Dan Tyrrell
@danis1337.bsky.social
Asst. Professor at UAB Pathology | T cells, aging, mitos, 🧠,🫀, ☕️, 🐭, 🔬, data vis | He/him | Views mine
Reposted by Dan Tyrrell
#MicrovascularAging 🐴Tendon
Young 2~5 y/o
Aged 18~22 y/o
Superficial digital flexor tendon
⏬μCT microvascular (φ>=37 μm) density, φ
⏫VWF+ microvessels
⏫PDGFRβ+ pericytes
⏬Des+/Myh11+ mural cells
5 mm cubes for 3D immunostaining
#AgingCell 2025
onlinelibrary.wiley.com/doi/10.1111/...
Young 2~5 y/o
Aged 18~22 y/o
Superficial digital flexor tendon
⏬μCT microvascular (φ>=37 μm) density, φ
⏫VWF+ microvessels
⏫PDGFRβ+ pericytes
⏬Des+/Myh11+ mural cells
5 mm cubes for 3D immunostaining
#AgingCell 2025
onlinelibrary.wiley.com/doi/10.1111/...
November 26, 2025 at 12:34 PM
#MicrovascularAging 🐴Tendon
Young 2~5 y/o
Aged 18~22 y/o
Superficial digital flexor tendon
⏬μCT microvascular (φ>=37 μm) density, φ
⏫VWF+ microvessels
⏫PDGFRβ+ pericytes
⏬Des+/Myh11+ mural cells
5 mm cubes for 3D immunostaining
#AgingCell 2025
onlinelibrary.wiley.com/doi/10.1111/...
Young 2~5 y/o
Aged 18~22 y/o
Superficial digital flexor tendon
⏬μCT microvascular (φ>=37 μm) density, φ
⏫VWF+ microvessels
⏫PDGFRβ+ pericytes
⏬Des+/Myh11+ mural cells
5 mm cubes for 3D immunostaining
#AgingCell 2025
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Dan Tyrrell
“Time is brain” for cell therapies?🧠
Our #AdvSci perspective😆
@rrust.bsky.social
@dominikusbrian.com
@lydenlab.bsky.social
#StemCellTherapy for #Stroke should be timed to a biomarker-defined “window of receptivity”, not just the thrombolysis clock
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Our #AdvSci perspective😆
@rrust.bsky.social
@dominikusbrian.com
@lydenlab.bsky.social
#StemCellTherapy for #Stroke should be timed to a biomarker-defined “window of receptivity”, not just the thrombolysis clock
advanced.onlinelibrary.wiley.com/doi/10.1002/...
November 18, 2025 at 8:07 PM
“Time is brain” for cell therapies?🧠
Our #AdvSci perspective😆
@rrust.bsky.social
@dominikusbrian.com
@lydenlab.bsky.social
#StemCellTherapy for #Stroke should be timed to a biomarker-defined “window of receptivity”, not just the thrombolysis clock
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Our #AdvSci perspective😆
@rrust.bsky.social
@dominikusbrian.com
@lydenlab.bsky.social
#StemCellTherapy for #Stroke should be timed to a biomarker-defined “window of receptivity”, not just the thrombolysis clock
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Columbus was interesting. There was so much superstition and unknown in the 1400’s. The main motivation for finding new lands was basically to bring gold back to the Spanish King and Queen. By that metric, Columbus was a failure
November 16, 2025 at 3:29 PM
Columbus was interesting. There was so much superstition and unknown in the 1400’s. The main motivation for finding new lands was basically to bring gold back to the Spanish King and Queen. By that metric, Columbus was a failure
When did football announcers decide to start saying ‘2-minute timeout’ and ‘red area’ instead of 2-minute warning and red zone
November 15, 2025 at 6:27 PM
When did football announcers decide to start saying ‘2-minute timeout’ and ‘red area’ instead of 2-minute warning and red zone
Hannibal was very cool in an ancient type of way. The whole elephant over the alps thing is pretty overblown though. They all died almost right away
November 13, 2025 at 11:25 PM
Hannibal was very cool in an ancient type of way. The whole elephant over the alps thing is pretty overblown though. They all died almost right away
I need to settle a family debate. Is The Nightmare Before Christmas a Halloween movie or Christmas movie?
November 6, 2025 at 12:32 AM
I need to settle a family debate. Is The Nightmare Before Christmas a Halloween movie or Christmas movie?
Submitting a 2nd R01 application to a gov’t bureaucracy that isn’t there. Do we have to meet deadlines to fulfill our obligation? Yes. Does the gov’t? No, apparently
November 3, 2025 at 6:10 PM
Submitting a 2nd R01 application to a gov’t bureaucracy that isn’t there. Do we have to meet deadlines to fulfill our obligation? Yes. Does the gov’t? No, apparently
This was super interesting. That trip would have sucked but they survived mostly intact
November 3, 2025 at 4:21 PM
This was super interesting. That trip would have sucked but they survived mostly intact
This was a cool book. The underground resistance in the Netherlands during WWII. So cool how women were so overlooked in some cases that they could do really covert espionage for the allies
October 30, 2025 at 12:58 PM
This was a cool book. The underground resistance in the Netherlands during WWII. So cool how women were so overlooked in some cases that they could do really covert espionage for the allies
This was pretty good. Short and fairly Euro-centric but still good
October 25, 2025 at 1:39 PM
This was pretty good. Short and fairly Euro-centric but still good
Original investigative journalism. Get yourself committed to an asylum and report on the horrible conditions. Pretty interesting but weird to call the ‘inmates’ lunatics or insane over and over
October 25, 2025 at 1:37 PM
Original investigative journalism. Get yourself committed to an asylum and report on the horrible conditions. Pretty interesting but weird to call the ‘inmates’ lunatics or insane over and over
This was interesting. Had the expect racist words and remarks that I think were fairly common in the early 1900’s. Otherwise was an interesting struggle between Native peoples and European immigrants in the American west
October 21, 2025 at 11:07 AM
This was interesting. Had the expect racist words and remarks that I think were fairly common in the early 1900’s. Otherwise was an interesting struggle between Native peoples and European immigrants in the American west
Reposted by Dan Tyrrell
A phylogenetic tree of plasmodial slime molds & their common features
October 21, 2025 at 6:28 AM
A phylogenetic tree of plasmodial slime molds & their common features
This was super compelling. Definitely romanticized war in parts, and odd to hear German perspective in WWI. Didn’t know much about Ernst Jünger before. Interesting/controversial character
October 18, 2025 at 12:40 AM
This was super compelling. Definitely romanticized war in parts, and odd to hear German perspective in WWI. Didn’t know much about Ernst Jünger before. Interesting/controversial character
reviewing someone's biosketch who lists trainees like: name1 (male, American), name2 (female, African American), name3 (female, Indian)...
not sure why anyone would do this, but if you do, Don't. Weird. Icky. Uncool. Morally/Ethically wrong....😵💫
not sure why anyone would do this, but if you do, Don't. Weird. Icky. Uncool. Morally/Ethically wrong....😵💫
October 17, 2025 at 2:54 PM
reviewing someone's biosketch who lists trainees like: name1 (male, American), name2 (female, African American), name3 (female, Indian)...
not sure why anyone would do this, but if you do, Don't. Weird. Icky. Uncool. Morally/Ethically wrong....😵💫
not sure why anyone would do this, but if you do, Don't. Weird. Icky. Uncool. Morally/Ethically wrong....😵💫
1177 was tough to get through. Lots of facts but narrative was not my style. Guns, Germs, and Steel was good. I had to read Collapse in college and this was similar and also good.
October 15, 2025 at 10:59 AM
1177 was tough to get through. Lots of facts but narrative was not my style. Guns, Germs, and Steel was good. I had to read Collapse in college and this was similar and also good.
Reposted by Dan Tyrrell
PLEASE SPREAD THE WORD!!
The University of Texas-Austin is beginning a process to eliminate the Black Studies, Latino Studies, and Gender Studies departments in the College of Liberal Arts. This is a grave threat to the educational liberty of students, faculty, staff, and the people of Texas. 1/
The University of Texas-Austin is beginning a process to eliminate the Black Studies, Latino Studies, and Gender Studies departments in the College of Liberal Arts. This is a grave threat to the educational liberty of students, faculty, staff, and the people of Texas. 1/
October 13, 2025 at 4:37 PM
PLEASE SPREAD THE WORD!!
The University of Texas-Austin is beginning a process to eliminate the Black Studies, Latino Studies, and Gender Studies departments in the College of Liberal Arts. This is a grave threat to the educational liberty of students, faculty, staff, and the people of Texas. 1/
The University of Texas-Austin is beginning a process to eliminate the Black Studies, Latino Studies, and Gender Studies departments in the College of Liberal Arts. This is a grave threat to the educational liberty of students, faculty, staff, and the people of Texas. 1/
still waiting for Billy Joel's we_didnt_start_the_fire_v2.mp3
October 6, 2025 at 6:04 PM
still waiting for Billy Joel's we_didnt_start_the_fire_v2.mp3
Reposted by Dan Tyrrell
Reposted by Dan Tyrrell
10/10 💀
Children are wonderful. However, there are situations in which parents must minimize time spent on an activity while maximizing a child’s enjoyment of it.
Here, we analyze the problem of a bedtime routine that involves playing CandyLand w a toddler who does not take kindly to losing... 👇
Children are wonderful. However, there are situations in which parents must minimize time spent on an activity while maximizing a child’s enjoyment of it.
Here, we analyze the problem of a bedtime routine that involves playing CandyLand w a toddler who does not take kindly to losing... 👇
October 6, 2025 at 4:57 PM
10/10 💀
Children are wonderful. However, there are situations in which parents must minimize time spent on an activity while maximizing a child’s enjoyment of it.
Here, we analyze the problem of a bedtime routine that involves playing CandyLand w a toddler who does not take kindly to losing... 👇
Children are wonderful. However, there are situations in which parents must minimize time spent on an activity while maximizing a child’s enjoyment of it.
Here, we analyze the problem of a bedtime routine that involves playing CandyLand w a toddler who does not take kindly to losing... 👇
This one was alright. Way too western and male focused. Don’t think South America was mentioned at all. Still interesting
October 6, 2025 at 12:54 AM
This one was alright. Way too western and male focused. Don’t think South America was mentioned at all. Still interesting
Do people at UCLA not enjoy football? They’re trying to upset Penn state and nobody is there
October 4, 2025 at 9:24 PM
Do people at UCLA not enjoy football? They’re trying to upset Penn state and nobody is there
Haven’t shared my latest books. All on a theme of WWII and the rise of fascism (wonder why). All good. Code breaking sisters WWII autobiography was my fav. Chinas good war was super interesting too
October 3, 2025 at 12:51 AM
Haven’t shared my latest books. All on a theme of WWII and the rise of fascism (wonder why). All good. Code breaking sisters WWII autobiography was my fav. Chinas good war was super interesting too