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Reposted by Emilie Reas

Randy McIntosh @ar0mcintosh.bsky.social · 15d

Wow! This is amazing news. Having friends who are confronted with Huntington's, this brings a ray of hope.

bbc.com/news/article...

Huntington's disease successfully treated for first time

One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

bbc.com

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Nature @nature.com · Aug 10

Replenishing the brain’s natural stores of lithium can protect against and even reverse Alzheimer’s disease

go.nature.com/4m8zW3H

New hope for Alzheimer’s: lithium supplement reverses memory loss in mice

Nature - Studies in rodents and humans suggest that low levels of the metal contribute to cognitive decline.

go.nature.com

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Matthew Panizzon @matthewpanizzon.bsky.social · Aug 8

New paper out from the lab, demonstrating a robust non-linear relationship between age at menopause and dementia risk. Fantastic work by post-doc Dr. Ursula Saelzler. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Age of menopause and dementia risk in 10,832 women from the Swedish Twin Registry

INTRODUCTION An earlier age of menopause (AOM) is hypothesized to increase vulnerability to the neuropathological processes of dementia, which begin in midlife. METHODS We tested this hypothesis i.....

alz-journals.onlinelibrary.wiley.com

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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · Jul 14

"Nature has learnt that, as a result, some staff members are screening candidates’ social-media presences to check whether they have expressed negative views about the Trump administration or been involved in diversity, equity and inclusion (DEI) efforts...at their institutions." 🧪

Max Kozlov @maxkozlov.bsky.social · Jul 14

NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding.

NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.

Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities

The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.

www.nature.com

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Max Kozlov @maxkozlov.bsky.social · Jul 2

The full ruling explaining why NIH grant cuts are illegal came out today.

It's just as blistering as the judge's oral remarks. And it uncovers fresh details in DOGE's role orchestrating the cuts — and on the cuts at Columbia.

Here are my top highlights from the 103-page ruling. 🧵

Max Kozlov @maxkozlov.bsky.social · Jun 17

After ruling the NIH grant cuts were illegal yesterday, Judge Young, a Reagan appointee on the bench since 1985, ended the hearing with a blistering 15-minute speech.

I've cleaned up my notes — here are his remarks in full. 🧵

Judge rules against NIH grant cuts — and calls them discriminatory

The decision means that the US biomedical agency has to restore funding to hundreds of research projects, but the government will likely appeal.

www.nature.com

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Rebecca Pompano @pompanolab.bsky.social · Jun 29

It seems that only the science community is noticing that NIH and NSF budgets are cut 40% and 55% in the budget bill, respectively. If you live in Maine, West Va, Pennsylvania, Alabama, or Louisiana, CALL YOUR SENATOR as they could make a difference. See below.

prospect.org/politics/202...

Will the Senate Save NIH?

Rescuing biomedical research is every bit as important as saving Medicaid.

prospect.org

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Dr.Dr. Helene Andrews-Polymenis @hpolymenis.bsky.social · Jun 18

I applied for this trial. This could EASILY have been me. Or someone else you know.

Jeremy Berg @jeremymberg.bsky.social · Jun 18

Powerful story from Carolyn Johnson at the Washington Post...

wapo.st/44ntbo4

[Should be a gift link; let me know if there are problems]

His custom cancer therapy is in an NIH freezer. He may not get it in time.

The purge of probationary federal workers included skilled lab personnel who would have finalized a customized cell immunotherapy for cancer patients.

wapo.st

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Emilie Reas @etreas.bsky.social · Jun 19

My mom also applied for one of Dr Rosenberg's trials for pancreatic cancer. Meeting eligibility criteria is enough of a hurdle; just devastating the administration is blocking access to possibly life-saving therapy.
PS, congrats on your 5.5 years!!! You're an inspiration.

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Emilie Reas @etreas.bsky.social · Jun 17

Judge Young: “This represents racial discrimination and discrimination against America’s LGBTQ community. I would be blind not to call it out ...I’ve been on the bench for 40 years — I’ve never seen government racial discrimination like this.”

Nature @nature.com · Jun 16

A US judge has ordered hundreds of terminated research projects at the US National Institutes of Health to be reinstated, calling the processes that led to their cancellation “bereft of reasoning”.

https://go.nature.com/4kOmXDy

Judge rules against NIH grant cuts — and calls them discriminatory

The decision means that the US biomedical agency has to restore funding to hundreds of research projects, but the government will likely appeal.

go.nature.com

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Dr. Lucky Tran @luckytran.com · Jun 15

Incredible turn out for #NoKingsDay. Thank you to everyone speaking up and taking action. Dissent is patriotic!

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Megan Ranney MD MPH @meganranney.bsky.social · Jun 15

Over the next 25 years, if proposed cuts in NIH funding are made real, “In a population of more than 340 million, this reflects **82 million** fewer years of life.”

In the US alone.

jamanetwork.com/journals/jam...

Cutting the NIH—The $8 Trillion Health Care Catastrophe

This JAMA Forum discusses the recent budget cuts to National Institutes of Health (NIH), the effects of these cuts on scientific research and health of individuals in the US, and the prospects for cha...

jamanetwork.com

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ProPublica @propublica.org · Jun 14

We heard directly from more than 150 researchers, scientists and investigators about their terminated NIH grants and the science that’s being lost. Full story ⤵️

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Imaging Neuroscience @imagingneurosci.bsky.social · Jun 3

New paper in Imaging Neuroscience by Emilie T. Reas, Jennifer S. Graves, et al:

Long COVID-related blood-brain barrier breakdown and microstructure in older adults are modified by sex and Alzheimer’s disease genetic risk

doi.org/10.1162/IMAG...

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Jeff Leek @jtleek.bsky.social · Jun 4

These are not just grants. This is thousands of people who devoted their lives and careers - taking pay cuts, working long hours, living with uncertainty - all for the chance to try to make people's lives a bit better for you and your loved ones. This breaks my heart.

Joshua Tucker @jatucker.bsky.social · Jun 4

Cutting NIH or NSF funding sounds abstract. Seeing what research is actually being cut makes it real. Kudos to @nytimes.com for this piece:

www.nytimes.com/interactive/...

Here Are the Nearly 2,500 Medical Research Grants Canceled or Delayed by Trump

Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.

www.nytimes.com

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Stanford AAUP @stanfordaaup.bsky.social · Jun 1

Two VA pulmonologists rebuked by Trump administration for warning, in a @nejm.org article, that cancelled contracts, layoffs, and planned staff reductions jeopardize the health of a million veterans seeking help for conditions linked to toxic exposure.

www.theguardian.com/us-news/2025...

Exclusive: US veterans agency orders scientists not to publish in journals without clearance

Move that seeks political control of doctors’ and scientists’ published research fits a pattern of censorship by the Trump administration, veterans advocates say

www.theguardian.com

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Emilie Reas @etreas.bsky.social · Jun 2

She also examined whether method of operationalizing BBB permeability matters, and compared a continuous measure vs an "abnormal leakage index (ALI)" of above-threshold values. Results were comparable across methods, supporting the robustness of findings, though ALI threshold influences effect size.

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Emilie Reas @etreas.bsky.social · Jun 2

New work from our postdoc Seraphina Solders shows patterns of blood-brain barrier leakage in cognitively normal APOE4 carriers. BBB breakdown correlated with microstructural brain injury only in groups with high Alzheimer's disease risk (APOE4+, amyloid+, women) www.sciencedirect.com/science/arti...

Blood-brain barrier permeability varies by brain region and APOE4 status and correlates with brain microstructure among high-AD risk groups

Although strong evidence exists for blood–brain barrier (BBB) disruption in Alzheimer’s disease (AD), substantial uncertainty remains regarding its ro…

www.sciencedirect.com

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Mexico News @mexiconews.bsky.social · May 31

Battle between Honest People of the US Vs. Coward ICE criminals

San Diego CA

x.com/BTnewsroom/s...

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American Federation for Aging Research (AFAR) @afar.org · May 29

Our annual grantee conference convenes past and current grantees to share insights.
Among today’s presenters:
2021 BIG Award recipients Bradley Olwin, PhD, and Andrey Tsvetkov, PhD.
2022 McKnight Grantees @etreas.bsky.social, and Tara Tracy, PhD.
Check out tomorrow's schedule: ow.ly/KVLf50VZjZq

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anil oza @aniloza.bsky.social · May 27

@scott-delaney.bsky.social has had a front row seat to the Trump admin’s cancellation of NIH grants

I caught up with Scott as his project to track research grant terminations became real personal — and his own funds were cut 🧪

www.statnews.com/2025/05/27/n...

A Harvard scientist built a database of 2,100 NIH grant terminations. Then his own funding was cut

Harvard's Scott Delaney helped build a database of NIH grant terminations that is being used in litigation against the Trump administration.

www.statnews.com

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Maria Carrillo @mariacarrilloalz.bsky.social · May 16

The myths and fabrications persistently shared by the Health and Human Services Secretary aren’t just disappointing – they’re dangerous. See below for the facts and for our full statement in response to the Secretary’s comments.

Alzheimer's Association @alzassociation.bsky.social · May 15

❌ FALSE: “For 20 years…we were directing Alzheimer’s research to one hypothesis. And any other hypotheses were shut down.” - Sec. Kennedy

Over the last decade, less than 14% of new National Institutes of Health (NIH) Alzheimer’s projects focused on amyloid beta as the therapeutic target. 🧵(1/4)

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Alzheimer's Association @alzassociation.bsky.social · May 15

Read our full statement calling on Sec. Kennedy to stop spreading harmful Alzheimer’s myths: bit.ly/43dRIKw. 4/4

Contrary to Clear, Verifiable Facts, Secretary Kennedy Continues to Repeat Harmful Myths About Alzheimer’s and Dementia Research

The Alzheimer's Association calls on HHS Secretary Kennedy to stop dangerous fabrications about the state of Alzheimer’s and dementia research.

bit.ly

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Eric Reinhart @eric-reinhart.com · May 2

Since this was published yesterday, NPR reports JAMA joins NEJM on the list of journals that confirms they’ve been sent threatening letters by Trump’s DOJ, ominously referencing their tax-exempt status in a bid to compel regime-friendly editorial choices.
www.scientificamerican.com/article/the-...

The Scary Implications of U.S. Government Attacks on Medical Journals

A Trump-aligned prosecutor’s attack on medical journals is a threat to your health care—and the medical establishment should not comply

www.scientificamerican.com

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Jeremy Berg @jeremymberg.bsky.social · Apr 30

Science article with perspectives from NIH insiders

www.science.org/content/arti...

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NIH insiders: Trump is ‘dismantling and destroying everything’

After just 100 days, agency scientists say U.S. health institutes are demoralized and have lost essential staff and funding

www.science.org

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Emilie Reas @etreas.bsky.social · Apr 23

Why do women experience Alzheimer's disease at twice the rate of men? It might be genetic, hormonal, social, cultural, or most likely multifactorial. This is just one of many questions that urgently demands ongoing support for biomedical research on sex/gender health. www.nature.com/articles/d41...

Why women experience Alzheimer’s disease differently from men

Sex and gender research could lead to better, more equitable treatments — if it is allowed to continue without political interference.

www.nature.com

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