Jonathan Ryder, MD
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jonathanrydermd.bsky.social
Jonathan Ryder, MD
@jonathanrydermd.bsky.social
2.3K followers 330 following 610 posts
Adult ID and Assistant Prof at UNMC | Former IUSM IM & Truman State | Abx Stewie, Infxn Prevention, Digital MedEd, Podcasts, Medical History, Reading Non-Fiction, Running/Cycling | Posts are mine
Posts Replies Media Videos
Reposted by Jonathan Ryder, MD
michaelisonmd.bsky.social
So happy to see this paper out after a lot of persistence from Shardul Rathod @hannahnam.bsky.social @ucirvine.bsky.social.

Over a 10 yr period, 6.6% of Flu cases, 12.2% of RSV cases, and 10.9% of PIV cases were Hosp-Acquired. Most in ICH.

onlinelibrary.wiley.com/doi/10.1111/...
Hospital‐Acquired Respiratory Viral Infections (HA‐RVIs) over 10 Years Disproportionally Affect the Immunocompromised
The incidence of HA-Flu/RSV/PIV is associated with patients at high risk of developing RVI complications such as oncology and SCT patients and that most HA cases occur during winter respiratory virus...
onlinelibrary.wiley.com
November 25, 2025 at 10:29 PM
Reposted by Jonathan Ryder, MD
paulsaxmd.bsky.social
Can we really be grateful for anything in the ID world in 2025?

Sure -- plenty of great advances!

Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky
blogs.jwatch.org/hiv-id-obser...
ID Things to Be Grateful for -- 2025 Edition
Looking back on these annual Thanksgiving posts, I notice an odd pattern: every few years, the intro turns into a kind of apology. As in, Yes, I know the title sounds upbeat, please don’t attack me. T...
blogs.jwatch.org
November 25, 2025 at 2:29 AM
Reposted by Jonathan Ryder, MD
idsainfo.bsky.social
New #LetsTalkID out now!🎙️ @matih-id.bsky.social and @drdemetre.bsky.social explore the current state of public health. They discuss how political pressures and weakened infrastructure have left the system vulnerable, and how this could spark a public health “renaissance."

Transcript: bit.ly/4887CZq
From Darkness to Opportunity: Reimagining the Future of Public Health
Mati Hlatshwayo Davis, MD, MPH, FIDSA, and former CDC director Demetre Daskalakis MD, MPH, explore the current state of public health.
bit.ly
November 23, 2025 at 2:11 AM
Reposted by Jonathan Ryder, MD
ashejournal.bsky.social
Continuing #WAAW with opportunities in peripartum stewardship, as discussed in our latest podcast: buff.ly/dbhiyQr where @pamipenem.bsky.social and coauthors discuss how QI work builds momentum (and relationships) in this unique population.
Episode 25: Stewardship Opportunities in Peripartum Infections
In this episode of The ASHE Podcast, host Dr. Priya Nori speaks with Dr. Alexia Foy-Crowder, Dr. Pam Bailey, and Dr. Grace Pazienza about their ASHE paper, “Stewardship opportunities in peripartum inf
soundcloud.com
November 23, 2025 at 4:08 PM
Reposted by Jonathan Ryder, MD
sheaepi.bsky.social
In the latest episode of The ASHE Podcast, Dr. Priya Nori speaks with the authors of a new paper in ASHE, "Stewardship opportunities in peripartum infections: a review of quality improvement initiatives and future directions".

bit.ly/4rfM8CG
November 21, 2025 at 9:55 PM
Reposted by Jonathan Ryder, MD
paulsaxmd.bsky.social
Inspired by this rage-inducing ad, I offer 3 big misses on antibiotics that need to die.
paulsaxmd.substack.com/p/three-myth...
Three Myths About Antibiotics We Really Need to Retire
Sneezes, penicillin allergies, and those strangely sacred 5- and 7-day courses.
paulsaxmd.substack.com
November 21, 2025 at 3:53 PM
Reposted by Jonathan Ryder, MD
trubianojason.bsky.social
Is one dose ever enough? The PROSPECTOR 🪓 Trial will answer - A international double blind placebo controlled trial of 1 dose vs 5 day for #penicillinallergy. This week we recruited our 100th patient! 🎉 @thedohertyinst.bsky.social
November 21, 2025 at 11:04 AM
Reposted by Jonathan Ryder, MD
trubianojason.bsky.social
The largest adult #penicillinallergy study ever undertaken - The iNAAN study @thedohertyinst.bsky.social @unimelb.bsky.social - 52 hospitals, 8 countries and over 5000 patients….Real world proof of the safety and effectiveness of inpatient DOC! Stay tuned #AMS folks 👀Results soon!
November 21, 2025 at 11:50 PM
jonathanrydermd.bsky.social
CDC 1946-2025: R.I.P.
open.substack.com/pub/pauloffi...
CDC 1946-2025: R.I.P.
Robert F. Kennedy Jr. has now weaponized the CDC website to promote his anti-vaccine views
open.substack.com
November 21, 2025 at 5:19 AM
Reposted by Jonathan Ryder, MD
idsainfo.bsky.social
Decades of rigorous and scientifically sound research have proven that vaccines do not cause autism. CDC’s decision to change language on its website reversing that finding is reckless & harmful.

Our statement w/ @hivma.bsky.social, APIC, @sheaepi.bsky.social & @sidpharm.bsky.social: bit.ly/3XEc0KH
November 21, 2025 at 12:42 AM
Reposted by Jonathan Ryder, MD
boghuma.bsky.social
A new NEJM paper just dropped evaluating a quadrivalent modified mRNA (modRNA) influenza vaccine in a phase 3 trial. This is the largest test yet of whether the mRNA platform that transformed COVID-19 vaccination can improve our fight against flu.
www.nejm.org/doi/full/10....
Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine | NEJM
Influenza remains a major health burden despite the use of licensed vaccines. Nucleoside-modified messenger RNA (modRNA) influenza vaccines have shown promising immunogenicity against influenza and...
www.nejm.org
November 20, 2025 at 12:26 PM
Reposted by Jonathan Ryder, MD
uwidfellowship.bsky.social
Modified mRNA vaccine non-inferior *and* superior to usual quadravalent influenza vaccine in this RCT of 18.5K people during 2022/2023 flu season, relative efficacy 34.5%.

mRNA vaccine with increased local and systemic reactions, AEs similar… #IDSky #vaccines

www.nejm.org/doi/full/10....
Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine | NEJM
Influenza remains a major health burden despite the use of licensed vaccines. Nucleoside-modified messenger RNA (modRNA) influenza vaccines have shown promising immunogenicity against influenza and...
www.nejm.org
November 19, 2025 at 11:21 PM
Reposted by Jonathan Ryder, MD
febrilepodcast.com
Our newest episode features Drs. Raghad Al-Abdwani, Badriya Al Adawi, and Zaid Al Hinai discussing "A Critical Query"! #Idsky
November 19, 2025 at 4:58 PM
Reposted by Jonathan Ryder, MD
absteward.bsky.social
🆕🔥🦴 Our 2025 Update to @wiki-guidelines.bsky.social for the Management of Pyogenic Osteomyelitis in Adults 🌟 @bradspellberg.bsky.social
🔗 [link] #idsky
www.amjmed.com/article/S000...
November 19, 2025 at 4:25 PM
Reposted by Jonathan Ryder, MD
firstlineorg.bsky.social
The next #MedEd game for #WAAW2025 is here! Can you find the four groups of four items that belong together? 🧩🤔

Play Infectious Connections today: connections.firstline.org

Discover the engaging educational content crafted by Shaqil Peermohamed, MD! #IDSky #PharmSky #AMSSKy
November 17, 2025 at 2:26 PM
Reposted by Jonathan Ryder, MD
sheaepi.bsky.social
USAAW urges proper antibiotic & antifungal use to protect people, animals, plants & our environment. This year’s theme, Fighting Antimicrobial Resistance Takes All of Us, reminds us our health is connected. Together we can improve prescribing and fight antimicrobial resistance.
November 18, 2025 at 3:26 PM
Reposted by Jonathan Ryder, MD
uwidfellowship.bsky.social
Trying to remember which bacteria have bipolar staining? Love this slide from @iuidfellowship.bsky.social
- Yersinia pestis
- Vibrio parahemolyticus
- Burkholderia mallei and pseudomallei
- Haemophilus ducreyi
- Klebsiella granulomatis
#IDSky
November 18, 2025 at 12:55 AM
Reposted by Jonathan Ryder, MD
kristadgens.bsky.social
📢 Excited to announce our new research is now published in the JIC! 🎉

🔍 What were we seeing? 3 g of cefazolin for cellulitis in obese patients.
🚪 Why DOOR? It combines efficacy and safety outcomes.
💡 What did we find? 3 g might be a good idea.

lnkd.in/gbP4sx_7

@ebhirsch.bsky.social
November 17, 2025 at 5:11 PM
Reposted by Jonathan Ryder, MD
josephmarcusid.medsky.social
Fascinating article on the history of syphilis:

“English people called it the
“Spanish disease”… the Spanish called it mal inglés.
The Dutch called it “Spanish smallpox”
The Russians blamed the Poles, and the Turks referred to it as the “Christian disease””

#IDSky

academic.oup.com/jid/advance-...
Syphilis Transmission: Contagion of Bodies and Words
Syphilis, infection caused by Treponema pallidum, occurred in Naples and in Europe in the late 15th century impacting on people’s lives. Here, we explored
academic.oup.com
November 16, 2025 at 3:56 AM
Reposted by Jonathan Ryder, MD
unmc.bsky.social
Congratulations to Hemant Roy, MD, on his appointment as the new chair of the UNMC Department of Internal Medicine!

More:
www.unmc.edu/newsroom/202...
Hemant Roy, MD, announced as internal medicine chair
Dr. Roy, currently at Ben Taub Hospital and Baylor College of Medicine, is a former UNMC faculty member with demonstrated expertise.
www.unmc.edu
November 14, 2025 at 6:08 PM
Reposted by Jonathan Ryder, MD
sundermannaj.bsky.social
Our new paper out: AI boosted our genomic surveillance investigations by finding 37 missed transmission routes and reaching >90% sensitivity in key scenarios.

AI + WGS can speed outbreak reviews and help IP teams act faster #IDSky

Genomic surveillance is a key must!

📃: doi.org/10.1017/ice....
November 14, 2025 at 3:09 PM
Reposted by Jonathan Ryder, MD
maebhnif.bsky.social
"Rather than democratizing scientific publishing, Open Access has helped commercial publishers generate more profits (publishers found ways to shift paywalls from readers to authors). More stringent reforms are required to tackle misaligned drivers of scientific publishing."
Fernanda Beigel et al.
madhupai.bsky.social Madhu Pai, MD, PhD @madhupai.bsky.social · 12d
The Drain of Scientific Publishing

arxiv.org/pdf/2511.04820
November 14, 2025 at 2:19 PM
Reposted by Jonathan Ryder, MD
sidpharm.bsky.social
Dr. Julie Ann Justo is joined by experts Drs. Krista Gens and Javier A. Villafuerte Gálvez as they dive deep into the gut microbiome to explore the latest therapeutic frontier for C. difficile infections. This podcast was supported by an unrestricted grant from Nestlé Health Science sidp.pinecast.co
November 14, 2025 at 10:01 AM
jonathanrydermd.bsky.social
Highly recommend signing up for the Advance-ID bacterial and fungal infections newsletter. Thorough review of literature over past 2 weeks including critical analysis of RCTs. #IDSky

www.advance-id.network

forms.cloud.microsoft/pages/respon...
Microsoft Forms
forms.cloud.microsoft
November 14, 2025 at 3:22 PM
jonathanrydermd.bsky.social
We already know ESR/CRP are zombie tests...this SRMA suggests that their role in the definition of PJI is questionable given their lack of sensitivity/specificity, etc. Same with other inflammatory markers like IL-6
November 14, 2025 at 3:05 PM