Interests: Getting trainees excited about ID/Research, ECMO infections, STIs, and Transfusion-Transmitted Infections
https://scholar.usuhs.edu/en/persons/joseph-marcus
The joint infection panel which normally runs synovial fluid. 🤯
#IDSky
academic.oup.com/cid/advance-...
The joint infection panel which normally runs synovial fluid. 🤯
#IDSky
academic.oup.com/cid/advance-...
-the history of contact precautions
-the need for balance ⚖️ between the benefits of gowns/gloves with their cost/environmental impact
www.cambridge.org/core/journal...
#IDSky
-the history of contact precautions
-the need for balance ⚖️ between the benefits of gowns/gloves with their cost/environmental impact
www.cambridge.org/core/journal...
#IDSky
❌Only 56% had follow-up testing within 1 year (compared to 78% of women)
❌16% with STI in 3 years (24% of women)
✅0 cases of HIV
www.health.mil/News/Article...
#IDSky
❌Only 56% had follow-up testing within 1 year (compared to 78% of women)
❌16% with STI in 3 years (24% of women)
✅0 cases of HIV
www.health.mil/News/Article...
#IDSky
In this paper led by a USUHS Med student, we anonymized contact tracing forms for those with CT with several important findings:
www.health.mil/News/Article...
#IDSky
In this paper led by a USUHS Med student, we anonymized contact tracing forms for those with CT with several important findings:
www.health.mil/News/Article...
#IDSky
(single dose Ampho +14 days of 1200 fluconazole + 100mg/kg flucytosine) cryptococcal meningitis treatment at LA county 🏥:
-Higher completion w/o adverse effect (76% vs 35% in conventional dosing)
-Significantly less pts leaving AMA
#IDSky
jamanetwork.com/journals/jam...
(single dose Ampho +14 days of 1200 fluconazole + 100mg/kg flucytosine) cryptococcal meningitis treatment at LA county 🏥:
-Higher completion w/o adverse effect (76% vs 35% in conventional dosing)
-Significantly less pts leaving AMA
#IDSky
jamanetwork.com/journals/jam...
www.science.org/doi/10.1126/... #IDSky
www.science.org/doi/10.1126/... #IDSky
IDSA Team on why they pulled out of guidelines: academic.oup.com/cid/advance-...
ATS Team response: academic.oup.com/cid/advance-...
This is certainly a peek behind the curtain of how guidelines get made
#IDSky
IDSA Team on why they pulled out of guidelines: academic.oup.com/cid/advance-...
ATS Team response: academic.oup.com/cid/advance-...
This is certainly a peek behind the curtain of how guidelines get made
#IDSky
This 🇳🇱 case study denonstrated “9.6-fold lower dolutegravir, 1.5-fold lower tenofovir and 1.7-fold higher lamivudine exposure as compared to reference populations.”
#IDSky
bpspubs.onlinelibrary.wiley.com/doi/abs/10.1...
This 🇳🇱 case study denonstrated “9.6-fold lower dolutegravir, 1.5-fold lower tenofovir and 1.7-fold higher lamivudine exposure as compared to reference populations.”
#IDSky
bpspubs.onlinelibrary.wiley.com/doi/abs/10.1...
“Of 503 patients with ≥1 blood culture collected after FN day 3, 19 (4%) had a new BSI after FN day 3”
Authors suggest low utility of repeat BCx after day 3
#IDSky
academic.oup.com/cid/advance-...
“Of 503 patients with ≥1 blood culture collected after FN day 3, 19 (4%) had a new BSI after FN day 3”
Authors suggest low utility of repeat BCx after day 3
#IDSky
academic.oup.com/cid/advance-...
#FOAMcc #FOAMecmo
🔗 rdcu.be/eZd0g
🔍 Delphi study involving 39 international #ECLS experts
definition
🩺 suspicion & methodology for diagnosis
🧫 bacteriology
💉 treatment & treatment failure
⚠️ preventive measures
#FOAMcc #FOAMecmo
🔗 rdcu.be/eZd0g
#FOAMcc #FOAMecmo
🔗 rdcu.be/eZd0g
academic.oup.com/ofid/issue/1...
#IDSky
academic.oup.com/ofid/issue/1...
#IDSky
Requires symptoms (➕ skin swabs culture🙅♂️🟰 infection)
✅ send cultures if signs of infection
❌ antimicrobial ppx or digestive decontamination
#IDSky
link.springer.com/article/10.1...
Requires symptoms (➕ skin swabs culture🙅♂️🟰 infection)
✅ send cultures if signs of infection
❌ antimicrobial ppx or digestive decontamination
#IDSky
link.springer.com/article/10.1...
4,555 referred
244 (5.4%) w/ bite/scratch
4 (0.09%) wild mammals (2 🐀, 1 🦝, 1 porcupine)
Extrapolating 🇺🇸 donors:
~ 881 bite/scratch
~12 wild exposure
#IDSky
wwwnc.cdc.gov/eid/article/...
#IDSky
4,555 referred
244 (5.4%) w/ bite/scratch
4 (0.09%) wild mammals (2 🐀, 1 🦝, 1 porcupine)
Extrapolating 🇺🇸 donors:
~ 881 bite/scratch
~12 wild exposure
#IDSky
wwwnc.cdc.gov/eid/article/...
#IDSky
Sadly limited descriptions of tropical infections, but in this review we summarize the literature.
link.springer.com/article/10.1...
#IDSky
Sadly limited descriptions of tropical infections, but in this review we summarize the literature.
link.springer.com/article/10.1...
#IDSky
Learn more and secure your spot today: https://bit.ly/48YuVoP
Learn more and secure your spot today: https://bit.ly/48YuVoP
Human Guinea worm cases by year:
1983 - 3.5 million
2024 - 15 cases
Jan-Jun 2025- 1 case
Many non-medical challenges until complete eradication
#IDSky
www.cdc.gov/mmwr/volumes...
#IDSky
Human Guinea worm cases by year:
1983 - 3.5 million
2024 - 15 cases
Jan-Jun 2025- 1 case
Many non-medical challenges until complete eradication
#IDSky
www.cdc.gov/mmwr/volumes...
#IDSky
💉 PK/PD concepts & considerations
🧫 antibacterials
🍄 antifungals
🦠 antivirals
🩺 management recommendations: dose optimization, challenges/recommendations, ABT stewardship
🔓 bit.ly/45vjrbt
💉 PK/PD concepts & considerations
🧫 antibacterials
🍄 antifungals
🦠 antivirals
🩺 management recommendations: dose optimization, challenges/recommendations, ABT stewardship
🔓 bit.ly/45vjrbt
Blood banks use PCR which can be positive for months to years after infection.
Guidance is to 🚫not treat unless positive smear
doi.org/10.1093/cid/...
Blood banks use PCR which can be positive for months to years after infection.
Guidance is to 🚫not treat unless positive smear
doi.org/10.1093/cid/...
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
-Similar rate of viral suppression (VL<50)
-Similar effect on CD4 count
Likely one step closer to a weekly oral HIV med.
#IDSky
www.acpjournals.org/doi/10.7326/...
-Similar rate of viral suppression (VL<50)
-Similar effect on CD4 count
Likely one step closer to a weekly oral HIV med.
#IDSky
www.acpjournals.org/doi/10.7326/...
African Trypanosomiasis: 🇬🇳 🇰🇪
Malaria: 🇬🇪 🇸🇷 🇹🇱
MTCT HBV: 🇲🇻
Onchocerciasis: 🇳🇪
Trachoma: 🇧🇮🇪🇬🇲🇷 🇵🇬
#IDSky
🇨🇻 🇪🇬-Malaria
🇧🇷 🇹🇱 - Lymphatic filariasis
🇯🇴-Leprosy
🇹🇩-African Trypanosomiasis
🇵🇰 🇮🇳 🇻🇳- Trachoma
www.npr.org/sections/goa...
#IDSky
African Trypanosomiasis: 🇬🇳 🇰🇪
Malaria: 🇬🇪 🇸🇷 🇹🇱
MTCT HBV: 🇲🇻
Onchocerciasis: 🇳🇪
Trachoma: 🇧🇮🇪🇬🇲🇷 🇵🇬
#IDSky
#IDSky
www.who.int/news/item/18...
#IDSky
www.who.int/news/item/18...
Comparison: abx targeting unblinded 🦴 cx or ulcer cx
Outcome: Remission at 12 months
Outcome: No difference RR 1.13; (95% CI 0.80-1.60).
Why? Both cxs concordant 85% of time
#IDSky
doi.org/10.1093/cid/...
Comparison: abx targeting unblinded 🦴 cx or ulcer cx
Outcome: Remission at 12 months
Outcome: No difference RR 1.13; (95% CI 0.80-1.60).
Why? Both cxs concordant 85% of time
#IDSky
doi.org/10.1093/cid/...