Chris Pook
@drchrispook.bsky.social
Biochemistry, mass spectrometry, metabolomics, chromatography, health, nutrition, physiology, chemoinformatics, computational mass spec. Personal account. #SexMatters #SexNotGender https://thepoliticalerasureofsex.org/
https://projectnettie.wordpress.com/
https://projectnettie.wordpress.com/
Pinned
Chris Pook
@drchrispook.bsky.social
· Dec 18
Polar metabolomics using trichloroacetic acid extraction and porous graphitic carbon stationary phase - Metabolomics
Introduction Accurately identifying and quantifying polar metabolites using untargeted metabolomics has proven challenging in comparison to mid to non-polar metabolites. Hydrophilic interaction chroma...
link.springer.com
It's here! "Polar metabolomics using trichloroacetic acid extraction and porous graphitic carbon stationary phase". The 2nd paper from Frankie Day's PhD & 1 of only 3 in the literature applying porous graphitic carbon stationary phase for #Metabolomics.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Chris Pook
I made a map of 3.4 million Bluesky users - see if you can find yourself!
bluesky-map.theo.io
I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail
bluesky-map.theo.io
I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail
Bluesky Map
Interactive map of 3.4 million Bluesky users, visualised by their follower pattern.
bluesky-map.theo.io
February 8, 2026 at 10:59 PM
I made a map of 3.4 million Bluesky users - see if you can find yourself!
bluesky-map.theo.io
I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail
bluesky-map.theo.io
I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail
I checked the QE manual and it claims that a calibration m/z of 74 in ESI+ and 265 in ESI- makes it good enough for a range of m/z 50-2,000. I'm glad someone took the time to show that that's not right.
February 10, 2026 at 3:39 AM
I checked the QE manual and it claims that a calibration m/z of 74 in ESI+ and 265 in ESI- makes it good enough for a range of m/z 50-2,000. I'm glad someone took the time to show that that's not right.
Okay, I accept that.
February 9, 2026 at 9:21 PM
Okay, I accept that.
I don't think you're getting it. What does "interacted with" mean? Lots of scientists get approached by philanthropists and take their money. Yes, they should always check the background. It doesn't make them culpable for philanthropist's crimes if they don't. Scientists are famously introverted.
February 9, 2026 at 7:11 PM
I don't think you're getting it. What does "interacted with" mean? Lots of scientists get approached by philanthropists and take their money. Yes, they should always check the background. It doesn't make them culpable for philanthropist's crimes if they don't. Scientists are famously introverted.
Reposted by Chris Pook
Stella O'Malley in the BMJ. www.bmj.com/content/392/...
Re: Puberty blockers: Growing calls to pause controversial trial from medics, lawyers, and public
www.bmj.com
February 9, 2026 at 5:31 AM
Stella O'Malley in the BMJ. www.bmj.com/content/392/...
Actual sports scientists think this paper is garbage, bordering on overtime fraud because it is so poor.
bsky.app/profile/drch...
bsky.app/profile/drch...
Let's call this what it is: Academic fraud.
x.com/i/status/201...
x.com/i/status/201...
x.com
February 8, 2026 at 6:59 PM
Actual sports scientists think this paper is garbage, bordering on overtime fraud because it is so poor.
bsky.app/profile/drch...
bsky.app/profile/drch...
Boys actually have a physical advantage over girls from a very young age. This is partly because male infants undergo a "mini-puberty" before they're even a year old where testosterone rises.
womenssportspolicy.org/pre-puberty-...
womenssportspolicy.org/pre-puberty-...
Pre-Puberty, Children Show Marked Differences in Sport Performance - Women's Sports Policy Working Group
Before puberty boys have a competitive sports advantage over girls. Girls should not have to compete against boys regardless of gender identity
womenssportspolicy.org
February 8, 2026 at 6:57 PM
Boys actually have a physical advantage over girls from a very young age. This is partly because male infants undergo a "mini-puberty" before they're even a year old where testosterone rises.
womenssportspolicy.org/pre-puberty-...
womenssportspolicy.org/pre-puberty-...
Reposted by Chris Pook
An article in the New York Review of Books takes an extreme stand on biological sex, failing to define it and ultimately arguing that you're whatever sex you say you are.
whyevolutionistrue.com/2026/02/08/n...
whyevolutionistrue.com/2026/02/08/n...
NYRB article attacks the biological definition of sex holding with definitions based on self-identification
I used to subscribe to the New York Review of Books, which, while sometimes a repository for boring academic cat-fights, often included engaging and illuminating articles—until fabled editor Bob Si…
whyevolutionistrue.com
February 8, 2026 at 6:02 PM
An article in the New York Review of Books takes an extreme stand on biological sex, failing to define it and ultimately arguing that you're whatever sex you say you are.
whyevolutionistrue.com/2026/02/08/n...
whyevolutionistrue.com/2026/02/08/n...
Stunning day yesterday to climb Rangitoto. The dormant volcano just off the coast of Auckland.
February 8, 2026 at 9:02 AM
Stunning day yesterday to climb Rangitoto. The dormant volcano just off the coast of Auckland.
Excellent timing.
www.statnews.com/2026/02/07/h...
www.statnews.com/2026/02/07/h...
STAT readers respond on the ethics of gender-affirming care for minors, the new food pyramid, and more
Authors of HHS report criticize recent STAT op-ed on gender-affirming care for minors for using “scare tactics.”
www.statnews.com
February 8, 2026 at 7:52 AM
Excellent timing.
www.statnews.com/2026/02/07/h...
www.statnews.com/2026/02/07/h...
LOL, no. You seem to have medicine confused with fairy godmothers.
February 8, 2026 at 5:38 AM
LOL, no. You seem to have medicine confused with fairy godmothers.
Implying that anyone named is morally culpable is stupid, not to mention bordering on actionable. Disclaimer: I am not a lawyer.
February 8, 2026 at 3:43 AM
Implying that anyone named is morally culpable is stupid, not to mention bordering on actionable. Disclaimer: I am not a lawyer.
We know that Epstein was a prolific philanthropist and liked to befriend scientists. Scientists being named on the Epstein files does not equate to them being paedophiles. I know of at least one eminent scientist who is named but had only passing contact with Epstein & nothing to do with his crimes.
At least 30 scientists, including famous paleontologist Jack Horner and theoretical physicist Stephen Hawking, have been named in the Epstein files so far. Once again proving that shitty men think with the wrong head no matter how smart they are.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Epstein files reveal deeper ties to scientists than previously known
Latest batch of documents show researchers consulting the financier and sex offender on publications, visas and more.
www.nature.com
February 8, 2026 at 3:41 AM
We know that Epstein was a prolific philanthropist and liked to befriend scientists. Scientists being named on the Epstein files does not equate to them being paedophiles. I know of at least one eminent scientist who is named but had only passing contact with Epstein & nothing to do with his crimes.
Oh, Olivia. So disappointing.
February 7, 2026 at 10:02 PM
Oh, Olivia. So disappointing.
What an odd response. Do you genuinely believe it's controversial to expect medical professionals to act rationally on the basis of evidence?
February 7, 2026 at 10:00 PM
What an odd response. Do you genuinely believe it's controversial to expect medical professionals to act rationally on the basis of evidence?
Yep. This. It's such a disaster for everyone involved. And yet none of it is necessary!
February 7, 2026 at 9:58 PM
Yep. This. It's such a disaster for everyone involved. And yet none of it is necessary!
No, they're doing it to establish the integrity of the rationale medical professionals are expressing for carrying out medical interventions upon children with significant potential for serious, negative, lifelong outcomes.
February 7, 2026 at 8:43 PM
No, they're doing it to establish the integrity of the rationale medical professionals are expressing for carrying out medical interventions upon children with significant potential for serious, negative, lifelong outcomes.
Reposted by Chris Pook
I wrote about Dr. Jonathan Howard's view that to ask the question "What is a man?" is to put people in physical danger. I also questioned doctors who are unfamiliar with the bare basics of research methods can provide good care to their patients.
jessesingal.substack.com/p/how-can-do...
jessesingal.substack.com/p/how-can-do...
How Can Doctors Like This Provide Competent Care To Their Patients?
Some beef with Dr. Jonathan Howard
jessesingal.substack.com
February 7, 2026 at 7:30 PM
I wrote about Dr. Jonathan Howard's view that to ask the question "What is a man?" is to put people in physical danger. I also questioned doctors who are unfamiliar with the bare basics of research methods can provide good care to their patients.
jessesingal.substack.com/p/how-can-do...
jessesingal.substack.com/p/how-can-do...
"Stunting a child’s mental, physical, sexual and reproductive development based on an impossible dream isn’t kindness, it’s child abuse. Passing the responsibility to children to make the decision is deeply unethical."
February 7, 2026 at 8:17 PM
"Stunting a child’s mental, physical, sexual and reproductive development based on an impossible dream isn’t kindness, it’s child abuse. Passing the responsibility to children to make the decision is deeply unethical."
And this. This is absolutely key to the outcomes of this trial. It expects broad social compliance with the lie. But most people know that lying to children is wrong and won't go along with it. Where does that leave these children?
February 7, 2026 at 8:16 PM
And this. This is absolutely key to the outcomes of this trial. It expects broad social compliance with the lie. But most people know that lying to children is wrong and won't go along with it. Where does that leave these children?