Paul Adamson MD MPH
@padamsonmd.bsky.social
ID doc and researcher. Asst Professor at UCLA. Interests in HIV, sexually transmitted infections, global health, & AMR. 🇲🇽|🇺🇸 He/him. Views are mine.
Pinned
Cefixime for the Treatment of Neisseria gonorrhoeae Infections in a Setting With Increased Antimicrobial Resistance: A Retrospective Study in Hanoi, Vietnam
In Vietnam, cefixime effectively treated rectal and urethral gonococcal infections but showed higher pharyngeal NAAT positivity at test of cure (TOC) compa
academic.oup.com
#Cefixime is an alternative treatment for #gonorrhea, typically when #ceftriaxone isn’t available or feasible, but clinical data are limited, esp in areas w/ high #AMR
Here, we report outcomes from patients treated with cefixime in Hanoi 🇻🇳
🔗 academic.oup.com/cid/article/...
#STIsky #IDsky
1/
Here, we report outcomes from patients treated with cefixime in Hanoi 🇻🇳
🔗 academic.oup.com/cid/article/...
#STIsky #IDsky
1/
Reposted by Paul Adamson MD MPH
As always @holdenthorp.bsky.social hits the nail on the head. Deprioritizing discovery science stifles innovation & means less US created intellectual property. How-and will-US biosciences recover? @idsainfo.bsky.social @csis.org
Marcia McNutt has been saying that the US is doing a huge experiment with China as the control. The global scientific community will still produce knowledge. But not being in the lead has bad implications for US flourishing. My column:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
America is ceding the lead in creating the future
The renowned American management consultant and author Peter Drucker is often credited as saying that “the best way to predict the future is to create it”—a view that applies to science as much as to ...
www.science.org
February 10, 2026 at 12:33 PM
As always @holdenthorp.bsky.social hits the nail on the head. Deprioritizing discovery science stifles innovation & means less US created intellectual property. How-and will-US biosciences recover? @idsainfo.bsky.social @csis.org
Reposted by Paul Adamson MD MPH
The Journal of Infectious Diseases has just released a special collection of papers devoted to "Contemporary Research on #AMR", covering mechanisms of resistance and virulence, pharmacokinetics, drug development, and wastewater surveillance
@jidjournal.bsky.social
#IDEpi #MedSky #IDSky #AMS
@jidjournal.bsky.social
#IDEpi #MedSky #IDSky #AMS
Validate User
academic.oup.com
February 10, 2026 at 5:44 AM
Reposted by Paul Adamson MD MPH
The Trump admin says cutting $600M in CDC health grants from four Democratic-led states “reflects agency priorities.” Those priorities now exclude HIV prevention, outbreak readiness, and care for marginalized communities—mid-measles surge.
Tell us who this helps. Because it’s not the public. 1/2
Tell us who this helps. Because it’s not the public. 1/2
Trump Administration to Cut $600 Million in Health Funding From Four States
www.nytimes.com
February 10, 2026 at 7:40 AM
The Trump admin says cutting $600M in CDC health grants from four Democratic-led states “reflects agency priorities.” Those priorities now exclude HIV prevention, outbreak readiness, and care for marginalized communities—mid-measles surge.
Tell us who this helps. Because it’s not the public. 1/2
Tell us who this helps. Because it’s not the public. 1/2
Reposted by Paul Adamson MD MPH
Recent locally acquired clade Ib mpox cases in multiple countries signal a shift in transmission and spread. Here we highlight key questions and gaps in our preparedness
#IDsky
#Episky
#mpox
www.thelancet.com/journals/lan...
#IDsky
#Episky
#mpox
www.thelancet.com/journals/lan...
Circulation of clade Ib mpox outside of Africa—are we prepared?
Mpox is a spectrum of disease caused by monkeypox virus, which is divided into clades
I (with subclades Ia and Ib) and II (with subclades IIa and IIb).1 In 2022, simultaneous
detection of non-travel-a...
www.thelancet.com
February 9, 2026 at 5:27 PM
Recent locally acquired clade Ib mpox cases in multiple countries signal a shift in transmission and spread. Here we highlight key questions and gaps in our preparedness
#IDsky
#Episky
#mpox
www.thelancet.com/journals/lan...
#IDsky
#Episky
#mpox
www.thelancet.com/journals/lan...
Reposted by Paul Adamson MD MPH
#IDSky I always email residents rotating with me survival tips for their time of the ID consult service. I like to keep this short and high yield but I am constantly editing and improving the tip sheet. What would you add or remove. It cannot be longer that one page 😊.
February 8, 2026 at 10:31 PM
#IDSky I always email residents rotating with me survival tips for their time of the ID consult service. I like to keep this short and high yield but I am constantly editing and improving the tip sheet. What would you add or remove. It cannot be longer that one page 😊.
Reposted by Paul Adamson MD MPH
🧪 🦠 💉 #measles encephalitis - awful, preventable #VaccinesWork
Great to see that the #PublicHealth response is also being reported here
„Over 7,000 more doses of the MMR vaccine were given statewide in South Carolina this January compared to January 2025, a 72 percent increase“
archive.ph/KdrD7
Great to see that the #PublicHealth response is also being reported here
„Over 7,000 more doses of the MMR vaccine were given statewide in South Carolina this January compared to January 2025, a 72 percent increase“
archive.ph/KdrD7
February 5, 2026 at 6:11 AM
🧪 🦠 💉 #measles encephalitis - awful, preventable #VaccinesWork
Great to see that the #PublicHealth response is also being reported here
„Over 7,000 more doses of the MMR vaccine were given statewide in South Carolina this January compared to January 2025, a 72 percent increase“
archive.ph/KdrD7
Great to see that the #PublicHealth response is also being reported here
„Over 7,000 more doses of the MMR vaccine were given statewide in South Carolina this January compared to January 2025, a 72 percent increase“
archive.ph/KdrD7
Reposted by Paul Adamson MD MPH
✨ Only 10 days left to apply for the #AIDS2026 Prevention Ambassador Fellowship!
Selected fellows will:
🔹 Lead a digital #HIV prevention content project
🔹 Attend AIDS 2026
🔹 Expand their networks
👉 Apply by 15 February: zurl.co/qj5IL
#RethinkRebuildRise
Selected fellows will:
🔹 Lead a digital #HIV prevention content project
🔹 Attend AIDS 2026
🔹 Expand their networks
👉 Apply by 15 February: zurl.co/qj5IL
#RethinkRebuildRise
February 5, 2026 at 11:08 AM
✨ Only 10 days left to apply for the #AIDS2026 Prevention Ambassador Fellowship!
Selected fellows will:
🔹 Lead a digital #HIV prevention content project
🔹 Attend AIDS 2026
🔹 Expand their networks
👉 Apply by 15 February: zurl.co/qj5IL
#RethinkRebuildRise
Selected fellows will:
🔹 Lead a digital #HIV prevention content project
🔹 Attend AIDS 2026
🔹 Expand their networks
👉 Apply by 15 February: zurl.co/qj5IL
#RethinkRebuildRise
Reposted by Paul Adamson MD MPH
🔴🚨 FINAL SESSION IS LIVE at #ACC2026
Title: Access isn’t the end, it’s the beginning.
Our closing panel takes on the purpose of antimicrobial innovation, and what must come after access.
🔴 WATCH IT LIVE NOW: portalapp.bsac.eventsair.com/VirtualAtten...
Title: Access isn’t the end, it’s the beginning.
Our closing panel takes on the purpose of antimicrobial innovation, and what must come after access.
🔴 WATCH IT LIVE NOW: portalapp.bsac.eventsair.com/VirtualAtten...
February 5, 2026 at 11:12 AM
🔴🚨 FINAL SESSION IS LIVE at #ACC2026
Title: Access isn’t the end, it’s the beginning.
Our closing panel takes on the purpose of antimicrobial innovation, and what must come after access.
🔴 WATCH IT LIVE NOW: portalapp.bsac.eventsair.com/VirtualAtten...
Title: Access isn’t the end, it’s the beginning.
Our closing panel takes on the purpose of antimicrobial innovation, and what must come after access.
🔴 WATCH IT LIVE NOW: portalapp.bsac.eventsair.com/VirtualAtten...
Reposted by Paul Adamson MD MPH
Grateful to have the opportunity to share this little piece of my heart. Love is always the answer.
academic.oup.com/cid/advance-...
academic.oup.com/cid/advance-...
February 3, 2026 at 5:01 PM
Grateful to have the opportunity to share this little piece of my heart. Love is always the answer.
academic.oup.com/cid/advance-...
academic.oup.com/cid/advance-...
Reposted by Paul Adamson MD MPH
Cefixime for the Treatment of Neisseria gonorrhoeae Infections in a Setting With Increased Antimicrobial Resistance: A Retrospective Study in Hanoi, Vietnam
📚 In Issue
🔗 https://bit.ly/4a6VNn5
📚 In Issue
🔗 https://bit.ly/4a6VNn5
February 1, 2026 at 11:35 PM
Cefixime for the Treatment of Neisseria gonorrhoeae Infections in a Setting With Increased Antimicrobial Resistance: A Retrospective Study in Hanoi, Vietnam
📚 In Issue
🔗 https://bit.ly/4a6VNn5
📚 In Issue
🔗 https://bit.ly/4a6VNn5
Reposted by Paul Adamson MD MPH
February 2, 2026 at 10:29 PM
Reposted by Paul Adamson MD MPH
"No country can prevent or manage a pandemic alone."
This is such a familiar refrain that it almost makes me nostalgic.
www.who.int/news/item/02...
This is such a familiar refrain that it almost makes me nostalgic.
www.who.int/news/item/02...
Six years after COVID-19’s global alarm: Is the world better prepared for the next pandemic?
Six years ago, the Director-General of the World Health Organization sounded the highest global alarm available under international law at the time, declaring the outbreak of a new coronavirus diseas...
www.who.int
February 3, 2026 at 10:15 AM
"No country can prevent or manage a pandemic alone."
This is such a familiar refrain that it almost makes me nostalgic.
www.who.int/news/item/02...
This is such a familiar refrain that it almost makes me nostalgic.
www.who.int/news/item/02...
Reposted by Paul Adamson MD MPH
New from @cidrap.bsky.social: Part 2 of my series on persistent vaccine myths.
This one covers vaccines and autism, VAERS misuse, "the flu shot gave me the flu," and mRNA/turbo cancer claims.
www.cidrap.umn.edu/childhood-va...
This one covers vaccines and autism, VAERS misuse, "the flu shot gave me the flu," and mRNA/turbo cancer claims.
www.cidrap.umn.edu/childhood-va...
CIDRAP Op-ed: Vaccine myths that won’t die and how to counter them—part 2
www.cidrap.umn.edu
January 16, 2026 at 5:34 PM
New from @cidrap.bsky.social: Part 2 of my series on persistent vaccine myths.
This one covers vaccines and autism, VAERS misuse, "the flu shot gave me the flu," and mRNA/turbo cancer claims.
www.cidrap.umn.edu/childhood-va...
This one covers vaccines and autism, VAERS misuse, "the flu shot gave me the flu," and mRNA/turbo cancer claims.
www.cidrap.umn.edu/childhood-va...
Reposted by Paul Adamson MD MPH
CIDRAP Op-ed: Vaccine myths that won’t die and how to counter them—part 2
by @jakescottMD
Today's myths include "Vaccines cause autism," "VAERS proves vaccines kill people," "Natural immunity is better," and "mRNA vaccines cause turbo cancers."
www.cidrap.umn.edu/c...
by @jakescottMD
Today's myths include "Vaccines cause autism," "VAERS proves vaccines kill people," "Natural immunity is better," and "mRNA vaccines cause turbo cancers."
www.cidrap.umn.edu/c...
January 16, 2026 at 5:13 PM
CIDRAP Op-ed: Vaccine myths that won’t die and how to counter them—part 2
by @jakescottMD
Today's myths include "Vaccines cause autism," "VAERS proves vaccines kill people," "Natural immunity is better," and "mRNA vaccines cause turbo cancers."
www.cidrap.umn.edu/c...
by @jakescottMD
Today's myths include "Vaccines cause autism," "VAERS proves vaccines kill people," "Natural immunity is better," and "mRNA vaccines cause turbo cancers."
www.cidrap.umn.edu/c...
This is a great @cidjournal.bsky.social supplement for all you #gonorrhea, #STI, and #AMR enthusiasts. Or for anyone who’s heard about drug-resistant gonorrhea and wants to learn more.
Will link articles in 🧵 below - check it out and share! #openaccess
#IDsky #STIsky
bsky.app/profile/carb...
Will link articles in 🧵 below - check it out and share! #openaccess
#IDsky #STIsky
bsky.app/profile/carb...
📘 New publication supported by CARB-X!
A new supplement in Oxford University Press Clinical Infectious Diseases highlights why treatment diversification is essential to address rising drug resistance in N. gonorrhoeae. #IDSky 🧪
🔗 Read here: bit.ly/45KVg90
A new supplement in Oxford University Press Clinical Infectious Diseases highlights why treatment diversification is essential to address rising drug resistance in N. gonorrhoeae. #IDSky 🧪
🔗 Read here: bit.ly/45KVg90
January 16, 2026 at 12:44 AM
This is a great @cidjournal.bsky.social supplement for all you #gonorrhea, #STI, and #AMR enthusiasts. Or for anyone who’s heard about drug-resistant gonorrhea and wants to learn more.
Will link articles in 🧵 below - check it out and share! #openaccess
#IDsky #STIsky
bsky.app/profile/carb...
Will link articles in 🧵 below - check it out and share! #openaccess
#IDsky #STIsky
bsky.app/profile/carb...
Which #penA alleles are driving ceftriaxone resistance in #gonorrhea in the Asia-Pacific? Examining data from Cambodia, Vietnam, and China, we show the importance of penA-60 and identify penA-237 as an emerging allele of interest in the region
#IDSky #STIsky #AMR
🔗: academic.oup.com/cid/article/...
#IDSky #STIsky #AMR
🔗: academic.oup.com/cid/article/...
PenA Alleles Associated With Gonococcal Ceftriaxone Resistance in Cambodia, China, and Vietnam
AbstractBackground. The global dissemination of ceftriaxone-resistant Neisseria gonorrhoeae, primarily associated with mosaic penA alleles, threatens the e
academic.oup.com
January 15, 2026 at 11:45 PM
Which #penA alleles are driving ceftriaxone resistance in #gonorrhea in the Asia-Pacific? Examining data from Cambodia, Vietnam, and China, we show the importance of penA-60 and identify penA-237 as an emerging allele of interest in the region
#IDSky #STIsky #AMR
🔗: academic.oup.com/cid/article/...
#IDSky #STIsky #AMR
🔗: academic.oup.com/cid/article/...
Reposted by Paul Adamson MD MPH
New publication! Comparing Strategies to Introduce Two New Antibiotics for Gonorrhea: A Modeling Study featuring authors: @mckline98.bsky.social, @kroster.bsky.social, @dhelekal.bsky.social, @rumpl-er.bsky.social, and @yhgrad.bsky.social. Read it here at bit.ly/3Z1Zplh
Comparing Strategies to Introduce Two New Antibiotics for Gonorrhea: A Modeling Study
Immediately introducing 2 new antibiotics to treat gonorrhea alongside 1 currently used therapy is more effective at minimizing drug resistance than holdin
bit.ly
January 9, 2026 at 3:38 PM
New publication! Comparing Strategies to Introduce Two New Antibiotics for Gonorrhea: A Modeling Study featuring authors: @mckline98.bsky.social, @kroster.bsky.social, @dhelekal.bsky.social, @rumpl-er.bsky.social, and @yhgrad.bsky.social. Read it here at bit.ly/3Z1Zplh
Reposted by Paul Adamson MD MPH
@idweek.bsky.social abstracts have just been posted online on @ofidjournal.bsky.social
academic.oup.com/ofid/issue/1...
#IDSky
academic.oup.com/ofid/issue/1...
#IDSky
Volume 13 Issue Supplement_1 | Open Forum Infectious Diseases | Oxford Academic
An official journal of the Infectious Diseases Society of America. Publishes clinical, translational, and basic research findings focusing on the intersection of biomedical science and clinical practi...
academic.oup.com
January 13, 2026 at 3:05 AM
@idweek.bsky.social abstracts have just been posted online on @ofidjournal.bsky.social
academic.oup.com/ofid/issue/1...
#IDSky
academic.oup.com/ofid/issue/1...
#IDSky
#Cefixime is an alternative treatment for #gonorrhea, typically when #ceftriaxone isn’t available or feasible, but clinical data are limited, esp in areas w/ high #AMR
Here, we report outcomes from patients treated with cefixime in Hanoi 🇻🇳
🔗 academic.oup.com/cid/article/...
#STIsky #IDsky
1/
Here, we report outcomes from patients treated with cefixime in Hanoi 🇻🇳
🔗 academic.oup.com/cid/article/...
#STIsky #IDsky
1/
Cefixime for the Treatment of Neisseria gonorrhoeae Infections in a Setting With Increased Antimicrobial Resistance: A Retrospective Study in Hanoi, Vietnam
In Vietnam, cefixime effectively treated rectal and urethral gonococcal infections but showed higher pharyngeal NAAT positivity at test of cure (TOC) compa
academic.oup.com
January 13, 2026 at 10:32 PM
#Cefixime is an alternative treatment for #gonorrhea, typically when #ceftriaxone isn’t available or feasible, but clinical data are limited, esp in areas w/ high #AMR
Here, we report outcomes from patients treated with cefixime in Hanoi 🇻🇳
🔗 academic.oup.com/cid/article/...
#STIsky #IDsky
1/
Here, we report outcomes from patients treated with cefixime in Hanoi 🇻🇳
🔗 academic.oup.com/cid/article/...
#STIsky #IDsky
1/
Interesting report of a #gonorrhea FC428 strain with #penA60 in Ontario w/ elevated ceftriaxone MIC. Fortunately, cleared w/ 500mg CRO.
The infection was apparently non-travel related, suggesting infections might be circulating in some local settings.
#STIsky #AMR
www.canada.ca/en/public-he...
The infection was apparently non-travel related, suggesting infections might be circulating in some local settings.
#STIsky #AMR
www.canada.ca/en/public-he...
Detection of non-travel-associated, ceftriaxone non-susceptible Neisseria gonorrhoeae FC428-like harbouring the mosaic penA60 allele - Canada.ca
First known case of ceftriaxone non-susceptible N. gonorrhoeae FC428 infection with the mosaic penA60 allele identified in an Ontario patient
www.canada.ca
December 23, 2025 at 1:37 AM
Interesting report of a #gonorrhea FC428 strain with #penA60 in Ontario w/ elevated ceftriaxone MIC. Fortunately, cleared w/ 500mg CRO.
The infection was apparently non-travel related, suggesting infections might be circulating in some local settings.
#STIsky #AMR
www.canada.ca/en/public-he...
The infection was apparently non-travel related, suggesting infections might be circulating in some local settings.
#STIsky #AMR
www.canada.ca/en/public-he...
Reposted by Paul Adamson MD MPH
🧵 Essential ID Papers for 2025: A Clinician’s Guide
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
December 22, 2025 at 3:22 PM
🧵 Essential ID Papers for 2025: A Clinician’s Guide
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
Great to see the #zoliflodacin paper.
With #gepotidacin, we have TWO new antibiotics to use for #gonorrhea! 🎉
But big Qs about use and access remain, esp in Asia Pacific, where ceftriaxone resistance is already sky high (nearly 30% in 🇻🇳)
#IDSky #STIsky #AMR
🔗: www.thelancet.com/journals/lan...
With #gepotidacin, we have TWO new antibiotics to use for #gonorrhea! 🎉
But big Qs about use and access remain, esp in Asia Pacific, where ceftriaxone resistance is already sky high (nearly 30% in 🇻🇳)
#IDSky #STIsky #AMR
🔗: www.thelancet.com/journals/lan...
December 19, 2025 at 1:09 AM
Great to see the #zoliflodacin paper.
With #gepotidacin, we have TWO new antibiotics to use for #gonorrhea! 🎉
But big Qs about use and access remain, esp in Asia Pacific, where ceftriaxone resistance is already sky high (nearly 30% in 🇻🇳)
#IDSky #STIsky #AMR
🔗: www.thelancet.com/journals/lan...
With #gepotidacin, we have TWO new antibiotics to use for #gonorrhea! 🎉
But big Qs about use and access remain, esp in Asia Pacific, where ceftriaxone resistance is already sky high (nearly 30% in 🇻🇳)
#IDSky #STIsky #AMR
🔗: www.thelancet.com/journals/lan...
Fascinating story here!
We will need to monitor these mutations as we start to use these new antibiotics, especially in the Asia Pacific region, where ceftriaxone resistance is already nearly 30% and the ParC D86N is a concern.
N. gonorrhoeae is such a humbling bug...
#Gonorrhea #AMR
We will need to monitor these mutations as we start to use these new antibiotics, especially in the Asia Pacific region, where ceftriaxone resistance is already nearly 30% and the ParC D86N is a concern.
N. gonorrhoeae is such a humbling bug...
#Gonorrhea #AMR
New preprint: with increasing resistance to ceftriaxone, the last recommended antibiotic for gonorrhea, we urgently need new drugs. Two--zoliflodacin & gepotdiacin--are up for approval by the FDA in Dec. Here we show a point mutation can result in cross-resistance. www.biorxiv.org/content/10.1...
Zoliflodacin and gepotidacin cross-resistance in Neisseria gonorrhoeae
Resistance to zoliflodacin, a first-in-class antibiotic for gonorrhea treatment, can occur through gyrBD429N, but this mutation's impact on fitness and resistance to other topoisomerase targeting drug...
www.biorxiv.org
December 19, 2025 at 12:02 AM
Fascinating story here!
We will need to monitor these mutations as we start to use these new antibiotics, especially in the Asia Pacific region, where ceftriaxone resistance is already nearly 30% and the ParC D86N is a concern.
N. gonorrhoeae is such a humbling bug...
#Gonorrhea #AMR
We will need to monitor these mutations as we start to use these new antibiotics, especially in the Asia Pacific region, where ceftriaxone resistance is already nearly 30% and the ParC D86N is a concern.
N. gonorrhoeae is such a humbling bug...
#Gonorrhea #AMR
Reposted by Paul Adamson MD MPH
🧪 #Zoliflodacin a truly new #antibiotic just for #gonorrhoea
Maybe even more important is the controversial debate about how best to use it
We work with UZH, @yhgrad.bsky.social and @gardp.bsky.social to model the best strategies in 🇿🇦
@ispm.unibe.ch @unibe.ch
www.science.org/content/arti...
Maybe even more important is the controversial debate about how best to use it
We work with UZH, @yhgrad.bsky.social and @gardp.bsky.social to model the best strategies in 🇿🇦
@ispm.unibe.ch @unibe.ch
www.science.org/content/arti...
New antibiotic for gonorrhea could help beat back drug-resistant infections
Two treatments for the sexually transmitted disease are expected to become available soon
www.science.org
December 12, 2025 at 11:34 AM
🧪 #Zoliflodacin a truly new #antibiotic just for #gonorrhoea
Maybe even more important is the controversial debate about how best to use it
We work with UZH, @yhgrad.bsky.social and @gardp.bsky.social to model the best strategies in 🇿🇦
@ispm.unibe.ch @unibe.ch
www.science.org/content/arti...
Maybe even more important is the controversial debate about how best to use it
We work with UZH, @yhgrad.bsky.social and @gardp.bsky.social to model the best strategies in 🇿🇦
@ispm.unibe.ch @unibe.ch
www.science.org/content/arti...