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Eric Topol

@erictopol.bsky.social

140K followers 310 following 2.6K posts

physician-scientist, author, editor https://www.scripps.edu/faculty/topol/ Ground Truths https://erictopol.substack.com SUPER AGERS https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666

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Eric Jeffrey Topol is an American cardiologist, scientist, and author. He is the founder and director of the Scripps Research Translational Institute, a professor of Molecular Medicine and Executive Vice-President at Scripps Research Institute, and a senior consultant at the Division of Cardiovascular Diseases at Scripps Clinic in La Jolla, California. .. more

Medicine 88%

Public Health 4%

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Eric Topol @erictopol.bsky.social · May 27

A new cover for SUPER AGERS after making the NYT bestseller list. Thanks to you for making it the #1 ranked new non-fiction book on Amazon.
amazon.com/gp/new-relea...

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Eric Topol @erictopol.bsky.social · 5h

Reclaiming care of patients in the age of A.I.
"A.I. will not replace care, rather, it could help us rediscover it."
This week's @thelancet.com editorial
www.thelancet.com/journals/lan...

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Eric Topol @erictopol.bsky.social · 6h

Hormone replacement therapy helps restore immune function in menopausal women, reducing inflammaging and preserving monocyte function. open-access
onlinelibrary.wiley.com/doi/10.1111/...

Extends what I previously summarized from immune system clocks
erictopol.substack.com/p/new-anti-a...

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Reposted by Brendan Nyhan

Eric Topol @erictopol.bsky.social · 11h

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years?
A 30-year long mystery unraveled @ScienceMagazine today!
Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation
www.science.org/doi/10.1126/...

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Reposted by Philippe Froguel

Eric Topol @erictopol.bsky.social · 14h

Plenty of amyloid, very little tau
Low inflammatory response

nytimes.com/2025/10/07/h...

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Eric Topol @erictopol.bsky.social · 15h

Is dark chocolate good for you?
"Sadly for chocoholics, the health claims for dark chocolate come from wishful thinking and sly marketing, not the findings of science."
Sorry
www.economist.com/science-and-...

Is dark chocolate actually healthy?

We assess whether that tempting idea is too good to be true

www.economist.com

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Reposted by Michelle M. Porter

Eric Topol @erictopol.bsky.social · 1d

One thing is aging. Another is aging without the major age-related diseases. Extending healthspan. www.freethink.com/biotech/eric...

Forget just living longer. Eric Topol wants to help Americans live better, too.

In "Super Agers," the writer and medical researcher maps a path to extending healthspan with AI, targeted drugs, and lifestyle changes.

www.freethink.com

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Reposted by Eric J. Topol

Eric Topol @erictopol.bsky.social · 1d

Finding somatic mutations in healthy tissue that can lead to cancer, at scale. Yet another path to primary prevention
www.nature.com/articles/s41...
www.nature.com/articles/d41...

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Eric Topol @erictopol.bsky.social · 2d

www.washingtonpost.com/opinions/202...

Opinion | Six surgeons general: It’s our duty to warn the nation about RFK Jr.

We took an oath to declare dangers when we found them. We’re doing that again today.

www.washingtonpost.com

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Eric Topol @erictopol.bsky.social · 3d

"Anyone who is interested in the current and future states of healthspan treatments can appreciate......"—Prof @ctmurphy1.bsky.social @nature.com
www.nature.com/articles/d41...

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Eric Topol @erictopol.bsky.social · 3d

Exercising fathers, enhanced endurance and metabolic heath in offspring, through sperm microRNAs (as demonstrated in mice)
www.cell.com/cell-metabol...

Paternal exercise confers endurance capacity to offspring through sperm microRNAs

Yin et al. show that paternal exercise improves offspring endurance capacity and metabolic health via sperm microRNAs that reprogram gene expression in early embryos, revealing how exercise benefits c...

www.cell.com

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