Chris Pook
@drchrispook.bsky.social
Biochemistry, mass spectrometry, metabolomics, chromatography, health, nutrition, physiology, chemoinformatics, computational mass spec. Personal account. #SexMatters #SexNotGender https://thepoliticalerasureofsex.org/
https://projectnettie.wordpress.com/
https://projectnettie.wordpress.com/
Pinned
Chris Pook
@drchrispook.bsky.social
· Dec 18
Polar metabolomics using trichloroacetic acid extraction and porous graphitic carbon stationary phase - Metabolomics
Introduction Accurately identifying and quantifying polar metabolites using untargeted metabolomics has proven challenging in comparison to mid to non-polar metabolites. Hydrophilic interaction chroma...
link.springer.com
It's here! "Polar metabolomics using trichloroacetic acid extraction and porous graphitic carbon stationary phase". The 2nd paper from Frankie Day's PhD & 1 of only 3 in the literature applying porous graphitic carbon stationary phase for #Metabolomics.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Seal milk! 🤩
Seal milk oligosaccharides rival human milk complexity and exhibit functional dynamics during lactation #NatCommun #MassSpec www.nature.com/articles/s41...
Seal milk oligosaccharides rival human milk complexity and exhibit functional dynamics during lactation - Nature Communications
Jin et al. discovered Atlantic grey seal milk contains 332 complex sugars, including 166 novel structures. Seal milk rivals human milk complexity, includes giant molecules up to 28 sugar units, change...
www.nature.com
November 27, 2025 at 9:35 AM
Seal milk! 🤩
The Guardian has a bunch of reader reports on people leaving New Zealand, including this one from a scientist
in Montréal last week a colleague noted that I used to be far more positive on NZ. It's wild how rapidly our science funding has been annihilated #nzpol
www.theguardian.com/world/2025/n...
in Montréal last week a colleague noted that I used to be far more positive on NZ. It's wild how rapidly our science funding has been annihilated #nzpol
www.theguardian.com/world/2025/n...
November 27, 2025 at 9:22 AM
Bird of paradise palm flower down the street.
November 26, 2025 at 6:27 AM
Bird of paradise palm flower down the street.
Sadly this did not, in fact, turn out to be the end of a very busy day. I logged in to check on my run before I started winding down for bed and saw the peak shape had started to deteriorate. So I drove in to the med school to go and change the column. Got home at 11. 🙄
#metabolomics
#massSpec
#metabolomics
#massSpec
A cup of tea and a tour of the garden is the perfect end to a very busy day. 🌼🌺🏵️🌸
November 25, 2025 at 10:16 PM
Sadly this did not, in fact, turn out to be the end of a very busy day. I logged in to check on my run before I started winding down for bed and saw the peak shape had started to deteriorate. So I drove in to the med school to go and change the column. Got home at 11. 🙄
#metabolomics
#massSpec
#metabolomics
#massSpec
The orbital frequency of the ions in my Orbitrap has sync'd with my brain's alpha waves.
November 25, 2025 at 7:36 PM
The orbital frequency of the ions in my Orbitrap has sync'd with my brain's alpha waves.
Reposted by Chris Pook
25 November 2025
International Day for the Elimination of Violence Against Women.
International Day for the Elimination of Violence Against Women.
November 25, 2025 at 12:35 AM
25 November 2025
International Day for the Elimination of Violence Against Women.
International Day for the Elimination of Violence Against Women.
A cup of tea and a tour of the garden is the perfect end to a very busy day. 🌼🌺🏵️🌸
November 25, 2025 at 6:01 AM
A cup of tea and a tour of the garden is the perfect end to a very busy day. 🌼🌺🏵️🌸
Reposted by Chris Pook
Nathan Lents and Agustín Fuentes use the "Argument from Complexity" to claim that sex isn't binary. It's the same old tired and misguided claims that Fuentes has been making for aeons, but there is no new biology (or philosophy) here.
whyevolutionistrue.com/2025/11/24/s...
whyevolutionistrue.com/2025/11/24/s...
Surprise! Agustín Fuentes and Nathan Lents criticize the sex binary
I don’t know how many times Agustín Fuentes, an anthropology professor at Princeton, will keep repeating the same arguments about why biological sex isn’t binary (see these posts on my …
whyevolutionistrue.com
November 24, 2025 at 3:37 PM
Nathan Lents and Agustín Fuentes use the "Argument from Complexity" to claim that sex isn't binary. It's the same old tired and misguided claims that Fuentes has been making for aeons, but there is no new biology (or philosophy) here.
whyevolutionistrue.com/2025/11/24/s...
whyevolutionistrue.com/2025/11/24/s...
Mrs Pook is at the garden centre and messaged me to ask if we should add this to our collection. I'm going to go with "yes". 🌺
November 24, 2025 at 12:20 AM
Mrs Pook is at the garden centre and messaged me to ask if we should add this to our collection. I'm going to go with "yes". 🌺
I want to do some #massSpec data analysis requiring manual data extraction & compilation, which is laborious & time consuming.
I could write some code to do this which would take a lot longer but would then make all future analyses much faster.
Which do I choose?
#HackersDilemma
I could write some code to do this which would take a lot longer but would then make all future analyses much faster.
Which do I choose?
#HackersDilemma
November 23, 2025 at 10:36 PM
I want to do some #massSpec data analysis requiring manual data extraction & compilation, which is laborious & time consuming.
I could write some code to do this which would take a lot longer but would then make all future analyses much faster.
Which do I choose?
#HackersDilemma
I could write some code to do this which would take a lot longer but would then make all future analyses much faster.
Which do I choose?
#HackersDilemma
Hello spiky friend.
November 22, 2025 at 10:17 PM
Hello spiky friend.
It's that time of year when the garden's full of these little guys. 🦟🪳
November 22, 2025 at 6:20 AM
It's that time of year when the garden's full of these little guys. 🦟🪳
Saturday sun 🌺🪷🌼🏵️
November 22, 2025 at 6:16 AM
Saturday sun 🌺🪷🌼🏵️
Reposted by Chris Pook
Quick heads up - there will soon be a job posting for a Staff Scientist / Senior Staff Scientist in our lab in Copenhagen to support all our mass spec proteomics adventures!
Great colleagues, lots of cool projects… and you’ll get to work with me 😅
Please DM if you’re interested!
Great colleagues, lots of cool projects… and you’ll get to work with me 😅
Please DM if you’re interested!
November 20, 2025 at 5:09 PM
Quick heads up - there will soon be a job posting for a Staff Scientist / Senior Staff Scientist in our lab in Copenhagen to support all our mass spec proteomics adventures!
Great colleagues, lots of cool projects… and you’ll get to work with me 😅
Please DM if you’re interested!
Great colleagues, lots of cool projects… and you’ll get to work with me 😅
Please DM if you’re interested!
Reposted by Chris Pook
We are hiring for a metabolomics position here at UC Riverside! Come join the vibrant research and mass spectrometry community here!
aprecruit.ucr.edu/JPF02151
aprecruit.ucr.edu/JPF02151
Assistant Professor in Computational and/or Analytical Metabolomics
University of California, Riverside is hiring. Apply now!
aprecruit.ucr.edu
November 19, 2025 at 11:52 PM
We are hiring for a metabolomics position here at UC Riverside! Come join the vibrant research and mass spectrometry community here!
aprecruit.ucr.edu/JPF02151
aprecruit.ucr.edu/JPF02151
November 20, 2025 at 7:05 AM
Aotearoa New Zealand bans new prescriptions of puberty blockers!
"I believe young people should be supported to love themselves, not change themselves with experimental medication".
- Karen Chhour, Minister for Prevention of Family Violence & Sexual Violence
#nzpol
archive.ph/2025.11.19-0...
"I believe young people should be supported to love themselves, not change themselves with experimental medication".
- Karen Chhour, Minister for Prevention of Family Violence & Sexual Violence
#nzpol
archive.ph/2025.11.19-0...
archive.ph
November 19, 2025 at 10:01 AM
Aotearoa New Zealand bans new prescriptions of puberty blockers!
"I believe young people should be supported to love themselves, not change themselves with experimental medication".
- Karen Chhour, Minister for Prevention of Family Violence & Sexual Violence
#nzpol
archive.ph/2025.11.19-0...
"I believe young people should be supported to love themselves, not change themselves with experimental medication".
- Karen Chhour, Minister for Prevention of Family Violence & Sexual Violence
#nzpol
archive.ph/2025.11.19-0...
How can you have an "ultrashort chain"? You can't have anything beyond a short chain that can still be described as a chain. That's why we have short chain fatty acids and not ultrashort chain fatty acids. This attempt to increment jargon for impact is so toxic and unnecessary.
November 18, 2025 at 2:03 AM
How can you have an "ultrashort chain"? You can't have anything beyond a short chain that can still be described as a chain. That's why we have short chain fatty acids and not ultrashort chain fatty acids. This attempt to increment jargon for impact is so toxic and unnecessary.
Reposted by Chris Pook
This chart can, and should, get a lot of attention in the second week of #COP30 because it starkly demonstrates the inequality at the heart of the climate problem
www.ft.com/content/d0c2...
www.ft.com/content/d0c2...
November 17, 2025 at 7:31 AM
This chart can, and should, get a lot of attention in the second week of #COP30 because it starkly demonstrates the inequality at the heart of the climate problem
www.ft.com/content/d0c2...
www.ft.com/content/d0c2...
Recent developments from the garden. 🌺🌺
November 17, 2025 at 6:26 PM
Recent developments from the garden. 🌺🌺
Hello @support.bsky.team, I'm sick of losing my half-drafted tweets when I switch away from the app in Android to look up information or copy text from elsewhere to include. This seems to be inconsistent. It only happens ~1/3 of the time. Can you please investigate and fix?
November 15, 2025 at 11:48 PM
Hello @support.bsky.team, I'm sick of losing my half-drafted tweets when I switch away from the app in Android to look up information or copy text from elsewhere to include. This seems to be inconsistent. It only happens ~1/3 of the time. Can you please investigate and fix?
Reposted by Chris Pook
The women described a culture of fear where even seasoned correspondents did not dare veer from the Stonewall-mandated position on trans issues in case they were accused of “transphobia”. "… It felt like activism, not news.”
www.thetimes.com/uk/media/art...
www.thetimes.com/uk/media/art...
Emails reveal BBC women complained over trans reporting
Messages dating back five years show female staff raised concerns with bosses but felt rebuffed or ignored
www.thetimes.com
November 15, 2025 at 11:29 PM
The women described a culture of fear where even seasoned correspondents did not dare veer from the Stonewall-mandated position on trans issues in case they were accused of “transphobia”. "… It felt like activism, not news.”
www.thetimes.com/uk/media/art...
www.thetimes.com/uk/media/art...
A beautifully clear and well argued paper calls for the use of precise and consistent language when discussing sex, gender and gender identity. This issue extends far beyond the academic literature into every corner of our lives.
#SexNotGender
#SexMatters
link.springer.com/article/10.1...
#SexNotGender
#SexMatters
link.springer.com/article/10.1...
A Proposal for Terminology for Clear Communication and Avoidance of Confusion in Relation to Sex, the Social Expectations of the Sexes and Gender Identity - Archives of Sexual Behavior
Archives of Sexual Behavior -
link.springer.com
November 14, 2025 at 8:35 PM
A beautifully clear and well argued paper calls for the use of precise and consistent language when discussing sex, gender and gender identity. This issue extends far beyond the academic literature into every corner of our lives.
#SexNotGender
#SexMatters
link.springer.com/article/10.1...
#SexNotGender
#SexMatters
link.springer.com/article/10.1...
Reposted by Chris Pook
So @jamesheathers.bsky.social & I answer the burning question: does Cake cause Herpes? No, but one can torture the data to give that impression, and that's a problem. Promiscuous dichotomisation in biomedical science hugely increases spurious findings, best avoided
link.springer.com/article/10.1...
link.springer.com/article/10.1...
November 13, 2025 at 12:42 PM
So @jamesheathers.bsky.social & I answer the burning question: does Cake cause Herpes? No, but one can torture the data to give that impression, and that's a problem. Promiscuous dichotomisation in biomedical science hugely increases spurious findings, best avoided
link.springer.com/article/10.1...
link.springer.com/article/10.1...