Gargi Banerjee
drgargibanerjee.bsky.social
Gargi Banerjee
@drgargibanerjee.bsky.social
Alzheimer's Research UK, Stroke Association & NIHR Clinical Lecturer at UCL, interested in cerebral amyloid angiopathy (CAA) causes & consequences.
New in JNNP - the next chapter in the story of iatrogenic CAA 📕 and it really does seem to be different to sporadic CAA. Presence of deep haemorrhagic pathology in particular is unexpected but persistent signal.

So what does this mean? … 1/2🧵

jnnp.bmj.com/content/earl...
Clinical-radiological presentation and natural history of iatrogenic cerebral amyloid angiopathy
Background We aimed to describe neuroimaging features, clinical profiles and long-term outcomes in patients with iatrogenic cerebral amyloid angiopathy (iCAA). Methods We performed a systematic liter...
jnnp.bmj.com
March 1, 2025 at 12:03 PM
It’s certainly the most comprehensive meta-analysis I’ve ever been involved with 🤓

TLDR: non-motor symptoms after stroke are common across domains and guess what? Not a great deal has changed in the last decade. A real wake up call to the field to address this huge unmet need

ja.ma/3EMdegV
Patient-Reported Nonmotor Outcomes After Stroke
This systematic review and meta-analysis evaluates the prevalence, natural history, and factors associated with multidomain nonmotor outcome burden in patients with stroke.
jamanetwork.com
February 22, 2025 at 6:49 AM
We tend to think of CAA-related inflammation as its own separate thing - but is this right?

@AminaSellimi @UCLStrokeRes et al have found inflammation in people with prolonged TFNE (amyloid spells) - even though they all had "non-inflammatory" CAA... 1/2

onlinelibrary.wiley.com/doi/10.1002/...
Inflammation in Cerebral Amyloid Angiopathy‐Related Transient Focal Neurological Episodes
Transient focal neurological episodes (TFNE), often associated with convexity subarachnoid hemorrhage (cSAH), are common in cerebral amyloid angiopathy (CAA), but their pathophysiology remains incomp....
onlinelibrary.wiley.com
January 10, 2025 at 8:16 PM
Misty walk earlier today
December 26, 2024 at 6:59 PM
We define CAA-ri by classical (asymmetrical, waxing/waning) white matter changes - this paper, new from the UCL Stroke Research Centre, describes imaging features of inflammation in CAA-ri that appear *before* these white matter changes ...1/2

www.neurology.org/doi/10.1212/...
Sulcal Hyperintensity as an Early Imaging Finding in Cerebral Amyloid Angiopathy–Related Inflammation | Neurology
Background and ObjectivesCerebral amyloid angiopathy–related inflammation (CAA-ri) is a subtype of CAA with distinct clinical and radiologic features. Existing diagnostic criteria require the presence...
www.neurology.org
December 13, 2024 at 9:58 AM
Stretching my legs after an intense morning of writing
November 21, 2024 at 1:45 PM