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Catherine Benziger MD MPH FAHA FACC

@drbenzigerheart.bsky.social

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Nov 16

Ready for an awesome day @ahascience.bsky.social #AHA24

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 31

Congratulations to the WARRIOR investigators and patients who participated! ✅High risk patients - 1 in 6 readmitted
✅Need to understand mechanisms in INOCA
✅Hard to enroll, hard to retain, underpowered neutral trial
#ACC25 @accintouch.bsky.social

Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 31

Julia Harris: Etiology of cardiac arrest in popular film and treatment is misleading and doesn't follow guidelines.
#ACC25 @accintouch.bsky.social

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Reposted by Catherine Benziger MD MPH FAHA FACC

Viet Le DMSc MPAS PA-C FACC FAHA HF-Cert @vietheartpa.bsky.social · Mar 30

Standing room only. Amazing debate on screening: CAC and separately Lpa, are we here for Universal screening?

don’t stop believing 🔥❤️❤️‍🔥
#CAC #knowlpa #knowfh #coronarydisease @accintouch.bsky.social @drbenzigerheart.bsky.social #physicianassociate #pasgobeyond #patientshealthfirst #pasdothat

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Reposted by Catherine Benziger MD MPH FAHA FACC

Eric Topol @erictopol.bsky.social · Mar 29

The use of an SGLT2 inhibitor drug improved outcomes in patients undergoing TAVI (transcatheter aortic valve implantation). A randomized, placebo-controilled trial of 620 patients with high risk
www.nejm.org/doi/full/10....
#ACC25 @nejm.org

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Reposted by Catherine Benziger MD MPH FAHA FACC

Eric Topol @erictopol.bsky.social · Mar 30

New @nejm.org #ACC25
The global impact of 5 cardiovascular risk factors (BP, cholesterol, obesity, diabetes, smoking) on life expectancy in men and women
www.nejm.org/doi/full/10.1056/NEJMoa2415879

Global Effect of Cardiovascular Risk Factors on Lifetime Estimates | NEJM

Five risk factors account for approximately 50% of the global burden of cardiovascular disease. How the presence or absence of classic risk factors affects lifetime estimates of cardiovascular dise...

www.nejm.org

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Reposted by Catherine Benziger MD MPH FAHA FACC

Dr Martha Gulati @drmarthagulati.bsky.social · Mar 30

Dr. Nissen presents #ALPACA assessing siRNA in ⬇️ Lp(a) Lepodisiran
♥️400 mg dose: 95% ⬇️, sustained 180 days but still effects after at 540 days
♥️ Large ⬇️ in Lp(a)
♥️ ApoB ⬇️ by 15%
♥️ safety favorable: 1 withdrew in placebo
#ACC25 #CVPrev
@nejm.org
📎 www.nejm.org/doi/full/10....

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 31

You have the best fellows!!

Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 30

Dr. Victor Dzau:
Future of #CVD care is going to be evolving rapidly over the next century:
❤️ Emphasis on prevention
❤️ Equitable access and affordable
❤️ Mission-based innovation
❤️ Develop national priorities

Need governance to oversee innovation, ensure ethics

#acc25
@accintouch.bsky.social

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 30

Dr. Victor Dzau:
How do we improve #cvd with rising #obesity?
✅Start with 1° and 2° #cvprev
✅Primordial prevention

@accintouch.bsky.social #acc25

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Reposted by Catherine Benziger MD MPH FAHA FACC

Dr Martha Gulati @drmarthagulati.bsky.social · Mar 29

#ACC25 #STRIDE examined Semaglutide in PAD #LBCT
👟function impairment is common in PAD with limited Tx
👟93% completed trial, 1/3 women,~ BMI 28, functionally limited (0.1/mile)
👟Sema 💉🆚UC in T2DM+symptoms PAD: walking distance ⤴️ by 13% out to 1 year🤯💥

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 30

Dr. Amy Sarma:
Who needs monogenic genetic testing for #SCAD ?
✅Men
✅Aortic aneurysm
✅Family history
✅SCAD pt wanting pregnancy

Otherwise likely polygenic
@accintouch.bsky.social #acc25
#cvprev

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 30

Hey ladies! Come to theater 1 now to hear about why we need more women leaders in clinical trials #acc25
@accintouch.bsky.social

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 30

Is menopause a disease? No! It's part of aging and occurs in 1/2 the pop.
Vasomotor symptoms are real
✅assess #cvd risk across the lifespan
✅Need outcome studies of HRT and GLP1RA by risk
✅ask♀️about all risk factors including pregnancy and cardiometabolic risks
@accintouch.bsky.social #acc25

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 30

Excited to see the results of WARRIOR study. It was a tremendous effort from so many sites (including Essentia where I was site PI) with so many women with INOCA. More to come! @accintouch.bsky.social #acc25 #cvd

AHA Science @ahascience.bsky.social · Mar 30

WARRIOR Results presented at #ACC25

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Reposted by Catherine Benziger MD MPH FAHA FACC

Dr Martha Gulati @drmarthagulati.bsky.social · Mar 30

BHF #protecttavi
#ACC25 #LBCT
❓Does routine use of Sentinel in TAVI reduce stroke

💥PROTECT TAVI demonstrates NO difference in Tx vs Control group in Stroke rate: currently would not use this in routine clinical practice
@nejm.org

www.nejm.org/doi/full/10....

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Reposted by Catherine Benziger MD MPH FAHA FACC

JACC Journals @jaccjournals.bsky.social · Mar 30

In a late-breaking clinical trial, Dr. John Forrest from @yaleschoolofmed.bsky.social reports that low-risk patients with AS treated with #TAVR had similar rates of mortality and stroke at 5 years compared to those treated with surgery jacc.org/doi/10.1016/...

#JACC #ACC25 #vhdAS #SAVR #CardioSky

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 30

Dr. Leslie Cho discusses menopause and hormone therapy and effects on #cvd #lipid
✅Statins work in women
✅Hormones work if low risk
❌ avoid in patients with #cvd, #obesity, prior #vte
@accintouch.bsky.social #acc25

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 29

Excited to be one of 71 sites in the WARRIOR study, results presented by Eileen Handberg @accintouch.bsky.social #acc25
✅ 17% event rate over 5 years
✅ No significant difference between intensive medical therapy and usually care

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 29

Great start to #acc25 with the @accintouch.bsky.social 75th anniversary gala at the Field

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 29

Come to the lp(a) debate on Sunday morning 10am S403A!

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Mar 15

This breaks my 💔
Johns Hopkins to Cut More Than 2,000 Workers Funded by Federal Aid www.nytimes.com/2025/03/13/u...

Federal Cuts Prompt Johns Hopkins to Cut More Than 2,000 Workers

The university, a leader in scientific research, has been hard hit by the Trump administration’s cuts, which will slash at least $800 million from its budget.

www.nytimes.com

Reposted by Catherine Benziger MD MPH FAHA FACC

CardioOB @cardioob.bsky.social · Nov 24

Association of Prepregnancy Cardiometabolic Health With Hypertensive Disorders of Pregnancy Among Historically Underrepresented Groups in United States

#CardioObstetrics #CardioSky #MedSky #OBGYN #JAHA
@ahajournals.bsky.social
@erinmichos.bsky.social
www.ahajournals.org/doi/10.1161/...

Association of Prepregnancy Cardiometabolic Health With Hypertensive Disorders of Pregnancy Among Historically Underrepresented Groups in the United States | Journal of the American Heart Association

www.ahajournals.org

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Reposted by Catherine Benziger MD MPH FAHA FACC

Brendon Neuen @brendonneuen.bsky.social · Nov 27

In people with T2D, effects of GLP1-RA on CV, kidney & mortality outcomes are consistent irrespective of SGLT2i

Our meta-analysis of the 3 GLP1RA diabetes clinical outcome trials with the largest prevalent use of SGLT2i in @ahajournals.bsky.social Circulation

www.ahajournals.org/doi/10.1161/...

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Reposted by Catherine Benziger MD MPH FAHA FACC

Parham Eshtehardi MD @cardioobdoc.bsky.social · Dec 8

Assessing Accuracy of CVD Prediction Using Female-Specific Risk Factors in Women Aged 45-69 Yrs in UK Biobank Study

#CardioSky #MedSky #Circulation
@ahajournals.bsky.social @ahascience.bsky.social @erinmichos.bsky.social @drmarthagulati.bsky.social
www.ahajournals.org/doi/10.1161/...

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Catherine Benziger MD MPH FAHA FACC @drbenzigerheart.bsky.social · Dec 10

Great discussion on the current state of #statin and #dementia in older adults research at the #Preventabletrial investigator meeting