Well this might help differentiate between iatrogenic and sporadic CAA - especially important in older people - and then why deep pathology? Subtle inflammation? Do we need a closer look at sporadic CAA?

V grateful to patients who share their stories, making these steps forward possible 🙏🏽 … 2/2 🧵

So is it inflammation rather than acute cSAH that drives TFNE?🐔vs🥚but anatomical localisation of inflammation with symptoms is v. interesting... and then should we be treating TFNE with steroids?? 🤔

Seems there's more inflammation in regular CAA than we ever suspected... 2/2

Why is this important and/or relevant?

(1) Not all patients with CAA-ri have classical white matter changes, so these features could support diagnosis;

(2) This could help CAA-ri be diagnosed (and treated) earlier, winding back the clock for defining "early" CAA-ri ⏰

…2/2