Swapnil Hiremath 🍁🇨🇦
@hswapnil.medsky.social
Nephrologist = kidney doctor
MD, MPH
Professor, University of Ottawa/Ottawa Hospital 🇨🇦
He/Him/His
#NephJC co-creator; @FreelyFiltered.bsky.social pod panelist; KICR EiC
https://www.swapnilhiremath.com
MD, MPH
Professor, University of Ottawa/Ottawa Hospital 🇨🇦
He/Him/His
#NephJC co-creator; @FreelyFiltered.bsky.social pod panelist; KICR EiC
https://www.swapnilhiremath.com
Pinned
If you are a nephrology or kidney disease or renal professional or interested in the field - make sure you have liked/followed/pinned the nephrology feed
bsky.app/profile/did:...
Thanks again to @richardferro.xyz for creating & updating this! It’s a one-stop shop for nephrology needs
#NephSky
bsky.app/profile/did:...
Thanks again to @richardferro.xyz for creating & updating this! It’s a one-stop shop for nephrology needs
#NephSky
Update
Link changed (will not change again)
So if you liked/pinned the old feed, please do it again!
bsky.app/profile/did:...
#NephSky
Link changed (will not change again)
So if you liked/pinned the old feed, please do it again!
bsky.app/profile/did:...
#NephSky
Reposted by Swapnil Hiremath 🍁🇨🇦
Disturbingly detailed analysis of my first rewatch incoming
February 9, 2026 at 2:30 AM
Disturbingly detailed analysis of my first rewatch incoming
Reposted by Swapnil Hiremath 🍁🇨🇦
Arterial Stiffness and Central Hemodynamics in South Asian, African American, and White Adolescents and Young Adults—The Charisma Study
🔗 academic.oup.com/ajh/article-... 🔒
🔗 academic.oup.com/ajh/article-... 🔒
Arterial Stiffness and Central Hemodynamics in South Asian, African American, and White Adolescents and Young Adults—The Charisma Study
AbstractBACKGROUND. Compared to individuals of European or African ancestry, individuals of South Asian (SA) ancestry have greater cardiovascular disease (
academic.oup.com
February 9, 2026 at 11:01 AM
Arterial Stiffness and Central Hemodynamics in South Asian, African American, and White Adolescents and Young Adults—The Charisma Study
🔗 academic.oup.com/ajh/article-... 🔒
🔗 academic.oup.com/ajh/article-... 🔒
Reposted by Swapnil Hiremath 🍁🇨🇦
A secondary analysis of the TESTING trial predicted individual patient response to corticosteroid treatment in IgA nephropathy
#nephsky
#nephsky
A secondary analysis of the TESTING trial predicted individual patient response to corticosteroid treatment in IgA nephropathy
Corticosteroids are effective for treating IgA nephropathy but have important adverse effects. In this secondary analysis of the TESTING cohort, we generated a model to predicts, for an individual…
buff.ly
February 9, 2026 at 12:00 AM
A secondary analysis of the TESTING trial predicted individual patient response to corticosteroid treatment in IgA nephropathy
#nephsky
#nephsky
Reposted by Swapnil Hiremath 🍁🇨🇦
Urine microalbumin getting Super Bowl star treatment with Sofia Vergara and Octavia Spencer.
February 9, 2026 at 1:37 AM
Urine microalbumin getting Super Bowl star treatment with Sofia Vergara and Octavia Spencer.
Reposted by Swapnil Hiremath 🍁🇨🇦
If you’re in 🇨🇦, have skin in the game for the Super Bowl outcome, and have Hypertension, check your amlodipine brand. globalnews.ca/news/1165789...
High blood pressure drug recalled over low blood pressure pill mix-up - National | Globalnews.ca
Health Canada is recalling two lots of MAR-Amlodipine after some bottles were found to contain midodrine, a medication used to treat low blood pressure.
globalnews.ca
February 9, 2026 at 12:44 AM
If you’re in 🇨🇦, have skin in the game for the Super Bowl outcome, and have Hypertension, check your amlodipine brand. globalnews.ca/news/1165789...
Reposted by Swapnil Hiremath 🍁🇨🇦
Hey #NephSky
2/10/26 at 9 pm EST we'll discuss
#Flozinating into the Future & Beyond...
SGLT2i in kidney transplant recipients.
What's the latest evidence of risk/benefit?
Do #Flozins act mechanistically the same in de-innervated kidneys?
Come chat.
www.nephjc.com/news/inifinti-flozins-transplant
2/10/26 at 9 pm EST we'll discuss
#Flozinating into the Future & Beyond...
SGLT2i in kidney transplant recipients.
What's the latest evidence of risk/benefit?
Do #Flozins act mechanistically the same in de-innervated kidneys?
Come chat.
www.nephjc.com/news/inifinti-flozins-transplant
To INFINITI and Beyond: SGLT2 Inhibitors in Kidney Transplant Patients — NephJC
This week, we aim for an INFINITe allograft lifespan. or flozination in kidney transplant.
www.nephjc.com
February 8, 2026 at 11:25 PM
Hey #NephSky
2/10/26 at 9 pm EST we'll discuss
#Flozinating into the Future & Beyond...
SGLT2i in kidney transplant recipients.
What's the latest evidence of risk/benefit?
Do #Flozins act mechanistically the same in de-innervated kidneys?
Come chat.
www.nephjc.com/news/inifinti-flozins-transplant
2/10/26 at 9 pm EST we'll discuss
#Flozinating into the Future & Beyond...
SGLT2i in kidney transplant recipients.
What's the latest evidence of risk/benefit?
Do #Flozins act mechanistically the same in de-innervated kidneys?
Come chat.
www.nephjc.com/news/inifinti-flozins-transplant
Reposted by Swapnil Hiremath 🍁🇨🇦
From Monday, by @josephinelee.bsky.social: "I regarded Pearland as a bleak place to endure as part of my sacrificial motherhood. So I was surprised to find a temple here where women were both being celebrated and celebrating with so much joy."
A Reporter's Religious Quest in Houston Suburbia
At a Hindu temple hidden in Pearland, I found lessons about community, womanhood, and alienation.
www.texasobserver.org
February 8, 2026 at 10:00 PM
From Monday, by @josephinelee.bsky.social: "I regarded Pearland as a bleak place to endure as part of my sacrificial motherhood. So I was surprised to find a temple here where women were both being celebrated and celebrating with so much joy."
Reposted by Swapnil Hiremath 🍁🇨🇦
#WeekendReads from the Archives
Trends in Blood Pressure Control among US Adults With Hypertension, 2013–2014 to 2021–2023
🔗 academic.oup.com/ajh/article/... 🔓
#openaccess #free
Trends in Blood Pressure Control among US Adults With Hypertension, 2013–2014 to 2021–2023
🔗 academic.oup.com/ajh/article/... 🔓
#openaccess #free
February 8, 2026 at 5:03 PM
#WeekendReads from the Archives
Trends in Blood Pressure Control among US Adults With Hypertension, 2013–2014 to 2021–2023
🔗 academic.oup.com/ajh/article/... 🔓
#openaccess #free
Trends in Blood Pressure Control among US Adults With Hypertension, 2013–2014 to 2021–2023
🔗 academic.oup.com/ajh/article/... 🔓
#openaccess #free
Reposted by Swapnil Hiremath 🍁🇨🇦
The United States has the highest incarceration rate in the world: nearly 2 million people locked up in 1,566 state prisons, 98 federal prisons, 3,116 local jails, 1,277 juvenile correctional facilities, 133 immigration detention facilities, 80 Indian country jails etc
February 8, 2026 at 4:37 PM
The United States has the highest incarceration rate in the world: nearly 2 million people locked up in 1,566 state prisons, 98 federal prisons, 3,116 local jails, 1,277 juvenile correctional facilities, 133 immigration detention facilities, 80 Indian country jails etc
Reposted by Swapnil Hiremath 🍁🇨🇦
This man didn’t believe in the Covid epidemic because he didn’t see that many ill people in his ER.
Source? His podcast.
Where he had panels w/ friends who thought similar. He also sold merch.
Don’t trust everything a “doctor” says.
Source? His podcast.
Where he had panels w/ friends who thought similar. He also sold merch.
Don’t trust everything a “doctor” says.
What supplements should you be taking? An Ottawa doctor has some advice
What supplements should you be taking? An Ottawa doctor has some advice
It can be difficult to know what supplements to take and why, but one Ottawa doctor has some advice.
bit.ly
February 8, 2026 at 1:57 PM
This man didn’t believe in the Covid epidemic because he didn’t see that many ill people in his ER.
Source? His podcast.
Where he had panels w/ friends who thought similar. He also sold merch.
Don’t trust everything a “doctor” says.
Source? His podcast.
Where he had panels w/ friends who thought similar. He also sold merch.
Don’t trust everything a “doctor” says.
Reposted by Swapnil Hiremath 🍁🇨🇦
Haven't read this yet, but my pretest probability this is true border on 100%. Cuts in clinic =/= cuts in clinical time. Visits longer/more complicated/more non-visit EMR work.
**nearly all academic MD/DO's have experienced this
www.healthaffairs.org/doi/abs/10.1...
**nearly all academic MD/DO's have experienced this
www.healthaffairs.org/doi/abs/10.1...
Changes In Primary Care Physicians’ Electronic Health Record Patterns After They Reduced Clinical Visit Volume | Health Affairs Journal
Primary care physicians face increasing workload pressures. Some are delivering fewer patient visits, potentially in response to these pressures. However, the relationship between reduced visit volume...
www.healthaffairs.org
February 8, 2026 at 12:20 PM
Haven't read this yet, but my pretest probability this is true border on 100%. Cuts in clinic =/= cuts in clinical time. Visits longer/more complicated/more non-visit EMR work.
**nearly all academic MD/DO's have experienced this
www.healthaffairs.org/doi/abs/10.1...
**nearly all academic MD/DO's have experienced this
www.healthaffairs.org/doi/abs/10.1...
-35 C tonight in Ottawa (-31 F)
getting close to when F = C (-40 C/F)
getting close to when F = C (-40 C/F)
a cartoon scene of a cabin in the snow with a canadian flag in the foreground
Alt: a cartoon scene of a cabin in the snow with a canadian flag in the foreground
media.tenor.com
February 8, 2026 at 1:44 AM
-35 C tonight in Ottawa (-31 F)
getting close to when F = C (-40 C/F)
getting close to when F = C (-40 C/F)
from @willdouglasheaven.bsky.social on the @moltbook.bsky.social frenzy
(and the Karpathy snippet was a fake)
more: www.technologyreview.com/2026/02/06/1... in @technologyreview.com
#LLMSlop
(and the Karpathy snippet was a fake)
more: www.technologyreview.com/2026/02/06/1... in @technologyreview.com
#LLMSlop
February 8, 2026 at 1:13 AM
from @willdouglasheaven.bsky.social on the @moltbook.bsky.social frenzy
(and the Karpathy snippet was a fake)
more: www.technologyreview.com/2026/02/06/1... in @technologyreview.com
#LLMSlop
(and the Karpathy snippet was a fake)
more: www.technologyreview.com/2026/02/06/1... in @technologyreview.com
#LLMSlop
Reposted by Swapnil Hiremath 🍁🇨🇦
The FDA used to warn people, on its website, not to drink raw camel’s milk for “treating” autism—as it is dangerous & there’s no good evidence it “works”
The warning has now gone
Since I’m a masochist, I’ve gone down a rabbit hole trying to understand where “camel’s milk for autism” began
1/2
The warning has now gone
Since I’m a masochist, I’ve gone down a rabbit hole trying to understand where “camel’s milk for autism” began
1/2
February 7, 2026 at 3:50 PM
The FDA used to warn people, on its website, not to drink raw camel’s milk for “treating” autism—as it is dangerous & there’s no good evidence it “works”
The warning has now gone
Since I’m a masochist, I’ve gone down a rabbit hole trying to understand where “camel’s milk for autism” began
1/2
The warning has now gone
Since I’m a masochist, I’ve gone down a rabbit hole trying to understand where “camel’s milk for autism” began
1/2
Reposted by Swapnil Hiremath 🍁🇨🇦
#WeekendReads from the advance articles section
The role of renal denervation for hypertension control in Canada: a case based discussion
academic.oup.com/ajh/advance-...
#OpenAccess #Free
The role of renal denervation for hypertension control in Canada: a case based discussion
academic.oup.com/ajh/advance-...
#OpenAccess #Free
The Role of Renal Denervation in the Treatment of Hypertension in Canada: A Case-Based Discussion from the Canadian Hypertension Specialists Society
Abstract. Over one-third of Canadians with hypertension do not achieve recommended blood pressure (BP) targets despite availability of effective treatments
academic.oup.com
February 7, 2026 at 4:00 PM
#WeekendReads from the advance articles section
The role of renal denervation for hypertension control in Canada: a case based discussion
academic.oup.com/ajh/advance-...
#OpenAccess #Free
The role of renal denervation for hypertension control in Canada: a case based discussion
academic.oup.com/ajh/advance-...
#OpenAccess #Free
Reposted by Swapnil Hiremath 🍁🇨🇦
I don’t want to laugh at a small business but also VERY funny
February 6, 2026 at 1:40 PM
I don’t want to laugh at a small business but also VERY funny
Reposted by Swapnil Hiremath 🍁🇨🇦
Have to opine, though. These are not primary FSGS per KDIGO definition (ie. permeability factor), but rather a combination of genetic FSGS, FSGS of undetermined cause, and perhaps a bit of secondary FSGS (despite thorough work-up).
Doubt that TRPC6i will work in an autoimmune condition…
Doubt that TRPC6i will work in an autoimmune condition…
February 7, 2026 at 1:45 PM
Have to opine, though. These are not primary FSGS per KDIGO definition (ie. permeability factor), but rather a combination of genetic FSGS, FSGS of undetermined cause, and perhaps a bit of secondary FSGS (despite thorough work-up).
Doubt that TRPC6i will work in an autoimmune condition…
Doubt that TRPC6i will work in an autoimmune condition…
Reposted by Swapnil Hiremath 🍁🇨🇦
Tumor nephrectomy with incidental ALECT2. Interestingly this was from a pt from India. Reminder that a subset of ALECT2 cases have been reported in Punjabi patients (pubmed.ncbi.nlm.nih.gov/35986199/) . #renalpath #pathsky #nephsky
February 6, 2026 at 7:31 PM
Tumor nephrectomy with incidental ALECT2. Interestingly this was from a pt from India. Reminder that a subset of ALECT2 cases have been reported in Punjabi patients (pubmed.ncbi.nlm.nih.gov/35986199/) . #renalpath #pathsky #nephsky
Reposted by Swapnil Hiremath 🍁🇨🇦
CKD isn’t a very common disorder seen in pandas. More are hypertensive without CKD but I don’t know if the cause is well known or fully investigated.
February 6, 2026 at 5:44 PM
CKD isn’t a very common disorder seen in pandas. More are hypertensive without CKD but I don’t know if the cause is well known or fully investigated.
Reposted by Swapnil Hiremath 🍁🇨🇦
The American Board of Internal Medicine has started a pilot program allowing international medical graduates who completed their residency abroad to become board eligible after fellowship training in the US. Read more in #ASNKidneyNews: kidney.pub/KN1801-14 KatieOverV
February 6, 2026 at 3:00 PM
The American Board of Internal Medicine has started a pilot program allowing international medical graduates who completed their residency abroad to become board eligible after fellowship training in the US. Read more in #ASNKidneyNews: kidney.pub/KN1801-14 KatieOverV
Reposted by Swapnil Hiremath 🍁🇨🇦
1Password not mincing words here:
"If you are experimenting with OpenClaw, do not do it on a company device. Full stop."
"If you have already run OpenClaw on a work device, treat it as a potential incident and engage your security team immediately."
1password.com/blog/from-ma...
"If you are experimenting with OpenClaw, do not do it on a company device. Full stop."
"If you have already run OpenClaw on a work device, treat it as a potential incident and engage your security team immediately."
1password.com/blog/from-ma...
From magic to malware: How OpenClaw's agent skills become an attack surface | 1Password
The same capabilities that make OpenClaw a groundbreaking tool also make it an urgent security risk. This blog contains confirmed examples of agent skills being used as malware vectors, and advice on ...
1password.com
February 3, 2026 at 1:12 PM
1Password not mincing words here:
"If you are experimenting with OpenClaw, do not do it on a company device. Full stop."
"If you have already run OpenClaw on a work device, treat it as a potential incident and engage your security team immediately."
1password.com/blog/from-ma...
"If you are experimenting with OpenClaw, do not do it on a company device. Full stop."
"If you have already run OpenClaw on a work device, treat it as a potential incident and engage your security team immediately."
1password.com/blog/from-ma...
moving on from IgAN to FSGS: BI 764198 a TRPC6 inhibitor reduces proteinuria in an N = 67 phase 2 RCT
www.thelancet.com/journals/lan...
in @thelancet.com
#NephSky
www.thelancet.com/journals/lan...
in @thelancet.com
#NephSky
TRPC6 inhibition for the treatment of focal segmental glomerulosclerosis: a randomised, placebo-controlled, phase 2 trial of BI 764198
BI 764198 lowered proteinuria and was well tolerated by participants in this trial.
This is the first evidence of efficacy with a podocyte-targeted therapy in FSGS. Larger
randomised controlled trials...
www.thelancet.com
February 6, 2026 at 11:12 AM
moving on from IgAN to FSGS: BI 764198 a TRPC6 inhibitor reduces proteinuria in an N = 67 phase 2 RCT
www.thelancet.com/journals/lan...
in @thelancet.com
#NephSky
www.thelancet.com/journals/lan...
in @thelancet.com
#NephSky
Reposted by Swapnil Hiremath 🍁🇨🇦
Childhood Obesity Raises GDM Risk Through Adult Obesity: Evidence From Lifecourse Mendelian Randomization Study
🔗 academic.oup.com/ajh/article-... 🔒
🔗 academic.oup.com/ajh/article-... 🔒
Childhood Obesity Raises GDM Risk Through Adult Obesity: Evidence From Lifecourse Mendelian Randomization Study
AbstractBACKGROUND. The relationship between childhood and adulthood obesity and the risk of gestational diabetes mellitus (GDM) remains unclear. To clarif
academic.oup.com
February 6, 2026 at 11:02 AM
Childhood Obesity Raises GDM Risk Through Adult Obesity: Evidence From Lifecourse Mendelian Randomization Study
🔗 academic.oup.com/ajh/article-... 🔒
🔗 academic.oup.com/ajh/article-... 🔒
Reposted by Swapnil Hiremath 🍁🇨🇦
Does anyone have experience with angiotensin 2 during septic shock?
@pulmcrit.bsky.social @zentensivist.bsky.social @drfreeze.bsky.social @load-dependent.bsky.social @hswapnil.medsky.social
@pulmcrit.bsky.social @zentensivist.bsky.social @drfreeze.bsky.social @load-dependent.bsky.social @hswapnil.medsky.social
February 6, 2026 at 9:09 AM
Does anyone have experience with angiotensin 2 during septic shock?
@pulmcrit.bsky.social @zentensivist.bsky.social @drfreeze.bsky.social @load-dependent.bsky.social @hswapnil.medsky.social
@pulmcrit.bsky.social @zentensivist.bsky.social @drfreeze.bsky.social @load-dependent.bsky.social @hswapnil.medsky.social