Current Medical Science
@currentmedscience.bsky.social
Current Medical Science is a peer-reviewed journal publishing original, innovative & influential insightful reviews, comments, & special topic articles across diverse medical disciplines, including biomedicine, public health, and related fields.
Comprehensive profiling of #Exosome-derived serum metabolites in #SystemicLupusErythematosus patients identified key metabolites, their diagnostic & discriminative performance, and their association with disease progression.
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
December 18, 2025 at 11:45 AM
Comprehensive profiling of #Exosome-derived serum metabolites in #SystemicLupusErythematosus patients identified key metabolites, their diagnostic & discriminative performance, and their association with disease progression.
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
Development of a #DeepNeuralNetwork that significantly outperformed multiple #MachineLearning and #DeepLearning models in diagnosing #ParkinsonsDisease from handwritten spiral and wave images, achieving higher accuracy, sensitivity, and specificity.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 18, 2025 at 6:19 AM
Development of a #DeepNeuralNetwork that significantly outperformed multiple #MachineLearning and #DeepLearning models in diagnosing #ParkinsonsDisease from handwritten spiral and wave images, achieving higher accuracy, sensitivity, and specificity.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Demonstrating the first multimodal #3DImaging atlas of a rat BCI, fusing micro-CT & MRI data of the brain, arteries, & device with #MixedReality for interactive visualization, offering an objective reference for studying BCI. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 17, 2025 at 1:45 AM
Demonstrating the first multimodal #3DImaging atlas of a rat BCI, fusing micro-CT & MRI data of the brain, arteries, & device with #MixedReality for interactive visualization, offering an objective reference for studying BCI. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Non‑severe #AcquiredAplasticAnemia patients show persistently reduced circulating #Tregs even after #ImmunosuppressiveTherapy, highlighting that combining relative and absolute Treg counts may improve distinction of #BoneMarrow failure syndromes.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 16, 2025 at 9:30 AM
Non‑severe #AcquiredAplasticAnemia patients show persistently reduced circulating #Tregs even after #ImmunosuppressiveTherapy, highlighting that combining relative and absolute Treg counts may improve distinction of #BoneMarrow failure syndromes.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Using CT-DCG, this study provides essential anatomical insights into the spatial relationship between the LS & middle turbinate axilla in Chinese patients with nasolacrimal duct obstruction, showing that it varies by gender & disease type. #ENT #MedicalResearch
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 15, 2025 at 12:01 PM
Using CT-DCG, this study provides essential anatomical insights into the spatial relationship between the LS & middle turbinate axilla in Chinese patients with nasolacrimal duct obstruction, showing that it varies by gender & disease type. #ENT #MedicalResearch
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Scientists demonstrate that #electroacupuncture at ST36 and LR3 enhances #gastrointestinalmotility in #FunctionalDyspepsia rats by activating the GDNF/GFRα1/PI3K/Akt pathway and thereby improving #gastrointestinal function and alleviating FD symptoms.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 14, 2025 at 2:13 AM
Scientists demonstrate that #electroacupuncture at ST36 and LR3 enhances #gastrointestinalmotility in #FunctionalDyspepsia rats by activating the GDNF/GFRα1/PI3K/Akt pathway and thereby improving #gastrointestinal function and alleviating FD symptoms.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This study shows that yinchenhao decoction + praziquantel mitigates schistosomiasis-associated hepatic granulomatous #Iinflammation and #Fibrosis by inhibiting hepatic #Apoptosis & #ERstress in a #Schistosomiasis mouse model. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 13, 2025 at 10:15 AM
This study shows that yinchenhao decoction + praziquantel mitigates schistosomiasis-associated hepatic granulomatous #Iinflammation and #Fibrosis by inhibiting hepatic #Apoptosis & #ERstress in a #Schistosomiasis mouse model. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Researchers demonstrate that NEP1-40 promotes hippocampal #NeuralStemCell differentiation into #neurons and reduces #astrocyte proliferation and #neuronalapoptosis, leading to improved #cognitive and behavioral symptoms in #schizophrenia mouse models.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 12, 2025 at 1:45 PM
Researchers demonstrate that NEP1-40 promotes hippocampal #NeuralStemCell differentiation into #neurons and reduces #astrocyte proliferation and #neuronalapoptosis, leading to improved #cognitive and behavioral symptoms in #schizophrenia mouse models.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
On this #UniversalHealthCoverageDay, @cmedicalscience reaffirms its commitment to a future where everyone has access to quality #healthcare—when they need it, where they need it, and without financial burden.
Healthcare is a #FundamentalHumanRight
Healthcare is a #FundamentalHumanRight
December 12, 2025 at 9:01 AM
On this #UniversalHealthCoverageDay, @cmedicalscience reaffirms its commitment to a future where everyone has access to quality #healthcare—when they need it, where they need it, and without financial burden.
Healthcare is a #FundamentalHumanRight
Healthcare is a #FundamentalHumanRight
Chop deficiency exacerbates #Inflammation, tissue injury, macrophage infiltration and bladder epithelial apoptosis in #cyclophosphamide-induced overactive bladder (OAB) by inhibiting #ERstress.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 12, 2025 at 2:00 AM
Chop deficiency exacerbates #Inflammation, tissue injury, macrophage infiltration and bladder epithelial apoptosis in #cyclophosphamide-induced overactive bladder (OAB) by inhibiting #ERstress.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Physiological reconstruction for severe #PelvicOrganProlapse—restoring #PelvicFloor support and #vaginal axis via mesh repair and #MuscleReconstruction—delivers significant objective and subjective improvements with minimal complication rates.
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
December 11, 2025 at 12:30 PM
Physiological reconstruction for severe #PelvicOrganProlapse—restoring #PelvicFloor support and #vaginal axis via mesh repair and #MuscleReconstruction—delivers significant objective and subjective improvements with minimal complication rates.
#OpenAccess: doi.org/10.1007/s115...
#OpenAccess: doi.org/10.1007/s115...
Long maternal sleep duration may exert a direct & prolonged negative impact on head circumference & fetal biparietal diameter, underscoring the importance of proper sleep duration during pregnancy. #medsky
#MaternalHealth #Pregnancy
Current Medical Science: doi.org/10.1007/s115...
#MaternalHealth #Pregnancy
Current Medical Science: doi.org/10.1007/s115...
December 10, 2025 at 12:02 PM
Long maternal sleep duration may exert a direct & prolonged negative impact on head circumference & fetal biparietal diameter, underscoring the importance of proper sleep duration during pregnancy. #medsky
#MaternalHealth #Pregnancy
Current Medical Science: doi.org/10.1007/s115...
#MaternalHealth #Pregnancy
Current Medical Science: doi.org/10.1007/s115...
A novel 26-plex #ShortTandemRepeat #GenotypingAssay enables accurate identification of CHM without #maternal tissue by integrating multi-chromosomal STRs with p57 #immunohistochemistry, enhancing diagnostic reliability and supporting #GeneticCounseling.#Genetics
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 10, 2025 at 2:15 AM
A novel 26-plex #ShortTandemRepeat #GenotypingAssay enables accurate identification of CHM without #maternal tissue by integrating multi-chromosomal STRs with p57 #immunohistochemistry, enhancing diagnostic reliability and supporting #GeneticCounseling.#Genetics
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Using #Multiomics data integration, this Current Medical Science study from @WHU_1893 identified seven #HubGenes that mechanistically connect #ImmuneDyshomeostasis to #TissueInjury in #Sepsis-induced ALI. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 9, 2025 at 9:30 AM
Using #Multiomics data integration, this Current Medical Science study from @WHU_1893 identified seven #HubGenes that mechanistically connect #ImmuneDyshomeostasis to #TissueInjury in #Sepsis-induced ALI. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
Researchers developed a #nomogram-based model using #lactate, coagulation index, #creatinine, and the #SepsisInducedCoagulopathy (SIC) score to predict SIC, showing strong calibration and clinical utility. #Sepsis
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
December 8, 2025 at 1:15 PM
Researchers developed a #nomogram-based model using #lactate, coagulation index, #creatinine, and the #SepsisInducedCoagulopathy (SIC) score to predict SIC, showing strong calibration and clinical utility. #Sepsis
Read more: doi.org/10.1007/s115...
Read more: doi.org/10.1007/s115...
This Current Medical Science study shows that maternal electronic cigarette exposure induces #OxidativeStress & DNA hypomethylation, leading to #Autophagy dysregulation and exacerbated PH in offspring. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 7, 2025 at 2:00 AM
This Current Medical Science study shows that maternal electronic cigarette exposure induces #OxidativeStress & DNA hypomethylation, leading to #Autophagy dysregulation and exacerbated PH in offspring. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This review highlights how #TranscriptionFactors drive lipid dysregulation, #Inflammation, #OxidativeStress, #Fibrosis, & metabolic imbalance in #AlcoholicLiverDisease, and outlines emerging TF-targeted therapeutic strategies to improve ALD management.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 6, 2025 at 6:30 AM
This review highlights how #TranscriptionFactors drive lipid dysregulation, #Inflammation, #OxidativeStress, #Fibrosis, & metabolic imbalance in #AlcoholicLiverDisease, and outlines emerging TF-targeted therapeutic strategies to improve ALD management.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This Current Medical Science shows that #Dapagliflozin improves heart function, alleviates #MyocardiaInjury and mitigates #MyocardialFibrosis by suppressing HIF-1α/TGF-β-mediated #Cuproptosis. #medsky
To read more, click here: doi.org/10.1007/s115...
To read more, click here: doi.org/10.1007/s115...
December 5, 2025 at 12:45 PM
This Current Medical Science shows that #Dapagliflozin improves heart function, alleviates #MyocardiaInjury and mitigates #MyocardialFibrosis by suppressing HIF-1α/TGF-β-mediated #Cuproptosis. #medsky
To read more, click here: doi.org/10.1007/s115...
To read more, click here: doi.org/10.1007/s115...
A pathogenic S100A9–TLR2 feedback loop amplifies #hypertrophic and #InflammatorySignaling in mechanically stressed #cardiomyocytes, linking immune dysregulation to maladaptive #CardiacRemodeling and highlighting a therapeutic target in #HeartFailure.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
December 5, 2025 at 5:45 AM
A pathogenic S100A9–TLR2 feedback loop amplifies #hypertrophic and #InflammatorySignaling in mechanically stressed #cardiomyocytes, linking immune dysregulation to maladaptive #CardiacRemodeling and highlighting a therapeutic target in #HeartFailure.
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
This study explored the immune cell-related #Ferroptosis genes (ICRFGs) in #DiabeticKidneyDisease and identified ALOX5 as the most crucial ICRFG, which may serve as a reliable and prospective #Diagnostic #Biomarker. #medsky
Read here: doi.org/10.1007/s115...
Read here: doi.org/10.1007/s115...
December 4, 2025 at 9:00 AM
This study explored the immune cell-related #Ferroptosis genes (ICRFGs) in #DiabeticKidneyDisease and identified ALOX5 as the most crucial ICRFG, which may serve as a reliable and prospective #Diagnostic #Biomarker. #medsky
Read here: doi.org/10.1007/s115...
Read here: doi.org/10.1007/s115...
This study reveals that patients with early-onset diabetes and multigenerational family history harbor #GeneVariants, underscoring #GeneticScreening as the key to precise diagnosis, tailored therapy, prognosis evaluation, and counseling. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
December 3, 2025 at 1:15 PM
This study reveals that patients with early-onset diabetes and multigenerational family history harbor #GeneVariants, underscoring #GeneticScreening as the key to precise diagnosis, tailored therapy, prognosis evaluation, and counseling. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
This study revealed consistently elevated ZWINT #mRNA and #ProteinExpression in #BreastCancer, with high ZWINT levels linked to #CDH1 and #TP53 #Mutations and correlated with poorer #SurvivalOutcomes. #medsky
To read: link.springer.com/article/10.1...
To read: link.springer.com/article/10.1...
December 3, 2025 at 8:30 AM
This study revealed consistently elevated ZWINT #mRNA and #ProteinExpression in #BreastCancer, with high ZWINT levels linked to #CDH1 and #TP53 #Mutations and correlated with poorer #SurvivalOutcomes. #medsky
To read: link.springer.com/article/10.1...
To read: link.springer.com/article/10.1...
This study identifies #Quercetin, #Kaempferol, & #Naringenin as promising compounds in SZKJT, a Chinese herbal formulation, targeting #COX2, #TNF, #BCL2, & #Caspase3 to suppress #TumorGrowth, #Inflammation, & #OxidativeStress in OSCC. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
December 2, 2025 at 6:00 AM
This study identifies #Quercetin, #Kaempferol, & #Naringenin as promising compounds in SZKJT, a Chinese herbal formulation, targeting #COX2, #TNF, #BCL2, & #Caspase3 to suppress #TumorGrowth, #Inflammation, & #OxidativeStress in OSCC. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
This review identifies the subnucleus reticularis dorsalis (SRD) as a promising target for innovative #Analgesic therapies, examining strategies that modulate SRD and revealing new directions for advancing #PainManagement. #medsky
Full article here: link.springer.com/article/10.1...
Full article here: link.springer.com/article/10.1...
December 1, 2025 at 12:45 PM
This review identifies the subnucleus reticularis dorsalis (SRD) as a promising target for innovative #Analgesic therapies, examining strategies that modulate SRD and revealing new directions for advancing #PainManagement. #medsky
Full article here: link.springer.com/article/10.1...
Full article here: link.springer.com/article/10.1...
This review examines the mechanisms of #miR-146a in #NeurodegenerativeDiseases and explores future prospects, adding to ongoing research on #MolecularTargets in #Neurodegeneration. #medsky
Read full article here: link.springer.com/article/10.1...
Read full article here: link.springer.com/article/10.1...
November 30, 2025 at 8:30 AM
This review examines the mechanisms of #miR-146a in #NeurodegenerativeDiseases and explores future prospects, adding to ongoing research on #MolecularTargets in #Neurodegeneration. #medsky
Read full article here: link.springer.com/article/10.1...
Read full article here: link.springer.com/article/10.1...