Lightnews — Scholar-powered news

Kira Gritsman @gritsmanlab.bsky.social · Sep 2

Thank you, Julio!

Kira Gritsman @gritsmanlab.bsky.social · Aug 28

Happy to contribute to this exciting project just published in @nature.com led by the amazing Shoichiro Takeishi in a fantastic collaboration with @steidluli.bsky.social - check out this thread 🩸 🧬

Uli Steidl @steidluli.bsky.social · Aug 28

Please check out this thread on our latest paper in
@nature.com on HSC pool size regulation. rdcu.be/eCJLe
Phenomenal collaboration with @gritsmanlab.bsky.social, and driven by the outstanding Shoichiro Takeishi! @einsteincellbio.bsky.social
@einsteinmededu.bsky.social (1/6)

Haematopoietic stem cell number is not solely defined by niche availability

Nature - Haematopoietic stem cell numbers are restricted at both systemic and local levels.

rdcu.be

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Reposted by Kira Gritsman

Dr. Dawn Wright @deepseadawn.bsky.social · Aug 1

Glimmer of hope: the Senate Labor, Health and Human Services Subcommittee just voted, 26 to 3, to reject the administration’s proposed cuts & instead recommend a $400 million increase to the NIH budget. The House LHHS Subcommittee convenes in September
www.appropriations.senate.gov/news/minorit...
🧪

Senate Appropriations Committee Approves Defense and Labor, Health and Human Services, and Education Bills | United States Senate Committee on Appropriations

United States Senate Committee on Appropriations

www.appropriations.senate.gov

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Reposted by Kira Gritsman

Heme Queen @heme-queen.bsky.social · Jul 31

So impressed at the increased support the American Society of Hematology is planning for trainees and early-career investigators!! At some point, someone invested in us. Now it’s our turn. #Fight4Hematology and secure the future of hematology research. Donate! #hemesky www.hematology.org/foundation

ASH Foundation

The ASH Foundation is dedicated to moving hematology forward through charitable support for ASH programs â€“ helping hematologists conquer blood diseases worldwide.

www.hematology.org

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Reposted by Kira Gritsman

American Society of Hematology @ash.hematology.org · Jul 31

Interested in a mentor to guide your career in malignant hematology? Apply for the ASH’s new Mentorship Program, and grow your network! Deadline: Sept 26. Apply today! 🔗 https://bit.ly/3IPWjMA

Interested in becoming a mentor? Sign up today: https://bit.ly/3U5tm1t

#HemeSky

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Reposted by Kira Gritsman

ernstlaboratory.bsky.social @ernstlaboratory.bsky.social · Jul 21

The Myeloid Workshop is back in ASH! Please contact the organizers if you have an exciting story that will not be out by December they are: Zuzana Tothova ,
@ernstlaboratory.bsky.social
@steidluli.bsky.social
@ericpietras.bsky.social
@kathrinbernt.bsky.social
@gritsmanlab.bsky.social

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Kira Gritsman @gritsmanlab.bsky.social · Jul 16

Thank you

Kira Gritsman @gritsmanlab.bsky.social · Jul 16

Check out our new preprint on an epigenetic resistance mechanism to PI3 kinase inhibition in AML and a new combination therapy with an EZH1/2 inhibitor that depletes leukemic stem cells! Great effort by @thehematopoet and the whole team

Shira G-S, PhD @thehematopoet.bsky.social · Jul 15

So excited to share a pre-print of my thesis work! Check it out to see how we can leverage an epigenetic resistance mechanism to PI3K inhibitors to target leukemic stem cells!! (Spoiler alert: PRC2 is involved!) Really proud of this work conducted with @gritsmanlab.bsky.social

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · Jul 15

Exploiting an Epigenetic Resistance Mechanism to PI3 Kinase Inhibition in Leukemic Stem Cells https://www.biorxiv.org/content/10.1101/2025.07.11.663968v1

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Kira Gritsman @gritsmanlab.bsky.social · Apr 10

Thanks Adrienne!

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Kira Gritsman @gritsmanlab.bsky.social · Apr 10

So excited that our collaboration with the Shechter lab on a new targetable PTM -glutamylation- on NPM1c in AML is now on BioRxiv! Team effort led by @alexkschurer.bsky.social and @humaira2204.bsky.social! 🧪🩸

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Reposted by Kira Gritsman

American Society of Hematology @ash.hematology.org · Mar 21

#NIHfunding cuts have resulted in stalled research. In response, ASH is expanding its Bridge Grant Program with $150K in awards to support critical research by members. Donate to support #hematology researchers and help ensure innovative research continues: https://bit.ly/41LFwjD

#HemeSky #MedSky

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Reposted by Kira Gritsman

The Unpatriotic Misanthrope who Protests @vcalemine.bsky.social · Mar 11

If you have applied to an R01 or equivalent, please check out the new eligibility. #hematology #medsky #phdsky #scisky #science

American Society of Hematology @ash.hematology.org · Mar 10

In response to changes in the #NIHfunding, ASH is expanding access and eligibility for the 2025 Bridge Grant Program for #researchers.

Ready to enhance your career? Apply today: https://bit.ly/3F55fvz

#ASHAwards #Hematology #Grants #Hemesky #Fight4Hematolog

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Reposted by Kira Gritsman

Rick Huganir @rhuganir.bsky.social · Feb 15

I have been talking to the media, Time, Fortune, NBC, etc., to explain how the onslaught on science and NIH will impact the health of all Americans. Everyone knows someone who has cancer, heart disease, or depression. Spread the word about how cutting science impacts all.
time.com/7216299/nih-...

Experts Call NIH Budget Cuts an 'Apocalypse' for Science

The reductions target indirect costs that cover administrative and equipment costs.

time.com

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Reposted by Kira Gritsman

American Society of Hematology @ash.hematology.org · Feb 14

📢 Support federal research funding!

As the new Administration acts & Congress finalizes FY25 funding, lawmakers need to hear from you. Share your stories of how funding & policies impact #hematology patients & research.

Take action! bit.ly/4b2bj43

#Fight4Hematology #HemeSky #BloodSky

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Reposted by Kira Gritsman

American Society of Hematology @ash.hematology.org · Jan 28

Calling all aspiring hematologists in med school — don’t leave research funding on the table! 💰

✨ HIP Medical Student Award

✨ HONORS Award

✨ Physician-Scientist Award

Learn more: https://bit.ly/4hexNk7. Your application is due on Feb. 14!

#ASHTrainee #HemeSky #BloodSky #Hematology

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Kira Gritsman @gritsmanlab.bsky.social · Jan 22

Congratulations to all the new ASH Scholars!

American Society of Hematology @ash.hematology.org · Jan 21

#ASHKudos to the 2025 ASH Scholar Award recipients!

This award supports early career investigators as they transition from training programs to careers as independent investigators.

Learn more: https://bit.ly/4haW3Ue

#ASHAwards #Hematology #HemeSky #BloodSky @b-avalos-md.bsky.social

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Kira Gritsman @gritsmanlab.bsky.social · Jan 22

Congrats Courtney!

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Reposted by Kira Gritsman

Ann Mullally @mullallylab.bsky.social · Jan 10

Delighted to share our #hematology review article on mutant calreticulin in #MPN
Congrats to co-authors Drs. Mifra Faiz, Merle Riedemann & Jonas Jutzi. We hope it’s a useful resource, link below! @stanforddeptmed.bsky.social
link.springer.com/article/10.1...

Mutant Calreticulin in MPN: Mechanistic Insights and Therapeutic Implications - Current Hematologic Malignancy Reports

Purpose of Review More than a decade following the discovery of Calreticulin (CALR) mutations as drivers of myeloproliferative neoplasms (MPN), advances in the understanding of CALR-mutant MPN continu...

link.springer.com

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Reposted by Kira Gritsman

RUNX1 Research Program @runx1-fpd.org · Jan 9

Inflammation plays a key role in RUNX1-FPD pathogenesis. Dr. Anupriya Agarwal & her team at @ohsunews.bsky.social found targeting CD74 signaling, mTOR & JAK1/2 pathways could prevent disease progression. Incredible work by an RRP-EdwardPEvansFdn FIRE grant recipient! www.science.org/doi/10.1126/...

Targeting the CD74 signaling axis suppresses inflammation and rescues defective hematopoiesis in RUNX1-familial platelet disorder

CD74 signaling drives inflammation and differentiation defects in hematopoietic stem and progenitor cells in RUNX1-familial platelet disorder.

www.science.org

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Reposted by Kira Gritsman

Ann Mullally @mullallylab.bsky.social · Dec 9

Stanford #Hematology is recruiting! #ASH24 attendees, pls reach out to me if interested! 👇🏽@stanforddeptmed.bsky.social

Ann Mullally @mullallylab.bsky.social · Nov 24

Stanford Hematology is recruiting a physician-scientist in heme malignancies, details below, pls share, pls reach out with Qs, I’m excited to grow our amazing Division! @stanforddeptmed.bsky.social

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Reposted by Kira Gritsman

Stephen Oh @mpndoc.bsky.social · Dec 6

Excited for this workshop this afternoon and grateful to the organizers Christina Glytsou, Panos Ntziachristos, & Dan Starczynowski for the opportunity to speak in the session alongside @gritsmanlab.bsky.social & Marek Mraz! #ASH24 #hemesky @ash-hematology.bsky.social
ash.confex.com/ash/2024/web...

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Reposted by Kira Gritsman

Shira G-S, PhD @thehematopoet.bsky.social · Dec 6

So sad I am missing #ASH2024 But if you’re there early enough be sure to check out the wonderful @gritsmanlab.bsky.social present exciting updates from my work at the therapy resistance workshop on Friday! 2-5pm in SDCC room 33!

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Kira Gritsman @gritsmanlab.bsky.social · Dec 4

Check out our new review by the amazing @alexkschurer.bsky.social and @thehematopoet.bsky.social on chromatin modifiers in AML! Just in time for the first menin inhibitor FDA approval! 🧪🩸

Shira G-S, PhD @thehematopoet.bsky.social · Dec 4

Overwhelmed by all of the exciting new research on chromatin modifiers in AML? Find it hard to keep track of all the new menin inhibitors? Well good news, we’ve just published the perfect review for you in SCTM!

@alexkschurer.bsky.social
@gritsmanlab.bsky.social

academic.oup.com/stcltm/advan...

Targeting chromatin modifying complexes in acute myeloid leukemia

Abstract. Acute myeloid leukemia (AML) is a devastating hematologic malignancy with high rates of relapse, which can, in part, be attributed to the dysregu

academic.oup.com

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Kira Gritsman @gritsmanlab.bsky.social · Nov 28

Yes!

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Reposted by Kira Gritsman

Johanna Joyce @johannajoyce.bsky.social · Nov 25

Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️

So how can we ever achieve #gender #equality?

We discuss various strategies in this #Cell Commentary

#WomeninSTEM

www.cell.com/cell/fulltex...
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