering new directions for #Neuroscience research. #medsky
To read: link.springer.com/article/10.1...
To read: link.springer.com/article/10.1...
This study highlights the critical role of medical data and early warning technologies in the timely identification, monitoring, and prevention of #InfectiousDiseases. #Epidemiology #medsky
Read more: link.springer.com/article/10.1...
Read more: link.springer.com/article/10.1...
January 14, 2026 at 3:15 AM
This study highlights the critical role of medical data and early warning technologies in the timely identification, monitoring, and prevention of #InfectiousDiseases. #Epidemiology #medsky
Read more: link.springer.com/article/10.1...
Read more: link.springer.com/article/10.1...