New Outlook, Review and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
REVIEW: Cohesin in 3D: development, differentiation, and disease
By Maria Solé-Ferran and Ana Losada
➡️ https://genesdev.cshlp.org/content/39/11-12/679.abstract
#cohesin #chromatin #chromosome #development #cohesinopathy
REVIEW: Cohesin in 3D: development, differentiation, and disease
By Maria Solé-Ferran and Ana Losada
➡️ https://genesdev.cshlp.org/content/39/11-12/679.abstract
#cohesin #chromatin #chromosome #development #cohesinopathy
RESEARCH PAPER: Restrictor synergizes with Symplekin and PNUTS to terminate extragenic transcription
By Russo et al., and Gioacchino Natoli
➡️ https://genesdev.cshlp.org/content/37/21-24/1017.abstract
#transcription #transcriptiontermination #restrictor #yeast #noncodingRNA
RESEARCH PAPER: Restrictor synergizes with Symplekin and PNUTS to terminate extragenic transcription
By Russo et al., and Gioacchino Natoli
➡️ https://genesdev.cshlp.org/content/37/21-24/1017.abstract
#transcription #transcriptiontermination #restrictor #yeast #noncodingRNA
REVIEW: CST–Polα/Primase: the second telomere maintenance machine
By Sarah Cai and Titia de Lange
➡️ https://genesdev.cshlp.org/content/37/13-14/555.abstract
#telomere #telomerase #strandsynthesis #polymerase⍺ #primase
REVIEW: CST–Polα/Primase: the second telomere maintenance machine
By Sarah Cai and Titia de Lange
➡️ https://genesdev.cshlp.org/content/37/13-14/555.abstract
#telomere #telomerase #strandsynthesis #polymerase⍺ #primase
RESEARCH PAPER: Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate
By Franklin et al., and Sihem Cheloufi
➡️ https://genesdev.cshlp.org/content/39/9-10/652.abstract
#histones #transcription #replication
RESEARCH PAPER: Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate
By Franklin et al., and Sihem Cheloufi
➡️ https://genesdev.cshlp.org/content/39/9-10/652.abstract
#histones #transcription #replication
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.abstract
#DNArepair #BRCA1 #nucleases #PARP #cancer
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.abstract
#DNArepair #BRCA1 #nucleases #PARP #cancer
RESEARCH PAPER: Hao-Fountain syndrome protein USP7 controls neuronal differentiation via BCOR–ncPRC1.1
By Wolf van der Meer et al., Jeroen Demmers, Yaser Atlasi and Peter Verrijzer
➡️ https://genesdev.cshlp.org/content/39/5-6/401.abstract
#neurodevelopment #epigenetics #polycomb
RESEARCH PAPER: Hao-Fountain syndrome protein USP7 controls neuronal differentiation via BCOR–ncPRC1.1
By Wolf van der Meer et al., Jeroen Demmers, Yaser Atlasi and Peter Verrijzer
➡️ https://genesdev.cshlp.org/content/39/5-6/401.abstract
#neurodevelopment #epigenetics #polycomb
RESEARCH PAPER: ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease
By Song et al. and Wei Gu
➡️ https://genesdev.cshlp.org/content/37/5-6/204.abstract
#huntingtonsdisease #ferroptosis #huntingtin #oxidativestress #ROS
RESEARCH PAPER: ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease
By Song et al. and Wei Gu
➡️ https://genesdev.cshlp.org/content/37/5-6/204.abstract
#huntingtonsdisease #ferroptosis #huntingtin #oxidativestress #ROS
(1933–2025)
By Thoru Pederson
➡️ https://tinyurl.com/gd353471OA
*Photo courtesy of the Cold Spring Harbor Laboratory Archives.
(1933–2025)
By Thoru Pederson
➡️ https://tinyurl.com/gd353471OA
*Photo courtesy of the Cold Spring Harbor Laboratory Archives.
By Anita Corbett
➡️ https://genesdev.cshlp.org/content/39/21-22/1267.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #polyadenylation #ribonucleoprotein #CPAC
By Anita Corbett
➡️ https://genesdev.cshlp.org/content/39/21-22/1267.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #polyadenylation #ribonucleoprotein #CPAC
By Matias et al. and Margaret Fuller
➡️ https://genesdev.cshlp.org/content/39/21-22/1318.abstract
#chromatin #transcription #Drosophila #stemcells #germline
By Matias et al. and Margaret Fuller
➡️ https://genesdev.cshlp.org/content/39/21-22/1318.abstract
#chromatin #transcription #Drosophila #stemcells #germline
By Gabs et al. and Matti Turtola
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #polyadenylation #ribonucleoprotein #CPAC
By Gabs et al. and Matti Turtola
➡️ https://genesdev.cshlp.org/content/39/21-22/1377.full
#RNAprocessing #mRNA #polyadenylation #ribonucleoprotein #CPAC
By Carmen Birchmeier
➡️ https://genesdev.cshlp.org/content/39/21-22/1269.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/21-22/1299.abstract
#transcription #muscle #stemcells #openaccess
By Carmen Birchmeier
➡️ https://genesdev.cshlp.org/content/39/21-22/1269.full
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/21-22/1299.abstract
#transcription #muscle #stemcells #openaccess
By Deevy et al., Eric Conway and Adrian Bracken
➡️ https://genesdev.cshlp.org/content/39/21-22/1355.full
Eric Conway
Adrian Bracken
#weaversyndrome #ezh2 #polycomb #mutation #congenitaldisorder #onthecover
By Deevy et al., Eric Conway and Adrian Bracken
➡️ https://genesdev.cshlp.org/content/39/21-22/1355.full
Eric Conway
Adrian Bracken
#weaversyndrome #ezh2 #polycomb #mutation #congenitaldisorder #onthecover
By Mishra et al. and Lingbo Zhang
➡️ https://genesdev.cshlp.org/content/39/21-22/1271.abstract
#cancer #metabolism #vitamin #cancertherapy #cancermetabolism #immune
By Mishra et al. and Lingbo Zhang
➡️ https://genesdev.cshlp.org/content/39/21-22/1271.abstract
#cancer #metabolism #vitamin #cancertherapy #cancermetabolism #immune
By Yang et al., and Xiaosu Li
➡️ https://genesdev.cshlp.org/content/39/21-22/1338.abstract
#glia #braindevelopment #neuron #neurodevelopment #neuronalprogenitor #neuralstemcell #epigenetics
By Yang et al., and Xiaosu Li
➡️ https://genesdev.cshlp.org/content/39/21-22/1338.abstract
#glia #braindevelopment #neuron #neurodevelopment #neuronalprogenitor #neuralstemcell #epigenetics
By Nicoletti, Massenet et al., Luca Caputo and Pier Lorenzo Puri
➡️ https://genesdev.cshlp.org/content/39/21-22/1299.abstract
#transcription #trancriptionfactor #epigenetics #muscle #stemcells
By Nicoletti, Massenet et al., Luca Caputo and Pier Lorenzo Puri
➡️ https://genesdev.cshlp.org/content/39/21-22/1299.abstract
#transcription #trancriptionfactor #epigenetics #muscle #stemcells
G&D author, Haoming Yu tells us about their new study in #genesdev that uses epigenetic editing to probe the role of H3K4me3 at intergenic regulatory elements.
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/21-22/1290.full
Bluma Lesch
@haomingyu.bsky.social
G&D author, Haoming Yu tells us about their new study in #genesdev that uses epigenetic editing to probe the role of H3K4me3 at intergenic regulatory elements.
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/21-22/1290.full
Bluma Lesch
@haomingyu.bsky.social
By Yu et. al and Bluma Lesch
➡️ https://genesdev.cshlp.org/content/39/21-22/1290.full
Bluma Lesch
@haomingyu.bsky.social
#transcription #epigenetics #histones #histonePTMs #methylation #enhancers
By Yu et. al and Bluma Lesch
➡️ https://genesdev.cshlp.org/content/39/21-22/1290.full
Bluma Lesch
@haomingyu.bsky.social
#transcription #epigenetics #histones #histonePTMs #methylation #enhancers
New Outlook, Review and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
New Outlook, Review and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
By Turn et al. and Peter Jackson
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1241.abstract
By Turn et al. and Peter Jackson
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1241.abstract
By Sakhawala et al. and Katherine McJunkin
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1198.abstract
By Sakhawala et al. and Katherine McJunkin
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1198.abstract
By He et al. and Michael Matunis
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1182.abstract
By He et al. and Michael Matunis
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1182.abstract
By Briggs et al. and James Burke
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➡️ https://genesdev.cshlp.org/content/39/19-20/1162.abstract
By Briggs et al. and James Burke
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1162.abstract
By Alegrio-Louro et al. and Andres Leschziner
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1155.full
By Alegrio-Louro et al. and Andres Leschziner
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1155.full
By Aleah Goldberg, Maria Trifas and Teresa Davoli
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1132.abstract
By Aleah Goldberg, Maria Trifas and Teresa Davoli
Learn more here:
➡️ https://genesdev.cshlp.org/content/39/19-20/1132.abstract