2025 NFL Regular Season Week 5 TV and Announcer Schedule
The Philadelphia Eagles (4-0) try to retain the distinction of being the last unbeaten team in the NFC when they host the Denver Broncos (2-2) (CBS/Paramount+, Oct. 5 @ 1:00 PM ET). Bo Nix threw for 326 yards and accounted for three touchdowns as Denver crushed Cincinnati 28-3 to close out Week 4.
Chargers have won five of the past six meetings with Washington (Fox, Oct. 5 @ 4:25 PM ET), including a 20-16 victory on Sept. 12, 2021, as Justin Herbert threw for 337 yards and a TD.
The following is this week’s NFL regular season schedule, including dates, start times, TV networks and scheduled announcers.
Thursday, October 2, 2025
San Francisco 49ers at Los Angeles Rams [Prime Video, 8:15p (ET)/5:15p (PT)]
Also airing on KTVU (FOX/2) in San Francisco and KTTV (FOX/11) in Los Angeles
Announcers: Al Michaels, Kirk Herbstreit, Kaylee Hartung
Longtime rivals in the 49ers and Rams vie for early-season supremacy in the NFC West. The 3-1 clubs are joined by Seattle atop the division. San Francisco quarterback Brock Purdy aggravated his toe injury in a 26-21 loss to Jacksonville in Week 4.
Sunday, October 5, 2025
Minnesota Vikings vs Cleveland Browns (Tottenham) [NFLN, 9:30a (ET)/2:30p (BST)]
Also airing on KMSP (FOX/9) in Minneapolis and WEWS (ABC/5) in Cleveland
Announcers: Kenny Albert, Jonathan Vilma, Sara Walsh
The Vikings (2-2) and Browns (1-3) meet in London. Minnesota is 4-0 in England, including a 33-16 win over Cleveland in 2017. Minnesota lost the NFL’s first regular-season outing in Ireland, 24-21 to Pittsburgh at Dublin’s Croke Park in Week 4.
Houston Texans at Baltimore Ravens [CBS, 1:00p (ET)]
Announcers: Ian Eagle, J.J. Watt, Evan Washburn
The Ravens and the Texans, both 1-3, seek a crucial victory in Week 5. Quarterback Lamar Jackson was one of a number of Baltimore starters bitten by the injury bug in a Week 4 loss to Kansas City. Houston got its first win, 26-0 over Tennessee.
Miami Dolphins at Carolina Panthers [FOX, 1:00p (ET)]
Announcers: Eric Collins, Mark Schlereth, Jen Hale
Miami (1-3) visits Carolina (1-3). The Dolphins got on the board with a 27-21 win over the Jets on Monday night in Week 4, but lost star wide receiver Tyreek Hill to a devastating knee injury. The Panthers are 1-0 at home, blanking the Falcons 30-0.
Las Vegas Raiders at Indianapolis Colts [FOX, 1:00p (ET)]
Announcers: Chris Myers, Mark Sanchez, Kristina Pink
Indianapolis (3-1) aims to bounce back by hosting Las Vegas (1-3). Jonathan Taylor (IND) has rushed for 501 yards and five touchdowns across four career games against the Raiders. Taylor led the NFL with 414 rushing yards through four weeks in 2025.
New York Giants at New Orleans Saints [CBS, 1:00p (ET)/12:00p (CT)]
Announcers: Andrew Catalon, Charles Davis, Jason McCourty, AJ Ross
The Giants, sans star wide receiver Malik Nabers, visit the Saints. Nabers sustained a season-ending knee injury in the Giants’ 21-18 victory over the Chargers in Week 4. New Orleans has lost eight straight since winning at New York 14-11 in 2024.
Dallas Cowboys at New York Jets [FOX, 1:00p (ET)]
Announcers: Jason Benetti, Greg Olsen, Pam Oliver
The Cowboys make an additional trip to the Meadowlands to face their rivals’ co-tenants, the Jets. Dallas claimed its first win over New York in 16 years when it defeated the Jets 30-10 in 2023. CeeDee Lamb (DAL) hauled in 11 catches for 143 yards.
Denver Broncos at Philadelphia Eagles [CBS, 1:00p (ET)]
Announcers: Jim Nantz, Tony Romo, Tracy Wolfson
Philadelphia has won three of the four previous meetings with Denver, including a 30-13 victory on Nov. 14, 2021, as DeVonta Smith two receiving TDs.
Tennessee Titans at Arizona Cardinals [CBS, 4:05p (ET)/1:05p (MT)]
Announcers: Spero Dedes, Adam Archuleta, Aditi Kinkhabwala
The Titans resume a run of three straight road games by facing the Cardinals. Tennessee hasn’t won a game in Arizona since 1997, or topped the Cardinals since 2009. Kyler Murray (ARI) threw four TD passes in a 38-13 win over Tennessee in 2021.
Tampa Bay Buccaneers at Seattle Seahawks [CBS, 4:05p (ET)/1:05p (PT)]
Announcers: Kevin Harlan, Trent Green, Melanie Collins
The Buccaneers visit the Seahawks. Tampa Bay is 2-0 on the road in 2025 after wins over Atlanta and Houston. Tom Brady threw two touchdown passes to lead Tampa past Seattle 21-16 at Allianz Arena in Munich on Nov. 13, 2022, during the last meeting.
Detroit Lions at Cincinnati Bengals [FOX, 4:25p (ET)]
Announcers: Kevin Kugler, Daryl Johnston, Allison Williams
The Lions head to the Queen City to battle a Bengals squad still without star Joe Burrow. Detroit has lost seven straight against Cincinnati and defeated the Bengals just once since 1983. Burrow threw three TD passes in a 34-11 Cincy win in 2021.
Washington Commanders at Los Angeles Chargers [FOX, 4:25p (ET)/1:25p (PT)]
Announcers: Kevin Burkhardt, Tom Brady, Erin Andrews, Tom Rinaldi
From SoFi Stadium in Inglewood, Calif.
New England Patriots at Buffalo Bills [NBC, 8:20p (ET)]
Announcers:
NBC, Peacock: Mike Tirico, Cris Collinsworth, Melissa Stark
Universo, TeleXitos: Miguel Gurwitz, Rolando Cantú, Diego Arrioja
The Bills complete a string of three straight at Highmark Stadium by playing the AFC East rival Patriots. The clubs have combined to win the last 16 division titles with Buffalo claiming the past five. The home team has won the last five engagements.
Monday, October 6, 2025
Kansas City Chiefs at Jacksonville Jaguars [ESPN/ABC, 8:15p (ET)]
Announcers:
ESPN, ABC: Joe Buck, Troy Aikman, Lisa Salters, Laura Rutledge
ESPN2: Peyton Manning, Eli Manning
ESPN Deportes: Rebeca Landa, Sebastián Martinez-Christensen, MJ Acosta-Ruiz, John Sutcliffe
The Chiefs (2-2) try for their ninth straight victory over the Jaguars (3-1). Kansas City is 9-3 on Monday Night Football since two-time NFL MVP Patrick Mahomes took over as starting quarterback in 2018. Mahomes has accounted for nine TDs this year.
BYES: Atlanta, Chicago, Green Bay, Pittsburgh
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