The Journal of Physiology
@jphysiol.bsky.social
The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.
In this recent study, Raif Musa-Aziz and colleagues from uspoficial.bsky.social investigated the mechanism of CO2 and NH3 transport through human #aquaporin, providing evidence for #parallel CO2 #pathways 🔬 🔎
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 15, 2026 at 4:02 PM
In this recent study, Raif Musa-Aziz and colleagues from uspoficial.bsky.social investigated the mechanism of CO2 and NH3 transport through human #aquaporin, providing evidence for #parallel CO2 #pathways 🔬 🔎
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by D'Artagnan Greene and Yohannes Shiferaw observed that APD restitution controls #arrhythmia emergence in cardiac tissue with #RyR2 dysfunction 💻 🫀
🔗 Read their work here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read their work here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 15, 2026 at 2:02 PM
#Research by D'Artagnan Greene and Yohannes Shiferaw observed that APD restitution controls #arrhythmia emergence in cardiac tissue with #RyR2 dysfunction 💻 🫀
🔗 Read their work here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read their work here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by The Journal of Physiology
Go behind the scenes and learn how a journal operates
With @jphysiol.bsky.social’s Editorial Board Fellowship you can gain insight into the #PeerReview process under the guidance of a Senior Editor. Apply by 15 March 2026 ➡️ physoc.onlinelibrary.wiley.com/hub/journal/...
#SkillsDevelopment
With @jphysiol.bsky.social’s Editorial Board Fellowship you can gain insight into the #PeerReview process under the guidance of a Senior Editor. Apply by 15 March 2026 ➡️ physoc.onlinelibrary.wiley.com/hub/journal/...
#SkillsDevelopment
January 15, 2026 at 12:02 PM
Go behind the scenes and learn how a journal operates
With @jphysiol.bsky.social’s Editorial Board Fellowship you can gain insight into the #PeerReview process under the guidance of a Senior Editor. Apply by 15 March 2026 ➡️ physoc.onlinelibrary.wiley.com/hub/journal/...
#SkillsDevelopment
With @jphysiol.bsky.social’s Editorial Board Fellowship you can gain insight into the #PeerReview process under the guidance of a Senior Editor. Apply by 15 March 2026 ➡️ physoc.onlinelibrary.wiley.com/hub/journal/...
#SkillsDevelopment
🎓 2026 Editorial Board Fellowship🎓
APPLICATIONS NOW OPEN 📣
Our #EditorialBoardFellowship is a great opportunity for ECRs to be directly involved in the editorial process under the guidance of a Senior Editor!
⏰ Apply by 15th March 👇 physoc.onlinelibrary.wiley.com/hub/journal/...
APPLICATIONS NOW OPEN 📣
Our #EditorialBoardFellowship is a great opportunity for ECRs to be directly involved in the editorial process under the guidance of a Senior Editor!
⏰ Apply by 15th March 👇 physoc.onlinelibrary.wiley.com/hub/journal/...
January 15, 2026 at 12:01 PM
🎓 2026 Editorial Board Fellowship🎓
APPLICATIONS NOW OPEN 📣
Our #EditorialBoardFellowship is a great opportunity for ECRs to be directly involved in the editorial process under the guidance of a Senior Editor!
⏰ Apply by 15th March 👇 physoc.onlinelibrary.wiley.com/hub/journal/...
APPLICATIONS NOW OPEN 📣
Our #EditorialBoardFellowship is a great opportunity for ECRs to be directly involved in the editorial process under the guidance of a Senior Editor!
⏰ Apply by 15th March 👇 physoc.onlinelibrary.wiley.com/hub/journal/...
This #SymposiumReview by Alfredo Ornelas, Jacob A. Countess, Ji Yeon Kim & Sean P. Colgan from colorado.edu discusses modifying #microbially derived short chain fatty acids to promote health 🔬 🔃
🔗 Read it here:
physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here:
physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 14, 2026 at 4:01 PM
This #SymposiumReview by Alfredo Ornelas, Jacob A. Countess, Ji Yeon Kim & Sean P. Colgan from colorado.edu discusses modifying #microbially derived short chain fatty acids to promote health 🔬 🔃
🔗 Read it here:
physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here:
physoc.onlinelibrary.wiley.com/doi/10.1113/...
David Wolf et al. observed that deletion of NPAS4 in #olfactory bulb principal #neurons alters E/I balance and impairs decoding of chemically similar odour molecules 🧠 🔬
📜 Read the study here:
physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here:
physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 14, 2026 at 2:01 PM
David Wolf et al. observed that deletion of NPAS4 in #olfactory bulb principal #neurons alters E/I balance and impairs decoding of chemically similar odour molecules 🧠 🔬
📜 Read the study here:
physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here:
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by The Journal of Physiology
'To the future, and beyond' - The Journal of Physiology's Editor-in-Chief Kim Barrett writes about the exciting future of the Journal of Physiology as it moves to a new era of Online Only.
🔗 Read it here: https://ow.ly/3ewS50XU9ys
🔗 Read it here: https://ow.ly/3ewS50XU9ys
January 13, 2026 at 12:50 PM
'To the future, and beyond' - The Journal of Physiology's Editor-in-Chief Kim Barrett writes about the exciting future of the Journal of Physiology as it moves to a new era of Online Only.
🔗 Read it here: https://ow.ly/3ewS50XU9ys
🔗 Read it here: https://ow.ly/3ewS50XU9ys
Marcos P. Rocha & Igor A. Fernandes discuss #platelets as the environmental messengers of the #neurotrophic pathway to brain plasticity and the work of Thomas et al. (2025) ✍️ 💭
🔗 Access the #Perspective: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access the #Perspective: physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 14, 2026 at 12:01 PM
Marcos P. Rocha & Igor A. Fernandes discuss #platelets as the environmental messengers of the #neurotrophic pathway to brain plasticity and the work of Thomas et al. (2025) ✍️ 💭
🔗 Access the #Perspective: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access the #Perspective: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Edoardo Lecce and colleagues present this #TopicalReview examining resistance training-induced adaptations in the #neuromuscular system, focusing on physiological mechanisms and implications for human performance 🔎 🏃
📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 13, 2026 at 5:03 PM
Edoardo Lecce and colleagues present this #TopicalReview examining resistance training-induced adaptations in the #neuromuscular system, focusing on physiological mechanisms and implications for human performance 🔎 🏃
📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Aguan D. Wei and colleagues from @seattlechildrens.org found that #fentanyl blockade of K+ channels contributes to wooden chest syndrome 🫁 💊
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 13, 2026 at 3:02 PM
Aguan D. Wei and colleagues from @seattlechildrens.org found that #fentanyl blockade of K+ channels contributes to wooden chest syndrome 🫁 💊
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this recent study, Stephen T. Barimah et al. observed that chronic #hypoxia impairs L-type Ca2+ channel-mediated myogenic #vasoconstriction and cerebral autoregulation in newborn lambs 🫀 🧠
🔗 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 13, 2026 at 12:01 PM
In this recent study, Stephen T. Barimah et al. observed that chronic #hypoxia impairs L-type Ca2+ channel-mediated myogenic #vasoconstriction and cerebral autoregulation in newborn lambs 🫀 🧠
🔗 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Gaspard Montandon from unityhealthto.bsky.social offers this #Perspective into how ether-à-go-go potassium channels freeze your breath based on the work of Wei et al. (2025) 💭 ✍️
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 12, 2026 at 4:00 PM
Gaspard Montandon from unityhealthto.bsky.social offers this #Perspective into how ether-à-go-go potassium channels freeze your breath based on the work of Wei et al. (2025) 💭 ✍️
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🎓 EDITOR'S CHOICE 🎓
Alessio Daniele and colleagues uncovered #endothelial dysfunction in both fit and untrained males assigned to sit for only 2 hours, which was ablated by preadministration of cocoa containing the #flavanol, (-)-epicatechin🪑 ⏰
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Alessio Daniele and colleagues uncovered #endothelial dysfunction in both fit and untrained males assigned to sit for only 2 hours, which was ablated by preadministration of cocoa containing the #flavanol, (-)-epicatechin🪑 ⏰
physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 12, 2026 at 12:01 PM
🎓 EDITOR'S CHOICE 🎓
Alessio Daniele and colleagues uncovered #endothelial dysfunction in both fit and untrained males assigned to sit for only 2 hours, which was ablated by preadministration of cocoa containing the #flavanol, (-)-epicatechin🪑 ⏰
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Alessio Daniele and colleagues uncovered #endothelial dysfunction in both fit and untrained males assigned to sit for only 2 hours, which was ablated by preadministration of cocoa containing the #flavanol, (-)-epicatechin🪑 ⏰
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Stephen Schlecht, Benjamin Loflin, Adam Carter, Roufael Hanna, Simran Shergill (Indiana University) and Edward M. Wojtys (@umich.edu) examine the sex differences in the #physiological response to acute anterior cruciate #ligament overuse.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 11, 2026 at 1:59 PM
Stephen Schlecht, Benjamin Loflin, Adam Carter, Roufael Hanna, Simran Shergill (Indiana University) and Edward M. Wojtys (@umich.edu) examine the sex differences in the #physiological response to acute anterior cruciate #ligament overuse.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
This paper from Louise Bradshaw (@uniofbath.bsky.social) et al. assessed the independent effects of #carbohydrate and fatty acid availability on exercise-induced skeletal #muscle AMPK activation and downstream #signalling.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 10, 2026 at 2:14 PM
This paper from Louise Bradshaw (@uniofbath.bsky.social) et al. assessed the independent effects of #carbohydrate and fatty acid availability on exercise-induced skeletal #muscle AMPK activation and downstream #signalling.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
Check out this #JournalClub article from Jeff Jiefu Liu and Ryan Yunzhen Shen (@science.ubc.ca), as they provide further insights on exercise-induced arterial hypoxaemia and patients with heart failure, adding to the work of Leahy et al. (603.22).
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 10, 2026 at 12:00 PM
Check out this #JournalClub article from Jeff Jiefu Liu and Ryan Yunzhen Shen (@science.ubc.ca), as they provide further insights on exercise-induced arterial hypoxaemia and patients with heart failure, adding to the work of Leahy et al. (603.22).
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
Alireza Poshtkohi (@herts.ac.uk) and Brian D. Gulbransen (@michiganstateu.bsky.social) show off their generalised Hodgkin–Huxley model that provide quantitative insights into how P2XRs and AMPA receptors control ion channel function.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 9, 2026 at 4:49 PM
Alireza Poshtkohi (@herts.ac.uk) and Brian D. Gulbransen (@michiganstateu.bsky.social) show off their generalised Hodgkin–Huxley model that provide quantitative insights into how P2XRs and AMPA receptors control ion channel function.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this new #PhysiologyShort, Josca M. Schoonejans of cam.ac.uk & imperialcollegeldn.bsky.social explains her recent work into #cardiovascular outcome in offspring of #metformin-treated obese mice 🫀 🔬
📽️⬇️
www.youtube.com/watch?v=H2aB...
📜⬇️
physoc.onlinelibrary.wiley.com/doi/10.1113/...
📽️⬇️
www.youtube.com/watch?v=H2aB...
📜⬇️
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Exploring the cardiovascular outcome in the offspring of metformin-treated obese mice
In this Physiology Shorts video, hear from Research Fellow at Imperial College London, Josca Schoonejans, as she takes us behind her paper titled, 'Cardiovascular outcome in 12-month-old male and…
www.youtube.com
January 9, 2026 at 3:51 PM
In this new #PhysiologyShort, Josca M. Schoonejans of cam.ac.uk & imperialcollegeldn.bsky.social explains her recent work into #cardiovascular outcome in offspring of #metformin-treated obese mice 🫀 🔬
📽️⬇️
www.youtube.com/watch?v=H2aB...
📜⬇️
physoc.onlinelibrary.wiley.com/doi/10.1113/...
📽️⬇️
www.youtube.com/watch?v=H2aB...
📜⬇️
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by The Journal of Physiology
Excited to see our study on antenatal #melatonin for #cardiovascular deficits in FGR highlighted by @jphysiol.bsky.social 🫀💊
The findings paint a nuanced picture, melatonin may offer protection, but it’s not uniform, highlighting the importance of understanding therapies fully in large animal models
The findings paint a nuanced picture, melatonin may offer protection, but it’s not uniform, highlighting the importance of understanding therapies fully in large animal models
Recent #Research by Charmaine R. Rock of monashuniversity.bsky.social et al. examines antenatal #melatonin for #cardiovascular deficits in fetal growth restriction 🫀 💊
🔗 📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 8, 2026 at 11:47 PM
Excited to see our study on antenatal #melatonin for #cardiovascular deficits in FGR highlighted by @jphysiol.bsky.social 🫀💊
The findings paint a nuanced picture, melatonin may offer protection, but it’s not uniform, highlighting the importance of understanding therapies fully in large animal models
The findings paint a nuanced picture, melatonin may offer protection, but it’s not uniform, highlighting the importance of understanding therapies fully in large animal models
Our first issue of 2026 is now live!
Featuring cover art from David Wolf and colleagues' work into olfactory bulb principal neurons🧠🔎
🔗 📖 Access the full issue here:
physoc.onlinelibrary.wiley.com/toc/14697793...
Featuring cover art from David Wolf and colleagues' work into olfactory bulb principal neurons🧠🔎
🔗 📖 Access the full issue here:
physoc.onlinelibrary.wiley.com/toc/14697793...
January 9, 2026 at 11:02 AM
Our first issue of 2026 is now live!
Featuring cover art from David Wolf and colleagues' work into olfactory bulb principal neurons🧠🔎
🔗 📖 Access the full issue here:
physoc.onlinelibrary.wiley.com/toc/14697793...
Featuring cover art from David Wolf and colleagues' work into olfactory bulb principal neurons🧠🔎
🔗 📖 Access the full issue here:
physoc.onlinelibrary.wiley.com/toc/14697793...
Ronan Berg (Rigshospitalet) gives a historical account of skeletal muscle as an endocrine organ in this #TopicalReview.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 8, 2026 at 4:04 PM
Ronan Berg (Rigshospitalet) gives a historical account of skeletal muscle as an endocrine organ in this #TopicalReview.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
"To the future, and beyond". Check out this #Editorial from our Editor-in-Chief, Kim Barrett of @ucdavis.bsky.social!
🎓 physoc.onlinelibrary.wiley.com/doi/10.1113/...
🎓 physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 8, 2026 at 2:04 PM
"To the future, and beyond". Check out this #Editorial from our Editor-in-Chief, Kim Barrett of @ucdavis.bsky.social!
🎓 physoc.onlinelibrary.wiley.com/doi/10.1113/...
🎓 physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by The Journal of Physiology
A new internationally author group with a deeply relevant publication highlighting key issues and challenges in precision medicine: jprecisionmedicine.org/article/S305... @jprecmed.bsky.social @jphysiol.bsky.social @physoc.bsky.social
January 3, 2026 at 2:50 AM
A new internationally author group with a deeply relevant publication highlighting key issues and challenges in precision medicine: jprecisionmedicine.org/article/S305... @jprecmed.bsky.social @jphysiol.bsky.social @physoc.bsky.social
Kelly H. Lee and Neil S. Magoski (Queen’s University) demonstrate how an agonist-induced depression of the cholinergic current in Aplysia bag cell neurons requires ionotropic acetylcholine receptor trafficking.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 7, 2026 at 4:22 PM
Kelly H. Lee and Neil S. Magoski (Queen’s University) demonstrate how an agonist-induced depression of the cholinergic current in Aplysia bag cell neurons requires ionotropic acetylcholine receptor trafficking.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
This #Review from Horeau, Auffret, Loréal and Derbré ( University of Rennes) provides a summary of invetigations in extreme physical inactivity, altered systemic and cellular iron homeostasis, as they explore the underlying mechanisms.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
January 7, 2026 at 2:47 PM
This #Review from Horeau, Auffret, Loréal and Derbré ( University of Rennes) provides a summary of invetigations in extreme physical inactivity, altered systemic and cellular iron homeostasis, as they explore the underlying mechanisms.
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...