Dylan Thompson
@drdylanthompson.bsky.social
82 followers 59 following 20 posts
Professor at the University of Bath, UK https://researchportal.bath.ac.uk/en/persons/dylan-thompson. Co-Director of the Centre for Nutrition, Exercise and Metabolism https://www.bath.ac.uk/research-centres/centre-for-nutrition-exercise-and-metabolism/
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Reposted by Dylan Thompson
j-t-gonzalez.bsky.social
🚨 3-year Post-doc opportunity at the Centre for Nutrition, Exercise and Metabolism

Opportunity to lead on an RCT involving symbiotic supplementation and ketogenic diets

www.bath.ac.uk/jobs/Vacancy...

Building in our prior work

pubmed.ncbi.nlm.nih.gov/39106867/
drdylanthompson.bsky.social
I’m looking forward to presenting some of our research on the effect of exercise on vitamin D at the Vitamin D Workshop in Montreal next week.

vitamindworkshop.org/montreal-2025
Vitamin D Workshop
NEXT VITAMIN D WORKSHOP: JUNE 24-27, 2025 MONTREAL, CANADA
vitamindworkshop.org
Reposted by Dylan Thompson
sciences.skyfleet.blue
Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial
Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial
In people with overweight or obesity, regular exercise even without weight loss or vitamin D supplementation completely prevents the usual winter decline in the vitamin D metabolite that maintains health at a cellular level, 1,25(OH) 2 D 3 , and ameliorates the decline in the vitamin D status marker 25(OH)D. Abstract Many adults become vitamin D deficient or insufficient during winter at northerly latitudes when cutaneous vitamin D synthesis does not occur. Vitamin D accumulates in adipose tissue and people with overweight or obesity are more likely to have low systemic vitamin D. This randomized controlled trial demonstrates that regular exercise completely maintains serum concentrations of the active vitamin D metabolite 1,25(OH) 2 D 3 over winter and may ameliorate the decline in 25(OH)D status in overweight men and women, even without weight loss. The binding of 1,25(OH) 2 D 3 to the vitamin D receptor mediates the crucial role for vitamin D in the healthy function of multiple organ systems and vitamin D supplementation does not impact circulating 1,25(OH) 2 D 3 . Thus, the VitaDEx study provides causal evidence that exercise plays an important role in vitamin D metabolism that is distinct from the effects of oral supplementation.
advanced.onlinelibrary.wiley.com
drdylanthompson.bsky.social
We previously speculated that exercise might mobilise vitamin D from adipose tissue. Adipose can contain enormous amounts of vitamin D. This didn’t seem to happen but, as we discuss in the paper, interpretation is complex and there is a lot to consider. onlinelibrary.wiley.com/doi/full/10....
Mobilising vitamin D from adipose tissue: The potential impact of exercise
Vitamin D is lipophilic and accumulates substantially in adipose tissue. Even without supplementation, the amount of vitamin D in the adipose of a typical adult is equivalent to several months of the....
onlinelibrary.wiley.com
drdylanthompson.bsky.social
The preservation of active vitamin D (1,25(OH)₂D₃) is particularly notable given that supplementation doesn’t seem to have such an effect. Our take home if you don’t want to read on - Exercise should be promoted alongside supplementation to help maintain vitamin D status
drdylanthompson.bsky.social
Ten days left to apply for this PhD opportunity at Bath
drdylanthompson.bsky.social
New PhD opportunity in nutrition and metabolism at @uniofbath.bsky.social - closing date 31st March. Come and join CNEM! eur01.safelinks.protection.outlook.com?url=https%3A...
Reposted by Dylan Thompson
jphysiol.bsky.social
Armin Zittermann writes this #LetterToTheEditor on the functional effect of physical exercise on calcium metabolism in relation to the work of Davies et al. (2024)

📮 Read it here: buff.ly/ECX1whu
Reposted by Dylan Thompson
jnutrphys.bsky.social
Editor-in-Chief, Professor Craig Sale, introduces the Journal of Nutritional Physiology, which explores how nutrients from food interact with the body.

Submissions to the journal are now open and APCs are waived until 2027.

🔗Watch the full video to learn more: youtu.be/xs3nsjO1pbk
drdylanthompson.bsky.social
New PhD opportunity in nutrition and metabolism at @uniofbath.bsky.social - closing date 31st March. Come and join CNEM! eur01.safelinks.protection.outlook.com?url=https%3A...
drdylanthompson.bsky.social
This is patently not true. The two robust RCTs providing causal evidence (which we refer to in this piece) were funded by the US National Institutes of Health - not industry.

The public deserves better.
drdylanthompson.bsky.social
And, they are ignoring the strongest evidence. We now even have celebrity doctors claiming that “the whole idea that you can burn more calories by doing exercise was funded, if not by Coca Cola, then by the soft drinks industry”

www.youtube.com/watch?v=j1oO...
Ultra processed foods and the third age of eating - with Chris van Tulleken
YouTube video by The Royal Institution
www.youtube.com
drdylanthompson.bsky.social
Is it the science - and the intriguing notion that physiological systems have evolved which conspire against our efforts to make changes that would be positive in modern-day environments?

Whatever the motivation - they have got carried away!
drdylanthompson.bsky.social
Is it knowing that many of the general public will enjoy articles allowing them to scoff at the futile behaviour of people who might otherwise appear virtuous (exercisers)?
drdylanthompson.bsky.social
Why do journalists find the constrained energy expenditure narrative so enthralling? Is it because it gives the impression we have all been duped?
drdylanthompson.bsky.social
This illustrates some of the bombardment. There are many more. It makes a great teaching topic - evidence, science, media - it has it all.
Reposted by Dylan Thompson
gregatki.bsky.social
This piece is based on our paper, sciencedirect.com/science/arti..., which is well worth a read to see how statistics informs physiological inferences. The study of a very important physiological hypothesis being compromised by correlating X with Y-X and getting excited about a -ve slope.
drdylanthompson.bsky.social
The constrained model is certainly interesting, but I don’t think we are ready to say that people who are really active burn the same as people who are really sedentary. Indeed, during the RAUSA experiment, the athletes burned >5,000 kcal/day - not many sedentary people will get anywhere near that!