Freddy Boutrot
@freddyboutrot.bsky.social
Translational researcher in plant disease resistance
@Limagrain, opinions are my own 🌽🌾🧬🔬
@Limagrain, opinions are my own 🌽🌾🧬🔬
Reposted by Freddy Boutrot
I just published: On the diversity of resting states of NLR immune receptors
New story on rice Pik NLR immune receptor pair — turns out it sits as a 1 MDa membrane-bound beast before activation 🤯. Another wild twist in the ever-expanding universe of NLR resting states!
medium.com/p/on-the-div...
New story on rice Pik NLR immune receptor pair — turns out it sits as a 1 MDa membrane-bound beast before activation 🤯. Another wild twist in the ever-expanding universe of NLR resting states!
medium.com/p/on-the-div...
On the diversity of resting states of NLR immune receptors
New story on the rice Pik NLR immune receptor pair — turns out it sits as a 1 MDa membrane-bound beast before activation 🤯. Another wild…
medium.com
December 4, 2025 at 11:51 AM
I just published: On the diversity of resting states of NLR immune receptors
New story on rice Pik NLR immune receptor pair — turns out it sits as a 1 MDa membrane-bound beast before activation 🤯. Another wild twist in the ever-expanding universe of NLR resting states!
medium.com/p/on-the-div...
New story on rice Pik NLR immune receptor pair — turns out it sits as a 1 MDa membrane-bound beast before activation 🤯. Another wild twist in the ever-expanding universe of NLR resting states!
medium.com/p/on-the-div...
LRR-RLK subfamily II of coreceptors: emerging, non-canonical and canonical roles in plant antiviral immunity and development doi.org/10.3389/fpls...
Frontiers | LRR-RLK subfamily II of coreceptors: emerging, non-canonical and canonical roles in plant antiviral immunity and development
Coreceptors act together with receptors in the process of signal transduction. Within the LRR-RLK subfamily II, coreceptors play an essential role by serving...
doi.org
December 4, 2025 at 11:47 AM
LRR-RLK subfamily II of coreceptors: emerging, non-canonical and canonical roles in plant antiviral immunity and development doi.org/10.3389/fpls...
Reposted by Freddy Boutrot
Reposted by Freddy Boutrot
Excited to share our latest work on plant immune receptor biochemistry! @kamounlab.bsky.social @hsuanpai.bsky.social @mpcontreras.bsky.social Jose Salguero Linares @danielluedke.bsky.social @adnroide.bsky.social @jiorgoskourelis.bsky.social
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
December 3, 2025 at 9:20 AM
Excited to share our latest work on plant immune receptor biochemistry! @kamounlab.bsky.social @hsuanpai.bsky.social @mpcontreras.bsky.social Jose Salguero Linares @danielluedke.bsky.social @adnroide.bsky.social @jiorgoskourelis.bsky.social
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Freddy Boutrot
Our paper on Zymoseptoria tritici 3D genome organization is officially out! @iglavincheska.bsky.social
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Three-dimensional genome architecture connects chromatin structure and function in a major wheat pathogen - BMC Biology
Background Genome spatial organization plays a fundamental role in biological function across all domains of life. While the principles of nuclear architecture have been well-characterized in animals ...
link.springer.com
November 28, 2025 at 12:43 PM
Our paper on Zymoseptoria tritici 3D genome organization is officially out! @iglavincheska.bsky.social
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Freddy Boutrot
"Leaf It to Science: Uncovering Plant Immune Systems Through Technological Advances Open Access"
Reflections on Career, #PlantScience and #PlantImmunity by Xinnian Dong
academic.oup.com/plphys/advan...
Reflections on Career, #PlantScience and #PlantImmunity by Xinnian Dong
academic.oup.com/plphys/advan...
November 29, 2025 at 7:01 PM
"Leaf It to Science: Uncovering Plant Immune Systems Through Technological Advances Open Access"
Reflections on Career, #PlantScience and #PlantImmunity by Xinnian Dong
academic.oup.com/plphys/advan...
Reflections on Career, #PlantScience and #PlantImmunity by Xinnian Dong
academic.oup.com/plphys/advan...
Reposted by Freddy Boutrot
Plant-derived peptides: from identification to agronomic applications #perspective #MolecularPlant cell.com/molecular-pl...
November 20, 2025 at 6:02 AM
Plant-derived peptides: from identification to agronomic applications #perspective #MolecularPlant cell.com/molecular-pl...
Reposted by Freddy Boutrot
Out First Release in @science.org
A pollen ligand, SIPS, binds to the female receptor, SRK. SIPS binds to a conserved region of SRK, for interspecific incompatibility, unlike the self-incompatibility factor, which binds to a different, variable region
www.science.org/doi/10.1126/...
#PlantScience
A pollen ligand, SIPS, binds to the female receptor, SRK. SIPS binds to a conserved region of SRK, for interspecific incompatibility, unlike the self-incompatibility factor, which binds to a different, variable region
www.science.org/doi/10.1126/...
#PlantScience
Pan-family pollen signals control an interspecific stigma barrier across Brassicaceae species
Pre-zygotic interspecific incompatibility prevents hybridization between species limiting interbreeding strategies for crop improvement using wild relatives. The Brassica rapa female self-incompatibil...
www.science.org
November 24, 2025 at 2:45 PM
Out First Release in @science.org
A pollen ligand, SIPS, binds to the female receptor, SRK. SIPS binds to a conserved region of SRK, for interspecific incompatibility, unlike the self-incompatibility factor, which binds to a different, variable region
www.science.org/doi/10.1126/...
#PlantScience
A pollen ligand, SIPS, binds to the female receptor, SRK. SIPS binds to a conserved region of SRK, for interspecific incompatibility, unlike the self-incompatibility factor, which binds to a different, variable region
www.science.org/doi/10.1126/...
#PlantScience
Reposted by Freddy Boutrot
PRESS RELEASE – Dr Hassan Salem to lead independent research group on plant-insect interactions
Following an international search, we are delighted to announce that Dr Hassan Salem @hassansalem.bsky.social will be joining us in early 2026: www.jic.ac.uk/press-releas...
Following an international search, we are delighted to announce that Dr Hassan Salem @hassansalem.bsky.social will be joining us in early 2026: www.jic.ac.uk/press-releas...
November 24, 2025 at 4:11 PM
PRESS RELEASE – Dr Hassan Salem to lead independent research group on plant-insect interactions
Following an international search, we are delighted to announce that Dr Hassan Salem @hassansalem.bsky.social will be joining us in early 2026: www.jic.ac.uk/press-releas...
Following an international search, we are delighted to announce that Dr Hassan Salem @hassansalem.bsky.social will be joining us in early 2026: www.jic.ac.uk/press-releas...
Reposted by Freddy Boutrot
I just published: Gene Editing: Precision Breeding Regulations Now Live
On 13 November 2025, UK regulations for precision bred plants came into effect. We can now register precision bred plants, such as those with disease resistance and reduced reliance on fungicides.
medium.com/p/gene-editi...
On 13 November 2025, UK regulations for precision bred plants came into effect. We can now register precision bred plants, such as those with disease resistance and reduced reliance on fungicides.
medium.com/p/gene-editi...
Gene Editing: Precision Breeding Regulations Now Live
FIRST PUBLISHED: 14.11.25 BY LAURA TURCHI AND MIA CERFONTEYN | THE SAINSBURY LABORATORY
medium.com
November 25, 2025 at 2:21 PM
I just published: Gene Editing: Precision Breeding Regulations Now Live
On 13 November 2025, UK regulations for precision bred plants came into effect. We can now register precision bred plants, such as those with disease resistance and reduced reliance on fungicides.
medium.com/p/gene-editi...
On 13 November 2025, UK regulations for precision bred plants came into effect. We can now register precision bred plants, such as those with disease resistance and reduced reliance on fungicides.
medium.com/p/gene-editi...
Reposted by Freddy Boutrot
📣NEWS: We are delighted to share that Dr Aileen Berasategui @berasymbionts.bsky.social will join us as a new group leader next year.
“Aileen is an exceptionally talented scientist and brings new expertise to TSL in plant-insect-fungal interactions” says @talbotlabtsl.bsky.social
buff.ly/kRs4ASU
“Aileen is an exceptionally talented scientist and brings new expertise to TSL in plant-insect-fungal interactions” says @talbotlabtsl.bsky.social
buff.ly/kRs4ASU
November 24, 2025 at 1:00 PM
📣NEWS: We are delighted to share that Dr Aileen Berasategui @berasymbionts.bsky.social will join us as a new group leader next year.
“Aileen is an exceptionally talented scientist and brings new expertise to TSL in plant-insect-fungal interactions” says @talbotlabtsl.bsky.social
buff.ly/kRs4ASU
“Aileen is an exceptionally talented scientist and brings new expertise to TSL in plant-insect-fungal interactions” says @talbotlabtsl.bsky.social
buff.ly/kRs4ASU
Reposted by Freddy Boutrot
Today is a big day as the Precision Breeding Act comes into force 🌱
@kamounlab.bsky.social: “This is a milestone for UK science and innovation. We now have the regulatory framework to translate discovery into impact — improving crops, strengthening food security, and benefiting society” 🌿
@kamounlab.bsky.social: “This is a milestone for UK science and innovation. We now have the regulatory framework to translate discovery into impact — improving crops, strengthening food security, and benefiting society” 🌿
November 13, 2025 at 5:27 PM
Today is a big day as the Precision Breeding Act comes into force 🌱
@kamounlab.bsky.social: “This is a milestone for UK science and innovation. We now have the regulatory framework to translate discovery into impact — improving crops, strengthening food security, and benefiting society” 🌿
@kamounlab.bsky.social: “This is a milestone for UK science and innovation. We now have the regulatory framework to translate discovery into impact — improving crops, strengthening food security, and benefiting society” 🌿
Reposted by Freddy Boutrot
Enhancing NLR activation by endophytes carrying recognized effectors that are expressed in the presence of ROS. #plantimmunity
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
Genetically engineered plant endophytes broaden effector-triggered immunity
Hou et al. engineer plant endophytes to express effectors that trigger NLR-mediated
ETI upon pathogen infection, regardless of whether pathogens carry recognizable effectors.
The sentinel bacterium ma...
www.cell.com
November 12, 2025 at 4:51 PM
Enhancing NLR activation by endophytes carrying recognized effectors that are expressed in the presence of ROS. #plantimmunity
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
Reposted by Freddy Boutrot
Our editors write:
- "Plant immunity: Engineering RLP receptors from the C side" rdcu.be/ePaS1
A brief highlight of this Article in @natbiotech.nature.com :
"Engineered pattern recognition receptors enhance broad-spectrum plant resistance" about swapping C-term domains rdcu.be/ePaTW
- "Plant immunity: Engineering RLP receptors from the C side" rdcu.be/ePaS1
A brief highlight of this Article in @natbiotech.nature.com :
"Engineered pattern recognition receptors enhance broad-spectrum plant resistance" about swapping C-term domains rdcu.be/ePaTW
November 10, 2025 at 1:30 PM
Our editors write:
- "Plant immunity: Engineering RLP receptors from the C side" rdcu.be/ePaS1
A brief highlight of this Article in @natbiotech.nature.com :
"Engineered pattern recognition receptors enhance broad-spectrum plant resistance" about swapping C-term domains rdcu.be/ePaTW
- "Plant immunity: Engineering RLP receptors from the C side" rdcu.be/ePaS1
A brief highlight of this Article in @natbiotech.nature.com :
"Engineered pattern recognition receptors enhance broad-spectrum plant resistance" about swapping C-term domains rdcu.be/ePaTW
Reposted by Freddy Boutrot
We wrote a review 📖 on hydathode immunity! Learn how bacteria exploit hydathodes to access the vasculature and open questions for future research.
📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)! www.sciencedirect.com/science/arti...
📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)! www.sciencedirect.com/science/arti...
Hydathodes at the forefront of plant immunity against vascular pathogens
Hydathodes are tiny plant organs that form an interface between the leaf surface and xylem vasculature. They facilitate excretion of xylem fluid under…
www.sciencedirect.com
November 4, 2025 at 10:43 AM
We wrote a review 📖 on hydathode immunity! Learn how bacteria exploit hydathodes to access the vasculature and open questions for future research.
📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)! www.sciencedirect.com/science/arti...
📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)! www.sciencedirect.com/science/arti...
Reposted by Freddy Boutrot
Plz RP. Come join us at @slcuplants.bsky.social @cam.ac.uk to study effector-targeted plant processes impacting plant cell biology and development.
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
November 6, 2025 at 6:51 PM
Plz RP. Come join us at @slcuplants.bsky.social @cam.ac.uk to study effector-targeted plant processes impacting plant cell biology and development.
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
Reposted by Freddy Boutrot
Cool new paper on receptor specificity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Two residues reprogram immunity receptors for nitrogen-fixing symbiosis - Nature
An investigation of plant receptor-like kinases identifies regions of these proteins that control whether immune or symbiotic signalling pathways are activated, with minimal changes to specific r...
www.nature.com
November 6, 2025 at 3:26 PM
Cool new paper on receptor specificity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Freddy Boutrot
Thrilled to share our latest review on receptor kinase processing in plants! 🌱
Huge congratulations to @adithya1972.bsky.social and Anna for leading this work, and a big thank you to our fantastic collaborator Martina-Ried Lasi for making this a truly rewarding team effort!
Huge congratulations to @adithya1972.bsky.social and Anna for leading this work, and a big thank you to our fantastic collaborator Martina-Ried Lasi for making this a truly rewarding team effort!
Shedding light on receptor kinase processing
journals.plos.org
November 4, 2025 at 8:25 AM
Thrilled to share our latest review on receptor kinase processing in plants! 🌱
Huge congratulations to @adithya1972.bsky.social and Anna for leading this work, and a big thank you to our fantastic collaborator Martina-Ried Lasi for making this a truly rewarding team effort!
Huge congratulations to @adithya1972.bsky.social and Anna for leading this work, and a big thank you to our fantastic collaborator Martina-Ried Lasi for making this a truly rewarding team effort!
Reposted by Freddy Boutrot
Postdoc position in my lab in Cologne starting early next year or latest in spring to get this exciting project started.
jobportal.uni-koeln.de/ausschreibun...
jobportal.uni-koeln.de/ausschreibun...
jobportal.uni-koeln.de
November 2, 2025 at 10:27 AM
Postdoc position in my lab in Cologne starting early next year or latest in spring to get this exciting project started.
jobportal.uni-koeln.de/ausschreibun...
jobportal.uni-koeln.de/ausschreibun...
Reposted by Freddy Boutrot
🚀 New preprint!
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
Natural variation in regulatory code revealed through Bayesian analysis of plant pan-genomes and pan-transcriptomes
Understanding the genetic code of cis-regulatory elements (CREs) is essential for engineering gene expression and modulating agronomic traits in crops. In plants, CREs underlying rapid evolution of ge...
biorxiv.org
October 29, 2025 at 4:47 PM
🚀 New preprint!
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱
🔗 biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics #GeneRegulation #Maize #Soybean
Reposted by Freddy Boutrot
The work is led by @weiweibio.bsky.social, a talented postdoc looking for faculty positions now and conceptualized both computational prediction and in lab validation. Computational implementation is a collaboration with Xing Wu, postdoc with @mexpositoalonso.bsky.social
Qs - contact us 💻🌱🧬
Qs - contact us 💻🌱🧬
October 29, 2025 at 4:55 PM
The work is led by @weiweibio.bsky.social, a talented postdoc looking for faculty positions now and conceptualized both computational prediction and in lab validation. Computational implementation is a collaboration with Xing Wu, postdoc with @mexpositoalonso.bsky.social
Qs - contact us 💻🌱🧬
Qs - contact us 💻🌱🧬
Reposted by Freddy Boutrot
N-hydroxy-pipecolic acid-mediated signal transduction and resistance requires DAWDLE url: academic.oup.com/plphys/artic...
N-hydroxy-pipecolic acid-mediated signal transduction and resistance requires DAWDLE
The Arabidopsis gene DAWDLE activates systemic acquired resistance by regulating immune-related genes induced by N-hydroxy-pipecolic acid.
academic.oup.com
October 27, 2025 at 4:13 PM
N-hydroxy-pipecolic acid-mediated signal transduction and resistance requires DAWDLE url: academic.oup.com/plphys/artic...
Reposted by Freddy Boutrot
Excited that our paper was just published! It's a revised version with new insights compared to the preprint. Thanks everyone from the @carahaney.bsky.social Lab!
www.cell.com/cell-reports...
www.cell.com/cell-reports...
A bacterial exotoxin-triggered plant immune response restricts pathogen growth
Thoms et al. demonstrate that perception of a bacterial exotoxin allows plants to
distinguish between closely related microbiota, which has consequences for rhizosphere
microbiome structure and functi...
www.cell.com
October 23, 2025 at 4:17 PM
Excited that our paper was just published! It's a revised version with new insights compared to the preprint. Thanks everyone from the @carahaney.bsky.social Lab!
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by Freddy Boutrot
Simon's mutant finally published! Well done, Satoko' lab with Harro, Tobimatsu, Tohge collaborations. Glucosylation of endogenous haustorium-inducing factors underpins kin avoidance in parasitic plants | Science www.science.org/doi/10.1126/...
Glucosylation of endogenous haustorium-inducing factors underpins kin avoidance in parasitic plants
Parasitic plants rarely attack themselves, suggesting the existence of a kin-avoidance mechanism. In the root parasitic plant Phtheirospermum japonicum, prehaustorium formation is triggered by host-se...
www.science.org
October 24, 2025 at 12:29 AM
Simon's mutant finally published! Well done, Satoko' lab with Harro, Tobimatsu, Tohge collaborations. Glucosylation of endogenous haustorium-inducing factors underpins kin avoidance in parasitic plants | Science www.science.org/doi/10.1126/...
Reposted by Freddy Boutrot
Humbly share our latest work led by @himanshuchhillar.bsky.social my phd student
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
Uncoupling hypersensitive cell death response and disease resistance activated by effector-triggered immunity https://www.biorxiv.org/content/10.1101/2025.10.22.683861v1
October 23, 2025 at 11:51 PM
Humbly share our latest work led by @himanshuchhillar.bsky.social my phd student
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social