Dave Carlson
@davecarlson.bsky.social
PhD in EcoEvo. Bioinformatics & High Performance Computing. Transposon enthusiast.
Reposted by Dave Carlson
We are excited to share our recent work on the surprising robustness of Ancestral Recombination Graph (ARG) inference tools to computational phasing errors, now available on BioRxiv: biorxiv.org/content/10.1....
This work is co-advised by @yundeng.bsky.social and Rasmus Nielsen.
1/7
This work is co-advised by @yundeng.bsky.social and Rasmus Nielsen.
1/7
Robustness of Ancestral Recombination Graph Inference Tools to Phasing Errors
Ancestral Recombination Graphs (ARGs) are fundamental population genetic structures that encode the genealogical history of a sample of haplotypes along the genome. They have recently received substan...
biorxiv.org
November 26, 2025 at 5:09 PM
We are excited to share our recent work on the surprising robustness of Ancestral Recombination Graph (ARG) inference tools to computational phasing errors, now available on BioRxiv: biorxiv.org/content/10.1....
This work is co-advised by @yundeng.bsky.social and Rasmus Nielsen.
1/7
This work is co-advised by @yundeng.bsky.social and Rasmus Nielsen.
1/7
Reposted by Dave Carlson
November 24, 2025 at 11:46 PM
Reposted by Dave Carlson
you'd think the forced displacement of 10 million people from one of the oldest centres of civilisation in human history would get a little more news attention than beltway journalists writing essays on how Olivia Nuzzi is a genius because they want to bone her and you'd be wrong
'Iran’s capital must be moved because the country “no longer has a choice,” President Masoud Pezeshkian said on Thursday in remarks carried by state media, warning that severe ecological strain has made Tehran impossible to sustain'
#Iran 🇮🇷
#Iran 🇮🇷
Iran president says capital move now a necessity as water crisis deepens
Iran’s capital must be moved because the country “no longer has a choice,” President Masoud Pezeshkian said on Thursday in remarks carried by state media, warning that severe ecological strain has mad...
www.iranintl.com
November 21, 2025 at 7:59 PM
you'd think the forced displacement of 10 million people from one of the oldest centres of civilisation in human history would get a little more news attention than beltway journalists writing essays on how Olivia Nuzzi is a genius because they want to bone her and you'd be wrong
Reposted by Dave Carlson
PHOTOS: TPM Celebrates Our 25-Year Anniversary in NYC talkingpointsmemo.com/gallery/phot...
PHOTOS: TPM Celebrates Our 25-Year Anniversary in NYC
We rang in our 25th anniversary in style last week, hosting a...
talkingpointsmemo.com
November 19, 2025 at 6:42 PM
PHOTOS: TPM Celebrates Our 25-Year Anniversary in NYC talkingpointsmemo.com/gallery/phot...
I can't help but feel that if we could go back to 1997 and somehow prevent Limp Bizkit from becoming popular, the present timeline would be a lot better.
November 16, 2025 at 7:02 PM
I can't help but feel that if we could go back to 1997 and somehow prevent Limp Bizkit from becoming popular, the present timeline would be a lot better.
Reposted by Dave Carlson
NEW pub in @science.org 🥳
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
November 13, 2025 at 8:34 PM
NEW pub in @science.org 🥳
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Reposted by Dave Carlson
With Watson's death can we stop teaching his simplified version of the Central Dogma (DNA-RNA-protein) & instead teach what Crick actually proposed? It promotes understanding & critical thinking. wellcomecollection.org/works/xmscu3...
November 13, 2025 at 11:13 PM
With Watson's death can we stop teaching his simplified version of the Central Dogma (DNA-RNA-protein) & instead teach what Crick actually proposed? It promotes understanding & critical thinking. wellcomecollection.org/works/xmscu3...
Was the serial killer in Thomas Harris's Red Dragon inspired by Epstein?!?
November 13, 2025 at 12:34 PM
Was the serial killer in Thomas Harris's Red Dragon inspired by Epstein?!?
Reposted by Dave Carlson
You see Trump working the phones and realize White Housers are looking at this morning's emails and thinking, who cares abuot those nothingburgers we need to flip boebert so the bad stuff doesn't come out.
November 12, 2025 at 6:42 PM
You see Trump working the phones and realize White Housers are looking at this morning's emails and thinking, who cares abuot those nothingburgers we need to flip boebert so the bad stuff doesn't come out.
Reposted by Dave Carlson
This is one of the most remarkable academic debacles I've ever seen.
A large RCT got published in BMJ. There are currently 44 Pubpeer comments, mostly about the data, including...well. Read for yourself.
pubpeer.com/publications...
A large RCT got published in BMJ. There are currently 44 Pubpeer comments, mostly about the data, including...well. Read for yourself.
pubpeer.com/publications...
PubPeer - Prevention of acute myocardial infarction induced heart fail...
There are comments on PubPeer for publication: Prevention of acute myocardial infarction induced heart failure by intracoronary infusion of mesenchymal stem cells: phase 3 randomised clinical trial (P...
pubpeer.com
November 11, 2025 at 1:19 AM
This is one of the most remarkable academic debacles I've ever seen.
A large RCT got published in BMJ. There are currently 44 Pubpeer comments, mostly about the data, including...well. Read for yourself.
pubpeer.com/publications...
A large RCT got published in BMJ. There are currently 44 Pubpeer comments, mostly about the data, including...well. Read for yourself.
pubpeer.com/publications...
November 10, 2025 at 2:33 AM
Reposted by Dave Carlson
Prescient
Chris Murphy: "There will be pretty substantial damage to a Dem brand that has been rehabilitated if on the heels of an election in which the people told us to keep fighting, we immediately stop... if we surrender without having gotten anything, I worry it'll be hard to get them back up off the mat"
November 10, 2025 at 2:19 AM
Prescient
We'll have to see how the votes shake out, but these are the D senators up for reelection next year
Source: www.senate.gov/senators/Cla...
Source: www.senate.gov/senators/Cla...
November 10, 2025 at 12:41 AM
We'll have to see how the votes shake out, but these are the D senators up for reelection next year
Source: www.senate.gov/senators/Cla...
Source: www.senate.gov/senators/Cla...
Reposted by Dave Carlson
If Dems cave on health care subsidies, I might actually lose my fucking mind.
"A vote in Senate on the issue" is 1000% meaningless.
"A vote in Senate on the issue" is 1000% meaningless.
From what I have seen so far this does not seem like a good deal:
November 9, 2025 at 8:11 PM
If Dems cave on health care subsidies, I might actually lose my fucking mind.
"A vote in Senate on the issue" is 1000% meaningless.
"A vote in Senate on the issue" is 1000% meaningless.
My wife and I disagree frequently about what version of "Landslide" is better. She prefers the original, while I think that the Chicks cover is better.
I need you all to settle the debate - what version of Landslide is the best? Fleetwood, Chicks, Pumpkins, some other?
I need you all to settle the debate - what version of Landslide is the best? Fleetwood, Chicks, Pumpkins, some other?
November 8, 2025 at 6:42 PM
My wife and I disagree frequently about what version of "Landslide" is better. She prefers the original, while I think that the Chicks cover is better.
I need you all to settle the debate - what version of Landslide is the best? Fleetwood, Chicks, Pumpkins, some other?
I need you all to settle the debate - what version of Landslide is the best? Fleetwood, Chicks, Pumpkins, some other?
Reposted by Dave Carlson
JOIN US LIVE FOR THE WORLD CUP 2026 DRAW 🏆
Dec. 5 we'll be LIVE at Manhattan Center's Grand Ballroom with our great friends at Verizon to watch, react to, & dissect the World Cup Draw with special guests, bold predictions, & unbridled joy.
🎟️ Tickets: mibcourage.co/4oXgXdm
Dec. 5 we'll be LIVE at Manhattan Center's Grand Ballroom with our great friends at Verizon to watch, react to, & dissect the World Cup Draw with special guests, bold predictions, & unbridled joy.
🎟️ Tickets: mibcourage.co/4oXgXdm
November 7, 2025 at 3:17 PM
JOIN US LIVE FOR THE WORLD CUP 2026 DRAW 🏆
Dec. 5 we'll be LIVE at Manhattan Center's Grand Ballroom with our great friends at Verizon to watch, react to, & dissect the World Cup Draw with special guests, bold predictions, & unbridled joy.
🎟️ Tickets: mibcourage.co/4oXgXdm
Dec. 5 we'll be LIVE at Manhattan Center's Grand Ballroom with our great friends at Verizon to watch, react to, & dissect the World Cup Draw with special guests, bold predictions, & unbridled joy.
🎟️ Tickets: mibcourage.co/4oXgXdm
I am once again begging research software engineers to google their application's acronym before publication.
November 7, 2025 at 1:47 PM
I am once again begging research software engineers to google their application's acronym before publication.
4 billion years of evolution >>> 4, 40, or 400 billion dollars
My favorite comment on the FT story
November 6, 2025 at 10:00 PM
4 billion years of evolution >>> 4, 40, or 400 billion dollars
Reposted by Dave Carlson
The detectCores() apocalypse is creeping up on us 👻🐛
As more people are getting access to 128+ CPU cores, code spinning up parallel cluster with detectCores() workers fails - not enough #RStats connections available
Friends, do *not* default to detectCores(), bc www.jottr.org/2022/12/05/a...
As more people are getting access to 128+ CPU cores, code spinning up parallel cluster with detectCores() workers fails - not enough #RStats connections available
Friends, do *not* default to detectCores(), bc www.jottr.org/2022/12/05/a...
Please Avoid detectCores() in your R Packages
The detectCores() function of the parallel package is probably one of the most used functions when it comes to setting the number of parallel workers to use in R. In this blog post, I’ll try to explai...
www.jottr.org
November 5, 2025 at 11:55 PM
The detectCores() apocalypse is creeping up on us 👻🐛
As more people are getting access to 128+ CPU cores, code spinning up parallel cluster with detectCores() workers fails - not enough #RStats connections available
Friends, do *not* default to detectCores(), bc www.jottr.org/2022/12/05/a...
As more people are getting access to 128+ CPU cores, code spinning up parallel cluster with detectCores() workers fails - not enough #RStats connections available
Friends, do *not* default to detectCores(), bc www.jottr.org/2022/12/05/a...
Reposted by Dave Carlson
The shift in Connecticut tonight is seismic. Possibly unprecedented. Loads of towns flipped from Republican to Democratic control.
A partial list:
Ansonia
Bethany
Branford
Bristol
Brooklyn
East Granby
Ellington
Enfield
Farmington
Milford
New Britain
New Fairfield
Norwich
Plymouth
Rocky Hill
A partial list:
Ansonia
Bethany
Branford
Bristol
Brooklyn
East Granby
Ellington
Enfield
Farmington
Milford
New Britain
New Fairfield
Norwich
Plymouth
Rocky Hill
November 5, 2025 at 9:51 AM
The shift in Connecticut tonight is seismic. Possibly unprecedented. Loads of towns flipped from Republican to Democratic control.
A partial list:
Ansonia
Bethany
Branford
Bristol
Brooklyn
East Granby
Ellington
Enfield
Farmington
Milford
New Britain
New Fairfield
Norwich
Plymouth
Rocky Hill
A partial list:
Ansonia
Bethany
Branford
Bristol
Brooklyn
East Granby
Ellington
Enfield
Farmington
Milford
New Britain
New Fairfield
Norwich
Plymouth
Rocky Hill
I really hate that we can't make "hang that in the Louvre" jokes anymore.
November 4, 2025 at 4:57 PM
I really hate that we can't make "hang that in the Louvre" jokes anymore.
Reposted by Dave Carlson
The New York Post made this image about rich people fleeing Mamdani and, as someone familiar with both cities, I will say: haha ok
November 3, 2025 at 11:53 AM
The New York Post made this image about rich people fleeing Mamdani and, as someone familiar with both cities, I will say: haha ok
Reposted by Dave Carlson
NYC is going to have the world's biggest media-manufactured crime panic in history the second Mamdani is elected. They aren't even going to wait until he is inaugurated. Whether or not you like the guy, you need to start preparing now for the fire hose of disinformation that is about to activate.
November 2, 2025 at 11:19 PM
NYC is going to have the world's biggest media-manufactured crime panic in history the second Mamdani is elected. They aren't even going to wait until he is inaugurated. Whether or not you like the guy, you need to start preparing now for the fire hose of disinformation that is about to activate.
Reposted by Dave Carlson
Stony Brook is hiring an Assistant or Associate Professor in Marine Molecular Ecology (assistant encouraged, molecular broadly defined, includes microbial omics!): apply.interfolio.com/174869
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 7, 2025 at 6:38 PM
Stony Brook is hiring an Assistant or Associate Professor in Marine Molecular Ecology (assistant encouraged, molecular broadly defined, includes microbial omics!): apply.interfolio.com/174869