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Andre Kalil, MD MPH @drandrekalil.bsky.social · 4d

💥🆕“Plasma Microbial Cell-Free DNA Sequencing in Transplant and Hematologic Patients—Promise, Pitfalls, and Path Forward”
👇Free Access
bit.ly/3KzihEu
@cmijournal.bsky.social #IDSky #MedSky #PCCSky #EMIMC #AMSSky #TxID #meded #Pharmsky #RXSky #MicroSky #ClinMicro @unmc.bsky.social @unmc-id.bsky.social

Plasma microbial cell-free DNA sequencing in transplant and haematologic patients—promise, pitfalls, and path forward

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Andre Kalil, MD MPH @drandrekalil.bsky.social · 16d

Epistemic trespassing

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Reposted by Andre Kalil, MD MPH

UNMC Infectious Diseases Division @unmc-id.bsky.social · 17d

Drs. Gomez, Scherger, Abbas & @drandrekalil.bsky.social published a fascinating paper in @cmijournal.bsky.social on novel diagnostic testing:

"Plasma Microbial Cell-Free DNA Sequencing in Transplant and Hematologic Patients-Promise, Pitfalls, and Path Forward"

pubmed.ncbi.nlm.nih.gov/40946803/

Plasma Microbial Cell-Free DNA Sequencing in Transplant and Hematologic Patients-Promise, Pitfalls, and Path Forward - PubMed

Plasma Microbial Cell-Free DNA Sequencing in Transplant and Hematologic Patients-Promise, Pitfalls, and Path Forward

pubmed.ncbi.nlm.nih.gov

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Reposted by Andre Kalil, MD MPH

CMI Communications @cmicomms.bsky.social · 26d

The 2nd #Communicable & #Breakpoints collaboration drops on 19 Sept! Hosts @angelahuttner.bsky.social & @erinmccreary.bsky.social invite BALANCE trial leads Nick Daneman & Robert Fowler to discuss everything from the trial's humble start to its meteoric impact in clinical practice.
#IDSky #clinmicro

Screenshot of Communicable & Breakpoints hosts Erin McCreary & Angela Huttner with guests Rob Fowler and Nick Daneman.

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Andre Kalil, MD MPH @drandrekalil.bsky.social · 28d

@LancetID.bsky.social

Andre Kalil, MD MPH @drandrekalil.bsky.social · 28d

🆕 “Individualised duration of treatment in febrile urinary tract infection: ready for prime time?”
Excellent article just out by @jesusrbano.bsky.social and Zaira Palacios-Baena @lancetID.bsky.social👇
www.thelancet.com/journals/lan...

Individualised duration of treatment in febrile urinary tract infection: ready for prime time?

The duration of antimicrobial treatment is currently a hot topic in the field of infectious diseases. For decades, the prevailing belief was that long treatments were essential to prevent relapses. Th...

www.thelancet.com

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Reposted by Andre Kalil, MD MPH

UNMC Infectious Diseases Division @unmc-id.bsky.social · Sep 8

Drs. Scherger, Gomez, Abbas, and @drandrekalil.bsky.social paired up for this review in @cmijournal.bsky.social for this narrative review on COVID-19 phenotypes #IDSky

www.clinicalmicrobiologyandinfection.org/article/S119...

Decoding COVID-19: Phenotypes and the Pursuit of Precision Medicine

The pursuit of personalized medicine has underscored the critical role of phenotypes and sub-phenotypes in biology and medicine. A growing body of literature has identified diverse phenotypic manifest...

www.clinicalmicrobiologyandinfection.org

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Reposted by Andre Kalil, MD MPH

ESCMID @escmid.bsky.social · Aug 27

Calls for editorial fellows for ESCMID's two journals, @cmijournal.bsky.social & @cmicomms.bsky.social, are closing soon! Don't miss the chance to be part of shaping and growing the journals and your career!
CMI (due 01 Sept): ow.ly/rifq50WBUfy
CMI Comms (due 15 Sept) ow.ly/F43F50WBUfw

#IDSky

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Reposted by Andre Kalil, MD MPH

Clinical Infectious Diseases @cidjournal.bsky.social · Aug 27

Benefit of Early Oseltamivir Therapy for Adults Hospitalized With Influenza A: An Observational Study

Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare neuroimmunological disorder with diverse etiologies, including infection-associated triggers such as human immunodeficiency virus (HIV) infection.

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Reposted by Andre Kalil, MD MPH

Clinical Infectious Diseases @cidjournal.bsky.social · Aug 24

A Systematic Review and Meta-analysis of the Effectiveness of Remdesivir to Treat SARS-CoV-2 in Hospitalized Patients: Have the Guidelines Evolved With the Evidence?

Clinical practice guidelines (CPGs) aim to reduce variability in practice in order to improve the quality of care by establishing best practice standards [1, 2]. With no definitive standardized approach to developing CPGs, there are inconsistencies in identifying, appraising, and synthesizing...

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Reposted by Andre Kalil, MD MPH

ESCMID @escmid.bsky.social · Aug 10

Our two journals, CMI and CMI Communications, have open calls for editorial fellows. Read more about their respective programmes on their webpages and deadlines:
CMI @cmijournal.bsky.social ow.ly/HTBL50WBUfv
CMI Comms @cmicomms.bsky.social ow.ly/FJkF50WBUfz

#IDSky #clinmicro

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Reposted by Andre Kalil, MD MPH

Abhishek Deshpande MD PhD FIDSA @abhishekdp.bsky.social · Aug 20

Excited to share our work on the epidemiology of diarrheal pathogens using multiplex PCR gastrointestinal panels, led by the amazing medical student, Jeffrey Shu and now published in @cmijournal.bsky.social! 🎉 Kudos to all! #CCLCM #AWSOM shorturl.at/kTWqt

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Reposted by Andre Kalil, MD MPH

Clinical Microbiology and Infection @cmijournal.bsky.social · Aug 24

September 2025 Issue is now online: www.clinicalmicrobiologyandinfection.org/issue/S1198-...

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Reposted by Andre Kalil, MD MPH

Australian Society for Antimicrobials @ausantibiotics.bsky.social · Aug 22

#ASABreakpoint
In vitro, combos look powerful. In practice? Not always.
@angelahuttner.bsky.social reminds us “first, do no harm” Trials show limited benefit + higher toxicity
Are we relying too much on combo therapy in real-world care?
Read: www.asainc.net.au/newsletters/
@gardp.bsky.social #REVIVE

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Reposted by Andre Kalil, MD MPH

Australian Society for Antimicrobials @ausantibiotics.bsky.social · Aug 22

The new #ASA #Breakpoint Newsletter is out🎉
🩺 Chris Robson’s PhD reshaping #infectiveendocarditis care
🔬 AUSCAST guidance on aminopenicillin breakpoints
📊 2024 AGAR: ESBL rates 📈
💊 @angelahuttner.bsky.social antibiotic combos
📷 Photo quiz: #unvaccinated infant
Read: www.asainc.net.au/newsletters

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Reposted by Andre Kalil, MD MPH

Scott Gottlieb, MD @scottgottliebmd.bsky.social · Aug 21

My editorial in JAMA Health Forum: To support the academic research enterprise, we should pursue regulatory reforms that enable institutions to advance more of their discoveries to patients and, in doing so, capture more economic value of innovations they achieve

jamanetwork.com/journals/jam...

Securing America’s Pharmaceutical Innovation Edge

This JAMA Forum discusses challenges to the US’s standing as a global leader in biomedical innovation from China, in the context of recent reductions in funding for biomedical research by the federal ...

jamanetwork.com

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Andre Kalil, MD MPH @drandrekalil.bsky.social · Aug 8

Even though abx are essential for source control from the biological perspective, I would suggest separating them to allow for a more practical & didactic perspective for trainees to address abx timing, type, dosing in an exclusive “cognition lane” distinct from drainage, device removal, surgery.

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Reposted by Andre Kalil, MD MPH

AST IDCOP @ast-idcop.bsky.social · Jul 28

Less than one week until #WTC2025! Will we see you there?? #TxID #IDSky

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Reposted by Andre Kalil, MD MPH

Jonathan Ryder, MD @jonathanrydermd.bsky.social · Jul 17

Excited to be a part of this great group of collaborators on this latest work on blood culture contamination & BCx practices across 52 centers

Tons of credit to Valeria Fabre for leading this group!

#IDSky

journals.asm.org/doi/full/10....

Multicenter evaluation of blood culture contamination and blood cultures practices in US acute care hospitals: time for standardization | Journal of Clinical Microbiology

Blood culture contamination (BCC) is associated with patient harm and unnecessary use of healthcare resources. BCC thresholds have been established; however, multiple BCC definitions exist. There is l...

journals.asm.org

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Andre Kalil, MD MPH @drandrekalil.bsky.social · Jul 17

Congratulations to the guideline panelists for this impressive work and achievement!!
@cortes-penfield.bsky.social @angelahuttner.bsky.social

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Andre Kalil, MD MPH @drandrekalil.bsky.social · Jul 16

Another common reason for meeting futility at the DSMB is the overestimation (clinically unrealistic) of the pre-specified treatment effect.

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Reposted by Andre Kalil, MD MPH

Kelly Cawcutt, MD @kcawcutt.bsky.social · Jul 16

It was such a pleasure to be a part of this manuscript!

Andre Kalil, MD MPH @drandrekalil.bsky.social · May 26

💥🆕“How to approach a patient hospitalized for pneumonia who is not responding to treatment?”
@intenscaremed.bsky.social
👇Free Access
bit.ly/3HdzxNI
#IDSky #MedSky #PCCSky #ICUSky #emimcc #Ansky #EMSky #AMSSky #Pharmsky #Pharmed #RXSky #MicroSky #[email protected]@unmccom.bsky.social

How to approach a patient hospitalized for pneumonia who is not responding to treatment? - Intensive Care Medicine

Pneumonia is a frequent cause of intensive care unit (ICU) admission and is the most common infection in ICU patients across all geographic regions. It takes 48-72h for most patients to respond to app...

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Andre Kalil, MD MPH @drandrekalil.bsky.social · Jul 14

Will do!
Looking forward to working with him!

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Andre Kalil, MD MPH @drandrekalil.bsky.social · Jul 14

Correct - in addition they have no activity (alone or in combination) against endemic mycoses (dimorphic fungi), which are the most common causes of fungal pneumonia.

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Reposted by Andre Kalil, MD MPH

UNMC Infectious Diseases Division @unmc-id.bsky.social · Jul 11

Grab some 🎧 to listen to @drandrekalil.bsky.social!

Andre Kalil, MD MPH @drandrekalil.bsky.social · Jul 3

💥🆕“Management of Pneumonia in the ICU”
Critical Matters podcast I did with the great Dr Sergio Zanotti
👇Free Access
bit.ly/44wOVgb
#IDSky #MedSky #PCCSky #ICUSky #EMIMCC #Ansky #EMSky #AMSSky #TxID #meded #Pharmsky #Pharmed #RXSky #[email protected]@unmc-id.bsky.social @unmccom.bsky.social

Podcast Episode

Hosted by Dr. Sergio Zanotti, CMO of Sound Critical Care, the Critical Matters podcast explores a broad range of topics related to intensive care medicine.

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