Researchers Ai Yamamoto & Katherine Croce examine in HD mice the ALFY gene that slows HD's onset by up to 23 years, making it one of the most potent disease onset modifiers & an attractive therapeutic target. Congrats to the team!

Read the full article here: www.sciencedirect.com/science/arti...

Watch anytime! Our $1m Transformative Research Award recipients are pursuing innovative strategies to target the triggers of HD & open new pathways for potential treatments. Learn more: hdfoundation.org/webinars-eve...

Thanks to our sponsors, #IonisPharmaceuticals #ClevelandClinic #Novartis #Rgenta

This is an exciting time for the HDF - learn more at hdfoundation.org
#curehd

"Congratulations to the global Huntington's disease community. This result belongs to everyone." @profwild.bsky.social #curehd

www.youtube.com/watch?v=bhEx...

We are thrilled to celebrate this morning's historic announcement from uniQure showing positive results in their gene therapy trial for #Huntingtonsdisease, the first time any drug has been shown to alter the course of HD in a clinical trial. #curehd

uniqure.gcs-web.com/news-release...

Researchers have discovered genetic "messages" that may appear only when HD is active. Would silencing these messages stop HD? Learn more on Wed, 9/17, 12-1pm ET. Register: tinyurl.com/9-2025-webinar
Thanks to our sponsors, #IonisPharmaceuticals #ClevelandClinic #Novartis #Rgenta #researchspotlight

Beyond deserved, Jeff!

HDF 2024 Transformative Research Award winners uncovered 2 genetic clues only in people with HD with treatment potential. Learn more on Wed, 9/17, 12-1pm ET.
Register: tinyurl.com/9-2025-webinar
Thanks to our sponsors, #IonisPharmaceuticals #ClevelandClinic #Novartis #Rgenta #researchspotlight

Excited to announce the publication of a special issue on "Glia and non-neuronal cells in Huntington’s disease" that I co-edited with Dr. Asa Petersen in the Journal of Huntington's Disease (Volume 14, Issue 3)!

journals.sagepub.com/toc/huna/14/3

1/3

Congrats @jcarroll42.bsky.social, 2025 recipient of the Leslie Gehry Prize for Innovation in Science! Jeff's personal connection to #Huntingtonsdisease has fueled an impactful scientific career and an unwavering commitment to the HD community. We're so proud!

Learn more: tinyurl.com/2025-Gehry-P...

Our $1m Transformative Research Award winners think beyond the htt gene by targeting new molecules that may drive the disease. Learn more on Wed, 9/17, 12-1pm ET.
Register: tinyurl.com/9-2025-webinar
Thanks to our sponsors, #IonisPharmaceuticals #ClevelandClinic #Novartis #Rgenta #researchspotlight

We’re proud to announce Nicolo Zarotti as a 2025 HDBuzz Prize winner! He covers a case study shows that Acceptance & Commitment Therapy (ACT) can lift mood, improve quality of life for people with HD, and offer real support for caregivers too.

en.hdbuzz.net/2025-hdbuzz-...

Can we treat HD by targeting its triggers? Join us on Wed, 9/17, 12-1pm ET to find out!
Webinar with Drs. Andrew Yoo & Osama Al Dalahmah. Live Q&A to follow.
Register: us06web.zoom.us/.../651.../W...
Thanks to our sponsors, #IonisPharmaceuticals #ClevelandClinic #Novartis #Rgenta #researchspotlight

Congratulations to HDF Scientific Advisory Board member Gillian Bates FRS, on being is awarded the prestigious 2025 Ferrier Medal from the Royal Society royalsociety.org/medals-and-p...

An article from the lab of HDF Scientific Advisory Board Chair Dr. Leslie Thompson garners the cover of the prestigious journal Neuron. This new study takes a deep dive using cutting-edge single-cell and spatial genomics into how Huntington’s disease changes the brain over time.

We are pleased to announce Christopher E. Pearson, PhD, from the Hospital for Sick Children (SickKids)‪, Toronto, Canada, as the recipient of our $1 Million 2025 Transformative Research Award. @sickkidsto.bsky.social @utoronto.ca

Read the full press release: hdfoundation.org/2025-transfo...

HDF is currently accepting Letters of Intent for Postdoctoral Fellowships and Grants from researchers from around the world to advance the discovery and development of treatments for Huntington’s disease. Please visit our website: hdfoundation.org/apply/ to learn more. LOIs are due by 9/3/2025.