Genes & Development
@genesdev.bsky.social
G&D publishes high-quality research in molecular biology, cancer biology, development, neuroscience and related fields. In addition, G&D also publishes comprehensive Review Articles, Perspectives and Outlooks written by leading scientists.
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🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review, and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2.toc
New Outlook, Review, and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2.toc
RESEARCH PAPER: An intrinsically disordered region of Drosha selectively promotes miRNA biogenesis independent of tissue-specific Microprocessor condensates
By Yang et al., and Katherine McJunkin
➡️ https://genesdev.cshlp.org/content/40/1-2/26.abstract
#IDR #miRNA #Microprocessor #smallRNA
By Yang et al., and Katherine McJunkin
➡️ https://genesdev.cshlp.org/content/40/1-2/26.abstract
#IDR #miRNA #Microprocessor #smallRNA
January 12, 2026 at 6:55 PM
RESEARCH PAPER: An intrinsically disordered region of Drosha selectively promotes miRNA biogenesis independent of tissue-specific Microprocessor condensates
By Yang et al., and Katherine McJunkin
➡️ https://genesdev.cshlp.org/content/40/1-2/26.abstract
#IDR #miRNA #Microprocessor #smallRNA
By Yang et al., and Katherine McJunkin
➡️ https://genesdev.cshlp.org/content/40/1-2/26.abstract
#IDR #miRNA #Microprocessor #smallRNA
REVIEW: Mutant p53: evolving perspectives
By Gizem Efe, Katherine Cunningham, Anil K. Rustgi, Carol Prives, James J. Manfredi, and Francisco J. Sánchez-Rivera
➡️ https://genesdev.cshlp.org/content/40/1-2/43.full
#cancer #mutation #p53
By Gizem Efe, Katherine Cunningham, Anil K. Rustgi, Carol Prives, James J. Manfredi, and Francisco J. Sánchez-Rivera
➡️ https://genesdev.cshlp.org/content/40/1-2/43.full
#cancer #mutation #p53
January 9, 2026 at 6:01 PM
REVIEW: Mutant p53: evolving perspectives
By Gizem Efe, Katherine Cunningham, Anil K. Rustgi, Carol Prives, James J. Manfredi, and Francisco J. Sánchez-Rivera
➡️ https://genesdev.cshlp.org/content/40/1-2/43.full
#cancer #mutation #p53
By Gizem Efe, Katherine Cunningham, Anil K. Rustgi, Carol Prives, James J. Manfredi, and Francisco J. Sánchez-Rivera
➡️ https://genesdev.cshlp.org/content/40/1-2/43.full
#cancer #mutation #p53
📽 G&D Tapes 📽
G&D Author, Alexandra Bergfort, tells us about their new study in #genesdev showing how the EJC coordinates splicing of exon blocks
Learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full
Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing
G&D Author, Alexandra Bergfort, tells us about their new study in #genesdev showing how the EJC coordinates splicing of exon blocks
Learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full
Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing
January 8, 2026 at 7:01 PM
📽 G&D Tapes 📽
G&D Author, Alexandra Bergfort, tells us about their new study in #genesdev showing how the EJC coordinates splicing of exon blocks
Learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full
Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing
G&D Author, Alexandra Bergfort, tells us about their new study in #genesdev showing how the EJC coordinates splicing of exon blocks
Learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full
Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing
RESEARCH PAPER: The exon junction complex coordinates the cotranscriptional inclusion of blocks of neighboring exons
By Bergfort et al., and Karla Neugebauer
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full
Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing
By Bergfort et al., and Karla Neugebauer
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full
Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing
January 8, 2026 at 4:01 PM
RESEARCH PAPER: The exon junction complex coordinates the cotranscriptional inclusion of blocks of neighboring exons
By Bergfort et al., and Karla Neugebauer
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full
Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing
By Bergfort et al., and Karla Neugebauer
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full
Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing
Reposted by Genes & Development
G+D together with JHU worked to put together this cool video describing our latest work! Check it out!
📽 G&D Tapes 📽
G&D Author, Christina McNerney, tells us about their new study in #genesdev showing how enzyme DIO3 coordinates photoreceptor development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/40/1-2/70.full
Christina McNerney Bob Johnston Johns Hopkins University
#vision
G&D Author, Christina McNerney, tells us about their new study in #genesdev showing how enzyme DIO3 coordinates photoreceptor development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/40/1-2/70.full
Christina McNerney Bob Johnston Johns Hopkins University
#vision
January 7, 2026 at 11:55 PM
G+D together with JHU worked to put together this cool video describing our latest work! Check it out!
📽 G&D Tapes 📽
G&D Author, Christina McNerney, tells us about their new study in #genesdev showing how enzyme DIO3 coordinates photoreceptor development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/40/1-2/70.full
Christina McNerney Bob Johnston Johns Hopkins University
#vision
G&D Author, Christina McNerney, tells us about their new study in #genesdev showing how enzyme DIO3 coordinates photoreceptor development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/40/1-2/70.full
Christina McNerney Bob Johnston Johns Hopkins University
#vision
January 7, 2026 at 7:01 PM
📽 G&D Tapes 📽
G&D Author, Christina McNerney, tells us about their new study in #genesdev showing how enzyme DIO3 coordinates photoreceptor development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/40/1-2/70.full
Christina McNerney Bob Johnston Johns Hopkins University
#vision
G&D Author, Christina McNerney, tells us about their new study in #genesdev showing how enzyme DIO3 coordinates photoreceptor development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/40/1-2/70.full
Christina McNerney Bob Johnston Johns Hopkins University
#vision
RESEARCH PAPER: DIO3 coordinates photoreceptor development timing and fate stability in human retinal organoids
By McNerney et al., and Robert Johnston, Jr.
➡️ https://genesdev.cshlp.org/content/40/1-2/70.full
Bob Johnston Christina McNerney Johns Hopkins University
#photoreceptor #hormone #neurons
By McNerney et al., and Robert Johnston, Jr.
➡️ https://genesdev.cshlp.org/content/40/1-2/70.full
Bob Johnston Christina McNerney Johns Hopkins University
#photoreceptor #hormone #neurons
January 7, 2026 at 4:01 PM
RESEARCH PAPER: DIO3 coordinates photoreceptor development timing and fate stability in human retinal organoids
By McNerney et al., and Robert Johnston, Jr.
➡️ https://genesdev.cshlp.org/content/40/1-2/70.full
Bob Johnston Christina McNerney Johns Hopkins University
#photoreceptor #hormone #neurons
By McNerney et al., and Robert Johnston, Jr.
➡️ https://genesdev.cshlp.org/content/40/1-2/70.full
Bob Johnston Christina McNerney Johns Hopkins University
#photoreceptor #hormone #neurons
RESEARCH PAPER: Histone modification cross-talk and protein complex diversification confer plasticity to Polycomb repression
By Bonnet et al., and Jürg Müller
➡️ https://genesdev.cshlp.org/content/40/1-2/43.full
Max Planck Institute of Biochemistry
#polycomb #histone #chromatin #drosophila
By Bonnet et al., and Jürg Müller
➡️ https://genesdev.cshlp.org/content/40/1-2/43.full
Max Planck Institute of Biochemistry
#polycomb #histone #chromatin #drosophila
January 6, 2026 at 7:00 PM
RESEARCH PAPER: Histone modification cross-talk and protein complex diversification confer plasticity to Polycomb repression
By Bonnet et al., and Jürg Müller
➡️ https://genesdev.cshlp.org/content/40/1-2/43.full
Max Planck Institute of Biochemistry
#polycomb #histone #chromatin #drosophila
By Bonnet et al., and Jürg Müller
➡️ https://genesdev.cshlp.org/content/40/1-2/43.full
Max Planck Institute of Biochemistry
#polycomb #histone #chromatin #drosophila
🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review, and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2.toc
New Outlook, Review, and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2.toc
January 5, 2026 at 7:01 PM
🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review, and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2.toc
New Outlook, Review, and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2.toc
Wrapping up G&D 2025 on a high note!!!
Stay tuned for another great year of exciting research.
HAPPY NEW YEAR!!!
Stay tuned for another great year of exciting research.
HAPPY NEW YEAR!!!
January 5, 2026 at 6:38 PM
Wrapping up G&D 2025 on a high note!!!
Stay tuned for another great year of exciting research.
HAPPY NEW YEAR!!!
Stay tuned for another great year of exciting research.
HAPPY NEW YEAR!!!
⏪ G&D RECAP ⏪
🗓️ December 2025
RESEARCH PAPER: Multiple human enhancer RNAs contain long translated open reading frames
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #chromatin #DNAdamage #RNAprocessing #nucleus
🗓️ December 2025
RESEARCH PAPER: Multiple human enhancer RNAs contain long translated open reading frames
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #chromatin #DNAdamage #RNAprocessing #nucleus
December 31, 2025 at 7:00 PM
⏪ G&D RECAP ⏪
🗓️ December 2025
RESEARCH PAPER: Multiple human enhancer RNAs contain long translated open reading frames
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #chromatin #DNAdamage #RNAprocessing #nucleus
🗓️ December 2025
RESEARCH PAPER: Multiple human enhancer RNAs contain long translated open reading frames
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #chromatin #DNAdamage #RNAprocessing #nucleus
⏪ G&D RECAP ⏪
🗓️ November 2025
OUTLOOK: End of the line: a kinetic ruler model for poly(A) tail termination
By Anita Corbett
➡️ https://genesdev.cshlp.org/content/39/21-22/1267.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #ribonucleoprotein
🗓️ November 2025
OUTLOOK: End of the line: a kinetic ruler model for poly(A) tail termination
By Anita Corbett
➡️ https://genesdev.cshlp.org/content/39/21-22/1267.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #ribonucleoprotein
December 30, 2025 at 7:00 PM
⏪ G&D RECAP ⏪
🗓️ November 2025
OUTLOOK: End of the line: a kinetic ruler model for poly(A) tail termination
By Anita Corbett
➡️ https://genesdev.cshlp.org/content/39/21-22/1267.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #ribonucleoprotein
🗓️ November 2025
OUTLOOK: End of the line: a kinetic ruler model for poly(A) tail termination
By Anita Corbett
➡️ https://genesdev.cshlp.org/content/39/21-22/1267.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #ribonucleoprotein
⏪ G&D RECAP ⏪
🗓️ November 2025
RESEARCH PAPER: A kinetic ruler controls mRNA poly(A) tail length
By Gabs et al. and Matti Turtola
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #polyadenylation #ribonucleoprotein #CPAC
🗓️ November 2025
RESEARCH PAPER: A kinetic ruler controls mRNA poly(A) tail length
By Gabs et al. and Matti Turtola
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #polyadenylation #ribonucleoprotein #CPAC
December 30, 2025 at 4:01 PM
⏪ G&D RECAP ⏪
🗓️ November 2025
RESEARCH PAPER: A kinetic ruler controls mRNA poly(A) tail length
By Gabs et al. and Matti Turtola
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #polyadenylation #ribonucleoprotein #CPAC
🗓️ November 2025
RESEARCH PAPER: A kinetic ruler controls mRNA poly(A) tail length
By Gabs et al. and Matti Turtola
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #polyadenylation #ribonucleoprotein #CPAC
⏪ G&D RECAP ⏪
🗓️ October 2025
RESEARCH COMMUNICATION: Structural basis of nucleosome recognition by the conserved Dsup & HMGN nucleosome-binding motif
By Alegrio-Louro et al. and Andres Leschziner
➡️ https://genesdev.cshlp.org/content/39/19-20/1155.full
#proteininteractions #proteinstructure #cryoEM
🗓️ October 2025
RESEARCH COMMUNICATION: Structural basis of nucleosome recognition by the conserved Dsup & HMGN nucleosome-binding motif
By Alegrio-Louro et al. and Andres Leschziner
➡️ https://genesdev.cshlp.org/content/39/19-20/1155.full
#proteininteractions #proteinstructure #cryoEM
December 29, 2025 at 7:00 PM
⏪ G&D RECAP ⏪
🗓️ October 2025
RESEARCH COMMUNICATION: Structural basis of nucleosome recognition by the conserved Dsup & HMGN nucleosome-binding motif
By Alegrio-Louro et al. and Andres Leschziner
➡️ https://genesdev.cshlp.org/content/39/19-20/1155.full
#proteininteractions #proteinstructure #cryoEM
🗓️ October 2025
RESEARCH COMMUNICATION: Structural basis of nucleosome recognition by the conserved Dsup & HMGN nucleosome-binding motif
By Alegrio-Louro et al. and Andres Leschziner
➡️ https://genesdev.cshlp.org/content/39/19-20/1155.full
#proteininteractions #proteinstructure #cryoEM
Best wishes and holiday cheer to our amazing G&D community...
December 24, 2025 at 7:00 PM
Best wishes and holiday cheer to our amazing G&D community...
⏪ G&D RECAP ⏪
🗓️ September 2025
RESEARCH PAPER: Bystander activation across a #TAD boundary supports a cohesin-dependent #transcription cluster model for #enhancer function
By Williamson et al., Wendy Bickmore, and Laura Lettice
➡️ https://genesdev.cshlp.org/content/39/17-18/1012.full
Wendy Bickmore
🗓️ September 2025
RESEARCH PAPER: Bystander activation across a #TAD boundary supports a cohesin-dependent #transcription cluster model for #enhancer function
By Williamson et al., Wendy Bickmore, and Laura Lettice
➡️ https://genesdev.cshlp.org/content/39/17-18/1012.full
Wendy Bickmore
December 24, 2025 at 4:01 PM
⏪ G&D RECAP ⏪
🗓️ September 2025
RESEARCH PAPER: Bystander activation across a #TAD boundary supports a cohesin-dependent #transcription cluster model for #enhancer function
By Williamson et al., Wendy Bickmore, and Laura Lettice
➡️ https://genesdev.cshlp.org/content/39/17-18/1012.full
Wendy Bickmore
🗓️ September 2025
RESEARCH PAPER: Bystander activation across a #TAD boundary supports a cohesin-dependent #transcription cluster model for #enhancer function
By Williamson et al., Wendy Bickmore, and Laura Lettice
➡️ https://genesdev.cshlp.org/content/39/17-18/1012.full
Wendy Bickmore
⏪ G&D RECAP ⏪
🗓️ August 2025
REVIEW: Studying ovarian aging and its health impacts: modern tools and approaches
By Bérénice Benayoun, Alison Kochersberger, and Jennifer Garrison
➡️ https://genesdev.cshlp.org/content/39/15-16/975.full
Bérénice A. Benayoun, PhD Jennifer Garrison
#aging #womenshealth
🗓️ August 2025
REVIEW: Studying ovarian aging and its health impacts: modern tools and approaches
By Bérénice Benayoun, Alison Kochersberger, and Jennifer Garrison
➡️ https://genesdev.cshlp.org/content/39/15-16/975.full
Bérénice A. Benayoun, PhD Jennifer Garrison
#aging #womenshealth
December 23, 2025 at 7:00 PM
⏪ G&D RECAP ⏪
🗓️ August 2025
REVIEW: Studying ovarian aging and its health impacts: modern tools and approaches
By Bérénice Benayoun, Alison Kochersberger, and Jennifer Garrison
➡️ https://genesdev.cshlp.org/content/39/15-16/975.full
Bérénice A. Benayoun, PhD Jennifer Garrison
#aging #womenshealth
🗓️ August 2025
REVIEW: Studying ovarian aging and its health impacts: modern tools and approaches
By Bérénice Benayoun, Alison Kochersberger, and Jennifer Garrison
➡️ https://genesdev.cshlp.org/content/39/15-16/975.full
Bérénice A. Benayoun, PhD Jennifer Garrison
#aging #womenshealth
⏪ G&D RECAP ⏪
🗓️ July 2025
RESEARCH PAPER: Ribosome association inhibits stress-induced gene mRNA localization to stress granules
By Noah Helton, Benjamin Dodd, and Stephanie Moon
➡️ https://genesdev.cshlp.org/content/39/13-14/826.full
Stephanie Moon
#ribosome #stressgranule #translation
🗓️ July 2025
RESEARCH PAPER: Ribosome association inhibits stress-induced gene mRNA localization to stress granules
By Noah Helton, Benjamin Dodd, and Stephanie Moon
➡️ https://genesdev.cshlp.org/content/39/13-14/826.full
Stephanie Moon
#ribosome #stressgranule #translation
December 22, 2025 at 7:00 PM
⏪ G&D RECAP ⏪
🗓️ July 2025
RESEARCH PAPER: Ribosome association inhibits stress-induced gene mRNA localization to stress granules
By Noah Helton, Benjamin Dodd, and Stephanie Moon
➡️ https://genesdev.cshlp.org/content/39/13-14/826.full
Stephanie Moon
#ribosome #stressgranule #translation
🗓️ July 2025
RESEARCH PAPER: Ribosome association inhibits stress-induced gene mRNA localization to stress granules
By Noah Helton, Benjamin Dodd, and Stephanie Moon
➡️ https://genesdev.cshlp.org/content/39/13-14/826.full
Stephanie Moon
#ribosome #stressgranule #translation
📽 G&D Tapes 📽
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
December 19, 2025 at 6:02 PM
📽 G&D Tapes 📽
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development.
Read the full story here:
➡️ https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic Benoit Bruneau Gladstone Institutes
⏪ G&D RECAP ⏪
🗓️ June 2025
RESEARCH PAPER: Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation
By Magesh et al., Stephen Elledge, and Emma Watson
➡️ https://genesdev.cshlp.org/content/39/11-12/770.full
#aneuploidy #cancer #metabolism #chemotherapy
🗓️ June 2025
RESEARCH PAPER: Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation
By Magesh et al., Stephen Elledge, and Emma Watson
➡️ https://genesdev.cshlp.org/content/39/11-12/770.full
#aneuploidy #cancer #metabolism #chemotherapy
December 19, 2025 at 4:01 PM
⏪ G&D RECAP ⏪
🗓️ June 2025
RESEARCH PAPER: Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation
By Magesh et al., Stephen Elledge, and Emma Watson
➡️ https://genesdev.cshlp.org/content/39/11-12/770.full
#aneuploidy #cancer #metabolism #chemotherapy
🗓️ June 2025
RESEARCH PAPER: Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation
By Magesh et al., Stephen Elledge, and Emma Watson
➡️ https://genesdev.cshlp.org/content/39/11-12/770.full
#aneuploidy #cancer #metabolism #chemotherapy
⏪ G&D RECAP ⏪
🗓️ May 2025
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.full
#DNArepair #BRCA1 #nucleases #PARP #cancer
🗓️ May 2025
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.full
#DNArepair #BRCA1 #nucleases #PARP #cancer
December 18, 2025 at 4:01 PM
⏪ G&D RECAP ⏪
🗓️ May 2025
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.full
#DNArepair #BRCA1 #nucleases #PARP #cancer
🗓️ May 2025
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.full
#DNArepair #BRCA1 #nucleases #PARP #cancer
⏪ G&D RECAP ⏪
🗓️ April 2025
OUTLOOK: Where and why have so many metabolic enzymes gone from developing spores of Bacillus subtilis?
By Peter Setlow
➡️ https://genesdev.cshlp.org/content/39/7-8/426.full
#bacteria #sporulation #protease #metabolism #dormancy
🗓️ April 2025
OUTLOOK: Where and why have so many metabolic enzymes gone from developing spores of Bacillus subtilis?
By Peter Setlow
➡️ https://genesdev.cshlp.org/content/39/7-8/426.full
#bacteria #sporulation #protease #metabolism #dormancy
December 17, 2025 at 7:00 PM
⏪ G&D RECAP ⏪
🗓️ April 2025
OUTLOOK: Where and why have so many metabolic enzymes gone from developing spores of Bacillus subtilis?
By Peter Setlow
➡️ https://genesdev.cshlp.org/content/39/7-8/426.full
#bacteria #sporulation #protease #metabolism #dormancy
🗓️ April 2025
OUTLOOK: Where and why have so many metabolic enzymes gone from developing spores of Bacillus subtilis?
By Peter Setlow
➡️ https://genesdev.cshlp.org/content/39/7-8/426.full
#bacteria #sporulation #protease #metabolism #dormancy
⏪ G&D RECAP ⏪
🗓️ April 2025
RESEARCH PAPER: MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore
By Massoni et al., Rivka Isaacson, and Amy Camp
➡️ https://genesdev.cshlp.org/content/39/7-8/510.full
#bacteria #sporulation #protease #metabolism #dormancy
🗓️ April 2025
RESEARCH PAPER: MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore
By Massoni et al., Rivka Isaacson, and Amy Camp
➡️ https://genesdev.cshlp.org/content/39/7-8/510.full
#bacteria #sporulation #protease #metabolism #dormancy
December 17, 2025 at 4:05 PM
⏪ G&D RECAP ⏪
🗓️ April 2025
RESEARCH PAPER: MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore
By Massoni et al., Rivka Isaacson, and Amy Camp
➡️ https://genesdev.cshlp.org/content/39/7-8/510.full
#bacteria #sporulation #protease #metabolism #dormancy
🗓️ April 2025
RESEARCH PAPER: MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore
By Massoni et al., Rivka Isaacson, and Amy Camp
➡️ https://genesdev.cshlp.org/content/39/7-8/510.full
#bacteria #sporulation #protease #metabolism #dormancy
⏪ G&D RECAP ⏪
🗓️ April 2025
RESEARCH PAPER: Developmentally regulated proteolysis by MdfA & ClpCP mediates metabolic differentiation during B. subtilis sporulation
By Riley et al., Javier Lopez-Garrido and Kit Pogliano
➡️ https://genesdev.cshlp.org/content/39/7-8/524.full
#bacteria #spore #dormancy
🗓️ April 2025
RESEARCH PAPER: Developmentally regulated proteolysis by MdfA & ClpCP mediates metabolic differentiation during B. subtilis sporulation
By Riley et al., Javier Lopez-Garrido and Kit Pogliano
➡️ https://genesdev.cshlp.org/content/39/7-8/524.full
#bacteria #spore #dormancy
December 17, 2025 at 4:01 PM
⏪ G&D RECAP ⏪
🗓️ April 2025
RESEARCH PAPER: Developmentally regulated proteolysis by MdfA & ClpCP mediates metabolic differentiation during B. subtilis sporulation
By Riley et al., Javier Lopez-Garrido and Kit Pogliano
➡️ https://genesdev.cshlp.org/content/39/7-8/524.full
#bacteria #spore #dormancy
🗓️ April 2025
RESEARCH PAPER: Developmentally regulated proteolysis by MdfA & ClpCP mediates metabolic differentiation during B. subtilis sporulation
By Riley et al., Javier Lopez-Garrido and Kit Pogliano
➡️ https://genesdev.cshlp.org/content/39/7-8/524.full
#bacteria #spore #dormancy
⏪ G&D RECAP ⏪
🗓️ March 2025
RESEARCH PAPER: Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
By Huang et al. and Wouter de Laat
➡️ https://genesdev.cshlp.org/content/39/5-6/348.full
#enhancer #3Dgenome #CTCF #TADs #chromatin
🗓️ March 2025
RESEARCH PAPER: Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
By Huang et al. and Wouter de Laat
➡️ https://genesdev.cshlp.org/content/39/5-6/348.full
#enhancer #3Dgenome #CTCF #TADs #chromatin
December 16, 2025 at 7:01 PM
⏪ G&D RECAP ⏪
🗓️ March 2025
RESEARCH PAPER: Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
By Huang et al. and Wouter de Laat
➡️ https://genesdev.cshlp.org/content/39/5-6/348.full
#enhancer #3Dgenome #CTCF #TADs #chromatin
🗓️ March 2025
RESEARCH PAPER: Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
By Huang et al. and Wouter de Laat
➡️ https://genesdev.cshlp.org/content/39/5-6/348.full
#enhancer #3Dgenome #CTCF #TADs #chromatin