Xiao Huang
@drxiaohuang.bsky.social
Postdoc, Rudensky lab @mskcancercenter.bsky.social @ludwigcancer.bsky.social at Sloan Kettering | Postdoctoral Fellow, Cancer Research Institute | Former PhD trainee in the Murphy lab at WashU DBBS
Reposted by Xiao Huang
(1/2) Researchers from the Sloan Kettering Institute at MSK discovered that not all regulatory T cells behave the same way in tumors. Some help fight cancer, while others protect it.
December 15, 2025 at 8:14 PM
(1/2) Researchers from the Sloan Kettering Institute at MSK discovered that not all regulatory T cells behave the same way in tumors. Some help fight cancer, while others protect it.
Excited to share our new study, the paper is out today @cp-immunity.bsky.social! Not all Treg cells are the same. We identified two Treg cell subsets with opposing functions in colorectal cancer (CRC). 1/8
Online now: Opposing functions of distinct regulatory T cell subsets in colorectal cancer
Opposing functions of distinct regulatory T cell subsets in colorectal cancer
Huang et al. study the heterogeneity of regulatory T (Treg) cells in a genetic model of colorectal cancer (CRC) and find that interleukin (IL)-10− Treg cells promote tumor progression, whereas IL-10+ Treg cells restrain tumor growth by suppressing IL-17 production from CD4+ T cells. This functional dichotomy between Treg subsets is seen in human CRC and may be relevant in other barrier tissue cancers.
dlvr.it
December 15, 2025 at 9:34 PM
Excited to share our new study, the paper is out today @cp-immunity.bsky.social! Not all Treg cells are the same. We identified two Treg cell subsets with opposing functions in colorectal cancer (CRC). 1/8
Reposted by Xiao Huang
Meet #MSKPostdoc Xiao Huang (@drxiaohuang.bsky.social) from the Rudensky Lab! Xiao investigates how different subsets of regulatory T (Treg) cells adapt to tissues and immune challenges to maintain immune balance in health and disease. #NPAW2025 🇨🇳
September 30, 2025 at 6:32 PM
Meet #MSKPostdoc Xiao Huang (@drxiaohuang.bsky.social) from the Rudensky Lab! Xiao investigates how different subsets of regulatory T (Treg) cells adapt to tissues and immune challenges to maintain immune balance in health and disease. #NPAW2025 🇨🇳
Reposted by Xiao Huang
After many years of work I’m so happy to share our work on #scienceimmunology on how Treg cells modulate nociception to dampen skin inflammation! My handle will make a lot more sense now!🕵🏻♀️
Enkephalin-producing regulatory T cells in the skin restrain local inflammation through control of nociception
Regulatory T cells curb noxious sensory signaling to dampen cutaneous inflammation, a neuromodulatory mechanism for immunosuppression.
www.science.org
September 5, 2025 at 6:53 PM
After many years of work I’m so happy to share our work on #scienceimmunology on how Treg cells modulate nociception to dampen skin inflammation! My handle will make a lot more sense now!🕵🏻♀️