Rémi Goupil
@goupilremi.bsky.social
860 followers 180 following 44 posts
Nephrologist and FRQS clinician-scientist in hypertension at the Hôpital du Sacré-Coeur de Montréal. Associate Clinical Prof at Université de Montréal. Proud father of four.
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Reposted by Rémi Goupil
giaconajohn.bsky.social
Subclinical primary aldosteronism is an under-recognized driver of cardiovascular risk. Could it be a new target for CV prevention? Read our Circulation editorial —>
Reposted by Rémi Goupil
jesslin23.bsky.social
Such a great opportunity, to be involved in an editorial on the most recent evidence for Subclinical Primary Aldosteronism. Thank you to @drwanpen.bsky.social @giaconajohn.bsky.social

Go check it out!! www.ahajournals.org/doi/10.1161/...
Reposted by Rémi Goupil
hswapnil.medsky.social
Doesn’t take too long!

All those who think it is hard to measure BP properly in the clinic please fill out this survey from @goupilremi.bsky.social

#NephSky #CardioSky #MedSky
goupilremi.bsky.social
🚨 Survey Alert!
Standardized office BP measurements are recommended everywhere, but still underused.
We want to hear from you: what are the barriers to using them as a routine in clinical practice?

Click here to read the consent form and take the survey:
redcap.link/barriers.to....
goupilremi.bsky.social
🚨 Survey Alert!
Standardized office BP measurements are recommended everywhere, but still underused.
We want to hear from you: what are the barriers to using them as a routine in clinical practice?

Click here to read the consent form and take the survey:
redcap.link/barriers.to....
Reposted by Rémi Goupil
spjuraschek.bsky.social
Another great read on implementation of the new BP guidelines:

Implementing the 2025 Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: How to Translate Team-Based Care of Hypertension to the Real World www.ahajournals.org/doi/10.1161/...
American Heart Association Journals
www.ahajournals.org
goupilremi.bsky.social
Measuring BP over a sweater sleeve? As accurate as the optimal method!
But using a non-validated device or leaving the arm unsupported? Expect higher readings than what’s actually seen on awake ABPM.

Underpowered pilot study, so hoping to confirm this in larger trials soon!
goupilremi.bsky.social
Just published in Hypertension! In a pilot study, we tested whether common "shortcuts" of the standardized AOBP measurement procedure affect accuracy, assessed with daytime ABPM.
www.ahajournals.org/doi/10.1161/...
Simplifications of the Standardized BP Measurement Procedure and Accuracy: The SIMPLE-AOBP Randomized Cross-Over Trial | Hypertension
www.ahajournals.org
Reposted by Rémi Goupil
spjuraschek.bsky.social
Cool trial (thx Dr. Cluett for sharing!). I love the within person comparison.
@goupilremi.bsky.social @deanpicone.bsky.social

Random ? (having enjoyed reading & doing similar studies): Is accuracy at a single time enough? Should we worry about BP change too?

www.ahajournals.org/doi/10.1161/...
goupilremi.bsky.social
Thanks! I wonder myself what the « gold standard » should be for BP accuracy. I don’t think it’s auscultatory BP (even for validation studies 🔥😱). We chose awake ABPM as it’s the most objective. We just launched a larger study on non-validated devices accuracy, so we’ll know more soon!
goupilremi.bsky.social
But we know bedtime BP meds reduce nighttime BP better than morning BP meds. The problem is it doesn’t change outcomes. Nighttime BP is not a good surrogate marker of CVD!
goupilremi.bsky.social
Another great finding with the @cartagene.bsky.social cohort, and an incredible collaboration with Greg Hundemer and many other colleagues.
goupilremi.bsky.social
We show that the thresholds associated with the best discrimination for MACE risk were renin < 4.0 ng/L and ARR > 70 pmol/L per ng/L, both exhibiting a 2-fold higher risk of MACE.
goupilremi.bsky.social
Our new data on subclinical PA and MACE is out in Circulation! For the first time, we show that renin-independant aldosterone production is associated with an increased risk of MACE independently of BP, in people mostly normotensive with low CV risk.
www.ahajournals.org/doi/full/10....
goupilremi.bsky.social
You just made me cry…
goupilremi.bsky.social
It’s an excerpt from their book. Starts with « A few months ago »… it was in 2017. Sad that Stat published this outdated piece like it’s late-breaking news.
goupilremi.bsky.social
Always important to individualize. This situation is not common, and I’m not sure there is any data that shows we should treat (or not treat).
goupilremi.bsky.social
That’s what we just did in Canada! Target is SBP < 130 mmHg for all

www.cmaj.ca/content/197/...
Reposted by Rémi Goupil
rosstsuyuki.bsky.social
A new era in hypertension management-Simplified and practical guidelines. Here is what you need to know: 130/80mmHg and ARB-diuretic combination.
goupilremi.bsky.social
No, the target is SBP < 130. Once it’s achieved, no specific intervention is recommended even if DBP remains « high ».
goupilremi.bsky.social
Next up, the comprehensive Hypertension Canada guidelines, where we will dive into specific subjects.
pubmed.ncbi.nlm.nih.gov/39461618/

Thanks to all involved, including committee members, patient-partners and external reviewers.
goupilremi.bsky.social
Lastly, we thank all who provided comments and questions in the public external review phase. This allowed the committee to greatly improve the Guideline. Answers are provided to frequently received questions here: www.cmaj.ca/content/cmaj...
www.cmaj.ca
goupilremi.bsky.social
We all know patients need to be involved in the care and to help, a Patient guideline has been developped:
www.cmaj.ca/content/cmaj...
www.cmaj.ca
goupilremi.bsky.social
The help implement these recommendations, a HEARTS-style treatment algorithm as is provided:
goupilremi.bsky.social
Treatment (2):
7- If pharmacotherapy is needed, start with low-dose combination therapy (2 of ACEi/ARB, thiazide/thiazide-like, long-acting dihydropyridine CCB) (IB)
8- If BP still above target, combine the above three classes (IB)
9- If still high, start spironolactone (IIB)